|
2020-03-19 |
2020-03-17 |
B
Purchase
|
President and CEO
Executive Director
|
15,202
-36.0%
131.57
US$3,657,421
|
15,202
-36.0%
|
131.57
|
US$3,657,421
|
|
|
2019-09-11 |
2019-09-10 |
B
Purchase
|
President and CEO
Executive Director
|
22,493
+10.4%
337.17
US$4,126,439
|
22,493
+10.4%
|
337.17
|
US$4,126,439
|
|
|
2019-08-30 |
2019-08-29 |
PP
Planned purchase
|
Ward Shane
Sr. VP and General Counsel
Officer
|
52,212
+46.3%
187.80
US$2,544,649
|
52,212
+46.3%
|
187.80
|
US$2,544,649
|
|
|
2019-08-23 |
2019-08-21 |
PP
Planned purchase
|
Fair Richard A.
President and CEO
Executive Director
|
20,000
+304.8%
0.99
US$19,780
|
20,000
+304.8%
|
0.99
|
US$19,780
|
|
|
2018-11-13 |
2018-11-09 |
B
Purchase
|
Stonehouse Jon P
Non-Executive Director
|
10,000
+inf%
4.56
US$45,600
|
10,000
+inf%
|
4.56
|
US$45,600
|
|
|
2018-09-05 |
2018-09-04 |
PlS
Planned sale
|
Spencer David M.
Chief Technology Officer
Officer
|
10,000
-10.0%
7.04
US$70,413
|
10,000
-10.0%
|
7.04
|
US$70,413
|
|
|
2018-07-20 |
2018-07-18 |
PlS
Planned sale
|
Spencer David M.
Chief Technology Officer
Officer
|
40,000
-28.6%
7.63
US$305,132
|
40,000
-28.6%
|
7.63
|
US$305,132
|
|
|
2018-05-29 |
2018-05-25 |
PlS
Planned sale
|
Musso Alan A
CFO and Treasurer
Officer
|
6,206
-18.9%
7.97
US$49,466
|
6,206
-18.9%
|
7.97
|
US$49,466
|
|
|
2018-01-19 |
2018-01-19 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
4,136
-6.6%
7.91
US$32,715
|
4,136
-6.6%
|
7.91
|
US$32,715
|
|
|
2018-01-19 |
2018-01-19 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
265,708
-6.6%
7.91
US$2,101,671
|
265,708
-6.6%
|
7.91
|
US$2,101,671
|
|
|
2018-01-19 |
2018-01-19 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
25,517
-6.6%
7.91
US$201,832
|
25,517
-6.6%
|
7.91
|
US$201,832
|
|
|
2018-01-19 |
2018-01-18 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
4,548
-6.8%
8.12
US$36,910
|
4,548
-6.8%
|
8.12
|
US$36,910
|
|
|
2018-01-19 |
2018-01-18 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
292,168
-6.8%
8.12
US$2,371,148
|
292,168
-6.8%
|
8.12
|
US$2,371,148
|
|
|
2018-01-19 |
2018-01-18 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
28,058
-6.8%
8.12
US$227,710
|
28,058
-6.8%
|
8.12
|
US$227,710
|
|
|
2018-01-19 |
2018-01-17 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
3,649
-5.2%
8.63
US$31,476
|
3,649
-5.2%
|
8.63
|
US$31,476
|
|
|
2018-01-19 |
2018-01-17 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
234,437
-5.2%
8.63
US$2,022,230
|
234,437
-5.2%
|
8.63
|
US$2,022,230
|
|
|
2018-01-19 |
2018-01-17 |
S
Sale
|
BAKER BROS. ADVISORS LP
Large shareholder
|
22,514
-5.2%
8.63
US$194,204
|
22,514
-5.2%
|
8.63
|
US$194,204
|
|
|
2018-01-11 |
2018-01-09 |
PlS
Planned sale
|
Smith Alan K.
