United States Biotechnology & Medical Research

Aprea Therapeutics Inc (APRE)

Ticker: APRE Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
2.6
Hamill John P. SrVP/CFO/Prin Fin & Acct Ofcr Officer
Transaction date
Purchase
Price
430.12
Quantity 34,073 -47.8%
Value US$4,597,741
2.2
Gilad Oren President/CEO Executive Director
Transaction date
Purchase
Price
477.45
Quantity 79,843 +19.5%
Value US$318,037
1.8
Duey Marc Non-Executive Director
Transaction date
Purchase
Price
366.34
Quantity 65,859 +21.4%
Value US$401,203
2.6
Hamill John P. SrVP/CFO/Prin Fin & Acct Ofcr Officer
Transaction date
Purchase
Price
1.17
Quantity 5,000 +22.0%
Value US$5,825
2.2
Gilad Oren President/CEO Executive Director
Transaction date
Purchase
Price
1.80
Quantity 2,497 +0.7%
Value US$4,495
2.2
Gilad Oren President/CEO Executive Director
Transaction date
Purchase
Price
1.87
Quantity 3,003 +0.9%
Value US$5,616
2.2
Gilad Oren President/CEO Executive Director
Transaction date
Purchase
Price
3.92
Quantity 500 +0.2%
Value US$1,958
1.8
Duey Marc Non-Executive Director
Transaction date
Sale
Price
4.58
Quantity 6,462 -2.7%
Value US$29,583
1.8
Duey Marc Non-Executive Director
Transaction date
Purchase
Price
4.39
Quantity 30,000 +14.3%
Value US$131,700
2.2
Gilad Oren President/CEO Executive Director
Transaction date
Purchase
Price
2.90
Quantity 250 +0.1%
Value US$725
1.8
Duey Marc Non-Executive Director
Transaction date
Purchase
Price
2.58
Quantity 190 +0.1%
Value US$490
2.2
Gilad Oren President/CEO Executive Director
Transaction date
Purchase
Price
2.59
Quantity 1,000 +0.3%
Value US$2,590
2.6
Hamill John P. SrVP/CFO/Prin Fin & Acct Ofcr Officer
Transaction date
Purchase
Price
2.46
Quantity 50 +0.3%
Value US$123
2.9
Seizinger Bernd R. Non-Executive Director
Transaction date
Purchase
Price
2.68
Quantity 10,000 +28.8%
Value US$26,800
2.2
Gilad Oren President/CEO Executive Director
Transaction date
Purchase
Price
2.54
Quantity 150 +0.0%
Value US$381
2.6
Hamill John P. SrVP/CFO/Prin Fin & Acct Ofcr Officer
Transaction date
Purchase
Price
2.61
Quantity 450 +2.4%
Value US$1,174
2.6
Hamill John P. SrVP/CFO/Prin Fin & Acct Ofcr Officer
Transaction date
Purchase
Price
7.29
Quantity 1,010 +7.0%
Value US$7,363
2.9
Seizinger Bernd R. Non-Executive Director
Transaction date
Purchase
Price
7.29
Quantity 6,860 +25.6%
Value US$50,009
3.5
HENNEMAN JOHN B III Non-Executive Director
Transaction date
Purchase
Price
7.29
Quantity 6,860 +536.4%
Value US$50,009
2.2
Gilad Oren President, CEO Executive Director
Transaction date
Purchase
Price
7.29
Quantity 2,000 +0.6%
Value US$14,580
2.9
Seizinger Bernd R. Non-Executive Director
Transaction date
Purchase
Price
3.68
Quantity 6,029 +29.7%
Value US$22,192
2.9
Seizinger Bernd R. Non-Executive Director
Transaction date
Purchase
Price
3.63
Quantity 4,068 +25.1%
Value US$14,764
2.9
Seizinger Bernd R. Non-Executive Director
Transaction date
Purchase
Price
0.71
Quantity 50,000 +18.6%
Value US$35,500
2.2
SCHADE CHRISTIAN S Chairman & CEO Executive Director
Transaction date
Purchase
Price
0.64
Quantity 37,500 +14.7%
Value US$24,124
Attar Eyal C. SVP, Chief Medical Officer Officer
Transaction date
Planned sale
Price
1.73
Quantity 36,000 -43.4%
Value US$62,280
Korbel Gregory Alan SVP, Chief Business Officer Officer
