|
2008-05-30 |
2008-05-28 |
B
Purchase
|
BRENNAN EDWARD F
CEO and President
Executive Director
|
67,231
+32.2%
361.18
US$3,795,912
|
67,231
+32.2%
|
361.18
|
US$3,795,912
|
|
|
2008-05-30 |
2008-05-28 |
B
Purchase
|
BRENNAN EDWARD F
CEO and President
Executive Director
|
75,427
-23.3%
104.17
US$4,118,953
|
75,427
-23.3%
|
104.17
|
US$4,118,953
|
|
|
2008-05-30 |
2008-05-28 |
B
Purchase
|
Griffin Jerry C
Non-Executive Director
|
25,520
+12.3%
314.21
US$2,197,711
|
25,520
+12.3%
|
314.21
|
US$2,197,711
|
|
|
2008-05-30 |
2008-05-28 |
B
Purchase
|
Tibbitts Gregory J
CFO & VP, Finance
Officer
|
5,750
+2.6%
0.62
US$3,565
|
5,750
+2.6%
|
0.62
|
US$3,565
|
|
|
2008-05-30 |
2008-05-28 |
B
Purchase
|
BRENNAN EDWARD F
CEO and President
Executive Director
|
101,828
+23.8%
0.62
US$63,133
|
101,828
+23.8%
|
0.62
|
US$63,133
|
|
|
2008-05-30 |
2008-05-28 |
B
Purchase
|
Griffin Jerry C
Non-Executive Director
|
14,808
+inf%
0.62
US$9,181
|
14,808
+inf%
|
0.62
|
US$9,181
|
|
|
2008-05-30 |
2008-05-28 |
B
Purchase
|
Tibbitts Gregory J
CFO & VP, Finance
Officer
|
28,332
+14.5%
0.62
US$17,566
|
28,332
+14.5%
|
0.62
|
US$17,566
|
|
|
2007-08-16 |
2007-08-15 |
B
Purchase
|
Barold Helen S
Chief Medical Officer
Officer
|
1,000
+100.0%
3.49
US$3,490
|
1,000
+100.0%
|
3.49
|
US$3,490
|
|
|
2007-04-26 |
2007-04-24 |
B
Purchase
|
William Blair Capital Management VII, LLC
Large shareholder
|
96,553
+5.2%
5.14
US$496,282
|
96,553
+5.2%
|
5.14
|
US$496,282
|
|
|
2007-04-26 |
2007-04-24 |
B
Purchase
|
MINOCHERHOMJEE ARDA
Non-Executive Director
Large shareholder
|
96,553
+5.2%
5.14
US$496,282
|
96,553
+5.2%
|
5.14
|
US$496,282
|
|
|
2007-04-25 |
2007-04-24 |
B
Purchase
|
MPM BIOVENTURES II QP LP
Large shareholder
|
96,551
+3.3%
5.14
US$496,272
|
96,551
+3.3%
|
5.14
|
US$496,272
|
|
|
2007-04-25 |
2007-04-24 |
B
Purchase
|
WHEELER KURT
Non-Executive Director
Large shareholder
|
96,551
+3.3%
5.14
US$496,272
|
96,551
+3.3%
|
5.14
|
US$496,272
|
|
|
2006-09-13 |
2006-09-13 |
B
Purchase
|
Barold Helen S
Chief Medical Officer
Officer
|
1,000
+inf%
3.12
US$3,120
|
1,000
+inf%
|
3.12
|
US$3,120
|
|
|
2006-09-01 |
2006-08-30 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
300
-1.0%
2.25
US$675
|
300
-1.0%
|
2.25
|
US$675
|
|
|
2006-08-29 |
2006-08-29 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
300
-1.0%
2.41
US$723
|
300
-1.0%
|
2.41
|
US$723
|
|
|
2006-08-29 |
2006-08-29 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
400
-1.3%
2.40
US$960
|
400
-1.3%
|
2.40
|
US$960
|
|
|
2006-08-29 |
2006-08-29 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
1,500
-4.6%
2.31
US$3,465
|
1,500
-4.6%
|
2.31
|
US$3,465
|
|
|
2006-08-29 |
2006-08-29 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
700
-2.1%
2.27
US$1,589
|
700
-2.1%
|
2.27
|
US$1,589
|
|
|
2006-08-29 |
2006-08-29 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
1,300
-3.7%
2.26
US$2,938
|
1,300
-3.7%
|
2.26
|
US$2,938
|
|
|
2006-08-29 |
2006-08-29 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
200
-0.6%
2.25
US$450
|
200
-0.6%
|
2.25
|
US$450
|
|
|
2006-08-29 |
2006-08-29 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
300
-0.8%
2.23
US$669
|
300
-0.8%
|
2.23
|
US$669
|
|
|
2006-08-18 |
2006-08-16 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
1,000
-2.7%
2.19
US$2,190
|
1,000
-2.7%
|
2.19
|
US$2,190
|
|
|
2006-08-18 |
2006-08-16 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
268
-0.7%
2.21
US$592
|
268
-0.7%
|
2.21
|
