|
2020-05-01 |
2020-05-01 |
B
Purchase
|
Non-Executive Director
Large shareholder
|
5,102
-23.0%
317.77
US$3,257,057
|
5,102
-23.0%
|
317.77
|
US$3,257,057
|
|
|
2019-12-09 |
2019-12-05 |
B
Purchase
|
Avoro Capital Advisors LLC
Non-Executive Director
Large shareholder
|
4,280
-3.7%
36.91
US$3,768,196
|
4,280
-3.7%
|
36.91
|
US$3,768,196
|
|
|
2019-10-04 |
2019-10-03 |
B
Purchase
|
Large shareholder
|
14,941
+28.5%
448.86
US$3,717,310
|
14,941
+28.5%
|
448.86
|
US$3,717,310
|
|
|
2019-10-03 |
2019-10-03 |
B
Purchase
|
Chief Quality Officer
|
5,000
+100.0%
14.18
US$70,896
|
5,000
+100.0%
|
14.18
|
US$70,896
|
|
|
2019-10-04 |
2019-10-02 |
B
Purchase
|
Large shareholder
|
1,000,000
+4.8%
13.23
US$13,230,000
|
1,000,000
+4.8%
|
13.23
|
US$13,230,000
|
|
|
2019-06-28 |
2019-06-28 |
B
Purchase
|
Large shareholder
|
250,000
+1.2%
13.84
US$3,460,000
|
250,000
+1.2%
|
13.84
|
US$3,460,000
|
|
|
2019-06-28 |
2019-06-27 |
B
Purchase
|
Large shareholder
|
350,000
+1.7%
13.68
US$4,788,000
|
350,000
+1.7%
|
13.68
|
US$4,788,000
|
|
|
2019-06-28 |
2019-06-26 |
B
Purchase
|
Large shareholder
|
400,000
+2.0%
13.25
US$5,300,000
|
400,000
+2.0%
|
13.25
|
US$5,300,000
|
|
|
2019-06-21 |
2019-06-20 |
B
Purchase
|
Chief Quality Officer
|
5,000
+inf%
13.35
US$66,750
|
5,000
+inf%
|
13.35
|
US$66,750
|
|
|
2019-06-05 |
2019-06-05 |
B
Purchase
|
Large shareholder
|
250,000
+1.3%
12.47
US$3,117,500
|
250,000
+1.3%
|
12.47
|
US$3,117,500
|
|
|
2019-06-05 |
2019-06-04 |
B
Purchase
|
Large shareholder
|
500,000
+2.6%
12.10
US$6,050,000
|
500,000
+2.6%
|
12.10
|
US$6,050,000
|
|
|
2019-06-05 |
2019-06-03 |
B
Purchase
|
Large shareholder
|
785,539
+4.3%
12.19
US$9,575,720
|
785,539
+4.3%
|
12.19
|
US$9,575,720
|
|
|
2019-05-15 |
2019-05-15 |
B
Purchase
|
|
125,000
+0.7%
14.95
US$1,868,750
|
125,000
+0.7%
|
14.95
|
US$1,868,750
|
|
|
2019-05-15 |
2019-05-14 |
B
Purchase
|
|
125,000
+0.7%
15.40
US$1,925,000
|
125,000
+0.7%
|
15.40
|
US$1,925,000
|
|
|
2019-05-15 |
2019-05-13 |
B
Purchase
|
|
500,000
+2.8%
15.07
US$7,535,000
|
500,000
+2.8%
|
15.07
|
US$7,535,000
|
|
|
2018-06-19 |
2018-06-15 |
B
Purchase
|
venBio Select Advisor LLC
Non-Executive Director
Large shareholder
|
200,000
+1.1%
23.39
US$4,678,000
|
200,000
+1.1%
|
23.39
|
US$4,678,000
|
|
|
2018-06-15 |
2018-06-15 |
B
Purchase
|
venBio Select Advisor LLC
Non-Executive Director
Large shareholder
|
575,000
+3.4%
24.00
US$13,800,000
|
575,000
+3.4%
|
24.00
|
US$13,800,000
|
|
|
2018-03-12 |
2018-03-07 |
S
Sale
|
GOLDENBERG DAVID M
|
20,000
-0.4%
17.75
US$355,000
|
20,000
-0.4%
|
17.75
|
US$355,000
|
|
|
2018-03-12 |
2018-03-07 |
S
Sale
|
GOLDENBERG DAVID M
|
20,000
-0.4%
17.60
US$352,000
|
20,000
-0.4%
|
17.60
|
US$352,000
|
|
|
2018-03-12 |
2018-03-07 |