EVP, Technical Operations
Officer
|
487
-18.9%
9.40
US$4,578
|
487
-18.9%
|
9.40
|
US$4,578
|
|
|
2017-12-13 |
2017-12-11 |
PlS
Planned sale
|
Musso Alan A
CFO and Treasurer
|
17,117
-35.1%
9.33
US$159,667
|
17,117
-35.1%
|
9.33
|
US$159,667
|
|
|
2017-07-26 |
2017-07-24 |
PlS
Planned sale
|
Smith Alan K.
EVP, Technical Operations
Officer
|
437
-21.5%
11.85
US$5,178
|
437
-21.5%
|
11.85
|
US$5,178
|
|
|
2017-07-17 |
2017-07-13 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
13,823
-96.6%
12.26
US$169,470
|
13,823
-96.6%
|
12.26
|
US$169,470
|
|
|
2017-07-12 |
2017-07-10 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
10,000
-6.7%
11.54
US$115,400
|
10,000
-6.7%
|
11.54
|
US$115,400
|
|
|
2017-05-26 |
2017-05-25 |
PlS
Planned sale
|
CFO and Treasurer
Officer
|
6,311
-10.3%
12.24
US$77,254
|
6,311
-10.3%
|
12.24
|
US$77,254
|
|
|
2017-03-28 |
2017-03-24 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
151,177
+3.5%
12.00
US$1,814,124
|
151,177
+3.5%
|
12.00
|
US$1,814,124
|
|
|
2017-03-28 |
2017-03-24 |
B
Purchase
|
BAKER BROS. ADVISORS LP
Large shareholder
|
15,489
+3.7%
12.00
US$185,868
|
15,489
+3.7%
|
12.00
|
US$185,868
|
|
|
2017-02-09 |
2017-02-07 |
PlS
Planned sale
|
Slawin Kevin M.
|
30,000
-9.2%
12.54
US$376,215
|
30,000
-9.2%
|
12.54
|
US$376,215
|
|
|
2016-12-19 |
2016-12-15 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
30,000
-8.5%
15.45
US$463,539
|
30,000
-8.5%
|
15.45
|
US$463,539
|
|
|
2016-12-05 |
2016-12-05 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
5,000
-3.3%
20.00
US$100,000
|
5,000
-3.3%
|
20.00
|
US$100,000
|
|
|
2016-12-05 |
2016-12-01 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
2,033
-1.3%
18.04
US$36,682
|
2,033
-1.3%
|
18.04
|
US$36,682
|
|
|
2016-12-05 |
2016-12-01 |
PlS
Planned sale
|
Moseley Annemarie
COO/EVP Clinical Development
Officer
|
10,542
-96.0%
18.04
US$190,195
|
10,542
-96.0%
|
18.04
|
US$190,195
|
|
|
2016-12-05 |
2016-12-01 |
PlS
Planned sale
|
Moseley Annemarie
COO/EVP Clinical Development
Officer
|
14,458
-56.8%
17.17
US$248,310
|
14,458
-56.8%
|
17.17
|
US$248,310
|
|
|
2016-12-05 |
2016-12-01 |
PlS
Planned sale
|
Chief Scientific Officer
Officer
|
2,967
-1.9%
17.17
US$50,942
|
2,967
-1.9%
|
17.17
|
US$50,942
|
|
|
2016-11-29 |
2016-11-28 |
PlS
Planned sale
|
Musso Alan A
CFO and Treasurer
Officer
|
600
-1.0%
19.85
US$11,907
|
600
-1.0%
|
19.85
|
US$11,907
|
|
|
2016-11-29 |
2016-11-28 |
PlS
Planned sale
|
Musso Alan A
CFO and Treasurer
Officer
|
22,427
-26.8%
19.23
US$431,253
|
22,427
-26.8%
|
19.23
|
US$431,253
|
|
|
2016-11-29 |
2016-11-25 |
PlS
Planned sale
|
CFO and Treasurer
Officer
|
6,273
-7.0%
20.48
US$128,480
|
6,273
-7.0%
|
20.48
|
US$128,480
|
|
|
2016-09-23 |
2016-09-23 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
11,958
-3.3%
20.11
US$240,530
|
11,958
-3.3%
|
20.11
|
US$240,530
|
|
|
2016-09-23 |
2016-09-23 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
11,258
-11.8%
20.12
US$226,549
|
11,258
-11.8%
|
20.12
|
US$226,549
|
|
|
2016-09-23 |
2016-09-23 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
11,700
-97.1%
20.10
US$235,198
|
11,700
-97.1%
|
20.10
|
US$235,198
|
|
|
2016-09-23 |
2016-09-23 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
6,200
-3.8%
20.19
US$125,172
|
6,200
-3.8%
|
20.19
|
US$125,172
|
|
|
2016-09-23 |
2016-09-22 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
10,000
-5.8%
19.68
US$196,832
|
10,000
-5.8%
|
19.68
|
US$196,832
