United States Biotechnology & Medical Research

Cabaletta Bio Inc (CABA)

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Cabaletta Bio Inc. saw significant insider buying on January 21, 2026, involving multiple executives including the CEO and Chief Medical Officer. These purchases represent the most recent activity recorded. Prior to this, historical filings from 2023 and 2024 primarily reflected planned sales by leadership. No further transactions occurred within the last three months.
Ticker: CABA Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Cabaletta Bio Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
4.0
Simon Mark Non-Executive Director
Transaction date
Purchase
Price
31.09
Quantity 31,698 +34.7%
Value US$463,525
3.3
Chang David J. Chief Medical Officer Officer
Transaction date
Purchase
Price
333.54
Quantity 61,573 +0.6%
Value US$3,373,800
4.0
Binder Gwendolyn President, Science & Tech. Officer
Transaction date
Purchase
Price
315.77
Quantity 36,097 -42.5%
Value US$963,707
3.3
Gerard Michael General Counsel Officer
Transaction date
Purchase
Price
2.27
Quantity 6,600 +inf%
Value US$14,979
3.3
Gavel Steve Chief Commercial Officer Officer
Transaction date
Purchase
Price
2.27
Quantity 22,170 +inf%
Value US$50,215
3.7
Tomasello Shawn Non-Executive Director
Transaction date
Purchase
Price
2.21
Quantity 22,725 +inf%
Value US$50,322
4.0
Nichtberger Steven President & CEO Executive Director
Transaction date
Purchase
Price
2.24
Quantity 45,000 +4.6%
Value US$100,778
4.0
Bollard Catherine Non-Executive Director
Transaction date
Purchase
Price
2.27
Quantity 4,405 +440.5%
Value US$9,982
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
20.33
Quantity 700 -3.4%
Value US$14,229
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
19.54
Quantity 10,300 -33.2%
Value US$201,210
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
22.22
Quantity 3,132 -13.5%
Value US$69,593
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
21.76
Quantity 7,868 -25.4%
Value US$171,196
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
18.02
Quantity 7,458 -27.2%
Value US$134,405
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
17.39
Quantity 3,542 -11.4%
Value US$61,608
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
17.96
Quantity 33,000
Value US$592,680
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
13.46
Quantity 11,000
Value US$148,005
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
14.28
Quantity 408 -2.0%
Value US$5,825
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
13.32
Quantity 10,592 -34.2%
Value US$141,096
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
18.50
Quantity 700 -3.4%
Value US$12,950
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
17.50
Quantity 10,300 -33.2%
Value US$180,270
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
18.65
Quantity 11,000
Value US$205,150
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
13.82
Quantity 300 -1.5%
Value US$4,147
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
13.41
Quantity 10,700 -34.5%
Value US$143,436
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
12.68
Quantity 11,000
Value US$139,480
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
13.98
Quantity 11,000
Value US$153,780
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
14.26
Quantity 2,815 -12.3%
Value US$40,143
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
13.67
Quantity 8,185 -26.4%
Value US$111,879
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
12.99
Quantity 11,000 -35.5%
Value US$142,925
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
13.12
Quantity 11,000
Value US$144,320
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
13.12
Quantity 11,000
Value US$144,320
4.0
GWENDOLYN BINDER Officer Officer
Transaction date
Proposed sale
Price
12.30
Quantity 22,000
Value US$270,600
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Planned sale
Price
11.81
Quantity 22,000 -52.4%
Value US$259,833
4.0
Nichtberger Steven President & CEO Executive Director
Transaction date
Purchase
Price
1.25
Quantity 8,127 +0.8%
Value US$10,152
4.0
Simon Mark Non-Executive Director
Transaction date
Purchase
Price
0.98
Quantity 7,000 +inf%
Value US$6,835
4.0
Simon Mark Non-Executive Director
Transaction date
Purchase
Price
0.98
Quantity 118,000 +650.4%
Value US$115,286
4.0
Bollard Catherine Non-Executive Director
Transaction date
Purchase
Price
0.99
Quantity 1,000 +inf%
Value US$994
4.0
Binder Gwendolyn See Remarks Officer
Transaction date
Purchase
Price
0.99
Quantity 20,000 +inf%
Value US$19,894
3.4
Marda Anup Chief Financial Officer Officer
Transaction date
Purchase
Price
0.99
Quantity 50,000 +inf%
Value US$49,620
4.0
Nichtberger Steven President & CEO Executive Director
Transaction date
Purchase
Price
0.99
Quantity 141,873 +17.0%
Value US$141,008
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
13.00
Quantity 36,544 -9.9%
Value US$475,072
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
13.00
Quantity 258,456 -13.0%
Value US$3,359,928
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
13.00
Quantity 10,530 -2.8%
Value US$136,890
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
13.00
Quantity 74,470 -2.8%
Value US$968,110
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
13.00
Quantity 37,411 -9.0%
Value US$486,343
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
13.00
Quantity 264,589 -9.0%
Value US$3,439,657
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
14.75
Quantity 36,916 -8.1%
Value US$544,511
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Sale
Price
14.75
Quantity 261,084 -8.1%
Value US$3,850,989
3.5
5AM Ventures V, L.P. Large shareholder
Transaction date
Purchase
Price
11.00
Quantity 454,545 +inf%
Value US$4,999,995
2.8
Flynn James E Large shareholder
Transaction date
Purchase
Price
11.00
Quantity 700,000 +inf%
Value US$7,700,000
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-01-21 2026-01-21 B Purchase
4.0
Simon Mark
Non-Executive Director
31,698 +34.7%
31.09
US$463,525 		31,698 +34.7% 31.09 US$463,525
2026-01-21 2026-01-21 B Purchase
3.3
Chang David J.

