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United States Pharmaceuticals

Inspire Pharmaceuticals Inc (ISPH)

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Ticker: ISPH Exchange: NSQ
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
FREY KIP
7 sales — total 57,698 USD
Sale 15 Nov 2010
Value US$4,346,177.92 | Price 274.57 | Shares 91,046
Sale 15 Nov 2010
Value US$3,698,751.48 | Price 396.57 | Shares 64,737
Sale 15 Nov 2010
Value US$3,789.61 | Price 7.33 | Shares 517
Sale 15 Nov 2010
Value US$16,787.68 | Price 7.28 | Shares 2,306
Sale 15 Nov 2010
Value US$7,240.92 | Price 7.27 | Shares 996
Sale 15 Nov 2010
Value US$1,437.48 | Price 7.26 | Shares 198
Sale 15 Nov 2010
Value US$24,896.50 | Price 7.25 | Shares 3,434
Buy 9 Nov 2010
Value US$4,265,513.38 | Price 254.46 | Shares 29,542
Buy 9 Nov 2010
Value US$711,383.99 | Price 63.80 | Shares 31,783
Planned sale 3 May 2010
Value US$2,870.01 | Price 6.69 | Shares 429
Planned sale 3 May 2010
Value US$3,825.70 | Price 6.70 | Shares 571
Planned sale 3 May 2010
Value US$1,350.00 | Price 6.75 | Shares 200
Planned sale 3 May 2010
Value US$676.00 | Price 6.76 | Shares 100
Planned sale 3 May 2010
Value US$2,031.00 | Price 6.77 | Shares 300
Planned sale 3 May 2010
Value US$1,091.58 | Price 6.78 | Shares 161
Planned sale 3 May 2010
Value US$264.81 | Price 6.79 | Shares 39
Planned sale 3 May 2010
Value US$680.00 | Price 6.80 | Shares 100
Planned sale 1 Apr 2010
Value US$3,243.75 | Price 6.25 | Shares 519
Planned sale 1 Apr 2010
Value US$1,890.00 | Price 6.30 | Shares 300
Planned sale 1 Apr 2010
Value US$1,640.60 | Price 6.31 | Shares 260
Planned sale 1 Apr 2010
Value US$1,264.00 | Price 6.32 | Shares 200
Planned sale 1 Mar 2010
Value US$756.40 | Price 6.10 | Shares 124
Planned sale 1 Mar 2010
Value US$611.00 | Price 6.11 | Shares 100
Planned sale 1 Mar 2010
Value US$3,530.88 | Price 6.13 | Shares 576
Planned sale 1 Mar 2010
Value US$614.00 | Price 6.14 | Shares 100
Planned sale 1 Mar 2010
Value US$3,714.60 | Price 6.15 | Shares 604
Planned sale 1 Feb 2010
Value US$6,480.00 | Price 5.40 | Shares 1,200
Planned sale 1 Feb 2010
Value US$2,461.55 | Price 5.41 | Shares 455
Planned sale 1 Feb 2010
Value US$244.35 | Price 5.43 | Shares 45
Planned sale 1 Feb 2010
Value US$544.00 | Price 5.44 | Shares 100
Planned sale 4 Jan 2010
Value US$555.00 | Price 5.55 | Shares 100
Planned sale 4 Jan 2010
Value US$524.52 | Price 5.58 | Shares 94
Planned sale 4 Jan 2010
Value US$592.54 | Price 5.59 | Shares 106
Planned sale 4 Jan 2010
Value US$1,120.00 | Price 5.60 | Shares 200
Planned sale 4 Jan 2010
Value US$6,171.00 | Price 5.61 | Shares 1,100
Planned sale 8 Dec 2009
Value US$21,000.00 | Price 6.00 | Shares 3,500
Planned sale 1 Dec 2009
Value US$563.00 | Price 5.63 | Shares 100
Planned sale 1 Dec 2009
Value US$565.00 | Price 5.65 | Shares 100
Planned sale 1 Dec 2009
Value US$1,132.00 | Price 5.66 | Shares 200
Planned sale 1 Dec 2009
Value US$1,704.00 | Price 5.68 | Shares 300
Planned sale 1 Dec 2009
Value US$1,138.00 | Price 5.69 | Shares 200
Planned sale 1 Dec 2009
Value US$1,607.40 | Price 5.70 | Shares 282
Planned sale 1 Dec 2009
Value US$1,142.00 | Price 5.71 | Shares 200
