|
2006-06-13 |
2006-06-13 |
B
Purchase
|
BLUM LEONARD M
Sr. VP, Sales and Mktg
Officer
|
82,367
-48.9%
133.38
US$881,665
|
82,367
-48.9%
|
133.38
|
US$881,665
|
|
|
2006-06-13 |
2006-06-13 |
B
Purchase
|
BLUM LEONARD M
Sr. VP, Sales and Mktg
Officer
|
46,171
+31.7%
311.87
US$2,218,409
|
46,171
+31.7%
|
311.87
|
US$2,218,409
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
55,428
-32.9%
212.70
US$4,163,874
|
55,428
-32.9%
|
212.70
|
US$4,163,874
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
558
-0.5%
21.58
US$12,042
|
558
-0.5%
|
21.58
|
US$12,042
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
558
-0.5%
21.89
US$12,215
|
558
-0.5%
|
21.89
|
US$12,215
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
563
-0.5%
21.86
US$12,308
|
563
-0.5%
|
21.86
|
US$12,308
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
558
-0.5%
21.70
US$12,109
|
558
-0.5%
|
21.70
|
US$12,109
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
1,116
-0.9%
21.68
US$24,196
|
1,116
-0.9%
|
21.68
|
US$24,196
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
558
-0.4%
21.66
US$12,087
|
558
-0.4%
|
21.66
|
US$12,087
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
558
-0.4%
21.52
US$12,009
|
558
-0.4%
|
21.52
|
US$12,009
|
|
|
2006-05-02 |
2006-05-01 |
PlS
Planned sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
558
-0.4%
21.50
US$11,998
|
558
-0.4%
|
21.50
|
US$11,998
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
778
-4.5%
23.29
US$18,121
|
778
-4.5%
|
23.29
|
US$18,121
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-5.5%
23.33
US$23,332
|
1,000
-5.5%
|
23.33
|
US$23,332
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-5.2%
23.36
US$23,359
|
1,000
-5.2%
|
23.36
|
US$23,359
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-4.9%
23.37
US$23,367
|
1,000
-4.9%
|
23.37
|
US$23,367
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-4.7%
23.40
US$23,396
|
1,000
-4.7%
|
23.40
|
US$23,396
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-4.5%
23.40
US$23,401
|
1,000
-4.5%
|
23.40
|
US$23,401
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-4.3%
23.43
US$23,427
|
1,000
-4.3%
|
23.43
|
US$23,427
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-4.1%
23.46
US$23,459
|
1,000
-4.1%
|
23.46
|
US$23,459
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-4.0%
23.50
US$23,503
|
1,000
-4.0%
|
23.50
|
US$23,503
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.8%
23.51
US$23,507
|
1,000
-3.8%
|
23.51
|
US$23,507
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.7%
23.50
US$23,504
|
1,000
-3.7%
|
23.50
|
US$23,504
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.5%
23.51
US$23,512
|
1,000
-3.5%
|
23.51
|
US$23,512
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.4%
23.47
US$23,473
|
1,000
-3.4%
|
23.47
|
US$23,473
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.3%
23.47
US$23,471
|
1,000
-3.3%
|
23.47
|
US$23,471
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.2%
23.50
US$23,500
|
1,000
-3.2%
|
23.50
|
US$23,500
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.1%
23.49
US$23,490
|
1,000
-3.1%
|
23.49
|
US$23,490
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-3.0%
