United States Biotechnology & Medical Research

ArQule Inc (ARQL)

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Track

Ticker: ARQL Exchange: NMS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
No insider activity signals detected

Insider trades have not triggered unusual activity signals for this company.

Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
0.6
Nussbaum Ran
Transaction date
Purchase
Price
243.34
Quantity 77,544 -17.4%
Value US$4,943,461
0.6
Nussbaum Ran
Transaction date
Purchase
Price
305.99
Quantity 56,858 -13.9%
Value US$373,669
0.6
Nussbaum Ran
Transaction date
Purchase
Price
132.91
Quantity 51,514 +7.4%
Value US$1,300,231
0.6
Nussbaum Ran
Transaction date
Purchase
Price
9.75
Quantity 133,548 +4.0%
Value US$1,302,093
Nussbaum Ran Non-Executive Director
Transaction date
Purchase
Price
5.50
Quantity 43,657 +2.8%
Value US$240,114
Nussbaum Ran Non-Executive Director
Transaction date
Purchase
Price
5.50
Quantity 89,676 +2.8%
Value US$493,218
Nussbaum Ran Non-Executive Director
Transaction date
Purchase
Price
5.50
Quantity 48,485 +2.8%
Value US$266,668
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
5.00
Quantity 175,813 -18.6%
Value US$879,083
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
5.00
Quantity 312,266 -8.9%
Value US$1,561,361
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
5.00
Quantity 547,860 -10.5%
Value US$2,739,355
Nussbaum Ran Non-Executive Director
Transaction date
Purchase
Price
3.29
Quantity 8,611 +inf%
Value US$28,330
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
3.39
Quantity 15,000 +3.7%
Value US$50,848
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
2.96
Quantity 8,446 +11.4%
Value US$24,987
LINDSAY RONALD M Non-Executive Director
Transaction date
Purchase
Price
2.69
Quantity 6,900 +15.7%
Value US$18,589
LINDSAY RONALD M Non-Executive Director
Transaction date
Purchase
Price
2.67
Quantity 23,900 +119.5%
Value US$63,837
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
2.64
Quantity 1,300 +0.3%
Value US$3,427
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
3.10
Quantity 217,256 -18.7%
Value US$673,494
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
3.10
Quantity 808,449 -18.8%
Value US$2,506,192
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
3.10
Quantity 1,204,668 -18.7%
Value US$3,734,471
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
2.90
Quantity 214,336 -15.5%
Value US$621,574
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
2.90
Quantity 817,611 -16.0%
Value US$2,371,072
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
2.90
Quantity 1,269,634 -16.5%
Value US$3,681,939
Pucci Paolo Chief Executive Officer
Transaction date
Purchase
Price
1.15
Quantity 1,101 +0.3%
Value US$1,261
Pucci Paolo Chief Executive Officer
Transaction date
Purchase
Price
1.15
Quantity 16,397 +4.2%
Value US$18,840
Pucci Paolo Chief Executive Officer
Transaction date
Purchase
Price
1.14
Quantity 19,156 +5.2%
Value US$21,844
Pucci Paolo Chief Executive Officer
Transaction date
Purchase
Price
1.05
Quantity 300 +0.1%
Value US$315
Pucci Paolo Chief Executive Officer
Transaction date
Purchase
Price
1.05
Quantity 2,970 +0.8%
Value US$3,115
Pucci Paolo Chief Executive Officer
Transaction date
Purchase
Price
1.05
Quantity 701 +0.2%
Value US$736
Pucci Paolo Chief Executive Officer