|
|
|
2016-09-23 |
2016-09-21 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
100
-0.0%
20.04
US$2,004
|
100
-0.0%
|
20.04
|
US$2,004
|
|
|
2016-09-23 |
2016-09-21 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
100
-22.5%
20.04
US$2,004
|
100
-22.5%
|
20.04
|
US$2,004
|
|
|
2016-09-23 |
2016-09-21 |
PlS
Planned sale
|
Chief Technology Officer
Executive Director
|
100
-0.1%
20.04
US$2,004
|
100
-0.1%
|
20.04
|
US$2,004
|
|
|
2016-09-23 |
2016-09-21 |
PlS
Planned sale
|
Chief Scientific Officer
Officer
|
300
-0.2%
20.04
US$6,012
|
300
-0.2%
|
20.04
|
US$6,012
|
|
|
2016-09-20 |
2016-09-20 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
100
-0.1%
20.00
US$2,000
|
100
-0.1%
|
20.00
|
US$2,000
|
|
|
2016-09-20 |
2016-09-20 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
200
-36.8%
20.00
US$4,000
|
200
-36.8%
|
20.00
|
US$4,000
|
|
|
2016-09-20 |
2016-09-20 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
100
-0.0%
20.00
US$2,000
|
100
-0.0%
|
20.00
|
US$2,000
|
|
|
2016-09-20 |
2016-09-20 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
300
-0.3%
20.00
US$6,000
|
300
-0.3%
|
20.00
|
US$6,000
|
|
|
2016-09-20 |
2016-09-19 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
700
-0.4%
20.02
US$14,013
|
700
-0.4%
|
20.02
|
US$14,013
|
|
|
2016-09-20 |
2016-09-19 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
1,300
-79.1%
20.01
US$26,018
|
1,300
-79.1%
|
20.01
|
US$26,018
|
|
|
2016-09-20 |
2016-09-19 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
1,206
-0.3%
20.01
US$24,129
|
1,206
-0.3%
|
20.01
|
US$24,129
|
|
|
2016-09-20 |
2016-09-19 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
1,400
-1.4%
20.02
US$28,024
|
1,400
-1.4%
|
20.02
|
US$28,024
|
|
|
2016-09-20 |
2016-09-16 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
700
-67.0%
20.00
US$14,000
|
700
-67.0%
|
20.00
|
US$14,000
|
|
|
2016-09-20 |
2016-09-16 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
636
-0.2%
20.00
US$12,720
|
636
-0.2%
|
20.00
|
US$12,720
|
|
|
2016-09-20 |
2016-09-16 |
PlS
Planned sale
|
Chief Scientific Officer
Officer
|
1,700
-1.0%
20.01
US$34,015
|
1,700
-1.0%
|
20.01
|
US$34,015
|
|
|
2016-09-20 |
2016-09-16 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
942
-1.0%
20.00
US$18,840
|
942
-1.0%
|
20.00
|
US$18,840
|
|
|
2016-08-17 |
2016-08-15 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
2,000
-0.5%
20.01
US$40,020
|
2,000
-0.5%
|
20.01
|
US$40,020
|
|
|
2016-08-17 |
2016-08-15 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
29,000
-7.3%
19.27
US$558,911
|
29,000
-7.3%
|
19.27
|
US$558,911
|
|
|
2016-08-17 |
2016-08-15 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
1,873
-1.9%
20.01
US$37,470
|
1,873
-1.9%
|
20.01
|
US$37,470
|
|
|
2016-08-17 |
2016-08-15 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
1,000
-74.4%
20.00
US$20,000
|
1,000
-74.4%
|
20.00
|
US$20,000
|
|
|
2016-08-17 |
2016-08-15 |
PlS
Planned sale
|
Chief Technology Officer
Executive Director
|
34,127
-25.4%
19.27
US$657,542
|
34,127
-25.4%
|
19.27
|
US$657,542
|
|
|
2016-08-17 |
2016-08-15 |
PlS
Planned sale
|
Chief Scientific Officer
Officer
|
1,000
-0.6%
20.00
US$20,000
|
1,000
-0.6%
|
20.00
|
US$20,000
|
|
|
2016-07-29 |
2016-07-27 |
PlS
Planned sale
|
Chief Technology Officer
Executive Director
|
15,000
-3.6%
15.00
US$225,000
|
15,000
-3.6%
|
15.00
|
US$225,000
|
|
|
2016-07-29 |
2016-07-27 |
PlS
Planned sale
|
Spencer David M.