Planned sale 1 Dec 2009
Value US$1,716.00 | Price 5.72 | Shares 300
Planned sale 1 Dec 2009
Value US$573.00 | Price 5.73 | Shares 100
Planned sale 1 Dec 2009
Value US$287.00 | Price 5.74 | Shares 50
Planned sale 2 Nov 2009
Value US$1,362.00 | Price 4.54 | Shares 300
Planned sale 2 Nov 2009
Value US$2,730.00 | Price 4.55 | Shares 600
Planned sale 2 Nov 2009
Value US$4,104.00 | Price 4.56 | Shares 900
Planned sale 1 Oct 2009
Value US$1,034.00 | Price 5.17 | Shares 200
Planned sale 1 Oct 2009
Value US$2,076.00 | Price 5.19 | Shares 400
Planned sale 1 Oct 2009
Value US$1,560.00 | Price 5.20 | Shares 300
Planned sale 1 Sep 2009
Value US$269.76 | Price 5.62 | Shares 48
Planned sale 1 Sep 2009
Value US$5,670.00 | Price 5.67 | Shares 1,000
Planned sale 1 Sep 2009
Value US$3,135.36 | Price 5.68 | Shares 552
Planned sale 1 Sep 2009
Value US$569.00 | Price 5.69 | Shares 100
Planned sale 1 Sep 2009
Value US$780.90 | Price 5.70 | Shares 137
Planned sale 1 Sep 2009
Value US$571.00 | Price 5.71 | Shares 100
Planned sale 24 Aug 2009
Value US$22,237.00 | Price 6.01 | Shares 3,700
Planned sale 24 Aug 2009
Value US$17,458.00 | Price 6.02 | Shares 2,900
Planned sale 24 Aug 2009
Value US$7,236.00 | Price 6.03 | Shares 1,200
Planned sale 24 Aug 2009
Value US$2,416.00 | Price 6.04 | Shares 400
Buy 10 Aug 2009
Value US$39,999,996.00 | Price 4.50 | Shares 8,888,888
Buy 10 Aug 2009
Value US$39,999,996.00 | Price 4.50 | Shares 8,888,888
Planned sale 3 Aug 2009
Value US$461.00 | Price 4.61 | Shares 100
Planned sale 3 Aug 2009
Value US$468.00 | Price 4.68 | Shares 100
Planned sale 3 Aug 2009
Value US$942.00 | Price 4.71 | Shares 200
Planned sale 3 Aug 2009
Value US$1,416.00 | Price 4.72 | Shares 300
Planned sale 3 Aug 2009
Value US$479.00 | Price 4.79 | Shares 100
Planned sale 3 Aug 2009
Value US$2,303.96 | Price 4.82 | Shares 478
Planned sale 3 Aug 2009
Value US$106.48 | Price 4.84 | Shares 22
Planned sale 3 Aug 2009
Value US$976.00 | Price 4.88 | Shares 200
Planned sale 3 Aug 2009
Value US$988.00 | Price 4.94 | Shares 200
Planned sale 3 Aug 2009
Value US$496.00 | Price 4.96 | Shares 100
Planned sale 3 Aug 2009
Value US$500.00 | Price 5.00 | Shares 100
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2010-11-17 2010-11-15 S Sale FREY KIP Non-Executive Director
91,046 +0.9%
274.57
US$4,346,178 		91,046 +0.9% 274.57 US$4,346,178
2010-11-17 2010-11-15 S Sale FREY KIP Non-Executive Director
64,737 -10.5%
396.57
US$3,698,751 		64,737 -10.5% 396.57 US$3,698,751
2010-11-17 2010-11-15 S Sale FREY KIP Non-Executive Director
55,342 +35.7%
77.32
US$4,671,092 		55,342 +35.7% 77.32 US$4,671,092
2010-11-17 2010-11-15 S Sale FREY KIP Non-Executive Director
2,306 -69.8%
7.28
US$16,788 		2,306 -69.8% 7.28 US$16,788
2010-11-17 2010-11-15 S Sale FREY KIP Non-Executive Director
996 -23.2%
7.27
US$7,241 		996 -23.2% 7.27 US$7,241
2010-11-17 2010-11-15 S Sale FREY KIP Non-Executive Director
198 -4.4%
7.26
US$1,437 		198 -4.4% 7.26 US$1,437
2010-11-17 2010-11-15 S Sale FREY KIP Non-Executive Director
3,434 -43.3%
7.25
US$24,896 		3,434 -43.3% 7.25 US$24,896
2010-11-12 2010-11-09 B Purchase Hutson Nancy J Non-Executive Director
5,400 +57.4%
6.99