Transaction date
Purchase
Price
1.05
Quantity 8,791 +2.5%
Value US$9,212
LOBERG MICHAEL D Non-Executive Director
Transaction date
Purchase
Price
2.16
Quantity 3,719 +2.9%
Value US$8,030
LOBERG MICHAEL D Non-Executive Director
Transaction date
Purchase
Price
2.14
Quantity 1,231 +1.0%
Value US$2,633
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
2.16
Quantity 1,283 +0.5%
Value US$2,771
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
2.15
Quantity 2,300 +3.2%
Value US$4,947
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
2.10
Quantity 1,108 +0.4%
Value US$2,324
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
2.10
Quantity 6,600 +2.7%
Value US$13,844
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
2.10
Quantity 1,009 +0.4%
Value US$2,119
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
2.32
Quantity 10,625 +17.5%
Value US$24,647
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
1.26
Quantity 5,000 +2.1%
Value US$6,298
Messenger William G Non-Executive Director
Transaction date
Purchase
Price
1.21
Quantity 8,500 +566.7%
Value US$10,284
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
1.20
Quantity 20,830 +52.1%
Value US$24,952
Kelley Susan L. Non-Executive Director
Transaction date
Purchase
Price
1.20
Quantity 50,000 +inf%
Value US$60,160
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
1.31
Quantity 5,000 +2.1%
Value US$6,525
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
1.40
Quantity 5,000 +2.2%
Value US$7,010
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
1.42
Quantity 5,000 +2.2%
Value US$7,124
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
2.12
Quantity 4,715 +13.4%
Value US$10,009
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
2.10
Quantity 10,000 +4.6%
Value US$20,990
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
6.47
Quantity 4,000 +12.8%
Value US$25,871
Pucci Paolo Chief Executive Officer Officer
Transaction date
Purchase
Price
6.24
Quantity 4,754 +2.2%
Value US$29,684
Lawrence Peter S President & COO Officer
Transaction date
Purchase
Price
6.25
Quantity 1,000 +1.4%
Value US$6,254
SCHWARTZ BRIAN Chief Medical Officer Officer
Transaction date
Purchase
Price
6.26
Quantity 4,700 +20.0%
Value US$29,412
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
5.53
Quantity 4,400 +16.4%
Value US$24,321
SCHWARTZ BRIAN Chief Medical Officer Officer
Transaction date
Purchase
Price
4.41
Quantity 4,000 +19.4%
Value US$17,621
Pucci Paolo Chief Executive Officer Executive Director
Transaction date
Purchase
Price
4.45
Quantity 6,600 +3.2%
Value US$29,376
LOBERG MICHAEL D Non-Executive Director
Transaction date
Purchase
Price
6.40
Quantity 27,676 +68.0%
Value US$177,063
LOBERG MICHAEL D Non-Executive Director
Transaction date
Purchase
Price
6.32
Quantity 1,398 +3.6%
Value US$8,838
BVF PARTNERS L P/IL Direct Beneficial Owner Large shareholder
Transaction date
Sale
Price
6.13
Quantity 354,000 -7.8%
Value US$2,170,303
BVF PARTNERS L P/IL Direct Beneficial Owner Large shareholder
Transaction date
Sale
Price
6.13
Quantity 102,000 -2.2%
Value US$625,342
BVF PARTNERS L P/IL Direct Beneficial Owner Large shareholder
Transaction date
Sale
Price
6.13
Quantity 147,000 -3.1%
Value US$901,228
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
5.81
Quantity 653,000 -12.0%
Value US$3,794,779
