United States Biotechnology & Medical Research

Enanta Pharmaceuticals Inc (ENTA)

Track

Enanta Pharmaceuticals experienced significant insider trading activity on December 5, 2025, involving multiple executives selling shares. Key personnel, including the CEO and various officers, executed these disposals. Prior to this, smaller sales occurred on December 2, 2025. These recent transactions represent the primary movement of equity by company leadership within the observed timeframe.
Ticker: ENTA Exchange: NSM
Preparing chart...
Download chart Copy chart image Copy link Share to X Share


• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
Upgrade for signal details

Upgrade to see score, net flow, insiders and context.

Upgrade to see full signal details →

Insider trades have triggered activity signals for Enanta Pharmaceuticals Inc. Upgrade to see score, net flow, insiders and the full signal context.

Open in Activity Signals screener →
Top insiders
Trades
Proposed sale 5 Dec 2025
Value US$1,788,048.23 | Price 327.75 | Shares 70,080
Sale 5 Dec 2025
Value US$3,923,021.59 | Price 120.36 | Shares 75,522 (-43.8%)
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-12-05 2025-12-05 PrS Proposed sale
3.1
Luly Jay R.

Officer; Director

Executive Director
70,080
327.75
US$1,788,048 		70,080 327.75 US$1,788,048
2025-12-05 2025-12-05 S Sale
2.5
Luu Brendan

Chief Business Officer

Officer
6,497 +23.3%
97.95
US$2,520,076 		6,497 +23.3% 97.95 US$2,520,076
2025-12-05 2025-12-05 S Sale
2.5
Trout Harry R. III

See Remarks

Officer
18,899 +2.7%
409.85
US$1,088,143 		18,899 +2.7% 409.85 US$1,088,143
2025-12-05 2025-12-05 S Sale
2.6
Capps Kathleen S.

See Remarks

Officer
323 -3.7%
14.23
US$4,596 		323 -3.7% 14.23 US$4,596
2025-12-05 2025-12-05 S Sale
2.6
Kieffer Tara Lynn

Chief Product Strategy Officer

Officer
2,106 -6.4%
14.23
US$29,968 		2,106 -6.4% 14.23 US$29,968
2025-12-05 2025-12-05 S Sale
2.6
Or Yat Sun

Chief Scientific Officer

Officer
2,390 -0.6%
14.23
US$34,010 		2,390 -0.6% 14.23 US$34,010
2025-12-05 2025-12-05 S Sale
2.9
Rottinghaus Scott T.

Chief Medical Officer

Officer
798 -3.5%
14.23
US$11,356 		798 -3.5% 14.23 US$11,356
2025-12-05 2025-12-05 S Sale
3.1
Luly Jay R.

President and CEO

Executive Director
4,743 -0.5%
14.23
US$67,493 		4,743 -0.5% 14.23 US$67,493
2025-12-03 2025-12-02 S Sale
2.5
Trout Harry R. III

See Remarks

Officer
380 -2.2%
13.96
US$5,305 		380 -2.2% 13.96 US$5,305
2025-12-03 2025-12-02 S Sale
2.6
Capps Kathleen S.

See Remarks

Officer
207 -2.3%
13.96
US$2,890 		207 -2.3% 13.96 US$2,890
2025-02-12 2025-02-12 B Purchase
3.1
Luly Jay R.

President and CEO

Executive Director
45,000 +5.6%
5.69
US$256,050 		45,000 +5.6% 5.69 US$256,050
2024-12-10 2024-12-06 S Sale
2.6
Kieffer Tara Lynn

Chief Product Strategy Officer

Officer
2,283 -7.2%
8.06
US$18,401 		2,283 -7.2% 8.06 US$18,401
2024-12-10 2024-12-06 S Sale
2.6
Or Yat Sun

Chief Scientific Officer

Officer
2,591 -0.7%
8.06
US$20,883 		2,591 -0.7% 8.06 US$20,883
2024-12-10 2024-12-06 S Sale
2.5
Luu Brendan

Chief Business Officer

Officer
2,283 -6.0%
8.06
US$18,401 		2,283 -6.0% 8.06 US$18,401
2024-12-10 2024-12-06 S Sale
2.9
Rottinghaus Scott T.