Chief Medical Officer

Officer
61,573 +0.6%
333.54
US$3,373,800 		61,573 +0.6% 333.54 US$3,373,800
2026-01-21 2026-01-21 B Purchase
4.0
Binder Gwendolyn

President, Science & Tech.

Officer
36,097 -42.5%
315.77
US$963,707 		36,097 -42.5% 315.77 US$963,707
2026-01-21 2026-01-21 B Purchase
3.3
Gerard Michael

General Counsel

Officer
6,600 +inf%
2.27
US$14,979 		6,600 +inf% 2.27 US$14,979
2026-01-21 2026-01-21 B Purchase
3.3
Gavel Steve

Chief Commercial Officer

Officer
22,170 +inf%
2.27
US$50,215 		22,170 +inf% 2.27 US$50,215
2026-01-21 2026-01-21 B Purchase
3.7
Tomasello Shawn
Non-Executive Director
22,725 +inf%
2.21
US$50,322 		22,725 +inf% 2.21 US$50,322
2026-01-21 2026-01-21 B Purchase
4.0
Nichtberger Steven

President & CEO

Executive Director
45,000 +4.6%
2.24
US$100,778 		45,000 +4.6% 2.24 US$100,778
2026-01-21 2026-01-21 B Purchase
4.0
Bollard Catherine
Non-Executive Director
4,405 +440.5%
2.27
US$9,982 		4,405 +440.5% 2.27 US$9,982
2024-01-19 2024-01-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
700 -3.4%
20.33
US$14,229 		700 -3.4% 20.33 US$14,229
2024-01-19 2024-01-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
10,300 -33.2%
19.54
US$201,210 		10,300 -33.2% 19.54 US$201,210
2023-12-19 2023-12-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
3,132 -13.5%
22.22
US$69,593 		3,132 -13.5% 22.22 US$69,593
2023-12-19 2023-12-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
7,868 -25.4%
21.76
US$171,196 		7,868 -25.4% 21.76 US$171,196
2023-11-21 2023-11-20 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
7,458 -27.2%
18.02
US$134,405 		7,458 -27.2% 18.02 US$134,405
2023-11-21 2023-11-20 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
3,542 -11.4%
17.39
US$61,608 		3,542 -11.4% 17.39 US$61,608
2023-11-20 2023-11-20 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
33,000
17.96
US$592,680 		33,000 17.96 US$592,680
2023-10-19 2023-10-19 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
11,000
13.46
US$148,005 		11,000 13.46 US$148,005
2023-10-19 2023-10-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
408 -2.0%
14.28
US$5,825 		408 -2.0% 14.28 US$5,825
2023-10-19 2023-10-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
10,592 -34.2%
13.32
US$141,096 		10,592 -34.2% 13.32 US$141,096
2023-09-20 2023-09-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
700 -3.4%
18.50
US$12,950 		700 -3.4% 18.50 US$12,950
2023-09-20 2023-09-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
10,300 -33.2%
17.50
US$180,270 		10,300 -33.2% 17.50 US$180,270
2023-09-19 2023-09-19 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
11,000
18.65
US$205,150 		11,000 18.65 US$205,150
2023-08-22 2023-08-21 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
300 -1.5%
13.82
US$4,147 		300 -1.5% 13.82 US$4,147
2023-08-22 2023-08-21 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
10,700 -34.5%
13.41
US$143,436 		10,700 -34.5% 13.41 US$143,436
2023-08-21 2023-08-21 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
11,000
12.68
US$139,480 		11,000 12.68 US$139,480
2023-07-19 2023-07-19 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
11,000
13.98
US$153,780 		11,000 13.98 US$153,780
2023-07-19 2023-07-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
2,815 -12.3%
14.26
US$40,143 		2,815 -12.3% 14.26 US$40,143
2023-07-19 2023-07-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
8,185 -26.4%
13.67
US$111,879 		8,185 -26.4% 13.67 US$111,879
2023-06-21 2023-06-20 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
11,000 -35.5%
12.99
US$142,925 		11,000 -35.5% 12.99 US$142,925
2023-06-20 2023-06-20 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
11,000
13.12
US$144,320 		11,000 13.12 US$144,320
2023-06-20 2023-06-20 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
11,000
13.12
US$144,320 		11,000 13.12 US$144,320
2023-05-19 2023-05-19 PrS Proposed sale
4.0
GWENDOLYN BINDER

