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United States Biotechnology & Medical Research

Entrada Therapeutics Inc (TRDA)

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Over the last 90 days, Entrada Therapeutics Inc. has seen a net sale of insider shares totaling $1,285,839.27, with a single insider purchase of $29,316.00. Notably, several executives, including the President & COO and CFO, have engaged in planned and proposed sales. The stock has experienced a significant price decrease of 49.3% in the same period.
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Ticker: TRDA Exchange: NMS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
Zeiher Bernhardt G
1 purchase — total 29,316 USD
Buy 20 May 2026
Value US$2,139,970.82 | Price 281.07 | Shares 29,710
Planned sale 4 May 2026
Value US$755,304.40 | Price 229.92 | Shares 81,529
Planned sale 4 May 2026
Value US$229,953.00 | Price 15.33 | Shares 15,000
Proposed sale 4 May 2026
Value US$217,500.00 | Price 14.50 | Shares 15,000
Proposed sale 4 May 2026
Value US$375,651.50 | Price 14.50 | Shares 25,907
Planned sale 1 Apr 2026
Value US$32,375.00 | Price 12.95 | Shares 2,500
Proposed sale 1 Apr 2026
Value US$31,550.00 | Price 12.62 | Shares 2,500
Planned sale 10 Mar 2026
Value US$155,188.15 | Price 13.05 | Shares 11,894
Planned sale 10 Mar 2026
Value US$148,215.96 | Price 13.02 | Shares 11,388
Planned sale 9 Mar 2026
Value US$40,582.78 | Price 13.02 | Shares 3,116
Planned sale 9 Mar 2026
Value US$66,162.60 | Price 13.00 | Shares 5,089
Proposed sale 9 Mar 2026
Value US$207,280.66 | Price 12.58 | Shares 16,477
Proposed sale 9 Mar 2026
Value US$188,825.80 | Price 12.58 | Shares 15,010
Planned sale 4 Mar 2026
Value US$97,892.14 | Price 12.25 | Shares 7,988
Proposed sale 4 Mar 2026
Value US$94,657.80 | Price 11.85 | Shares 7,988
Planned sale 21 Nov 2025
Value US$88,931.60 | Price 9.98 | Shares 8,910
Proposed sale 21 Nov 2025
Value US$81,704.70 | Price 9.17 | Shares 8,910
Buy 20 Nov 2025
Value US$118,690.37 | Price 9.07 | Shares 13,082
Buy 20 Nov 2025
Value US$10,760.34 | Price 9.07 | Shares 1,186
Buy 20 Nov 2025
Value US$121,394.96 | Price 9.07 | Shares 13,386
Buy 20 Nov 2025
Value US$11,000.45 | Price 9.07 | Shares 1,213
Sale 14 Nov 2025
Value US$1,760,000.00 | Price 8.80 | Shares 200,000
Proposed sale 14 Nov 2025
Value US$1,760,664.00 | Price 8.80 | Shares 200,000
Sale 14 Nov 2025
Value US$1,760,000.00 | Price 8.80 | Shares 200,000
Buy 12 Nov 2025
Value US$91,431.32 | Price 7.95 | Shares 11,494
Buy 12 Nov 2025
Value US$8,272.89 | Price 7.95 | Shares 1,040
Buy 12 Nov 2025
Value US$625,331.45 | Price 7.73 | Shares 80,881
Buy 12 Nov 2025
Value US$56,602.31 | Price 7.73 | Shares 7,321
Buy 11 Nov 2025
Value US$232,812.22 | Price 7.54 | Shares 30,879
Buy 11 Nov 2025
Value US$21,072.90 | Price 7.54 | Shares 2,795
Buy 11 Nov 2025
Value US$86,480.92 | Price 7.39 | Shares 11,701
Buy 11 Nov 2025
Value US$7,826.96 | Price 7.39 | Shares 1,059
Buy 10 Nov 2025
Value US$21,290.31 | Price 7.22 | Shares 2,947
Buy 10 Nov 2025
Value US$1,928.91 | Price 7.22 | Shares 267
Buy 10 Nov 2025