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
5.81
Quantity 188,000 -3.3%
Value US$1,092,524
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
5.81
Quantity 272,000 -4.6%
Value US$1,580,674
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
6.24
Quantity 1,548,000 -20.7%
Value US$9,660,758
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
6.24
Quantity 447,000 -5.6%
Value US$2,789,638
BVF PARTNERS L P/IL Large shareholder
Transaction date
Sale
Price
6.24
Quantity 645,000 -7.5%
Value US$4,025,316
ZENNER PATRICK J Non-Executive Director
Transaction date
Purchase
Price
3.58
Quantity 6,900 +34.5%
Value US$24,734
Pucci Paolo Chief Executive Officer Executive Director
Transaction date
Purchase
Price
3.48
Quantity 5,000 +2.4%
Value US$17,420
BVF PARTNERS L P/IL Direct Beneficial Owner Large shareholder
Transaction date
Sale
Price
5.25
Quantity 2,100,000 -19.7%
Value US$11,025,000
BVF PARTNERS L P/IL Direct Beneficial Owner Large shareholder
Transaction date
Sale
Price
5.25
Quantity 660,000 -5.8%
Value US$3,465,000
BVF PARTNERS L P/IL Direct Beneficial Owner Large shareholder
Transaction date
Sale
Price
5.25
Quantity 920,000 -7.5%
Value US$4,830,000
BARABE TIMOTHY C Non-Executive Director
Transaction date
Purchase
Price
5.26
Quantity 784 +3.1%
Value US$4,124
LOBERG MICHAEL D Non-Executive Director
Transaction date
Purchase
Price
5.26
Quantity 356 +0.6%
Value US$1,873
LOBERG MICHAEL D Non-Executive Director
Transaction date
Purchase
Price
5.65
Quantity 88 +0.1%
Value US$497
BARABE TIMOTHY C Non-Executive Director
Transaction date
Purchase
Price
5.73
Quantity 104 +0.4%
Value US$596
BARABE TIMOTHY C Non-Executive Director
Transaction date
Purchase
Price
5.82
Quantity 206 +0.8%
Value US$1,199
LOBERG MICHAEL D Non-Executive Director
Transaction date
Purchase
Price
5.82
Quantity 171 +0.3%
Value US$995
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2019-07-01 2019-06-27 B Purchase
0.6
Nussbaum Ran
77,544 -17.4%
243.34
US$4,943,461 		77,544 -17.4% 243.34 US$4,943,461
2019-07-01 2019-06-27 B Purchase
0.6
Nussbaum Ran
56,858 -13.9%
305.99
US$373,669 		56,858 -13.9% 305.99 US$373,669
2019-07-01 2019-06-27 B Purchase
0.6
Nussbaum Ran
51,514 +7.4%
132.91
US$1,300,231 		51,514 +7.4% 132.91 US$1,300,231
2019-07-01 2019-06-27 B Purchase
0.6
Nussbaum Ran
133,548 +4.0%
9.75
US$1,302,093 		133,548 +4.0% 9.75 US$1,302,093
2018-10-22 2018-07-13 B Purchase Nussbaum Ran Non-Executive Director
43,657 +2.8%
5.50
US$240,114 		43,657 +2.8% 5.50 US$240,114
2018-10-22 2018-07-13 B Purchase Nussbaum Ran Non-Executive Director
89,676 +2.8%
5.50
US$493,218 		89,676 +2.8% 5.50 US$493,218
2018-10-22 2018-07-13 B Purchase Nussbaum Ran Non-Executive Director
48,485 +2.8%
5.50
US$266,668 		48,485 +2.8% 5.50 US$266,668
2018-06-01 2018-05-30 S Sale BVF PARTNERS L P/IL Large shareholder
175,813 -18.6%
5.00
US$879,083 		175,813 -18.6% 5.00 US$879,083
2018-06-01 2018-05-30 S Sale BVF PARTNERS L P/IL Large shareholder
312,266 -8.9%
5.00
US$1,561,361 		312,266 -8.9% 5.00 US$1,561,361
2018-06-01 2018-05-30 S Sale BVF PARTNERS L P/IL Large shareholder
547,860 -10.5%
5.00
US$2,739,355 		547,860 -10.5% 5.00 US$2,739,355
2018-05-18 2018-05-18 B Purchase Nussbaum Ran Non-Executive Director
8,611 +inf%
3.29
US$28,330 		8,611 +inf% 3.29 US$28,330
2018-05-18 2018-05-18 B Purchase Pucci Paolo