Chief Medical Officer

Officer
866 -4.6%
8.06
US$6,980 		866 -4.6% 8.06 US$6,980
2024-12-10 2024-12-06 S Sale
2.0
MELLETT PAUL J

Chief Fin. & Admin Officer

Officer
2,591 -2.7%
8.06
US$20,883 		2,591 -2.7% 8.06 US$20,883
2024-12-10 2024-12-06 S Sale
3.1
Luly Jay R.

President and CEO

Executive Director
5,142 -0.6%
8.06
US$41,445 		5,142 -0.6% 8.06 US$41,445
2024-07-15 2024-07-15 PlS Planned sale
2.9
Rottinghaus Scott T.

Chief Medical Officer

Officer
5,375 -19.8%
17.08
US$91,805 		5,375 -19.8% 17.08 US$91,805
2024-07-15 2024-07-12 PlS Planned sale
2.9
Rottinghaus Scott T.

Chief Medical Officer

Officer
2,271 -9.5%
15.04
US$34,156 		2,271 -9.5% 15.04 US$34,156
2024-07-15 2024-07-11 PlS Planned sale
2.9
Rottinghaus Scott T.

Chief Medical Officer

Officer
4,299 -15.2%
15.07
US$64,786 		4,299 -15.2% 15.07 US$64,786
2024-07-11 2024-07-11 PrS Proposed sale
2.9
Scott T. Rottinghaus

Officer

Officer
11,945
14.96
US$178,697 		11,945 14.96 US$178,697
2024-06-17 2024-06-17 PrS Proposed sale
2.6
Tara Lynn Kieffer

Officer

Officer
7,266
12.71
US$92,351 		7,266 12.71 US$92,351
2024-06-17 2024-06-17 PlS Planned sale
2.6
Kieffer Tara Lynn

Chief Product Strategy Officer

Officer
7,266 -18.3%
12.33
US$89,590 		7,266 -18.3% 12.33 US$89,590
2023-12-15 2023-12-13 S Sale
0.5
Vance Terry
Non-Executive Director
15,295 -72.5%
9.12
US$139,490 		15,295 -72.5% 9.12 US$139,490
2023-12-12 2023-12-13 PrS Proposed sale
0.5
Vance Terry

Director

Non-Executive Director
15,295
9.06
US$138,573 		15,295 9.06 US$138,573
2023-12-06 2023-12-05 S Sale
2.6
Kieffer Tara Lynn

Sr. VP, New Prod. Strat. & Dev

Officer
2,125 -5.4%
9.63
US$20,464 		2,125 -5.4% 9.63 US$20,464
2023-12-06 2023-12-05 S Sale
2.0
MELLETT PAUL J

Sr. VP, Finance & Admin. & CFO

Officer
2,412 -2.5%
9.63
US$23,228 		2,412 -2.5% 9.63 US$23,228
2023-12-06 2023-12-05 S Sale
2.6
Or Yat Sun

Sr. VP, R&D & CSO

Officer
2,412 -0.6%
9.63
US$23,228 		2,412 -0.6% 9.63 US$23,228
2023-12-06 2023-12-05 S Sale
2.5
Luu Brendan

Sr. VP, Business Dev.

Officer
2,125 -5.5%
9.63
US$20,464 		2,125 -5.5% 9.63 US$20,464
2023-12-06 2023-12-05 S Sale
2.9
Rottinghaus Scott T.

Sr. VP & CMO

Officer
534 -2.0%
9.63
US$5,142 		534 -2.0% 9.63 US$5,142
2023-12-06 2023-12-05 S Sale
3.1
Luly Jay R.

President and CEO

Executive Director
7,230 -0.9%
9.63
US$69,625 		7,230 -0.9% 9.63 US$69,625
2023-12-06 2023-12-05 S Sale
0.5
Gardiner Nathaniel S.