Value US$182,973.36 | Price 7.21 | Shares 25,364
Buy 10 Nov 2025
Value US$16,563.11 | Price 7.21 | Shares 2,296
Sale 9 Jul 2025
Value US$52,026.37 | Price 7.50 | Shares 6,935
Sale 9 Jul 2025
Value US$150,527.63 | Price 7.50 | Shares 20,065
Proposed sale 9 Jul 2025
Value US$150,527.63 | Price 7.50 | Shares 20,065
Sale 9 Jul 2025
Value US$52,026.37 | Price 7.50 | Shares 6,935
Sale 9 Jul 2025
Value US$150,527.63 | Price 7.50 | Shares 20,065
Proposed sale 9 Jul 2025
Value US$52,025.37 | Price 7.50 | Shares 6,935
Proposed sale 1 Jul 2025
Value US$132,323.66 | Price 7.12 | Shares 18,578
Sale 1 Jul 2025
Value US$45,741.34 | Price 7.12 | Shares 6,422
Sale 1 Jul 2025
Value US$132,323.66 | Price 7.12 | Shares 18,578
Proposed sale 1 Jul 2025
Value US$45,737.48 | Price 7.12 | Shares 6,422
Sale 1 Jul 2025
Value US$45,741.34 | Price 7.12 | Shares 6,422
Sale 1 Jul 2025
Value US$132,323.66 | Price 7.12 | Shares 18,578
Sale 30 Jun 2025
Value US$43,751.16 | Price 6.81 | Shares 6,422
Sale 30 Jun 2025
Value US$126,566.34 | Price 6.81 | Shares 18,578
Sale 30 Jun 2025
Value US$43,751.16 | Price 6.81 | Shares 6,422
Sale 30 Jun 2025
Value US$126,566.34 | Price 6.81 | Shares 18,578
Sale 27 Jun 2025
Value US$133,121.15 | Price 6.91 | Shares 19,265
Sale 27 Jun 2025
Value US$385,128.85 | Price 6.91 | Shares 55,735
Sale 27 Jun 2025
Value US$133,121.15 | Price 6.91 | Shares 19,265
Sale 27 Jun 2025
Value US$385,128.85 | Price 6.91 | Shares 55,735
Proposed sale 27 Jun 2025
Value US$385,128.85 | Price 6.91 | Shares 55,735
Proposed sale 27 Jun 2025
Value US$133,121.15 | Price 6.91 | Shares 19,265
Planned sale 17 Mar 2025
Value US$19,035.28 | Price 10.67 | Shares 1,784
Proposed sale 17 Mar 2025
Value US$19,285.04 | Price 10.81 | Shares 1,784
Sale 11 Dec 2024
Value US$440,751.01 | Price 20.23 | Shares 21,787
Sale 11 Dec 2024
Value US$440,751.01 | Price 20.23 | Shares 21,787
Sale 10 Dec 2024
Value US$476,359.95 | Price 20.77 | Shares 22,935
Sale 10 Dec 2024
Value US$476,359.95 | Price 20.77 | Shares 22,935
Planned sale 3 Dec 2024
Value US$235,786.19 | Price 20.15 | Shares 11,703
Planned sale 2 Dec 2024
Value US$82,833.51 | Price 20.26 | Shares 4,088
Planned sale 2 Dec 2024
Value US$99,978.00 | Price 20.00 | Shares 5,000
Planned sale 29 Nov 2024
Value US$2,000.00 | Price 20.00 | Shares 100
Planned sale 29 Nov 2024
Value US$19,970.30 | Price 19.97 | Shares 1,000
Planned sale 13 Nov 2024
Value US$54,108.81 | Price 20.04 | Shares 2,700
Planned sale 11 Nov 2024
Value US$28,191.13 | Price 20.01 | Shares 1,409
Planned sale 11 Nov 2024
Value US$172,562.08 | Price 19.98 | Shares 8,637
Proposed sale 11 Nov 2024
Value US$371,862.84 | Price 19.82 | Shares 18,762
Proposed sale 11 Nov 2024
Value US$290,105.34 | Price 19.82 | Shares 14,637
Planned sale 6 Nov 2024
Value US$53,023.52 | Price 19.32 | Shares 2,745
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-05-21 2026-05-20 B Purchase
3.3
Zeiher Bernhardt G
Non-Executive Director
29,710 +11.7%
281.07
US$2,139,971 		29,710 +11.7% 281.07 US$2,139,971
2026-05-04 2026-05-04 PlS Planned sale
Sethuraman Natarajan

President, Research & Develop.