Chief Executive Officer

Officer
15,000 +3.7%
3.39
US$50,848 		15,000 +3.7% 3.39 US$50,848
2018-05-15 2018-05-14 B Purchase ZENNER PATRICK J Non-Executive Director
8,446 +11.4%
2.96
US$24,987 		8,446 +11.4% 2.96 US$24,987
2018-05-15 2018-05-11 B Purchase LINDSAY RONALD M Non-Executive Director
6,900 +15.7%
2.69
US$18,589 		6,900 +15.7% 2.69 US$18,589
2018-05-11 2018-05-10 B Purchase LINDSAY RONALD M Non-Executive Director
23,900 +119.5%
2.67
US$63,837 		23,900 +119.5% 2.67 US$63,837
2018-05-11 2018-05-10 B Purchase Pucci Paolo

Chief Executive Officer

Officer
1,300 +0.3%
2.64
US$3,427 		1,300 +0.3% 2.64 US$3,427
2018-04-20 2018-04-18 S Sale BVF PARTNERS L P/IL Large shareholder
217,256 -18.7%
3.10
US$673,494 		217,256 -18.7% 3.10 US$673,494
2018-04-20 2018-04-18 S Sale BVF PARTNERS L P/IL Large shareholder
808,449 -18.8%
3.10
US$2,506,192 		808,449 -18.8% 3.10 US$2,506,192
2018-04-20 2018-04-18 S Sale BVF PARTNERS L P/IL Large shareholder
1,204,668 -18.7%
3.10
US$3,734,471 		1,204,668 -18.7% 3.10 US$3,734,471
2018-04-06 2018-04-04 S Sale BVF PARTNERS L P/IL Large shareholder
214,336 -15.5%
2.90
US$621,574 		214,336 -15.5% 2.90 US$621,574
2018-04-06 2018-04-04 S Sale BVF PARTNERS L P/IL Large shareholder
817,611 -16.0%
2.90
US$2,371,072 		817,611 -16.0% 2.90 US$2,371,072
2018-04-06 2018-04-04 S Sale BVF PARTNERS L P/IL Large shareholder
1,269,634 -16.5%
2.90
US$3,681,939 		1,269,634 -16.5% 2.90 US$3,681,939
2017-09-08 2017-09-07 B Purchase Pucci Paolo

Chief Executive Officer
1,101 +0.3%
1.15
US$1,261 		1,101 +0.3% 1.15 US$1,261
2017-09-07 2017-09-06 B Purchase Pucci Paolo

Chief Executive Officer
16,397 +4.2%
1.15
US$18,840 		16,397 +4.2% 1.15 US$18,840
2017-09-06 2017-09-05 B Purchase Pucci Paolo

Chief Executive Officer
19,156 +5.2%
1.14
US$21,844 		19,156 +5.2% 1.14 US$21,844
2017-08-31 2017-08-29 B Purchase Pucci Paolo

Chief Executive Officer
300 +0.1%
1.05
US$315 		300 +0.1% 1.05 US$315
2017-08-29 2017-08-28 B Purchase Pucci Paolo

Chief Executive Officer
2,970 +0.8%
1.05
US$3,115 		2,970 +0.8% 1.05 US$3,115
2017-08-28 2017-08-25 B Purchase Pucci Paolo

Chief Executive Officer
701 +0.2%
1.05
US$736 		701 +0.2% 1.05 US$736
2017-08-28 2017-08-24 B Purchase Pucci Paolo

Chief Executive Officer
8,791 +2.5%
1.05
US$9,212 		8,791 +2.5% 1.05 US$9,212
2015-12-18 2015-12-17 B Purchase LOBERG MICHAEL D Non-Executive Director
3,719 +2.9%
2.16
US$8,030 		3,719 +2.9% 2.16 US$8,030
2015-12-17 2015-12-16 B Purchase LOBERG MICHAEL D Non-Executive Director
1,231 +1.0%
2.14
US$2,633 		1,231 +1.0% 2.14 US$2,633
2015-12-16 2015-12-15 B Purchase Pucci Paolo

Chief Executive Officer

Officer
1,283 +0.5%
2.16
US$2,771 		1,283 +0.5% 2.16 US$2,771
2015-12-14 2015-12-11 B Purchase ZENNER PATRICK J Non-Executive Director
2,300 +3.2%
2.15
US$4,947 		2,300 +3.2% 2.15 US$4,947
2015-12-14 2015-12-11 B Purchase Pucci Paolo

Chief Executive Officer

Officer
1,108 +0.4%
2.10
US$2,324 		1,108 +0.4% 2.10 US$2,324
2015-12-11 2015-12-10 B Purchase Pucci Paolo

Chief Executive Officer

Officer
6,600 +2.7%
2.10
US$13,844 		6,600 +2.7% 2.10 US$13,844
2015-12-11 2015-12-09 B Purchase Pucci Paolo

