United States Biotechnology & Medical Research

Centessa Pharmaceuticals PLC (CNTA)

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Over the last 90 days, Centessa Pharmaceuticals PLC has seen significant insider selling activity, totaling over $18 million. Notably, Chief People Officer Karen M. Anderson and Chief Business Officer Gregory M. Weinhoff have engaged in multiple planned and proposed sales. No insider purchases were recorded during this period. The stock has experienced a substantial price increase of 46.1% over the past 90 days.

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Ticker: CNTA Exchange: NSM

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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Trades

Anderson Karen M.

Chief People Officer

2 sales — total 2,393,671 USD

Planned sale 26 Mar 2026

Value US$195,250.11 | Price 383.85 | Shares 3,058

Proposed sale 26 Mar 2026

Value US$3,522,331.69 | Price 117.82 | Shares 15,888

Weinhoff Gregory M

Chief Business Officer

2 sales — total 1,395,484 USD

Planned sale 26 Mar 2026

Value US$898,730.73 | Price 212.22 | Shares 93,494

Proposed sale 26 Mar 2026

Value US$2,131,765.40 | Price 387.64 | Shares 60,490

Anderson Karen M.

Chief People Officer

2 sales — total 563,213 USD

Planned sale 17 Mar 2026

Value US$282,210.31 | Price 28.10 | Shares 10,043

Proposed sale 17 Mar 2026

Value US$281,003.14 | Price 27.98 | Shares 10,043

Anderson Karen M.

Chief People Officer

2 sales — total 3,653,939 USD

Planned sale 16 Mar 2026

Value US$1,826,969.27 | Price 28.21 | Shares 64,768

Proposed sale 16 Mar 2026

Value US$1,826,969.27 | Price 28.21 | Shares 64,768

Weinhoff Gregory M

Chief Business Officer

3 sales — total 3,920,624 USD

Planned sale 13 Mar 2026

Value US$324,336.05 | Price 27.16 | Shares 11,943

Planned sale 13 Mar 2026

Value US$1,602,795.00 | Price 26.17 | Shares 61,253

Proposed sale 13 Mar 2026

Value US$1,993,493.06 | Price 27.24 | Shares 73,196

Anderson Karen M.