Officer

Officer
22,000
12.30
US$270,600 		22,000 12.30 US$270,600
2023-05-19 2023-05-19 PlS Planned sale
4.0
Binder Gwendolyn

See Remarks

Officer
22,000 -52.4%
11.81
US$259,833 		22,000 -52.4% 11.81 US$259,833
2022-10-19 2022-10-19 B Purchase
4.0
Nichtberger Steven

President & CEO

Executive Director
8,127 +0.8%
1.25
US$10,152 		8,127 +0.8% 1.25 US$10,152
2022-10-18 2022-10-18 B Purchase
4.0
Simon Mark
Non-Executive Director
7,000 +inf%
0.98
US$6,835 		7,000 +inf% 0.98 US$6,835
2022-10-18 2022-10-18 B Purchase
4.0
Simon Mark
Non-Executive Director
118,000 +650.4%
0.98
US$115,286 		118,000 +650.4% 0.98 US$115,286
2022-10-18 2022-10-18 B Purchase
4.0
Bollard Catherine
Non-Executive Director
1,000 +inf%
0.99
US$994 		1,000 +inf% 0.99 US$994
2022-10-18 2022-10-18 B Purchase
4.0
Binder Gwendolyn

See Remarks

Officer
20,000 +inf%
0.99
US$19,894 		20,000 +inf% 0.99 US$19,894
2022-10-18 2022-10-18 B Purchase
3.4
Marda Anup

Chief Financial Officer

Officer
50,000 +inf%
0.99
US$49,620 		50,000 +inf% 0.99 US$49,620
2022-10-18 2022-10-18 B Purchase
4.0
Nichtberger Steven

President & CEO

Executive Director
141,873 +17.0%
0.99
US$141,008 		141,873 +17.0% 0.99 US$141,008
2021-11-03 2021-11-01 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
36,544 -9.9%
13.00
US$475,072 		36,544 -9.9% 13.00 US$475,072
2021-11-03 2021-11-01 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
258,456 -13.0%
13.00
US$3,359,928 		258,456 -13.0% 13.00 US$3,359,928
2021-01-12 2021-01-12 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
10,530 -2.8%
13.00
US$136,890 		10,530 -2.8% 13.00 US$136,890
2021-01-12 2021-01-12 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
74,470 -2.8%
13.00
US$968,110 		74,470 -2.8% 13.00 US$968,110
2021-01-12 2021-01-08 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
37,411 -9.0%
13.00
US$486,343 		37,411 -9.0% 13.00 US$486,343
2021-01-12 2021-01-08 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
264,589 -9.0%
13.00
US$3,439,657 		264,589 -9.0% 13.00 US$3,439,657
2020-12-14 2020-12-10 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
36,916 -8.1%
14.75
US$544,511 		36,916 -8.1% 14.75 US$544,511
2020-12-14 2020-12-10 S Sale
3.5
5AM Ventures V, L.P.
Large shareholder
261,084 -8.1%
14.75
US$3,850,989 		261,084 -8.1% 14.75 US$3,850,989
2019-10-31 2019-10-29 B Purchase
3.5
5AM Ventures V, L.P.
Large shareholder
454,545 +inf%
11.00
US$4,999,995 		454,545 +inf% 11.00 US$4,999,995
2019-10-30 2019-10-29 B Purchase
2.8
Flynn James E
Large shareholder
700,000 +inf%
11.00
US$7,700,000 		700,000 +inf% 11.00 US$7,700,000
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