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United States Biotechnology & Medical Research

Crinetics Pharmaceuticals Inc (CRNX)

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Over the last 90 days, Crinetics Pharmaceuticals Inc. has seen significant insider selling, with total sales exceeding $8.2 million. No insider purchases were recorded. Notable transactions include multiple large sales by officers and directors, such as Jeff Knight and Richard Scott Struthers. The company's stock has experienced a modest 0.5% increase over the same period.
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Ticker: CRNX Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
Okey Stephanie
2 sales — total 200,000 USD
Planned sale 17 Jun 2026
Value US$3,685,316.39 | Price 71.58 | Shares 53,872
Planned sale 17 Jun 2026
Value US$543,937.74 | Price 14.61 | Shares 34,250
Proposed sale 17 Jun 2026
Value US$4,676,618.37 | Price 179.24 | Shares 74,636
Proposed sale 4 May 2026
Value US$370,104.70 | Price 39.02 | Shares 9,485
Proposed sale 14 Apr 2026
Value US$807,994.00 | Price 38.66 | Shares 20,900
Proposed sale 13 Apr 2026
Value US$174,876.96 | Price 39.44 | Shares 4,434
Planned sale 8 Apr 2026
Value US$3,415,036.30 | Price 40.10 | Shares 85,163
Proposed sale 8 Apr 2026
Value US$3,271,110.83 | Price 38.41 | Shares 85,163
Proposed sale 18 Mar 2026
Value US$938,004.84 | Price 37.89 | Shares 24,756
Planned sale 16 Mar 2026
Value US$331,809.45 | Price 37.77 | Shares 8,785
Planned sale 16 Mar 2026
Value US$489,703.56 | Price 37.11 | Shares 13,196
Planned sale 16 Mar 2026
Value US$160,182.57 | Price 37.77 | Shares 4,241
Planned sale 16 Mar 2026
Value US$236,427.81 | Price 37.11 | Shares 6,371
Proposed sale 16 Mar 2026
Value US$994,422.00 | Price 37.49 | Shares 26,525
Proposed sale 16 Mar 2026
Value US$941,486.00 | Price 37.49 | Shares 25,113
Proposed sale 16 Mar 2026
Value US$1,687,537.00 | Price 37.49 | Shares 45,013
Planned sale 12 Mar 2026
Value US$19,230.71 | Price 36.77 | Shares 523
Planned sale 12 Mar 2026
Value US$161,530.16 | Price 36.08 | Shares 4,477
Proposed sale 12 Mar 2026
Value US$184,900.00 | Price 36.98 | Shares 5,000
Planned sale 3 Mar 2026
Value US$266,304.71 | Price 39.67 | Shares 6,713
Planned sale 3 Mar 2026
Value US$119,010.00 | Price 39.67 | Shares 3,000
Proposed sale 3 Mar 2026
Value US$122,040.00 | Price 40.68 | Shares 3,000
Proposed sale 2 Mar 2026
Value US$280,000.00 | Price 41.18 | Shares 6,800
Proposed sale 2 Feb 2026
Value US$499,400.00 | Price 49.94 | Shares 10,000
Planned sale 5 Jan 2026
Value US$137,500.00 | Price 55.00 | Shares 2,500
Proposed sale 5 Jan 2026
Value US$116,825.00 | Price 46.73 | Shares 2,500
Proposed sale 2 Jan 2026
Value US$232,750.00 | Price 46.55 | Shares 5,000
Planned sale 1 Dec 2025
Value US$225,100.00 | Price 45.02 | Shares 5,000
Proposed sale 1 Dec 2025
Value US$227,800.00 | Price 45.56 | Shares 5,000
Planned sale 3 Nov 2025
Value US$4,327.00 | Price 43.27 | Shares 100
Planned sale 3 Nov 2025
Value US$208,985.00 | Price 42.65 | Shares 4,900
Proposed sale 3 Nov 2025
Value US$217,500.00 | Price 43.50 | Shares 5,000
Planned sale 1 Oct 2025
Value US$209,050.00 | Price 41.81 | Shares 5,000
Proposed sale 1 Oct 2025
Value US$208,250.00 | Price 41.65 | Shares 5,000
Planned sale 26 Sep 2025
Value US$180,000.00 | Price 45.00 | Shares 4,000
Proposed sale 26 Sep 2025