S
Sale
|
GOLDENBERG DAVID M
|
20,000
-1.1%
17.50
US$350,000
|
20,000
-1.1%
|
17.50
|
US$350,000
|
|
|
2018-03-12 |
2018-03-05 |
S
Sale
|
GOLDENBERG DAVID M
|
20,000
-0.4%
17.17
US$343,400
|
20,000
-0.4%
|
17.17
|
US$343,400
|
|
|
2018-03-12 |
2018-03-05 |
S
Sale
|
GOLDENBERG DAVID M
|
20,000
-0.4%
17.30
US$346,000
|
20,000
-0.4%
|
17.30
|
US$346,000
|
|
|
2018-03-12 |
2018-02-28 |
S
Sale
|
GOLDENBERG DAVID M
|
17,729
-0.3%
17.09
US$302,989
|
17,729
-0.3%
|
17.09
|
US$302,989
|
|
|
2017-11-21 |
2017-11-20 |
S
Sale
|
MARKISON BRIAN A
|
8,390
-8.5%
11.89
US$99,724
|
8,390
-8.5%
|
11.89
|
US$99,724
|
|
|
2017-11-16 |
2017-11-15 |
B
Purchase
|
venBio Select Advisor LLC
Large shareholder
|
175,000
+1.1%
10.97
US$1,919,750
|
175,000
+1.1%
|
10.97
|
US$1,919,750
|
|
|
2017-11-15 |
2017-11-15 |
B
Purchase
|
Aghazadeh Behzad
Large shareholder
|
175,000
+1.1%
10.97
US$1,919,750
|
175,000
+1.1%
|
10.97
|
US$1,919,750
|
|
|
2017-11-16 |
2017-11-14 |
B
Purchase
|
venBio Select Advisor LLC
Large shareholder
|
1,150,000
+7.8%
10.39
US$11,948,500
|
1,150,000
+7.8%
|
10.39
|
US$11,948,500
|
|
|
2017-11-15 |
2017-11-14 |
B
Purchase
|
Aghazadeh Behzad
Large shareholder
|
1,150,000
+7.8%
10.39
US$11,948,500
|
1,150,000
+7.8%
|
10.39
|
US$11,948,500
|
|
|
2017-09-05 |
2017-09-01 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
10,000
-1.3%
12.90
US$129,000
|
10,000
-1.3%
|
12.90
|
US$129,000
|
|
|
2017-09-05 |
2017-09-01 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
10,000
-0.3%
12.90
US$129,000
|
10,000
-0.3%
|
12.90
|
US$129,000
|
|
|
2017-09-05 |
2017-08-31 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
5,000
-0.6%
12.50
US$62,500
|
5,000
-0.6%
|
12.50
|
US$62,500
|
|
|
2017-09-05 |
2017-08-31 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
5,000
-0.6%
12.25
US$61,250
|
5,000
-0.6%
|
12.25
|
US$61,250
|
|
|
2017-09-05 |
2017-08-31 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
5,000
-0.1%
12.50
US$62,500
|
5,000
-0.1%
|
12.50
|
US$62,500
|
|
|
2017-09-05 |
2017-08-31 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
5,000
-0.1%
12.25
US$61,250
|
5,000
-0.1%
|
12.25
|
US$61,250
|
|
|
2017-08-28 |
2017-08-28 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
10,000
-0.3%
11.56
US$115,591
|
10,000
-0.3%
|
11.56
|
US$115,591
|
|
|
2017-08-28 |
2017-08-28 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
5,000
11.45
US$57,250
|
5,000
|
11.45
|
US$57,250
|
|
|
2017-08-28 |
2017-08-28 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
10,000
-1.2%
11.56
US$115,591
|
10,000
-1.2%
|
11.56
|
US$115,591
|
|
|
2017-08-28 |
2017-08-28 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
5,000
-0.6%
11.45
US$57,250
|
5,000
-0.6%
|
11.45
|
US$57,250
|
|
|
2017-08-28 |