Sr. VP & General Counsel

Officer
2,412 -3.4%
9.63
US$23,228 		2,412 -3.4% 9.63 US$23,228
2023-03-17 2023-03-15 PlS Planned sale
2.0
MELLETT PAUL J

Treasurer and CFO

Officer
10,340 -9.6%
44.43
US$459,406 		10,340 -9.6% 44.43 US$459,406
2023-03-17 2023-03-15 PlS Planned sale
2.0
MELLETT PAUL J

Treasurer and CFO

Officer
100 -0.1%
43.96
US$4,396 		100 -0.1% 43.96 US$4,396
2023-03-17 2023-03-15 PlS Planned sale
2.6
Or Yat Sun

Sr. VP & CSO

Officer
13,656 -3.5%
44.46
US$607,146 		13,656 -3.5% 44.46 US$607,146
2023-03-17 2023-03-15 PlS Planned sale
2.6
Or Yat Sun

Sr. VP & CSO

Officer
269 -0.1%
43.92
US$11,814 		269 -0.1% 43.92 US$11,814
2023-03-14 2023-03-13 PlS Planned sale
3.1
Luly Jay R.

President and CEO

Executive Director
1,566 -0.2%
46.13
US$72,240 		1,566 -0.2% 46.13 US$72,240
2023-03-14 2023-03-13 PlS Planned sale
3.1
Luly Jay R.

President and CEO

Executive Director
15,649 -1.9%
45.31
US$709,056 		15,649 -1.9% 45.31 US$709,056
2023-03-14 2023-03-13 PlS Planned sale
3.1
Luly Jay R.

President and CEO

Executive Director
10,697 -1.3%
44.81
US$479,333 		10,697 -1.3% 44.81 US$479,333
2023-02-13 2023-02-09 PlS Planned sale
2.0
MELLETT PAUL J

Treasurer and CFO

Officer
800 -0.9%
54.41
US$43,528 		800 -0.9% 54.41 US$43,528
2023-02-13 2023-02-09 PlS Planned sale
2.0
MELLETT PAUL J

Treasurer and CFO

Officer
4,200 -4.7%
53.64
US$225,288 		4,200 -4.7% 53.64 US$225,288
2022-12-16 2022-12-16 PlS Planned sale
3.1
Luly Jay R.

President and CEO

Executive Director
13,603 -1.7%
45.49
US$618,800 		13,603 -1.7% 45.49 US$618,800
2022-12-16 2022-12-16 PlS Planned sale
3.1
Luly Jay R.

President and CEO

Executive Director
8,597 -1.1%
44.54
US$382,910 		8,597 -1.1% 44.54 US$382,910
2022-12-16 2022-12-16 PlS Planned sale
3.1
Luly Jay R.