23.49
US$23,485
|
1,000
-3.0%
|
23.49
|
US$23,485
|
|
|
2006-03-20 |
2006-03-16 |
S
Sale
|
FERGUSON JAMES L
Non-Executive Director
|
1,000
-2.9%
23.52
US$23,520
|
1,000
-2.9%
|
23.52
|
US$23,520
|
|
|
2006-02-23 |
2006-02-23 |
S
Sale
|
PANGIA ROBERT W
Non-Executive Director
|
2,778
-100.0%
24.55
US$68,193
|
2,778
-100.0%
|
24.55
|
US$68,193
|
|
|
2006-02-23 |
2006-02-23 |
S
Sale
|
PANGIA ROBERT W
Non-Executive Director
|
2,500
-47.4%
24.54
US$61,350
|
2,500
-47.4%
|
24.54
|
US$61,350
|
|
|
2006-02-23 |
2006-02-23 |
S
Sale
|
PANGIA ROBERT W
Non-Executive Director
|
2,500
-32.1%
24.51
US$61,280
|
2,500
-32.1%
|
24.51
|
US$61,280
|
|
|
2006-02-23 |
2006-02-23 |
S
Sale
|
PANGIA ROBERT W
Non-Executive Director
|
10,000
-56.2%
24.50
US$245,000
|
10,000
-56.2%
|
24.50
|
US$245,000
|
|
|
2006-01-03 |
2005-12-29 |
B
Purchase
|
BLUM LEONARD M
Sr. VP, Sales and Mktg
Officer
|
1,000
+1.4%
27.97
US$27,970
|
1,000
+1.4%
|
27.97
|
US$27,970
|
|
|
2005-12-13 |
2005-12-13 |
S
Sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
6,773
-5.7%
27.75
US$187,951
|
6,773
-5.7%
|
27.75
|
US$187,951
|
|
|
2005-12-13 |
2005-12-13 |
S
Sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
100
-0.1%
27.76
US$2,776
|
100
-0.1%
|
27.76
|
US$2,776
|
|
|
2005-12-13 |
2005-12-13 |
S
Sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
240
-0.2%
28.00
US$6,720
|
240
-0.2%
|
28.00
|
US$6,720
|
|
|
2005-12-08 |
2005-12-08 |
S
Sale
|
ST JOHN THOMAS P
VP, Therapeutic Development
Officer
|
7,114
-6.0%
28.00
US$199,192
|
7,114
-6.0%
|
28.00
|
US$199,192
|
|
|
2005-11-30 |
2005-11-29 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
4,217
-13.8%
27.80
US$117,233
|
4,217
-13.8%
|
27.80
|
US$117,233
|
|
|
2005-11-30 |
2005-11-29 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
3
-0.0%
27.81
US$83
|
3
-0.0%
|
27.81
|
US$83
|
|
|
2005-11-30 |
2005-11-29 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
18,989
-38.3%
28.00
US$531,692
|
18,989
-38.3%
|
28.00
|
US$531,692
|
|
|
2005-11-30 |
2005-11-29 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
891
-1.8%
28.15
US$25,082
|
891
-1.8%
|
28.15
|
US$25,082
|
|
|
2005-11-30 |
2005-11-29 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
500
-1.0%
28.17
US$14,085
|
500
-1.0%
|
28.17
|
US$14,085
|
|
|
2005-11-30 |
2005-11-29 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
1,300
-2.5%
28.18
US$36,634
|
1,300
-2.5%
|
28.18
|
US$36,634
|
|
|
2005-11-30 |
2005-11-29 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
100
-0.2%
28.19
US$2,819
|
100
-0.2%
|
28.19
|
US$2,819
|
|
|
2005-11-28 |
2005-11-28 |
B
Purchase
|
BECK TERESA
Non-Executive Director
|
3,540
+inf%
28.17
US$99,722
|
3,540
+inf%
|
28.17
|
US$99,722
|
|
|
2005-06-28 |
2005-06-27 |
S
Sale
|
MILLIGAN DAVID V
Non-Executive Director
|
2,339
-95.9%
21.32
US$49,867
|
2,339
-95.9%
|
21.32
|
US$49,867
|
|
|
2005-06-28 |
2005-06-27 |
S
Sale
|
MILLIGAN DAVID V
Non-Executive Director
|
3,000
-55.2%
21.27
US$63,810
|
3,000
-55.2%
|
21.27
|
US$63,810
|
|
|
2005-06-28 |
2005-06-27 |
S
Sale
|
MILLIGAN DAVID V
Non-Executive Director
|
2,500
-31.5%
21.30
US$53,250
|
2,500
-31.5%
|
21.30
|
US$53,250
|
|