US$37,746 		5,400 +57.4% 6.99 US$37,746
2010-11-12 2010-11-09 B Purchase Hutson Nancy J Non-Executive Director
1,600 +20.5%
6.98
US$11,168 		1,600 +20.5% 6.98 US$11,168
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
429 -0.8%
6.69
US$2,870 		429 -0.8% 6.69 US$2,870
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
571 -1.1%
6.70
US$3,826 		571 -1.1% 6.70 US$3,826
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.4%
6.75
US$1,350 		200 -0.4% 6.75 US$1,350
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
6.76
US$676 		100 -0.2% 6.76 US$676
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
300 -0.6%
6.77
US$2,031 		300 -0.6% 6.77 US$2,031
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
161 -0.3%
6.78
US$1,092 		161 -0.3% 6.78 US$1,092
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
39 -0.1%
6.79
US$265 		39 -0.1% 6.79 US$265
2010-05-05 2010-05-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
6.80
US$680 		100 -0.2% 6.80 US$680
2010-04-05 2010-04-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
519 -0.9%
6.25
US$3,244 		519 -0.9% 6.25 US$3,244
2010-04-05 2010-04-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
300 -0.5%
6.30
US$1,890 		300 -0.5% 6.30 US$1,890
2010-04-05 2010-04-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
260 -0.5%
6.31
US$1,641 		260 -0.5% 6.31 US$1,641
2010-04-05 2010-04-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.4%
6.32
US$1,264 		200 -0.4% 6.32 US$1,264
2010-03-03 2010-03-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
124 -0.2%
6.10
US$756 		124 -0.2% 6.10 US$756
2010-03-03 2010-03-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
6.11
US$611 		100 -0.2% 6.11 US$611
2010-03-03 2010-03-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
576 -1.0%
6.13
US$3,531 		576 -1.0% 6.13 US$3,531
2010-03-03 2010-03-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
6.14
US$614 		100 -0.2% 6.14 US$614
2010-03-03 2010-03-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
604 -1.0%
6.15
US$3,715 		604 -1.0% 6.15 US$3,715
2010-02-02 2010-02-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
1,200 -2.0%
5.40
US$6,480 		1,200 -2.0% 5.40 US$6,480
2010-02-02 2010-02-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
455 -0.8%
5.41
US$2,462 		455 -0.8% 5.41 US$2,462
2010-02-02 2010-02-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
45 -0.1%
5.43
US$244 		45 -0.1% 5.43 US$244
2010-02-02 2010-02-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
5.44
US$544 		100 -0.2% 5.44 US$544
2010-01-05 2010-01-04 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
5.55
US$555 		100 -0.2% 5.55 US$555
2010-01-05 2010-01-04 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
94 -0.2%
5.58
US$525 		94 -0.2% 5.58 US$525
2010-01-05 2010-01-04 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
106 -0.2%
5.59
US$593 		106 -0.2% 5.59 US$593
2010-01-05 2010-01-04 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
5.60
US$1,120 		200 -0.3% 5.60 US$1,120
2010-01-05 2010-01-04 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
1,100 -1.8%
5.61
US$6,171 		1,100 -1.8% 5.61 US$6,171
2009-12-08 2009-12-08 PlS Planned sale SHAFFER CHRISTY L