Chief People Officer

3 sales — total 6,254,623 USD

Planned sale 13 Mar 2026

Value US$327,438.63 | Price 27.13 | Shares 12,068

Planned sale 13 Mar 2026

Value US$2,823,234.13 | Price 26.15 | Shares 107,961

Proposed sale 13 Mar 2026

Value US$3,103,949.94 | Price 25.86 | Shares 120,029

HUSSAIN IQBAL J

Chief Legal Officer

2 sales — total 1,959,313 USD

Sale 2 Feb 2026

Value US$979,656.60 | Price 25.15 | Shares 38,951

Sale 2 Feb 2026

Value US$979,656.60 | Price 25.15 | Shares 38,951

HUSSAIN IQBAL J

Chief Legal Officer

1 sale — total 25,261 USD

Sale 30 Jan 2026

Value US$25,261.01 | Price 25.01 | Shares 1,010

Iqbal Hussain

Officer

1 sale — total 1,019,005 USD

Proposed sale 30 Jan 2026

Value US$1,019,005.00 | Price 25.50 | Shares 39,961

Saurabh Saha

Former Officer

1 sale — total 52,601,000 USD

Proposed sale 21 Jan 2026

Value US$52,601,000.00 | Price 22.87 | Shares 2,300,000

Saurabh Saha

Previous Officer

1 sale — total 60,750,000 USD

Proposed sale 2 Jan 2026

Value US$60,750,000.00 | Price 24.30 | Shares 2,500,000

Accardi Mario Alberto

Officer

3 sales — total 581,289 USD

Proposed sale 9 Dec 2025

Value US$293,000.00 | Price 29.30 | Shares 10,000

Planned sale 9 Dec 2025

Value US$75,005.37 | Price 29.21 | Shares 2,568

Planned sale 9 Dec 2025

Value US$213,283.54 | Price 28.70 | Shares 7,432

Accardi Mario Alberto

Officer

2 sales — total 600,000 USD

Proposed sale 8 Dec 2025

Value US$300,000.00 | Price 30.00 | Shares 10,000

Planned sale 8 Dec 2025

Value US$300,000.00 | Price 30.00 | Shares 10,000

Bush Tia L

Chief Technology & Quality Ofc

2 sales — total 2,240,000 USD

Planned sale 17 Nov 2025

Value US$1,120,000.00 | Price 28.00 | Shares 40,000

Proposed sale 17 Nov 2025

Value US$1,120,000.00 | Price 28.00 | Shares 40,000

HUSSAIN IQBAL J

General Counsel

2 sales — total 332,275 USD

Planned sale 17 Nov 2025

Value US$165,835.20 | Price 27.64 | Shares 6,000

Proposed sale 17 Nov 2025

Value US$166,440.00 | Price 27.74 | Shares 6,000

Bush Tia L

Chief Technology & Quality Ofc

2 sales — total 2,080,000 USD

Planned sale 12 Nov 2025

Value US$1,040,000.00 | Price 26.00 | Shares 40,000

Proposed sale 12 Nov 2025

Value US$1,040,000.00 | Price 26.00 | Shares 40,000

Accardi Mario Alberto

Officer

3 sales — total 600,000 USD

Proposed sale 27 Oct 2025

Value US$200,000.00 | Price 25.00 | Shares 8,000

Proposed sale 27 Oct 2025

Value US$200,000.00 | Price 25.00 | Shares 8,000

Planned sale 27 Oct 2025

Value US$200,000.00 | Price 25.00 | Shares 8,000

HUSSAIN IQBAL J

General Counsel

2 sales — total 270,099 USD

Planned sale 15 Oct 2025

Value US$134,439.00 | Price 22.41 | Shares 6,000

Proposed sale 15 Oct 2025

Value US$135,660.00 | Price 22.61 | Shares 6,000

Bush Tia L

Officer

2 sales — total 1,680,000 USD

Proposed sale 24 Sep 2025

Value US$840,000.00 | Price 24.00 | Shares 35,000

Planned sale 24 Sep 2025

Value US$840,000.00 | Price 24.00 | Shares 35,000

Accardi Mario Alberto

Officer

3 sales — total 355,121 USD

Proposed sale 16 Sep 2025

Value US$180,274.32 | Price 22.06 | Shares 8,172

Planned sale 16 Sep 2025

Value US$16,339.80 | Price 22.02 | Shares 742

Planned sale 16 Sep 2025

Value US$158,506.42 | Price 21.33 | Shares 7,430

HUSSAIN IQBAL J

Officer

2 sales — total 261,961 USD

Proposed sale 15 Sep 2025

Value US$130,860.00 | Price 21.81 | Shares 6,000

Planned sale 15 Sep 2025

Value US$131,100.60 | Price 21.85 | Shares 6,000

Bush Tia L

