Kalofonos Isabel

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2026-01-07	2026-01-05	Crinetics Pharmaceuticals Inc (CRNX)	PlS Planned sale	50,085 +1.9% 293.04 US$4,024,723	50,085 +1.9%	293.04	US$4,024,723
2026-01-05	2026-01-05	Crinetics Pharmaceuticals Inc (CRNX)	PrS Proposed sale	24,197 23.77 US$2,828,191	24,197	23.77	US$2,828,191