Officer
81,529 -17.1%
229.92
US$755,304 		81,529 -17.1% 229.92 US$755,304
2026-05-04 2026-05-04 PlS Planned sale
Dowden Nathan J

President & COO

Officer
51,621 -39.9%
39.47
US$4,691,061 		51,621 -39.9% 39.47 US$4,691,061
2026-05-04 2026-05-04 PrS Proposed sale
NATHAN DOWDEN

Officer

Officer
15,000
14.50
US$217,500 		15,000 14.50 US$217,500
2026-05-04 2026-05-04 PrS Proposed sale
NATARAJAN SETHURAMAN

Officer

Officer
25,907
14.50
US$375,652 		25,907 14.50 US$375,652
2026-04-02 2026-04-01 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
2,500 -2.1%
12.95
US$32,375 		2,500 -2.1% 12.95 US$32,375
2026-04-01 2026-04-01 PrS Proposed sale
3.4
KORY WENTWORTH

Officer

Officer
2,500
12.62
US$31,550 		2,500 12.62 US$31,550
2026-03-11 2026-03-10 PlS Planned sale
Dowden Nathan J

President & COO

Officer
11,894 -5.7%
13.05
US$155,188 		11,894 -5.7% 13.05 US$155,188
2026-03-11 2026-03-10 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
11,388 -8.6%
13.02
US$148,216 		11,388 -8.6% 13.02 US$148,216
2026-03-11 2026-03-09 PlS Planned sale
Dowden Nathan J

President & COO

Officer
3,116 -1.5%
13.02
US$40,583 		3,116 -1.5% 13.02 US$40,583
2026-03-11 2026-03-09 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
5,089 -3.7%
13.00
US$66,163 		5,089 -3.7% 13.00 US$66,163
2026-03-09 2026-03-09 PrS Proposed sale
3.4
KORY WENTWORTH

Officer

Officer
16,477
12.58
US$207,281 		16,477 12.58 US$207,281
2026-03-09 2026-03-09 PrS Proposed sale
NATHAN DOWDEN

Officer

Officer
15,010
12.58
US$188,826 		15,010 12.58 US$188,826
2026-03-06 2026-03-04 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
7,988 -5.5%
12.25
US$97,892 		7,988 -5.5% 12.25 US$97,892
2026-03-04 2026-03-04 PrS Proposed sale
3.4
KORY WENTWORTH

Officer

Officer
7,988
11.85
US$94,658 		7,988 11.85 US$94,658
2025-11-24 2025-11-21 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
8,910 -7.5%
9.98
US$88,932 		8,910 -7.5% 9.98 US$88,932
2025-11-21 2025-11-21 PrS Proposed sale
3.4
KORY WENTWORTH

Officer

Officer
8,910
9.17
US$81,705 		8,910 9.17 US$81,705
2025-11-24 2025-11-20 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
13,082 +0.3%
9.07
US$118,690 		13,082 +0.3% 9.07 US$118,690
2025-11-24 2025-11-20 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
1,186 +0.3%
9.07
US$10,760 		1,186 +0.3% 9.07 US$10,760
2025-11-24 2025-11-20 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
13,386 +0.3%
9.07
US$121,395 		13,386 +0.3% 9.07 US$121,395
2025-11-24 2025-11-20 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
1,213 +0.3%
9.07
US$11,000 		1,213 +0.3% 9.07 US$11,000
2025-11-18 2025-11-14 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
200,000 -6.3%
8.80
US$1,760,000 		200,000 -6.3% 8.80 US$1,760,000
2025-11-18 2025-11-14 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
200,000 -6.3%
8.80
US$1,760,000 		200,000 -6.3% 8.80 US$1,760,000
2025-11-14 2025-11-14 PrS Proposed sale
3.5
5AM Ventures V, L.P.