Chief Technology & Quality Ofc

2 sales — total 1,100,000 USD

Planned sale 10 Sep 2025

Value US$550,000.00 | Price 22.00 | Shares 25,000

Proposed sale 10 Sep 2025

Value US$550,000.00 | Price 22.00 | Shares 25,000

HUSSAIN IQBAL J

General Counsel

2 sales — total 880,000 USD

Planned sale 10 Sep 2025

Value US$440,000.00 | Price 22.00 | Shares 20,000

Proposed sale 10 Sep 2025

Value US$440,000.00 | Price 22.00 | Shares 20,000

Bush Tia L

Chief Technology & Quality Ofc

2 sales — total 991,680 USD

Planned sale 9 Sep 2025

Value US$495,840.00 | Price 20.00 | Shares 24,792

Proposed sale 9 Sep 2025

Value US$495,840.00 | Price 20.00 | Shares 24,792

HUSSAIN IQBAL J

General Counsel

2 sales — total 800,204 USD

Planned sale 9 Sep 2025

Value US$400,102.00 | Price 20.01 | Shares 20,000

Proposed sale 9 Sep 2025

Value US$400,102.00 | Price 20.01 | Shares 20,000

Accardi Mario Alberto

President, Orexin Program

2 sales — total 280,000 USD

Planned sale 9 Sep 2025

Value US$140,000.00 | Price 20.00 | Shares 7,000

Proposed sale 9 Sep 2025

Value US$140,000.00 | Price 20.00 | Shares 7,000

HUSSAIN IQBAL J

Officer

2 sales — total 206,760 USD

Proposed sale 15 Aug 2025

Value US$103,380.00 | Price 17.23 | Shares 6,000

Planned sale 15 Aug 2025

Value US$103,380.00 | Price 17.23 | Shares 6,000

Accardi Mario Alberto

Officer

1 sale — total 127,909 USD

Proposed sale 29 Jul 2025

Value US$127,909.14 | Price 15.37 | Shares 8,322

Weinhoff Gregory M

Officer

2 sales — total 311,196 USD

Proposed sale 25 Jul 2025

Value US$155,598.00 | Price 15.56 | Shares 10,000

Planned sale 25 Jul 2025

Value US$155,598.00 | Price 15.56 | Shares 10,000

SAHA SAURABH

Officer; CEO

2 sales — total 1,755,050 USD

Proposed sale 21 Jul 2025

Value US$879,450.00 | Price 15.99 | Shares 55,000

Planned sale 21 Jul 2025

Value US$875,600.00 | Price 15.92 | Shares 55,000

CHAO DAVID M

Officer

1 sale — total 80,000 USD

Proposed sale 17 Jul 2025

Value US$80,000.00 | Price 16.00 | Shares 5,000

CHAO DAVID M

Officer

1 sale — total 149,183 USD

Proposed sale 15 Jul 2025

Value US$149,182.50 | Price 14.92 | Shares 10,000

HUSSAIN IQBAL J

General Counsel

2 sales — total 179,134 USD

Planned sale 15 Jul 2025

Value US$89,566.80 | Price 14.93 | Shares 6,000

Proposed sale 15 Jul 2025

Value US$89,566.80 | Price 14.93 | Shares 6,000

Weinhoff Gregory M

Officer

2 sales — total 278,642 USD

Proposed sale 25 Jun 2025

Value US$140,000.00 | Price 14.00 | Shares 10,000

Planned sale 25 Jun 2025

Value US$138,642.00 | Price 13.86 | Shares 10,000

Accardi Mario Alberto

Officer

2 sales — total 420,000 USD

Proposed sale 24 Jun 2025

Value US$210,000.00 | Price 14.00 | Shares 15,000

Planned sale 24 Jun 2025

Value US$210,000.00 | Price 14.00 | Shares 15,000

HUSSAIN IQBAL J

General Counsel

2 sales — total 336,437 USD

Planned sale 24 Jun 2025

Value US$168,218.40 | Price 14.02 | Shares 12,000

Proposed sale 24 Jun 2025

Value US$168,218.40 | Price 14.02 | Shares 12,000

CHAO DAVID M

Officer

1 sale — total 128,650 USD

Proposed sale 20 Jun 2025

Value US$128,650.00 | Price 12.87 | Shares 10,000

SAHA SAURABH

Officer; CEO

2 sales — total 1,402,401 USD

Proposed sale 20 Jun 2025

Value US$707,575.00 | Price 12.87 | Shares 55,000

Planned sale 20 Jun 2025

Value US$694,826.00 | Price 12.63 | Shares 55,000

Weinhoff Gregory M

Officer

2 sales — total 256,450 USD

Proposed sale 27 May 2025

Value US$128,225.00 | Price 12.82 | Shares 10,000