President & CEO

Executive Director
3,500 -1.0%
6.00
US$21,000 		3,500 -1.0% 6.00 US$21,000
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
5.63
US$563 		100 -0.2% 5.63 US$563
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
5.65
US$565 		100 -0.2% 5.65 US$565
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
5.66
US$1,132 		200 -0.3% 5.66 US$1,132
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
300 -0.5%
5.68
US$1,704 		300 -0.5% 5.68 US$1,704
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
5.69
US$1,138 		200 -0.3% 5.69 US$1,138
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
282 -0.4%
5.70
US$1,607 		282 -0.4% 5.70 US$1,607
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
5.71
US$1,142 		200 -0.3% 5.71 US$1,142
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
300 -0.5%
5.72
US$1,716 		300 -0.5% 5.72 US$1,716
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.2%
5.73
US$573 		100 -0.2% 5.73 US$573
2009-12-02 2009-12-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
50 -0.1%
5.74
US$287 		50 -0.1% 5.74 US$287
2009-11-03 2009-11-02 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
300 -0.5%
4.54
US$1,362 		300 -0.5% 4.54 US$1,362
2009-11-03 2009-11-02 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
600 -0.9%
4.55
US$2,730 		600 -0.9% 4.55 US$2,730
2009-11-03 2009-11-02 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
900 -1.4%
4.56
US$4,104 		900 -1.4% 4.56 US$4,104
2009-10-01 2009-10-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
5.17
US$1,034 		200 -0.3% 5.17 US$1,034
2009-10-01 2009-10-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
400 -0.6%
5.19
US$2,076 		400 -0.6% 5.19 US$2,076
2009-10-01 2009-10-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
300 -0.4%
5.20
US$1,560 		300 -0.4% 5.20 US$1,560
2009-09-01 2009-09-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
48 -0.1%
5.62
US$270 		48 -0.1% 5.62 US$270
2009-09-01 2009-09-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
1,000 -1.4%
5.67
US$5,670 		1,000 -1.4% 5.67 US$5,670
2009-09-01 2009-09-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
552 -0.8%
5.68
US$3,135 		552 -0.8% 5.68 US$3,135
2009-09-01 2009-09-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.1%
5.69
US$569 		100 -0.1% 5.69 US$569
2009-09-01 2009-09-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
137 -0.2%
5.70
US$781 		137 -0.2% 5.70 US$781
2009-09-01 2009-09-01 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.1%
5.71
US$571 		100 -0.1% 5.71 US$571
2009-08-25 2009-08-24 PlS Planned sale SHAFFER CHRISTY L

President & CEO

Executive Director
3,700 -1.0%
6.01
US$22,237 		3,700 -1.0% 6.01 US$22,237
2009-08-25 2009-08-24 PlS Planned sale SHAFFER CHRISTY L

President & CEO

Executive Director
2,900 -0.8%
6.02
US$17,458 		2,900 -0.8% 6.02 US$17,458
2009-08-25 2009-08-24 PlS Planned sale SHAFFER CHRISTY L

President & CEO

Executive Director
1,200 -0.3%
6.03
US$7,236 		1,200 -0.3% 6.03 US$7,236
2009-08-25 2009-08-24 PlS Planned sale SHAFFER CHRISTY L

President & CEO

Executive Director
400 -0.1%
6.04
US$2,416 		400 -0.1% 6.04 US$2,416
2009-08-10 2009-08-10 B Purchase Warburg Pincus Private Equity IX, L.P. Large shareholder
8,888,888 +63.4%
4.50
US$39,999,996 		8,888,888 +63.4% 4.50 US$39,999,996
2009-08-10 2009-08-10 B Purchase LEFF JONATHAN S Non-Executive Director
8,888,888 +63.4%
4.50
US$39,999,996 		8,888,888 +63.4% 4.50 US$39,999,996
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.1%
4.61
US$461 		100 -0.1% 4.61 US$461
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.1%
4.68
US$468 		100 -0.1% 4.68 US$468
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
4.71
US$942 		200 -0.3% 4.71 US$942
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
300 -0.4%
4.72
US$1,416 		300 -0.4% 4.72 US$1,416
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.1%
4.79
US$479 		100 -0.1% 4.79 US$479
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
478 -0.7%
4.82
US$2,304 		478 -0.7% 4.82 US$2,304
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
22 -0.0%
4.84
US$106 		22 -0.0% 4.84 US$106
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
4.88
US$976 		200 -0.3% 4.88 US$976
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
200 -0.3%
4.94
US$988 		200 -0.3% 4.94 US$988
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.1%
4.96
US$496 		100 -0.1% 4.96 US$496
2009-08-03 2009-08-03 PlS Planned sale YERXA BENJAMIN R

EVP & Chf, Research & Develop

Officer
100 -0.1%
5.00
US$500 		100 -0.1% 5.00 US$500
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