|
2005-06-28 |
2005-06-27 |
S
Sale
|
MILLIGAN DAVID V
Non-Executive Director
|
12,500
-61.2%
21.22
US$265,250
|
12,500
-61.2%
|
21.22
|
US$265,250
|
|
|
2005-04-04 |
2005-03-31 |
B
Purchase
|
BRYSON VAUGHN D
Non-Executive Director
|
5,000
+inf%
22.54
US$112,704
|
5,000
+inf%
|
22.54
|
US$112,704
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
100
-0.2%
23.31
US$2,331
|
100
-0.2%
|
23.31
|
US$2,331
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
5,000
-8.7%
23.30
US$116,500
|
5,000
-8.7%
|
23.30
|
US$116,500
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
500
-0.9%
23.28
US$11,640
|
500
-0.9%
|
23.28
|
US$11,640
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
857
-1.5%
23.27
US$19,942
|
857
-1.5%
|
23.27
|
US$19,942
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
987
-1.6%
23.20
US$22,898
|
987
-1.6%
|
23.20
|
US$22,898
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
13,587
-18.5%
23.19
US$315,083
|
13,587
-18.5%
|
23.19
|
US$315,083
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
14,100
-16.1%
23.18
US$326,838
|
14,100
-16.1%
|
23.18
|
US$326,838
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
1,600
-1.8%
23.17
US$37,072
|
1,600
-1.8%
|
23.17
|
US$37,072
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
5,169
-5.5%
23.16
US$119,714
|
5,169
-5.5%
|
23.16
|
US$119,714
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
600
-0.6%
23.15
US$13,890
|
600
-0.6%
|
23.15
|
US$13,890
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
600
-0.6%
23.14
US$13,884
|
600
-0.6%
|
23.14
|
US$13,884
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
900
-0.9%
23.13
US$20,817
|
900
-0.9%
|
23.13
|
US$20,817
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
1,100
-1.1%
23.12
US$25,432
|
1,100
-1.1%
|
23.12
|
US$25,432
|
|
|
2005-02-22 |
2005-02-22 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
4,900
-4.8%
23.11
US$113,239
|
4,900
-4.8%
|
23.11
|
US$113,239
|
|
|
2005-02-15 |
2005-02-14 |
S
Sale
|
PANGIA ROBERT W
Non-Executive Director
|
5,000
-100.0%
23.03
US$115,156
|
5,000
-100.0%
|
23.03
|
US$115,156
|
|
|
2005-02-15 |
2005-02-14 |
S
Sale
|
PANGIA ROBERT W
Non-Executive Director
|
23,108
-82.2%
23.00
US$531,484
|
23,108
-82.2%
|
23.00
|
US$531,484
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
516
-0.5%
27.05
US$13,958
|
516
-0.5%
|
27.05
|
US$13,958
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
200
-0.2%
27.04
US$5,408
|
200
-0.2%
|
27.04
|
US$5,408
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
200
-0.2%
27.03
US$5,406
|
200
-0.2%
|
27.03
|
US$5,406
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
200
-0.2%
27.01
US$5,402
|
200
-0.2%
|
27.01
|
US$5,402
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
3,233
-3.0%
27.00
US$87,291
|
3,233
-3.0%
|
27.00
|
US$87,291
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
2,362
-2.2%
26.95
US$63,656
|
2,362
-2.2%
|
26.95
|
US$63,656
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
510
-0.5%
26.93
US$13,734
|
510
-0.5%
|
26.93
|
US$13,734
|
|
|
2005-01-12 |
2005-01-10 |
S
Sale
|
CARY FRANK T
Non-Executive Director
|
100
-0.1%
26.92
US$2,692
|
100
-0.1%
|
26.92
|
US$2,692
|
|