Planned sale 27 May 2025

Value US$128,225.00 | Price 12.82 | Shares 10,000

Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Insider and/or position	Nb. shares Price Value	Number of shares	Price	Value
2026-03-27	2026-03-26	PlS Planned sale	Anderson Karen M. Chief People Officer Officer	3,058 -28.2% 383.85 US$195,250	3,058 -28.2%	383.85	US$195,250
2026-03-26	2026-03-26	PlS Planned sale	2.6 Weinhoff Gregory M Chief Business Officer Officer	93,494 +5.0% 212.22 US$898,731	93,494 +5.0%	212.22	US$898,731
2026-03-26	2026-03-26	PrS Proposed sale	2.6 Weinhoff Gregory M Officer Officer	60,490 387.64 US$2,131,765	60,490	387.64	US$2,131,765
2026-03-26	2026-03-26	PrS Proposed sale	Anderson Karen M. Officer Officer	41,076 28.15 US$1,156,289	41,076	28.15	US$1,156,289
2026-03-18	2026-03-17	PlS Planned sale	Anderson Karen M. Chief People Officer Officer	10,043 -13.9% 28.10 US$282,210	10,043 -13.9%	28.10	US$282,210
2026-03-17	2026-03-17	PrS Proposed sale	Anderson Karen M. Officer Officer	10,043 27.98 US$281,003	10,043	27.98	US$281,003
2026-03-18	2026-03-16	PlS Planned sale	Anderson Karen M. Chief People Officer Officer	64,768 -51.1% 28.21 US$1,826,969	64,768 -51.1%	28.21	US$1,826,969
2026-03-16	2026-03-16	PrS Proposed sale	Anderson Karen M. Officer Officer	64,768 28.21 US$1,826,969	64,768	28.21	US$1,826,969
2026-03-13	2026-03-13	PlS Planned sale	2.6 Weinhoff Gregory M Chief Business Officer Officer	11,943 -15.3% 27.16 US$324,336	11,943 -15.3%	27.16	US$324,336
2026-03-13	2026-03-13	PlS Planned sale	2.6 Weinhoff Gregory M Chief Business Officer Officer	61,253 -44.0% 26.17 US$1,602,795	61,253 -44.0%	26.17	US$1,602,795
2026-03-13	2026-03-13	PlS Planned sale	Anderson Karen M. Chief People Officer Officer	12,068 -16.3% 27.13 US$327,439	12,068 -16.3%	27.13	US$327,439
2026-03-13	2026-03-13	PlS Planned sale	Anderson Karen M. Chief People Officer Officer	107,961 -59.3% 26.15 US$2,823,234	107,961 -59.3%	26.15	US$2,823,234
2026-03-13	2026-03-13	PrS Proposed sale	Anderson Karen M. Officer Officer	120,029 25.86 US$3,103,950	120,029	25.86	US$3,103,950
2026-03-13	2026-03-13	PrS Proposed sale	2.6 Weinhoff Gregory M Officer Officer	73,196 27.24 US$1,993,493	73,196	27.24	US$1,993,493
2026-02-03	2026-02-02	S Sale	1.5 HUSSAIN IQBAL J Chief Legal Officer Officer	38,951 -40.3% 25.15 US$979,657	38,951 -40.3%	25.15	US$979,657
2026-02-03	2026-02-02	S Sale	1.5 HUSSAIN IQBAL J Chief Legal Officer Officer	38,951 -40.3% 25.15 US$979,657	38,951 -40.3%	25.15	US$979,657
2026-02-03	2026-01-30	S Sale	1.5 HUSSAIN IQBAL J Chief Legal Officer Officer	1,010 -1.0% 25.01 US$25,261	1,010 -1.0%	25.01	US$25,261
2026-01-30	2026-01-30	PrS Proposed sale	1.5 Iqbal Hussain Officer Officer	39,961 25.50 US$1,019,005	39,961	25.50	US$1,019,005
2026-01-21	2026-01-21	PrS Proposed sale	2.1 Saurabh Saha Former Officer Officer	2,300,000 22.87 US$52,601,000	2,300,000	22.87	US$52,601,000
2026-01-02	2026-01-02	PrS Proposed sale	2.1 Saurabh Saha Previous Officer Officer	2,500,000 24.30 US$60,750,000	2,500,000	24.30	US$60,750,000
2025-12-09	2025-12-09	PrS Proposed sale	Accardi Mario Alberto Officer Officer	10,000 29.30 US$293,000	10,000	29.30	US$293,000
2025-12-09	2025-12-09	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	2,568 -1.4% 29.21 US$75,005	2,568 -1.4%	29.21	US$75,005
2025-12-09	2025-12-09	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	7,432 -3.9% 28.70 US$213,284	7,432 -3.9%	28.70	US$213,284
