|
2023-05-09 |
2023-05-05 |
B
Purchase
|
Large shareholder
|
75,799
34.15
US$4,217,410
|
75,799
|
34.15
|
US$4,217,410
|
|
|
2023-05-09 |
2023-05-05 |
B
Purchase
|
Large shareholder
|
95,567
432.71
US$4,019,283
|
95,567
|
432.71
|
US$4,019,283
|
|
|
2023-05-09 |
2023-05-05 |
B
Purchase
|
Large shareholder
|
97,162
261.41
US$222,228
|
97,162
|
261.41
|
US$222,228
|
|
|
2022-11-23 |
2022-11-23 |
B
Purchase
|
President
Executive Director
|
1,000
+inf%
2.60
US$2,597
|
1,000
+inf%
|
2.60
|
US$2,597
|
|
|
2021-12-21 |
2021-12-20 |
B
Purchase
|
Chief Executive Officer
Executive Director
|
2,000
+28.6%
4.48
US$8,960
|
2,000
+28.6%
|
4.48
|
US$8,960
|
|
|
2021-06-14 |
2021-06-11 |
B
Purchase
|
CHIEF FINANCIAL OFFICER
Officer
|
10,000
+inf%
8.87
US$88,700
|
10,000
+inf%
|
8.87
|
US$88,700
|
|
|
2021-06-10 |
2021-06-09 |
B
Purchase
|
Chief Executive Officer
Executive Director
|
3,000
+inf%
8.01
US$24,030
|
3,000
+inf%
|
8.01
|
US$24,030
|
|
|
2020-12-04 |
2020-12-02 |
S
Sale
|
Large shareholder
|
103,200
-58.4%
21.60
US$2,229,120
|
103,200
-58.4%
|
21.60
|
US$2,229,120
|
|
|
2020-11-06 |
2020-10-30 |
B
Purchase
|
Large shareholder
|
9,098
+4.2%
25.55
US$232,460
|
9,098
+4.2%
|
25.55
|
US$232,460
|
|
|
2020-11-06 |
2020-10-30 |
B
Purchase
|
Large shareholder
|
15,000
+7.5%
26.17
US$392,610
|
15,000
+7.5%
|
26.17
|
US$392,610
|
|
|
2020-11-06 |
2020-10-30 |
S
Sale
|
Large shareholder
|
27
-0.0%
27.02
US$730
|
27
-0.0%
|
27.02
|
US$730
|
|
|
2020-11-06 |
2020-10-30 |
B
Purchase
|
Large shareholder
|
12,942
+6.9%
25.88
US$334,926
|
12,942
+6.9%
|
25.88
|
US$334,926
|
|
|
2020-11-06 |
2020-10-30 |
S
Sale
|
Large shareholder
|
12,942
-6.5%
26.64
US$344,829
|
12,942
-6.5%
|
26.64
|
US$344,829
|
|
|
2020-11-06 |
2020-10-30 |
B
Purchase
|
Large shareholder
|
15,000
+8.1%
26.48
US$397,236
|
15,000
+8.1%
|
26.48
|
US$397,236
|
|
|
2020-11-06 |
2020-10-30 |
B
Purchase
|
Large shareholder
|
4,000
+2.2%
25.97
US$103,892
|
4,000
+2.2%
|
25.97
|
US$103,892
|
|
|
2020-11-06 |
2020-10-30 |
B
Purchase
|
Large shareholder
|
31,000
+20.7%
24.53
US$760,427
|
31,000
+20.7%
|
24.53
|
US$760,427
|
|
|
2020-11-06 |
2020-10-30 |
B
Purchase
|
Large shareholder
|
5,000
+3.4%
24.03
US$120,162
|
5,000
+3.4%
|
24.03
|
US$120,162
|
|
|
2019-05-22 |
2019-05-21 |
S
Sale
|
Chief Executive Officer
|
2,937
-1.8%