Value US$180,000.00 | Price 45.00 | Shares 4,000
Planned sale 26 Sep 2025
Value US$716,000.00 | Price 44.75 | Shares 16,000
Proposed sale 26 Sep 2025
Value US$574,240.00 | Price 35.89 | Shares 16,000
Planned sale 2 Sep 2025
Value US$160,500.00 | Price 32.10 | Shares 5,000
Proposed sale 2 Sep 2025
Value US$154,950.00 | Price 30.99 | Shares 5,000
Planned sale 22 Aug 2025
Value US$912,900.00 | Price 30.43 | Shares 30,000
Proposed sale 22 Aug 2025
Value US$882,000.00 | Price 29.40 | Shares 30,000
Planned sale 20 Aug 2025
Value US$189,436.56 | Price 29.18 | Shares 6,492
Proposed sale 20 Aug 2025
Value US$191,059.56 | Price 29.43 | Shares 6,492
Planned sale 12 Jun 2025
Value US$3,141,877.09 | Price 32.23 | Shares 97,483
Proposed sale 12 Jun 2025
Value US$3,151,625.39 | Price 32.33 | Shares 97,483
Planned sale 19 Mar 2025
Value US$10,135.53 | Price 34.83 | Shares 291
Planned sale 19 Mar 2025
Value US$187,217.43 | Price 34.17 | Shares 5,479
Planned sale 19 Mar 2025
Value US$30,476.25 | Price 34.83 | Shares 875
Planned sale 19 Mar 2025
Value US$562,540.71 | Price 34.17 | Shares 16,463
Planned sale 19 Mar 2025
Value US$12,573.63 | Price 34.83 | Shares 361
Planned sale 19 Mar 2025
Value US$232,390.17 | Price 34.17 | Shares 6,801
Planned sale 19 Mar 2025
Value US$4,423.41 | Price 34.83 | Shares 127
Planned sale 19 Mar 2025
Value US$81,597.96 | Price 34.17 | Shares 2,388
Planned sale 3 Feb 2025
Value US$195,350.00 | Price 39.07 | Shares 5,000
Proposed sale 3 Feb 2025
Value US$195,372.50 | Price 39.07 | Shares 5,000
Planned sale 3 Jan 2025
Value US$781,350.00 | Price 52.09 | Shares 15,000
Proposed sale 3 Jan 2025
Value US$781,323.00 | Price 52.09 | Shares 15,000
Planned sale 2 Dec 2024
Value US$575,700.00 | Price 57.57 | Shares 10,000
Proposed sale 2 Dec 2024
Value US$572,700.00 | Price 57.27 | Shares 10,000
Planned sale 22 Nov 2024
Value US$28,316.52 | Price 56.52 | Shares 501
Planned sale 3 Oct 2024
Value US$785,306.25 | Price 54.63 | Shares 14,375
Proposed sale 3 Oct 2024
Value US$785,322.06 | Price 54.63 | Shares 14,375
Planned sale 26 Sep 2024
Value US$1,277,750.00 | Price 51.11 | Shares 25,000
Proposed sale 26 Sep 2024
Value US$1,277,625.00 | Price 51.11 | Shares 25,000
Planned sale 10 Sep 2024
Value US$53,302.50 | Price 51.50 | Shares 1,035
Proposed sale 10 Sep 2024
Value US$53,300.74 | Price 51.50 | Shares 1,035
Planned sale 26 Aug 2024
Value US$159,570.00 | Price 53.19 | Shares 3,000
Proposed sale 26 Aug 2024
Value US$159,570.00 | Price 53.19 | Shares 3,000
Planned sale 12 Aug 2024
Value US$143,040.00 | Price 47.68 | Shares 3,000
Proposed sale 12 Aug 2024
Value US$143,049.90 | Price 47.68 | Shares 3,000
Planned sale 25 Jul 2024
Value US$160,290.00 | Price 53.43 | Shares 3,000
Planned sale 25 Jul 2024
Value US$160,290.00 | Price 53.43 | Shares 3,000
Planned sale 25 Jul 2024
Value US$1,026,737.28 | Price 53.88 | Shares 19,056
Planned sale 25 Jul 2024
Value US$1,026,737.28 | Price 53.88 | Shares 19,056
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-06-18 2026-06-17 PlS Planned sale
3.4
Okey Stephanie
Non-Executive Director
53,872 +12.2%
71.58
US$3,685,316 		53,872 +12.2% 71.58 US$3,685,316
2026-06-18 2026-06-17 PlS Planned sale
3.4
Okey Stephanie
Non-Executive Director
34,250 +46.6%
14.61
US$543,938 		34,250 +46.6% 14.61 US$543,938
2026-06-17 2026-06-17 PrS Proposed sale
3.4
STEPHANIE OKEY