Chief Executive Officer

Officer
1,009 +0.4%
2.10
US$2,119 		1,009 +0.4% 2.10 US$2,119
2015-03-12 2015-03-11 B Purchase ZENNER PATRICK J Non-Executive Director
10,625 +17.5%
2.32
US$24,647 		10,625 +17.5% 2.32 US$24,647
2014-11-20 2014-11-20 B Purchase Pucci Paolo

Chief Executive Officer

Officer
5,000 +2.1%
1.26
US$6,298 		5,000 +2.1% 1.26 US$6,298
2014-11-18 2014-11-14 B Purchase Messenger William G Non-Executive Director
8,500 +566.7%
1.21
US$10,284 		8,500 +566.7% 1.21 US$10,284
2014-11-17 2014-11-14 B Purchase ZENNER PATRICK J Non-Executive Director
20,830 +52.1%
1.20
US$24,952 		20,830 +52.1% 1.20 US$24,952
2014-11-17 2014-11-13 B Purchase Kelley Susan L. Non-Executive Director
50,000 +inf%
1.20
US$60,160 		50,000 +inf% 1.20 US$60,160
2014-09-05 2014-09-04 B Purchase Pucci Paolo

Chief Executive Officer

Officer
5,000 +2.1%
1.31
US$6,525 		5,000 +2.1% 1.31 US$6,525
2014-05-27 2014-05-23 B Purchase Pucci Paolo

Chief Executive Officer

Officer
5,000 +2.2%
1.40
US$7,010 		5,000 +2.2% 1.40 US$7,010
2014-05-21 2014-05-20 B Purchase Pucci Paolo

Chief Executive Officer

Officer
5,000 +2.2%
1.42
US$7,124 		5,000 +2.2% 1.42 US$7,124
2014-03-19 2014-03-17 B Purchase ZENNER PATRICK J Non-Executive Director
4,715 +13.4%
2.12
US$10,009 		4,715 +13.4% 2.12 US$10,009
2014-03-14 2014-03-13 B Purchase Pucci Paolo

Chief Executive Officer

Officer
10,000 +4.6%
2.10
US$20,990 		10,000 +4.6% 2.10 US$20,990
2012-06-14 2012-06-12 B Purchase ZENNER PATRICK J Non-Executive Director
4,000 +12.8%
6.47
US$25,871 		4,000 +12.8% 6.47 US$25,871
2012-06-07 2012-06-06 B Purchase Pucci Paolo

Chief Executive Officer

Officer
4,754 +2.2%
6.24
US$29,684 		4,754 +2.2% 6.24 US$29,684
2012-06-07 2012-06-06 B Purchase Lawrence Peter S

President & COO

Officer
1,000 +1.4%
6.25
US$6,254 		1,000 +1.4% 6.25 US$6,254
2012-06-07 2012-06-06 B Purchase SCHWARTZ BRIAN

Chief Medical Officer

Officer
4,700 +20.0%
6.26
US$29,412 		4,700 +20.0% 6.26 US$29,412
2011-12-05 2011-12-02 B Purchase ZENNER PATRICK J Non-Executive Director
4,400 +16.4%
5.53
US$24,321 		4,400 +16.4% 5.53 US$24,321
2011-09-01 2011-08-31 B Purchase SCHWARTZ BRIAN

Chief Medical Officer

Officer
4,000 +19.4%
4.41
US$17,621 		4,000 +19.4% 4.41 US$17,621
2011-08-24 2011-08-24 B Purchase Pucci Paolo

Chief Executive Officer

Executive Director
6,600 +3.2%
4.45
US$29,376 		6,600 +3.2% 4.45 US$29,376
2011-06-09 2011-06-07 B Purchase LOBERG MICHAEL D Non-Executive Director
27,676 +68.0%
6.40
US$177,063 		27,676 +68.0% 6.40 US$177,063
2011-05-26 2011-05-25 B Purchase LOBERG MICHAEL D Non-Executive Director
1,398 +3.6%
6.32
US$8,838 		1,398 +3.6% 6.32 US$8,838
2010-04-07 2010-04-05 S Sale BVF PARTNERS L P/IL

