United States Pharmaceuticals

Cocrystal Pharma Inc (COCP)

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The most recent insider trading activity at Cocrystal Pharma Inc. occurred on February 24, 2026. All recent transactions involved consistent open-market purchases by Phillip Frost MD et al., spanning from November 2025 through February 2026. These acquisitions represent a series of buy orders totaling several hundred thousand shares over the observed period.
Ticker: COCP Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Cocrystal Pharma Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Trades
Buy 24 Feb 2026
Value US$3,859,042.26 | Price 432.87 | Shares 31,063 (-31.2%)
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-02-25 2026-02-24 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
31,063 -31.2%
432.87
US$3,859,042 		31,063 -31.2% 432.87 US$3,859,042
2026-02-09 2026-02-06 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
39,583 -34.4%
100.60
US$1,395,234 		39,583 -34.4% 100.60 US$1,395,234
2026-01-02 2025-12-31 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
21,898 -48.8%
383.72
US$3,203,635 		21,898 -48.8% 383.72 US$3,203,635
2025-12-31 2025-12-30 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
20,000 +1.1%
0.97
US$19,310 		20,000 +1.1% 0.97 US$19,310
2025-12-29 2025-12-26 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
40,000 +2.3%
0.97
US$38,944 		40,000 +2.3% 0.97 US$38,944
2025-12-29 2025-12-24 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
25,000 +1.5%
0.97
US$24,258 		25,000 +1.5% 0.97 US$24,258
2025-11-28 2025-11-26 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
2,500 +0.1%
0.99
US$2,475 		2,500 +0.1% 0.99 US$2,475
2025-11-28 2025-11-26 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
1,500 +0.1%
1.00
US$1,500 		1,500 +0.1% 1.00 US$1,500
2025-11-25 2025-11-25 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
20,000 +1.2%
0.94
US$18,812 		20,000 +1.2% 0.94 US$18,812
2023-04-06 2023-04-04 B Purchase
2.3
FROST PHILLIP MD ET AL
Non-Executive Director Large shareholder
1,015,229 +333.3%
1.97
US$2,000,001 		1,015,229 +333.3% 1.97 US$2,000,001
2019-10-29 2019-10-25 B Purchase
1.1
Schinazi Raymond F
Large shareholder
7,906 +0.1%
1.15
US$9,092 		7,906 +0.1% 1.15 US$9,092
2019-10-29 2019-10-24 B Purchase
1.1
Schinazi Raymond F
Large shareholder
5,094 +0.1%
1.15
US$5,858 		5,094 +0.1% 1.15 US$5,858
2019-10-29 2019-10-23 B Purchase
1.1
Schinazi Raymond F
Large shareholder
3,935 +0.0%
1.04
US$4,087 		3,935 +0.0% 1.04 US$4,087
2016-12-23 2016-12-23 S Sale Lee Sam

PRESIDENT

Officer
2,200,000 -14.4%
0.44
US$968,000 		2,200,000 -14.4% 0.44 US$968,000
2016-09-06 2016-09-01 B Purchase WILCOX GARY

INTERIM CEO

Executive Director
10,000 +0.1%
0.41
US$4,100 		10,000 +0.1% 0.41 US$4,100
2016-09-06 2016-09-01 B Purchase BLOCK DAVID S Non-Executive Director
10,000 +6.3%
0.41
US$4,100 		10,000 +6.3% 0.41 US$4,100
2016-09-06 2016-09-01 B Purchase Schinazi Raymond F Non-Executive Director Large shareholder
4,878,050 +inf%
0.41
US$2,000,000 		4,878,050 +inf% 0.41 US$2,000,000
2016-03-17 2016-03-15 B Purchase BLOCK DAVID S Non-Executive Director
50,000 +46.0%
0.51
US$25,500 		50,000 +46.0% 0.51 US$25,500
2016-03-17 2016-03-15 B Purchase FROST PHILLIP MD ET AL Non-Executive Director Large shareholder
2,941,177 +2.8%
0.51
US$1,500,000 		2,941,177 +2.8% 0.51 US$1,500,000
2016-03-17 2016-03-15 B Purchase HSIAO JANE PH D Non-Executive Director
1,235,294 +56.1%
0.51
US$630,000 		1,235,294 +56.1% 0.51 US$630,000
2016-03-17 2016-03-15 B Purchase Schinazi Raymond F Non-Executive Director Large shareholder
2,941,176 +1.1%
0.51
US$1,500,000 		2,941,176 +1.1% 0.51 US$1,500,000
2016-03-17 2016-03-15 B Purchase WILCOX GARY Non-Executive Director
49,020 +0.3%
0.51
US$25,000 		49,020 +0.3% 0.51 US$25,000
2016-03-17 2016-03-15 B Purchase Meckler Jeffrey A