Affiliated Stockholder

Large shareholder
200,000
8.80
US$1,760,664 		200,000 8.80 US$1,760,664
2025-11-12 2025-11-12 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
11,494 +0.2%
7.95
US$91,431 		11,494 +0.2% 7.95 US$91,431
2025-11-12 2025-11-12 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
1,040 +0.3%
7.95
US$8,273 		1,040 +0.3% 7.95 US$8,273
2025-11-12 2025-11-12 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
80,881 +1.8%
7.73
US$625,331 		80,881 +1.8% 7.73 US$625,331
2025-11-12 2025-11-12 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
7,321 +2.0%
7.73
US$56,602 		7,321 +2.0% 7.73 US$56,602
2025-11-12 2025-11-11 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
30,879 +0.7%
7.54
US$232,812 		30,879 +0.7% 7.54 US$232,812
2025-11-12 2025-11-11 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
2,795 +0.8%
7.54
US$21,073 		2,795 +0.8% 7.54 US$21,073
2025-11-12 2025-11-11 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
11,701 +0.3%
7.39
US$86,481 		11,701 +0.3% 7.39 US$86,481
2025-11-12 2025-11-11 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
1,059 +0.3%
7.39
US$7,827 		1,059 +0.3% 7.39 US$7,827
2025-11-12 2025-11-10 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
2,947 +0.1%
7.22
US$21,290 		2,947 +0.1% 7.22 US$21,290
2025-11-12 2025-11-10 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
267 +0.1%
7.22
US$1,929 		267 +0.1% 7.22 US$1,929
2025-11-12 2025-11-10 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
25,364 +0.6%
7.21
US$182,973 		25,364 +0.6% 7.21 US$182,973
2025-11-12 2025-11-10 B Purchase
3.9
BAKER BROS. ADVISORS LP
Large shareholder
2,296 +0.6%
7.21
US$16,563 		2,296 +0.6% 7.21 US$16,563
2025-07-11 2025-07-09 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
6,935 -0.6%
7.50
US$52,026 		6,935 -0.6% 7.50 US$52,026
2025-07-11 2025-07-09 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
20,065 -0.6%
7.50
US$150,528 		20,065 -0.6% 7.50 US$150,528
2025-07-11 2025-07-09 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
6,935 -0.6%
7.50
US$52,026 		6,935 -0.6% 7.50 US$52,026
2025-07-11 2025-07-09 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
20,065 -0.6%
7.50
US$150,528 		20,065 -0.6% 7.50 US$150,528
2025-07-09 2025-07-09 PrS Proposed sale
3.6
5AM Opportunities I, L.P.

Director

Non-Executive Director
6,935
7.50
US$52,025 		6,935 7.50 US$52,025
2025-07-09 2025-07-09 PrS Proposed sale
3.5
5AM Ventures V, L.P.

Director

Non-Executive Director
20,065
7.50
US$150,528 		20,065 7.50 US$150,528
2025-07-01 2025-07-01 PrS Proposed sale
3.5
5AM Ventures V, L.P.

Director

Non-Executive Director
18,578
7.12
US$132,324 		18,578 7.12 US$132,324
2025-07-01 2025-07-01 PrS Proposed sale
3.6
5AM Opportunities I, L.P.

Director

Non-Executive Director
6,422
7.12
US$45,737 		6,422 7.12 US$45,737
2025-07-01 2025-07-01 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
6,422 -0.6%
7.12
US$45,741 		6,422 -0.6% 7.12 US$45,741
2025-07-01 2025-07-01 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
18,578 -0.6%
7.12
US$132,324 		18,578 -0.6% 7.12 US$132,324
2025-07-01 2025-07-01 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
6,422 -0.6%
7.12
US$45,741 		6,422 -0.6% 7.12 US$45,741
2025-07-01 2025-07-01 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
18,578 -0.6%
7.12
US$132,324 		18,578 -0.6% 7.12 US$132,324
2025-07-01 2025-06-30 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
6,422 -0.6%
6.81
US$43,751 		6,422 -0.6% 6.81 US$43,751
2025-07-01 2025-06-30 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
18,578 -0.6%
6.81
US$126,566 		18,578 -0.6% 6.81 US$126,566
2025-07-01 2025-06-30 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
6,422 -0.6%
6.81
US$43,751 		6,422 -0.6% 6.81 US$43,751
2025-07-01 2025-06-30 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
18,578 -0.6%
6.81
US$126,566 		18,578 -0.6% 6.81 US$126,566
2025-07-01 2025-06-27 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
19,265 -1.7%
6.91
US$133,121 		19,265 -1.7% 6.91 US$133,121
2025-07-01 2025-06-27 S Sale
4.0
PARMAR KUSH
Non-Executive Director Large shareholder
55,735 -1.7%
6.91
US$385,129 		55,735 -1.7% 6.91 US$385,129
2025-07-01 2025-06-27 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
19,265 -1.7%
6.91
US$133,121 		19,265 -1.7% 6.91 US$133,121
2025-07-01 2025-06-27 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
55,735 -1.7%
6.91
US$385,129 		55,735 -1.7% 6.91 US$385,129
2025-06-27 2025-06-27 PrS Proposed sale
3.6
5AM Opportunities I, L.P.