2025-12-08	2025-12-08	PrS Proposed sale	Accardi Mario Alberto Officer Officer	10,000 30.00 US$300,000	10,000	30.00	US$300,000
2025-12-08	2025-12-08	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	10,000 -5.0% 30.00 US$300,000	10,000 -5.0%	30.00	US$300,000
2025-11-18	2025-11-17	PlS Planned sale	1.6 Bush Tia L Chief Technology & Quality Ofc Officer	40,000 -24.8% 28.00 US$1,120,000	40,000 -24.8%	28.00	US$1,120,000
2025-11-18	2025-11-17	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	6,000 -5.4% 27.64 US$165,835	6,000 -5.4%	27.64	US$165,835
2025-11-17	2025-11-17	PrS Proposed sale	1.6 Bush Tia L Officer Officer	40,000 28.00 US$1,120,000	40,000	28.00	US$1,120,000
2025-11-17	2025-11-17	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	6,000 27.74 US$166,440	6,000	27.74	US$166,440
2025-11-13	2025-11-12	PlS Planned sale	1.6 Bush Tia L Chief Technology & Quality Ofc Officer	40,000 -24.8% 26.00 US$1,040,000	40,000 -24.8%	26.00	US$1,040,000
2025-11-12	2025-11-12	PrS Proposed sale	1.6 Bush Tia L Officer Officer	40,000 26.00 US$1,040,000	40,000	26.00	US$1,040,000
2025-10-27	2025-10-27	PrS Proposed sale	Accardi Mario Alberto Officer Officer	8,000 25.00 US$200,000	8,000	25.00	US$200,000
2025-10-27	2025-10-27	PrS Proposed sale	Accardi Mario Alberto Officer Officer	8,000 25.00 US$200,000	8,000	25.00	US$200,000
2025-10-27	2025-10-27	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	8,000 -4.0% 25.00 US$200,000	8,000 -4.0%	25.00	US$200,000
2025-10-16	2025-10-15	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	6,000 -5.4% 22.41 US$134,439	6,000 -5.4%	22.41	US$134,439
2025-10-15	2025-10-15	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	6,000 22.61 US$135,660	6,000	22.61	US$135,660
2025-09-24	2025-09-24	PrS Proposed sale	1.6 Bush Tia L Officer Officer	35,000 24.00 US$840,000	35,000	24.00	US$840,000
2025-09-24	2025-09-24	PlS Planned sale	1.6 Bush Tia L Chief Technology & Quality Ofc Officer	35,000 -22.4% 24.00 US$840,000	35,000 -22.4%	24.00	US$840,000
2025-09-16	2025-09-16	PrS Proposed sale	Accardi Mario Alberto Officer Officer	8,172 22.06 US$180,274	8,172	22.06	US$180,274
2025-09-16	2025-09-16	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	742 -0.4% 22.02 US$16,340	742 -0.4%	22.02	US$16,340
2025-09-16	2025-09-16	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	7,430 -3.6% 21.33 US$158,506	7,430 -3.6%	21.33	US$158,506
2025-09-15	2025-09-15	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	6,000 21.81 US$130,860	6,000	21.81	US$130,860
2025-09-15	2025-09-15	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	6,000 -5.4% 21.85 US$131,101	6,000 -5.4%	21.85	US$131,101
2025-09-11	2025-09-10	PlS Planned sale	1.6 Bush Tia L Chief Technology & Quality Ofc Officer	25,000 -17.1% 22.00 US$550,000	25,000 -17.1%	22.00	US$550,000
2025-09-11	2025-09-10	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	20,000 -16.0% 22.00 US$440,000	20,000 -16.0%	22.00	US$440,000
2025-09-10	2025-09-10	PrS Proposed sale	1.6 Bush Tia L Officer Officer	25,000 22.00 US$550,000	25,000	22.00	US$550,000
2025-09-10	2025-09-10	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	20,000 22.00 US$440,000	20,000	22.00	US$440,000
2025-09-11	2025-09-09	PlS Planned sale	1.6 Bush Tia L Chief Technology & Quality Ofc Officer	24,792 -16.9% 20.00 US$495,840	24,792 -16.9%	20.00	US$495,840
2025-09-11	2025-09-09	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	20,000 -16.0% 20.01 US$400,102	20,000 -16.0%	20.01	US$400,102