Director

Non-Executive Director
74,636
179.24
US$4,676,618 		74,636 179.24 US$4,676,618
2026-05-04 2026-05-04 PrS Proposed sale
2.5
JEFF KNIGHT

Officer

Officer
9,485
39.02
US$370,105 		9,485 39.02 US$370,105
2026-04-14 2026-04-14 PrS Proposed sale
2.5
JEFF KNIGHT

Officer

Officer
20,900
38.66
US$807,994 		20,900 38.66 US$807,994
2026-04-13 2026-04-13 PrS Proposed sale
2.5
JEFF KNIGHT

Officer

Officer
4,434
39.44
US$174,877 		4,434 39.44 US$174,877
2026-04-10 2026-04-08 PlS Planned sale
2.5
Knight Jeff E.

Chief Dev. & Operating Officer

Officer
85,163 -44.7%
40.10
US$3,415,036 		85,163 -44.7% 40.10 US$3,415,036
2026-04-08 2026-04-08 PrS Proposed sale
2.5
JEFF KNIGHT

Officer

Officer
85,163
38.41
US$3,271,111 		85,163 38.41 US$3,271,111
2026-03-18 2026-03-18 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
24,756
37.89
US$938,005 		24,756 37.89 US$938,005
2026-03-18 2026-03-16 PlS Planned sale
2.3
Struthers Richard Scott

President & CEO

Executive Director
8,785 -2.1%
37.77
US$331,809 		8,785 -2.1% 37.77 US$331,809
2026-03-18 2026-03-16 PlS Planned sale
2.3
Struthers Richard Scott

President & CEO

Executive Director
13,196 -3.1%
37.11
US$489,704 		13,196 -3.1% 37.11 US$489,704
2026-03-18 2026-03-16 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
4,241 -3.0%
37.77
US$160,183 		4,241 -3.0% 37.77 US$160,183
2026-03-18 2026-03-16 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
6,371 -4.3%
37.11
US$236,428 		6,371 -4.3% 37.11 US$236,428
2026-03-16 2026-03-16 PrS Proposed sale
Stephen Betz

Officer

Officer
26,525
37.49
US$994,422 		26,525 37.49 US$994,422
2026-03-16 2026-03-16 PrS Proposed sale
2.5
Jeff Knight

Officer

Officer
25,113
37.49
US$941,486 		25,113 37.49 US$941,486
2026-03-16 2026-03-16 PrS Proposed sale
2.3
Richard Scott Struthers

Director; Officer

Executive Director
45,013
37.49
US$1,687,537 		45,013 37.49 US$1,687,537
2026-03-13 2026-03-12 PlS Planned sale
1.4
Vivaldi Coelho Rogerio
Non-Executive Director
523 -3.1%
36.77
US$19,231 		523 -3.1% 36.77 US$19,231
2026-03-13 2026-03-12 PlS Planned sale
1.4
Vivaldi Coelho Rogerio
Non-Executive Director
4,477 -21.0%
36.08
US$161,530 		4,477 -21.0% 36.08 US$161,530
2026-03-12 2026-03-12 PrS Proposed sale
1.4
ROGERIO VIVALDI COELHO

Director

Non-Executive Director
5,000
36.98
US$184,900 		5,000 36.98 US$184,900
2026-03-04 2026-03-03 PlS Planned sale
3.8
Schilke Tobin

Chief Financial Officer

Officer
6,713 -7.9%
39.67
US$266,305 		6,713 -7.9% 39.67 US$266,305
2026-03-04 2026-03-03 PlS Planned sale
3.4
Okey Stephanie
Non-Executive Director
3,000 -18.4%
39.67
US$119,010 		3,000 -18.4% 39.67 US$119,010
2026-03-03 2026-03-03 PrS Proposed sale
3.4
STEPHANIE S OKEY

Director

Non-Executive Director
3,000
40.68
US$122,040 		3,000 40.68 US$122,040
2026-03-02 2026-03-02 PrS Proposed sale
3.8
Tobin Schilke

Officer

Officer
6,800
41.18
US$280,000 		6,800 41.18 US$280,000
2026-02-02 2026-02-02 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
10,000
49.94
US$499,400 		10,000 49.94 US$499,400
2026-01-07 2026-01-05 PlS Planned sale
Kalofonos Isabel