President and CEO

Executive Director
7,800 -1.0%
43.59
US$340,002 		7,800 -1.0% 43.59 US$340,002
2022-04-05 2022-04-04 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
9,009 -20.5%
73.42
US$661,441 		9,009 -20.5% 73.42 US$661,441
2022-04-05 2022-04-04 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
3,200 -6.8%
72.65
US$232,480 		3,200 -6.8% 72.65 US$232,480
2022-04-05 2022-04-04 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
18,076 -27.7%
71.71
US$1,296,230 		18,076 -27.7% 71.71 US$1,296,230
2022-04-05 2022-04-04 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
2,500 -3.7%
70.56
US$176,400 		2,500 -3.7% 70.56 US$176,400
2022-04-05 2022-04-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
42,260 -54.7%
71.32
US$3,013,983 		42,260 -54.7% 71.32 US$3,013,983
2022-04-05 2022-04-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
8,299 -9.7%
70.75
US$587,154 		8,299 -9.7% 70.75 US$587,154
2022-03-22 2022-03-21 PlS Planned sale
2.6
CARTER BRUCE L A
Non-Executive Director
807 -100.0%
69.52
US$56,103 		807 -100.0% 69.52 US$56,103
2022-03-22 2022-03-21 PlS Planned sale
2.6
CARTER BRUCE L A
Non-Executive Director
2,210 -73.3%
68.66
US$151,739 		2,210 -73.3% 68.66 US$151,739
2022-03-22 2022-03-21 PlS Planned sale
2.6
CARTER BRUCE L A
Non-Executive Director
307 -9.2%
67.23
US$20,640 		307 -9.2% 67.23 US$20,640
2022-03-22 2022-03-21 PlS Planned sale
2.6
CARTER BRUCE L A
Non-Executive Director
2,676 -44.6%
66.70
US$178,489 		2,676 -44.6% 66.70 US$178,489
2022-03-03 2022-03-02 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
12,481 -26.3%
70.07
US$874,544 		12,481 -26.3% 70.07 US$874,544
2022-03-03 2022-03-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
100 -0.3%
71.06
US$7,106 		100 -0.3% 71.06 US$7,106
2022-03-03 2022-03-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
24,239 -40.9%
70.26
US$1,703,032 		24,239 -40.9% 70.26 US$1,703,032
2022-01-13 2022-01-11 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
12,536 -27.6%
70.13
US$879,150 		12,536 -27.6% 70.13 US$879,150
2021-12-03 2021-12-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
201 -0.6%
90.17
US$18,124 		201 -0.6% 90.17 US$18,124
2021-12-03 2021-12-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
899 -2.6%
89.33
US$80,308 		899 -2.6% 89.33 US$80,308
2021-12-03 2021-12-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
900 -2.6%
88.31
US$79,479 		900 -2.6% 88.31 US$79,479
2021-12-03 2021-12-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
1,500 -4.1%
87.60
US$131,400 		1,500 -4.1% 87.60 US$131,400
2021-12-03 2021-12-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
2,700 -6.9%
86.45
US$233,415 		2,700 -6.9% 86.45 US$233,415
2021-12-03 2021-12-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
5,736 -12.8%
85.49
US$490,371 		5,736 -12.8% 85.49 US$490,371
2021-12-03 2021-12-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
1,587 -3.4%
84.81
US$134,593 		1,587 -3.4% 84.81 US$134,593
2021-11-02 2021-11-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
100 -0.4%
86.21
US$8,621 		100 -0.4% 86.21 US$8,621
2021-11-02 2021-11-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
7,495 -21.7%
85.02
US$637,225 		7,495 -21.7% 85.02 US$637,225
2021-11-02 2021-11-01 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
1,952 -5.3%
84.31
US$164,573 		1,952 -5.3% 84.31 US$164,573
2021-10-13 2021-10-11 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
4,047 -13.1%
70.34
US$284,685 		4,047 -13.1% 70.34 US$284,685
2021-10-13 2021-10-08 PlS Planned sale
Adda Nathalie

Sr. VP & Chief Medical Officer

Officer
13,453 -33.3%
70.09
US$942,934 		13,453 -33.3% 70.09 US$942,934
2021-09-17 2021-09-15 PlS Planned sale
3.1
Luly Jay R.

President and CEO

Executive Director
4,516 -0.7%
59.06
US$266,698 		4,516 -0.7% 59.06 US$266,698
2021-01-08 2021-01-08 PlS Planned sale
2.0
MELLETT PAUL J

Treasurer and CFO

Officer
6,000 -8.9%
45.58
US$273,463 		6,000 -8.9% 45.58 US$273,463
2020-01-06 2020-01-02 PlS Planned sale
2.0
MELLETT PAUL J

Treasurer and CFO

Officer
721 -1.8%
61.66
US$44,458 		721 -1.8% 61.66 US$44,458
2020-01-06 2020-01-02 PlS Planned sale
2.0
MELLETT PAUL J

Treasurer and CFO

Officer
9,279 -18.5%
60.82
US$564,341 		9,279 -18.5% 60.82 US$564,341
2019-03-12 2019-03-11 PlS Planned sale
2.6
CARTER BRUCE L A
1,546 -100.0%
99.16
US$153,301 		1,546 -100.0% 99.16 US$153,301
Explore more

More insider trading research around Enanta Pharmaceuticals Inc

More insider trades in United States
Similar Healthcare companies with insider activity
More Pharmaceuticals & Medical Research companies with insider activity
More Biotechnology & Medical Research companies with insider activity
Insider trading in North America