Chief Scientific Officer
Officer
|
10,000
-5.4%
15.00
US$150,000
|
10,000
-5.4%
|
15.00
|
US$150,000
|
|
|
2016-07-19 |
2016-07-18 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
2,719
-2.0%
13.99
US$38,044
|
2,719
-2.0%
|
13.99
|
US$38,044
|
|
|
2016-07-19 |
2016-07-15 |
PlS
Planned sale
|
Chief Technology Officer
Executive Director
|
22,281
-14.0%
13.72
US$305,677
|
22,281
-14.0%
|
13.72
|
US$305,677
|
|
|
2016-06-06 |
2016-06-02 |
PlS
Planned sale
|
Moseley Annemarie
COO/EVP Clinical Development
Officer
|
6,765
-96.4%
13.00
US$87,945
|
6,765
-96.4%
|
13.00
|
US$87,945
|
|
|
2016-06-06 |
2016-06-02 |
PlS
Planned sale
|
Moseley Annemarie
COO/EVP Clinical Development
Officer
|
18,235
-98.6%
13.00
US$237,055
|
18,235
-98.6%
|
13.00
|
US$237,055
|
|
|
2016-06-06 |
2016-06-02 |
PlS
Planned sale
|
Moseley Ken
Sr. VP and General Counsel
Officer
|
15,000
-98.7%
13.00
US$195,000
|
15,000
-98.7%
|
13.00
|
US$195,000
|
|
|
2016-04-26 |
2016-04-22 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
200
-0.0%
11.89
US$2,377
|
200
-0.0%
|
11.89
|
US$2,377
|
|
|
2016-04-26 |
2016-04-22 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
29,800
-6.7%
11.42
US$340,411
|
29,800
-6.7%
|
11.42
|
US$340,411
|
|
|
2016-04-26 |
2016-04-22 |
PlS
Planned sale
|
Chief Technology Officer
Executive Director
|
25,000
-13.6%
11.43
US$285,710
|
25,000
-13.6%
|
11.43
|
US$285,710
|
|
|
2016-01-06 |
2016-01-04 |
PlS
Planned sale
|
Moseley Annemarie
COO/EVP Clinical Development
Officer
|
2,300
-90.2%
19.96
US$45,903
|
2,300
-90.2%
|
19.96
|
US$45,903
|
|
|
2016-01-06 |
2016-01-04 |
PlS
Planned sale
|
Moseley Annemarie
COO/EVP Clinical Development
Officer
|
32,700
-92.8%
19.01
US$621,591
|
32,700
-92.8%
|
19.01
|
US$621,591
|
|
|
2015-11-18 |
2015-11-16 |
PlS
Planned sale
|
Slawin Kevin M.
Chief Technology Officer
Executive Director
|
4,000
-1.0%
20.65
US$82,585
|
4,000
-1.0%
|
20.65
|
US$82,585
|
|