Chief Commercial Officer

Officer
2,500 -75.0%
55.00
US$137,500 		2,500 -75.0% 55.00 US$137,500
2026-01-05 2026-01-05 PrS Proposed sale
ISABEL KALOFONOS

Officer

Officer
2,500
46.73
US$116,825 		2,500 46.73 US$116,825
2026-01-02 2026-01-02 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
5,000
46.55
US$232,750 		5,000 46.55 US$232,750
2025-12-03 2025-12-01 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
5,000 -7.0%
45.02
US$225,100 		5,000 -7.0% 45.02 US$225,100
2025-12-01 2025-12-01 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
5,000
45.56
US$227,800 		5,000 45.56 US$227,800
2025-11-05 2025-11-03 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
100 -0.2%
43.27
US$4,327 		100 -0.2% 43.27 US$4,327
2025-11-05 2025-11-03 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
4,900 -6.9%
42.65
US$208,985 		4,900 -6.9% 42.65 US$208,985
2025-11-03 2025-11-03 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
5,000
43.50
US$217,500 		5,000 43.50 US$217,500
2025-10-03 2025-10-01 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
5,000 -7.0%
41.81
US$209,050 		5,000 -7.0% 41.81 US$209,050
2025-10-01 2025-10-01 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
5,000
41.65
US$208,250 		5,000 41.65 US$208,250
2025-09-30 2025-09-26 PlS Planned sale
2.3
Struthers Richard Scott

President & CEO

Executive Director
4,000 -3.6%
45.00
US$180,000 		4,000 -3.6% 45.00 US$180,000
2025-09-30 2025-09-26 PlS Planned sale
3.8
Fust Matthew K
Non-Executive Director
16,000 -41.2%
44.75
US$716,000 		16,000 -41.2% 44.75 US$716,000
2025-09-26 2025-09-26 PrS Proposed sale
2.3
Struthers Richard Scott

Officer; Director

Executive Director
4,000
45.00
US$180,000 		4,000 45.00 US$180,000
2025-09-26 2025-09-26 PrS Proposed sale
3.8
MATTHEW K FUST

Director

Non-Executive Director
16,000
35.89
US$574,240 		16,000 35.89 US$574,240
2025-09-04 2025-09-02 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
5,000 -4.9%
32.10
US$160,500 		5,000 -4.9% 32.10 US$160,500
2025-09-02 2025-09-02 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
5,000
30.99
US$154,950 		5,000 30.99 US$154,950
2025-08-26 2025-08-22 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
30,000 -31.2%
30.43
US$912,900 		30,000 -31.2% 30.43 US$912,900
2025-08-22 2025-08-22 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
30,000
29.40
US$882,000 		30,000 29.40 US$882,000
2025-08-21 2025-08-20 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
6,492 -8.9%
29.18
US$189,437 		6,492 -8.9% 29.18 US$189,437
2025-08-20 2025-08-20 PrS Proposed sale
1.9
DANA PIZZUTI

Officer

Officer
6,492
29.43
US$191,060 		6,492 29.43 US$191,060
2025-06-16 2025-06-12 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
97,483 -49.4%
32.23
US$3,141,877 		97,483 -49.4% 32.23 US$3,141,877
2025-06-12 2025-06-12 PrS Proposed sale
STEPHEN BETZ

Officer

Officer
97,483
32.33
US$3,151,625 		97,483 32.33 US$3,151,625
2025-03-21 2025-03-19 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
291 -0.3%
34.83
US$10,136 		291 -0.3% 34.83 US$10,136
2025-03-21 2025-03-19 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
5,479 -4.8%
34.17
US$187,217 		5,479 -4.8% 34.17 US$187,217
2025-03-21 2025-03-19 PlS Planned sale
2.3
Struthers Richard Scott

President & CEO

Executive Director
875 -0.3%
34.83
US$30,476 		875 -0.3% 34.83 US$30,476
2025-03-21 2025-03-19 PlS Planned sale
2.3
Struthers Richard Scott

President & CEO

Executive Director
16,463 -4.8%
34.17
US$562,541 		16,463 -4.8% 34.17 US$562,541
2025-03-21 2025-03-19 PlS Planned sale
2.5
Knight Jeff E.

Chief Operating Officer

Officer
361 -0.4%
34.83
US$12,574 		361 -0.4% 34.83 US$12,574
2025-03-21 2025-03-19 PlS Planned sale
2.5
Knight Jeff E.