2017-08-24 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
25,000
10.24
US$256,105
|
25,000
|
10.24
|
US$256,105
|
|
|
2017-08-28 |
2017-08-24 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
25,000
-3.0%
10.24
US$256,105
|
25,000
-3.0%
|
10.24
|
US$256,105
|
|
|
2017-08-23 |
2017-08-23 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
10,000
-0.3%
9.50
US$95,000
|
10,000
-0.3%
|
9.50
|
US$95,000
|
|
|
2017-08-23 |
2017-08-23 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
10,000
-1.2%
9.50
US$95,000
|
10,000
-1.2%
|
9.50
|
US$95,000
|
|
|
2017-08-23 |
2017-08-22 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
10,000
-0.3%
9.50
US$95,000
|
10,000
-0.3%
|
9.50
|
US$95,000
|
|
|
2017-08-23 |
2017-08-22 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
10,000
-1.2%
9.50
US$95,000
|
10,000
-1.2%
|
9.50
|
US$95,000
|
|
|
2017-08-23 |
2017-08-21 |
S
Sale
|
GOLDENBERG DAVID M
See Remarks
Executive Director
|
20,000
-0.6%
8.97
US$179,426
|
20,000
-0.6%
|
8.97
|
US$179,426
|
|
|
2017-08-23 |
2017-08-21 |
S
Sale
|
GOLDENBERG CYNTHIA L
|
20,000
-2.3%
8.97
US$179,426
|
20,000
-2.3%
|
8.97
|
US$179,426
|
|
|
2016-08-25 |
2016-08-24 |
S
Sale
|
Stark Don C
Non-Executive Director
|
9,900
-15.1%
2.97
US$29,451
|
9,900
-15.1%
|
2.97
|
US$29,451
|
|
|
2016-08-25 |
2016-08-23 |
S
Sale
|
PAETZOLD MARY E
Non-Executive Director
|
15,000
-18.2%
2.98
US$44,673
|
15,000
-18.2%
|
2.98
|
US$44,673
|
|
|
2016-08-25 |
2016-08-23 |
S
Sale
|
MARKISON BRIAN A
Non-Executive Director
|
15,000
-16.6%
2.98
US$44,634
|
15,000
-16.6%
|
2.98
|
US$44,634
|
|
|
2016-06-14 |
2016-06-13 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
128,674
-3.7%
3.02
US$389,200
|
128,674
-3.7%
|
3.02
|
US$389,200
|
|
|
2016-06-14 |
2016-06-13 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
139,950
-5.3%
3.02
US$422,621
|
139,950
-5.3%
|
3.02
|
US$422,621
|
|
|
2016-06-14 |
2016-06-13 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
139,950
-2.6%
3.02
US$422,621
|
139,950
-2.6%
|
3.02
|
US$422,621
|
|
|
2016-06-14 |
2016-06-13 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
128,674
-16.8%
3.02
US$389,200
|
128,674
-16.8%
|
3.02
|
US$389,200
|
|
|
2016-06-14 |
2016-06-10 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
11,326
-0.3%
3.07
US$34,781
|
11,326
-0.3%
|
3.07
|
US$34,781
|
|
|
2016-06-14 |
2016-06-10 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
92,040
-3.6%
3.05
US$281,155
|
92,040
-3.6%
|
3.05
|
US$281,155
|
|
|
2016-06-14 |
2016-06-10 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
92,040
-1.7%
3.05
US$281,155
|
92,040
-1.7%
|
3.05
|
US$281,155
|
|
|
2016-06-14 |
2016-06-10 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
11,326
-1.7%
3.07
US$34,781