1.91
US$5,614
|
2,937
-1.8%
|
1.91
|
US$5,614
|
|
|
2019-05-22 |
2019-05-21 |
S
Sale
|
See Remarks
|
1,058
-15.0%
1.91
US$2,022
|
1,058
-15.0%
|
1.91
|
US$2,022
|
|
|
2019-05-22 |
2019-05-21 |
S
Sale
|
President
|
1,914
-2.1%
1.91
US$3,658
|
1,914
-2.1%
|
1.91
|
US$3,658
|
|
|
2019-05-22 |
2019-05-20 |
S
Sale
|
Chief Executive Officer
|
11,701
-6.8%
1.96
US$22,953
|
11,701
-6.8%
|
1.96
|
US$22,953
|
|
|
2019-05-22 |
2019-05-20 |
S
Sale
|
See Remarks
|
4,218
-37.5%
1.96
US$8,274
|
4,218
-37.5%
|
1.96
|
US$8,274
|
|
|
2019-05-22 |
2019-05-20 |
S
Sale
|
President
|
7,623
-7.8%
1.96
US$14,953
|
7,623
-7.8%
|
1.96
|
US$14,953
|
|
|
2019-05-06 |
2019-05-02 |
B
Purchase
|
|
646,204
+25.5%
3.10
US$2,003,232
|
646,204
+25.5%
|
3.10
|
US$2,003,232
|
|
|
2019-05-06 |
2019-05-02 |
B
Purchase
|
Large shareholder
|
646,204
+25.5%
3.10
US$2,003,232
|
646,204
+25.5%
|
3.10
|
US$2,003,232
|
|
|
2019-05-02 |
2019-04-30 |
S
Sale
|
Large shareholder
|
200
-0.0%
2.70
US$540
|
200
-0.0%
|
2.70
|
US$540
|
|
|
2018-09-13 |
2018-09-12 |
B
Purchase
|
TURKEL CATHERINE C.
President
Officer
|
16,632
+27.0%
5.02
US$83,476
|
16,632
+27.0%
|
5.02
|
US$83,476
|
|
|
2018-09-13 |
2018-09-11 |
B
Purchase
|
TURKEL CATHERINE C.
President
Officer
|
17,048
+38.3%
4.56
US$77,671
|
17,048
+38.3%
|
4.56
|
US$77,671
|
|
|
2018-09-07 |
2018-09-05 |
B
Purchase
|
TURKEL CATHERINE C.
President
Officer
|
805
+inf%
3.97
US$3,193
|
805
+inf%
|
3.97
|
US$3,193
|
|
|
2017-05-11 |
2017-05-10 |
B
Purchase
|
FLESHER GREGORY J.
Chief Executive Officer
Executive Director
|
58,959
+103.6%
9.99
US$589,000
|
58,959
+103.6%
|
9.99
|
US$589,000
|
|
|
2017-05-11 |
2017-05-10 |
B
Purchase
|
TURKEL CATHERINE C.
Chief Development Officer
Officer
|
11,111
+82.9%
9.99
US$110,999
|
11,111
+82.9%
|
9.99
|
US$110,999
|
|
|
2017-05-11 |
2017-05-10 |
B
Purchase
|
OCAMPO CHRISTINE
See Remarks
Officer
|
10,010
+86.4%
9.99
US$100,000
|
10,010
+86.4%
|
9.99
|
US$100,000
|
|
|
2016-03-15 |
2016-03-15 |
B
Purchase
|
Buckley Stephen Jr.
Non-Executive Director
|
8,000
+266.7%
5.74
US$45,920
|
8,000
+266.7%
|
5.74
|
US$45,920
|
|
|
2015-11-12 |
2015-11-11 |
B
Purchase
|
Buckley Stephen Jr.
Non-Executive Director
|
3,000
+inf%
11.25
US$33,750
|
3,000
+inf%
|
11.25
|
US$33,750
|
|
|
2015-09-22 |
2015-09-21 |
PlS
Planned sale
|
McBride John S.