Director

Non-Executive Director
19,265
6.91
US$133,121 		19,265 6.91 US$133,121
2025-06-27 2025-06-27 PrS Proposed sale
3.5
5AM Ventures V, L.P.

Director

Non-Executive Director
55,735
6.91
US$385,129 		55,735 6.91 US$385,129
2025-03-19 2025-03-17 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
1,784 -1.6%
10.67
US$19,035 		1,784 -1.6% 10.67 US$19,035
2025-03-17 2025-03-17 PrS Proposed sale
3.4
KORY WENTWORTH

Officer

Officer
1,784
10.81
US$19,285 		1,784 10.81 US$19,285
2024-12-12 2024-12-11 S Sale
3.2
MPM BioVentures 2014, L.P.
Large shareholder
21,787 -0.5%
20.23
US$440,751 		21,787 -0.5% 20.23 US$440,751
2024-12-12 2024-12-11 S Sale
3.3
MPM BIOVENTURES 2018, L.P.
Large shareholder
21,787 -0.5%
20.23
US$440,751 		21,787 -0.5% 20.23 US$440,751
2024-12-12 2024-12-10 S Sale
3.2
MPM BioVentures 2014, L.P.
Large shareholder
22,935 -0.5%
20.77
US$476,360 		22,935 -0.5% 20.77 US$476,360
2024-12-12 2024-12-10 S Sale
3.3
MPM BIOVENTURES 2018, L.P.
Large shareholder
22,935 -0.5%
20.77
US$476,360 		22,935 -0.5% 20.77 US$476,360
2024-12-03 2024-12-03 PlS Planned sale
Sethuraman Natarajan

President, Research & Develop.

Officer
11,703 -7.5%
20.15
US$235,786 		11,703 -7.5% 20.15 US$235,786
2024-12-03 2024-12-02 PlS Planned sale
Sethuraman Natarajan

President, Research & Develop.

Officer
4,088 -2.5%
20.26
US$82,834 		4,088 -2.5% 20.26 US$82,834
2024-12-03 2024-12-02 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
5,000 -6.3%
20.00
US$99,978 		5,000 -6.3% 20.00 US$99,978
2024-12-03 2024-11-29 PlS Planned sale
Sethuraman Natarajan

President, Research & Develop.

Officer
100 -0.1%
20.00
US$2,000 		100 -0.1% 20.00 US$2,000
2024-12-03 2024-11-29 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
1,000 -1.3%
19.97
US$19,970 		1,000 -1.3% 19.97 US$19,970
2024-11-13 2024-11-13 PlS Planned sale
Sethuraman Natarajan

President, Research & Develop.

Officer
2,700 -1.7%
20.04
US$54,109 		2,700 -1.7% 20.04 US$54,109
2024-11-13 2024-11-11 PlS Planned sale
Sethuraman Natarajan

President, Research & Develop.

Officer
1,409 -0.9%
20.01
US$28,191 		1,409 -0.9% 20.01 US$28,191
2024-11-13 2024-11-11 PlS Planned sale
3.4
WENTWORTH KORY JAMES

Chief Financial Officer

Officer
8,637 -10.5%
19.98
US$172,562 		8,637 -10.5% 19.98 US$172,562
2024-11-12 2024-11-11 PrS Proposed sale
NATARAJAN SETHURAMAN

Officer

Officer
18,762
19.82
US$371,863 		18,762 19.82 US$371,863
2024-11-12 2024-11-11 PrS Proposed sale
3.4
KORY WENTWORTH

Officer

Officer
14,637
19.82
US$290,105 		14,637 19.82 US$290,105
2024-11-06 2024-11-06 PlS Planned sale
Sethuraman Natarajan

President, Research & Develop.

Officer
2,745 -1.6%
19.32
US$53,024 		2,745 -1.6% 19.32 US$53,024
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