CHIEF EXECUTIVE OFFICER

Executive Director
294,118 +81.0%
0.51
US$150,000 		294,118 +81.0% 0.51 US$150,000
2016-03-17 2016-03-15 B Purchase Rubin Steven D Non-Executive Director
39,216 +72.2%
0.51
US$20,000 		39,216 +72.2% 0.51 US$20,000
2015-12-28 2015-12-23 B Purchase Meckler Jeffrey A

CHIEF EXECUTIVE OFFICER

Executive Director
100,000 +38.0%
0.58
US$57,870 		100,000 +38.0% 0.58 US$57,870
2015-04-23 2015-04-21 B Purchase Schinazi Raymond F Non-Executive Director Large shareholder
3,464,855 +1.3%
0.92
US$3,187,667 		3,464,855 +1.3% 0.92 US$3,187,667
2015-03-27 2015-03-25 B Purchase Meckler Jeffrey A Non-Executive Director
163,043 +163.0%
0.92
US$150,000 		163,043 +163.0% 0.92 US$150,000
2015-03-27 2015-03-25 B Purchase FROST PHILLIP MD ET AL Non-Executive Director Large shareholder
3,464,855 +3.5%
0.92
US$3,187,667 		3,464,855 +3.5% 0.92 US$3,187,667
2015-03-27 2015-03-25 B Purchase BLOCK DAVID S Non-Executive Director
108,696 +inf%
0.92
US$100,000 		108,696 +inf% 0.92 US$100,000
2015-03-27 2015-03-25 B Purchase HSIAO JANE PH D Non-Executive Director
2,200,000 +inf%
0.92
US$2,024,000 		2,200,000 +inf% 0.92 US$2,024,000
2015-03-27 2015-03-25 B Purchase WILCOX GARY

CHIEF EXECUTIVE OFFICER

Executive Director
54,348 +0.3%
0.92
US$50,000 		54,348 +0.3% 0.92 US$50,000
2015-03-27 2015-03-25 B Purchase Rubin Steven D Non-Executive Director
54,348 +8.5%
0.92
US$50,000 		54,348 +8.5% 0.92 US$50,000
2014-12-17 2014-12-15 B Purchase FROST PHILLIP MD ET AL Non-Executive Director Large shareholder
10,000 +0.1%
0.44
US$4,350 		10,000 +0.1% 0.44 US$4,350
2014-12-17 2014-12-15 B Purchase FROST PHILLIP MD ET AL Non-Executive Director Large shareholder
8,873 +0.1%
0.43
US$3,815 		8,873 +0.1% 0.43 US$3,815
2014-12-17 2014-12-15 B Purchase FROST PHILLIP MD ET AL Non-Executive Director Large shareholder
6,127 +0.0%
0.43
US$2,604 		6,127 +0.0% 0.43 US$2,604
2014-12-15 2014-12-11 B Purchase Meckler Jeffrey A Non-Executive Director
50,000 +100.0%
0.46
US$23,000 		50,000 +100.0% 0.46 US$23,000
2014-12-15 2014-12-11 B Purchase Meckler Jeffrey A Non-Executive Director
25,000 +100.0%
0.45
US$11,360 		25,000 +100.0% 0.45 US$11,360
2014-12-15 2014-12-11 B Purchase Meckler Jeffrey A Non-Executive Director
25,000 +inf%
0.45
US$11,250 		25,000 +inf% 0.45 US$11,250
2014-08-13 2014-08-12 B Purchase FROST PHILLIP MD ET AL Non-Executive Director Large shareholder
66,200 +0.5%
0.29
US$19,397 		66,200 +0.5% 0.29 US$19,397
2014-08-13 2014-08-11 B Purchase FROST PHILLIP MD ET AL Non-Executive Director Large shareholder
45,000 +0.4%
0.29
US$13,010 		45,000 +0.4% 0.29 US$13,010
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