2025-09-11	2025-09-09	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	7,000 -3.3% 20.00 US$140,000	7,000 -3.3%	20.00	US$140,000
2025-09-09	2025-09-09	PrS Proposed sale	1.6 Bush Tia L Officer Officer	24,792 20.00 US$495,840	24,792	20.00	US$495,840
2025-09-09	2025-09-09	PrS Proposed sale	Accardi Mario Alberto Officer Officer	7,000 20.00 US$140,000	7,000	20.00	US$140,000
2025-09-09	2025-09-09	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	20,000 20.01 US$400,102	20,000	20.01	US$400,102
2025-08-15	2025-08-15	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	6,000 17.23 US$103,380	6,000	17.23	US$103,380
2025-08-15	2025-08-15	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	6,000 -5.4% 17.23 US$103,380	6,000 -5.4%	17.23	US$103,380
2025-07-29	2025-07-29	PrS Proposed sale	Accardi Mario Alberto Officer Officer	8,322 15.37 US$127,909	8,322	15.37	US$127,909
2025-07-25	2025-07-25	PrS Proposed sale	2.6 Weinhoff Gregory M Officer Officer	10,000 15.56 US$155,598	10,000	15.56	US$155,598
2025-07-25	2025-07-25	PlS Planned sale	2.6 Weinhoff Gregory M Chief Business Officer Officer	10,000 -7.6% 15.56 US$155,598	10,000 -7.6%	15.56	US$155,598
2025-07-21	2025-07-21	PrS Proposed sale	2.1 SAHA SAURABH Officer; CEO Officer	55,000 15.99 US$879,450	55,000	15.99	US$879,450
2025-07-21	2025-07-21	PlS Planned sale	2.1 SAHA SAURABH Chief Executive Officer Executive Director	55,000 -19.9% 15.92 US$875,600	55,000 -19.9%	15.92	US$875,600
2025-07-17	2025-07-17	PrS Proposed sale	2.6 CHAO DAVID M Officer Officer	5,000 16.00 US$80,000	5,000	16.00	US$80,000
2025-07-17	2025-07-15	PrS Proposed sale	2.6 CHAO DAVID M Officer Officer	10,000 14.92 US$149,182	10,000	14.92	US$149,182
2025-07-17	2025-07-15	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	6,000 -5.4% 14.93 US$89,567	6,000 -5.4%	14.93	US$89,567
2025-07-15	2025-07-15	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	6,000 14.93 US$89,567	6,000	14.93	US$89,567
2025-06-25	2025-06-25	PrS Proposed sale	2.6 Weinhoff Gregory M Officer Officer	10,000 14.00 US$140,000	10,000	14.00	US$140,000
2025-06-25	2025-06-25	PlS Planned sale	2.6 Weinhoff Gregory M Chief Business Officer Officer	10,000 -7.6% 13.86 US$138,642	10,000 -7.6%	13.86	US$138,642
2025-06-25	2025-06-24	PrS Proposed sale	Accardi Mario Alberto Officer Officer	15,000 14.00 US$210,000	15,000	14.00	US$210,000
2025-06-25	2025-06-24	PlS Planned sale	Accardi Mario Alberto President, Orexin Program Officer	15,000 -6.5% 14.00 US$210,000	15,000 -6.5%	14.00	US$210,000
2025-06-25	2025-06-24	PlS Planned sale	1.5 HUSSAIN IQBAL J General Counsel Officer	12,000 -10.2% 14.02 US$168,218	12,000 -10.2%	14.02	US$168,218
2025-06-24	2025-06-24	PrS Proposed sale	1.5 HUSSAIN IQBAL J Officer Officer	12,000 14.02 US$168,218	12,000	14.02	US$168,218
2025-06-20	2025-06-20	PrS Proposed sale	2.6 CHAO DAVID M Officer Officer	10,000 12.87 US$128,650	10,000	12.87	US$128,650
2025-06-20	2025-06-20	PrS Proposed sale	2.1 SAHA SAURABH Officer; CEO Officer	55,000 12.87 US$707,575	55,000	12.87	US$707,575
2025-06-20	2025-06-20	PlS Planned sale	2.1 SAHA SAURABH Chief Executive Officer Executive Director	55,000 -19.9% 12.63 US$694,826	55,000 -19.9%	12.63	US$694,826
2025-05-27	2025-05-27	PrS Proposed sale	2.6 Weinhoff Gregory M Officer Officer	10,000 12.82 US$128,225	10,000	12.82	US$128,225
2025-05-27	2025-05-27	PlS Planned sale	2.6 Weinhoff Gregory M Chief Business Officer Officer	10,000 -7.6% 12.82 US$128,225	10,000 -7.6%	12.82	US$128,225

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