Chief Operating Officer
Officer
|
13,500
-100.0%
14.01
US$189,135
|
13,500
-100.0%
|
14.01
|
US$189,135
|
|
|
2015-07-30 |
2015-07-29 |
PlS
Planned sale
|
Morrison Jodie Pope
President and CEO
Executive Director
|
564
-2.8%
13.70
US$7,727
|
564
-2.8%
|
13.70
|
US$7,727
|
|
|
2015-07-30 |
2015-07-28 |
PlS
Planned sale
|
Morrison Jodie Pope
President and CEO
Executive Director
|
12,000
-38.0%
13.70
US$164,400
|
12,000
-38.0%
|
13.70
|
US$164,400
|
|
|
2015-07-17 |
2015-07-15 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
3,566
-0.1%
14.26
US$50,844
|
3,566
-0.1%
|
14.26
|
US$50,844
|
|
|
2015-07-15 |
2015-07-14 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
27,861
-0.6%
14.41
US$401,477
|
27,861
-0.6%
|
14.41
|
US$401,477
|
|
|
2015-07-15 |
2015-07-13 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
20,611
-0.5%
14.20
US$292,717
|
20,611
-0.5%
|
14.20
|
US$292,717
|
|
|
2015-06-30 |
2015-06-29 |
PlS
Planned sale
|
Morrison Jodie Pope
President and CEO
Executive Director
|
8,000
-45.6%
13.70
US$109,600
|
8,000
-45.6%
|
13.70
|
US$109,600
|
|
|
2015-06-30 |
2015-06-26 |
PlS
Planned sale
|
Morrison Jodie Pope
President and CEO
Executive Director
|
8,000
-45.6%
13.83
US$110,640
|
8,000
-45.6%
|
13.83
|
US$110,640
|
|
|
2015-06-24 |
2015-06-24 |
PlS
Planned sale
|
McBride John S.
Chief Operating Officer
Officer
|
300
-100.0%
14.20
US$4,260
|
300
-100.0%
|
14.20
|
US$4,260
|
|
|
2015-06-24 |
2015-06-23 |
PlS
Planned sale
|
McBride John S.
Chief Operating Officer
Officer
|
6,700
-100.0%
14.00
US$93,800
|
6,700
-100.0%
|
14.00
|
US$93,800
|
|
|
2015-06-24 |
2015-06-22 |
PlS
Planned sale
|
McBride John S.
Chief Operating Officer
Officer
|
2,000
-100.0%
14.02
US$28,040
|
2,000
-100.0%
|
14.02
|
US$28,040
|
|
|
2015-06-18 |
2015-06-16 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
1,120
-0.0%
14.27
US$15,982
|
1,120
-0.0%
|
14.27
|
US$15,982
|
|
|
2015-06-16 |
2015-06-12 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
5,919
-0.1%
14.20
US$84,050
|
5,919
-0.1%
|
14.20
|
US$84,050
|
|
|
2015-06-12 |
2015-06-11 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
27,875
-0.6%
14.20
US$395,825
|
27,875
-0.6%
|
14.20
|
US$395,825
|
|
|
2015-03-20 |
2015-03-19 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
46,141
-1.0%
14.50
US$669,044
|
46,141
-1.0%
|
14.50
|
US$669,044
|
|
|
2015-03-20 |
2015-03-18 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
3,000
-0.1%
14.50
US$43,500
|
3,000
-0.1%
|
14.50
|
US$43,500
|
|
|
2014-09-24 |
2014-09-22 |
B
Purchase
|
Apple Tree Partners II - Annex, L.P.
Non-Executive Director
Large shareholder
|
237,500
+7.1%
15.00
US$3,562,500
|
237,500
+7.1%
|
15.00
|
US$3,562,500
|
|
|
2014-09-24 |
2014-09-22 |
B
Purchase
|
Novartis Bioventures Ltd
Large shareholder
|
325,000
+7.5%
15.00
US$4,875,000
|
325,000
+7.5%
|
15.00
|
US$4,875,000
|
|
|
2014-09-24 |
2014-09-22 |
B
Purchase
|
Harrison Seth Loring
Non-Executive Director
Large shareholder
|
362,500
+4.8%
15.00
US$5,437,500
|
362,500
+4.8%
|
15.00
|
US$5,437,500
|
|
|
2014-09-24 |
2014-09-22 |
B
Purchase
|
Satter Muneer A
Large shareholder
|
150,000
+9.2%
15.00
US$2,250,000
|
150,000
+9.2%
|
15.00
|
US$2,250,000
|
|
|
2015-06-16 |
2014-06-15 |
S
Sale
|
Novartis Bioventures Ltd
Large shareholder
|
14,777
-0.3%
14.20
US$209,833
|
14,777
-0.3%
|
14.20
|
US$209,833
|
|