US$592
|
|
|
2006-08-18 |
2006-08-16 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
200
-0.5%
2.20
US$440
|
200
-0.5%
|
2.20
|
US$440
|
|
|
2006-08-16 |
2006-08-15 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
1,000
-2.6%
2.25
US$2,250
|
1,000
-2.6%
|
2.25
|
US$2,250
|
|
|
2006-08-16 |
2006-08-15 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
1,000
-2.6%
2.26
US$2,260
|
1,000
-2.6%
|
2.26
|
US$2,260
|
|
|
2006-08-16 |
2006-08-15 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
83
-0.2%
2.35
US$195
|
83
-0.2%
|
2.35
|
US$195
|
|
|
2006-08-16 |
2006-08-14 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
200
-0.5%
2.37
US$474
|
200
-0.5%
|
2.37
|
US$474
|
|
|
2006-08-16 |
2006-08-14 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
349
-0.9%
2.38
US$831
|
349
-0.9%
|
2.38
|
US$831
|
|
|
2006-08-16 |
2006-08-14 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
300
-0.8%
2.40
US$720
|
300
-0.8%
|
2.40
|
US$720
|
|
|
2006-08-16 |
2006-08-14 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
200
-0.5%
2.43
US$486
|
200
-0.5%
|
2.43
|
US$486
|
|
|
2006-08-16 |
2006-08-14 |
B
Purchase
|
Hattendorf Joseph Mark
Non-Executive Director
|
64
+1.6%
2.19
US$140
|
64
+1.6%
|
2.19
|
US$140
|
|
|
2006-08-16 |
2006-08-14 |
B
Purchase
|
Hattendorf Joseph Mark
Non-Executive Director
|
3,800
+2794.1%
2.20
US$8,360
|
3,800
+2794.1%
|
2.20
|
US$8,360
|
|
|
2006-08-16 |
2006-08-14 |
S
Sale
|
Ayers Gregory M
Non-Executive Director
|
400
-1.0%
2.45
US$980
|
400
-1.0%
|
2.45
|
US$980
|
|
|
2006-08-16 |
2006-08-14 |
B
Purchase
|
Hattendorf Joseph Mark
Non-Executive Director
|
136
+inf%
2.50
US$340
|
136
+inf%
|
2.50
|
US$340
|
|
|
2006-03-30 |
2006-03-30 |
B
Purchase
|
BRENNAN EDWARD F
Chief Executive Officer
Officer
|
5,671
+13.9%
3.04
US$17,240
|
5,671
+13.9%
|
3.04
|
US$17,240
|
|
|
2006-03-30 |
2006-03-29 |
B
Purchase
|
Tibbitts Gregory J
VP, Finance & CFO
Officer
|
3,300
+8.1%
3.00
US$9,900
|
3,300
+8.1%
|
3.00
|
US$9,900
|
|
|
2006-03-16 |
2006-03-15 |
B
Purchase
|
BRENNAN EDWARD F
President & COO
Officer
|
483
+1.2%
1.91
US$923
|
483
+1.2%
|
1.91
|
US$923
|
|
|
2006-03-16 |
2006-03-15 |
B
Purchase
|
Tibbitts Gregory J
Vice President, Finance & CFO
Officer
|
483
+1.2%
1.91
US$923
|
483
+1.2%
|
1.91
|
US$923
|
|
|
2005-07-15 |
2005-07-13 |
B
Purchase
|
MINOCHERHOMJEE ARDA
Non-Executive Director
Large shareholder
|
203,000
+inf%
11.00
US$2,233,000
|
203,000
+inf%
|
11.00
|
US$2,233,000
|
|
|
2005-07-15 |
2005-07-13 |
B
Purchase
|
Adelman Robert J
Non-Executive Director
Large shareholder
|
135,000
+inf%
11.00
US$1,485,000
|
135,000
+inf%
|
11.00
|
US$1,485,000
|
|
|
2005-07-15 |
2005-07-13 |
B
Purchase
|
Ayers Gregory M
Chief Executive Officer
Executive Director
|
100
+0.2%
11.00
US$1,100
|
100
+0.2%
|
11.00
|
US$1,100
|
|
|
2005-07-15 |
2005-07-13 |
B
Purchase
|
WHEELER KURT
Non-Executive Director
Large shareholder
|
180,000
+inf%
11.00
US$1,980,000
|
180,000
+inf%
|
11.00
|
US$1,980,000
|
|
|
2005-07-15 |
2005-07-13 |
B
Purchase
|
Cooney David J
Non-Executive Director
|
45,000
+inf%
11.00
US$495,000
|
45,000
+inf%
|
11.00
|
US$495,000
|
|
|
2005-07-14 |
2005-07-13 |
B
Purchase
|
William Blair Capital Management VII, LLC
Large shareholder
|
203,000
+inf%
11.00
US$2,233,000
|
203,000
+inf%
|
11.00
|
US$2,233,000
|
|
|
2005-07-14 |
2005-07-13 |
B
Purchase
|
MPM BIOVENTURES II QP LP
Large shareholder
|
180,000
+inf%
11.00
US$1,980,000
|
180,000
+inf%
|
11.00
|
US$1,980,000
|
|