Direct Beneficial Owner

Large shareholder
354,000 -7.8%
6.13
US$2,170,303 		354,000 -7.8% 6.13 US$2,170,303
2010-04-07 2010-04-05 S Sale BVF PARTNERS L P/IL

Direct Beneficial Owner

Large shareholder
102,000 -2.2%
6.13
US$625,342 		102,000 -2.2% 6.13 US$625,342
2010-04-07 2010-04-05 S Sale BVF PARTNERS L P/IL

Direct Beneficial Owner

Large shareholder
147,000 -3.1%
6.13
US$901,228 		147,000 -3.1% 6.13 US$901,228
2010-04-02 2010-04-01 S Sale BVF PARTNERS L P/IL Large shareholder
653,000 -12.0%
5.81
US$3,794,779 		653,000 -12.0% 5.81 US$3,794,779
2010-04-02 2010-04-01 S Sale BVF PARTNERS L P/IL Large shareholder
188,000 -3.3%
5.81
US$1,092,524 		188,000 -3.3% 5.81 US$1,092,524
2010-04-02 2010-04-01 S Sale BVF PARTNERS L P/IL Large shareholder
272,000 -4.6%
5.81
US$1,580,674 		272,000 -4.6% 5.81 US$1,580,674
2010-04-02 2010-03-31 S Sale BVF PARTNERS L P/IL Large shareholder
1,548,000 -20.7%
6.24
US$9,660,758 		1,548,000 -20.7% 6.24 US$9,660,758
2010-04-02 2010-03-31 S Sale BVF PARTNERS L P/IL Large shareholder
447,000 -5.6%
6.24
US$2,789,638 		447,000 -5.6% 6.24 US$2,789,638
2010-04-02 2010-03-31 S Sale BVF PARTNERS L P/IL Large shareholder
645,000 -7.5%
6.24
US$4,025,316 		645,000 -7.5% 6.24 US$4,025,316
2009-11-30 2009-11-25 B Purchase ZENNER PATRICK J Non-Executive Director
6,900 +34.5%
3.58
US$24,734 		6,900 +34.5% 3.58 US$24,734
2009-11-13 2009-11-12 B Purchase Pucci Paolo

Chief Executive Officer

Executive Director
5,000 +2.4%
3.48
US$17,420 		5,000 +2.4% 3.48 US$17,420
2009-09-21 2009-09-17 S Sale BVF PARTNERS L P/IL

Direct Beneficial Owner

Large shareholder
2,100,000 -19.7%
5.25
US$11,025,000 		2,100,000 -19.7% 5.25 US$11,025,000
2009-09-21 2009-09-17 S Sale BVF PARTNERS L P/IL

Direct Beneficial Owner

Large shareholder
660,000 -5.8%
5.25
US$3,465,000 		660,000 -5.8% 5.25 US$3,465,000
2009-09-21 2009-09-17 S Sale BVF PARTNERS L P/IL

Direct Beneficial Owner

Large shareholder
920,000 -7.5%
5.25
US$4,830,000 		920,000 -7.5% 5.25 US$4,830,000
2009-08-19 2009-08-18 B Purchase BARABE TIMOTHY C Non-Executive Director
784 +3.1%
5.26
US$4,124 		784 +3.1% 5.26 US$4,124
2009-08-19 2009-08-18 B Purchase LOBERG MICHAEL D Non-Executive Director
356 +0.6%
5.26
US$1,873 		356 +0.6% 5.26 US$1,873
2009-08-17 2009-08-13 B Purchase LOBERG MICHAEL D Non-Executive Director
88 +0.1%
5.65
US$497 		88 +0.1% 5.65 US$497
2009-08-06 2009-08-05 B Purchase BARABE TIMOTHY C Non-Executive Director
104 +0.4%
5.73
US$596 		104 +0.4% 5.73 US$596
2009-07-28 2009-07-24 B Purchase BARABE TIMOTHY C Non-Executive Director
206 +0.8%
5.82
US$1,199 		206 +0.8% 5.82 US$1,199
2009-07-28 2009-07-24 B Purchase LOBERG MICHAEL D Non-Executive Director
171 +0.3%
5.82
US$995 		171 +0.3% 5.82 US$995
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