Chief Operating Officer

Officer
6,801 -7.2%
34.17
US$232,390 		6,801 -7.2% 34.17 US$232,390
2025-03-21 2025-03-19 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
127 -0.2%
34.83
US$4,423 		127 -0.2% 34.83 US$4,423
2025-03-21 2025-03-19 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
2,388 -3.2%
34.17
US$81,598 		2,388 -3.2% 34.17 US$81,598
2025-02-05 2025-02-03 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
5,000 -13.6%
39.07
US$195,350 		5,000 -13.6% 39.07 US$195,350
2025-02-03 2025-02-03 PrS Proposed sale
1.9
DANA J PIZZUTI

Officer

Officer
5,000
39.07
US$195,372 		5,000 39.07 US$195,372
2025-01-07 2025-01-03 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
15,000 -33.9%
52.09
US$781,350 		15,000 -33.9% 52.09 US$781,350
2025-01-03 2025-01-03 PrS Proposed sale
1.9
DANA J PIZZUTI

Officer

Officer
15,000
52.09
US$781,323 		15,000 52.09 US$781,323
2024-12-04 2024-12-02 PlS Planned sale
2.3
Struthers Richard Scott

President & CEO

Executive Director
10,000 -9.1%
57.57
US$575,700 		10,000 -9.1% 57.57 US$575,700
2024-12-02 2024-12-02 PrS Proposed sale
2.3
Struthers Richard Scott

Officer

Officer
10,000
57.27
US$572,700 		10,000 57.27 US$572,700
2024-11-26 2024-11-22 PlS Planned sale
2.5
Knight Jeff E.

Chief Operating Officer

Officer
501 -1.0%
56.52
US$28,317 		501 -1.0% 56.52 US$28,317
2024-10-07 2024-10-03 PlS Planned sale
1.9
Pizzuti Dana

Chief Med and Dev Officer

Officer
14,375 -33.5%
54.63
US$785,306 		14,375 -33.5% 54.63 US$785,306
2024-10-03 2024-10-03 PrS Proposed sale
1.9
DANA J PIZZUTI

Officer

Officer
14,375
54.63
US$785,322 		14,375 54.63 US$785,322
2024-09-30 2024-09-26 PlS Planned sale
1.5
Wilson Marc

CFO

Officer
25,000 -18.4%
51.11
US$1,277,750 		25,000 -18.4% 51.11 US$1,277,750
2024-09-26 2024-09-26 PrS Proposed sale
1.5
MARC WILSON

Officer

Officer
25,000
51.11
US$1,277,625 		25,000 51.11 US$1,277,625
2024-09-12 2024-09-10 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
1,035 -1.5%
51.50
US$53,302 		1,035 -1.5% 51.50 US$53,302
2024-09-10 2024-09-10 PrS Proposed sale
Betz Stephen F.

Officer; Co-Founder

Officer
1,035
51.50
US$53,301 		1,035 51.50 US$53,301
2024-08-28 2024-08-26 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
3,000 -4.1%
53.19
US$159,570 		3,000 -4.1% 53.19 US$159,570
2024-08-26 2024-08-26 PrS Proposed sale
Betz Stephen F.

Officer; Co-Founder

Officer
3,000
53.19
US$159,570 		3,000 53.19 US$159,570
2024-08-14 2024-08-12 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
3,000 -4.0%
47.68
US$143,040 		3,000 -4.0% 47.68 US$143,040
2024-08-12 2024-08-12 PrS Proposed sale
Betz Stephen F.

Officer; Co-Founder

Officer
3,000
47.68
US$143,050 		3,000 47.68 US$143,050
2024-07-26 2024-07-25 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
3,000 -3.8%
53.43
US$160,290 		3,000 -3.8% 53.43 US$160,290
2024-07-26 2024-07-25 PlS Planned sale
Betz Stephen F.

Chief Scientific Officer

Officer
3,000 -3.8%
53.43
US$160,290 		3,000 -3.8% 53.43 US$160,290
2024-07-26 2024-07-25 PlS Planned sale
1.5
Wilson Marc

CFO

Officer
19,056 -14.6%
53.88
US$1,026,737 		19,056 -14.6% 53.88 US$1,026,737
2024-07-26 2024-07-25 PlS Planned sale
1.5
Wilson Marc

CFO

Officer
19,056 -14.6%
53.88
US$1,026,737 		19,056 -14.6% 53.88 US$1,026,737
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