|
11,326
-1.7%
|
3.07
|
US$34,781
|
|
|
2016-06-08 |
2016-06-08 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
41,441
-1.2%
3.62
US$150,219
|
41,441
-1.2%
|
3.62
|
US$150,219
|
|
|
2016-06-08 |
2016-06-08 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
120,388
-4.6%
3.64
US$438,778
|
120,388
-4.6%
|
3.64
|
US$438,778
|
|
|
2016-06-08 |
2016-06-08 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
120,388
-2.2%
3.64
US$438,778
|
120,388
-2.2%
|
3.64
|
US$438,778
|
|
|
2016-06-08 |
2016-06-08 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
41,441
-6.1%
3.62
US$150,219
|
41,441
-6.1%
|
3.62
|
US$150,219
|
|
|
2016-06-08 |
2016-06-07 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
4,600
-0.1%
4.01
US$18,427
|
4,600
-0.1%
|
4.01
|
US$18,427
|
|
|
2016-06-08 |
2016-06-07 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
12,300
-0.5%
3.98
US$48,954
|
12,300
-0.5%
|
3.98
|
US$48,954
|
|
|
2016-06-08 |
2016-06-07 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
12,300
-0.2%
3.98
US$48,954
|
12,300
-0.2%
|
3.98
|
US$48,954
|
|
|
2016-06-08 |
2016-06-07 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
4,600
-0.7%
4.01
US$18,427
|
4,600
-0.7%
|
4.01
|
US$18,427
|
|
|
2016-06-08 |
2016-06-06 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
63,959
-1.9%
4.09
US$261,880
|
63,959
-1.9%
|
4.09
|
US$261,880
|
|
|
2016-06-08 |
2016-06-06 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
110,322
-4.2%
4.09
US$451,007
|
110,322
-4.2%
|
4.09
|
US$451,007
|
|
|
2016-06-08 |
2016-06-06 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
110,322
-2.1%
4.09
US$451,007
|
110,322
-2.1%
|
4.09
|
US$451,007
|
|
|
2016-06-08 |
2016-06-06 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
63,959
-9.1%
4.09
US$261,880
|
63,959
-9.1%
|
4.09
|
US$261,880
|
|
|
2015-12-04 |
2015-12-01 |
S
Sale
|
Stark Don C
Non-Executive Director
|
5,100
-10.1%
3.16
US$16,090
|
5,100
-10.1%
|
3.16
|
US$16,090
|
|
|
2015-06-16 |
2015-06-15 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
90,666
-1.7%
4.07
US$368,920
|
90,666
-1.7%
|
4.07
|
US$368,920
|
|
|
2015-06-16 |
2015-06-15 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
82,077
-1.5%
4.07
US$333,971
|
82,077
-1.5%
|
4.07
|
US$333,971
|
|
|
2015-06-16 |
2015-06-15 |
S
Sale
|
GOLDENBERG CYNTHIA L
President and CEO
Executive Director
|
38,248
-6.6%
4.12
US$157,677
|
38,248
-6.6%
|
4.12
|
US$157,677
|
|
|
2015-06-16 |
2015-06-15 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
38,248
-1.2%
4.12
US$157,677
|
38,248
-1.2%
|
4.12
|
US$157,677
|
|
|
2015-06-16 |
2015-06-15 |
S
Sale
|
GOLDENBERG DAVID M
CSO & Chairman of the BOD
Executive Director
|
90,666
-3.3%
4.07
US$368,920
|
90,666
-3.3%
|
4.07
|
US$368,920
|
|