Transaction date
Planned sale
Price
3.96
Quantity 27,500 -61.6%
Value US$108,900
Korbel Gregory Alan SVP, Chief Business Officer Officer
Transaction date
Planned sale
Price
5.00
Quantity 27,500 -61.6%
Value US$137,500
Korbel Gregory Alan SVP, Chief Business Officer Officer
Transaction date
Planned sale
Price
4.89
Quantity 27,500 -61.6%
Value US$134,475
Abrahmsen Lars B. SVP, Chief Scientific Officer Officer
Transaction date
Planned sale
Price
4.89
Quantity 50,000 -72.5%
Value US$244,500
3.2
Redmile Group, LLC Large shareholder
Transaction date
Sale
Price
5.80
Quantity 5,863 -0.3%
Value US$34,005
3.2
Redmile Group, LLC Large shareholder
Transaction date
Sale
Price
5.58
Quantity 494,137 -21.8%
Value US$2,757,284
3.6
5AM Ventures IV, L.P. Former 10% holder
Transaction date
Sale
Price
25.30
Quantity 175,000 -55.8%
Value US$4,427,500
3.2
KDev Investments AB Large shareholder
Transaction date
Sale
Price
34.55
Quantity 241,703 -10.8%
Value US$8,350,839
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Sale
Price
33.30
Quantity 19,836 -6.0%
Value US$660,539
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Sale
Price
33.30
Quantity 4,807 -6.0%
Value US$160,073
3.1
ROCKLAGE SCOTT M Non-Executive Director Large shareholder
Transaction date
Sale
Price
33.30
Quantity 4,807 -6.0%
Value US$160,073
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Sale
Price
33.30
Quantity 115,357 -6.0%
Value US$3,841,388
3.1
ROCKLAGE SCOTT M Non-Executive Director Large shareholder
Transaction date
Sale
Price
33.30
Quantity 115,357 -6.0%
Value US$3,841,388
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Sale
Price
28.75
Quantity 9,800 -10.8%
Value US$281,776
3.1
ROCKLAGE SCOTT M Non-Executive Director Large shareholder
Transaction date
Sale
Price
28.75
Quantity 9,800 -10.8%
Value US$281,776
3.1
ROCKLAGE SCOTT M Non-Executive Director Large shareholder
Transaction date
Sale
Price
28.75
Quantity 235,200 -10.8%
Value US$6,762,635
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Sale
Price
28.75
Quantity 235,200 -10.8%
Value US$6,762,635
3.1
ROCKLAGE SCOTT M Non-Executive Director
Transaction date
Sale
Price
35.15
Quantity 10,200 -10.1%
Value US$358,530
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Sale
Price
35.15
Quantity 10,200 -10.1%
Value US$358,530
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Sale
Price
35.15
Quantity 244,800 -10.1%
Value US$8,604,720
3.1
ROCKLAGE SCOTT M Non-Executive Director
Transaction date
Sale
Price
35.15
Quantity 244,800 -10.1%
Value US$8,604,720
3.2
KDev Investments AB Large shareholder
Transaction date
Sale
Price
31.25
Quantity 210,548 -8.6%
Value US$6,579,625
3.6
5AM Ventures IV, L.P. Large shareholder
Transaction date
Purchase
Price
15.00
Quantity 333,333 New position
Value US$4,999,995
3.2
Redmile Group, LLC Large shareholder
Transaction date
Purchase
Price
15.00
Quantity 400,000 +21.4%
Value US$6,000,000
Korbel Gregory Alan VP of Business Dev't
Transaction date
Purchase
Price
15.00
Quantity 500 New position
Value US$7,500
0.6
HealthCap VII, L.P. Large shareholder
Transaction date
Purchase
Price
15.00
Quantity 266,667 +12.7%
Value US$4,000,005
Coiante Scott M SVP, Chief Financial Officer
Transaction date
Purchase
Price
15.00
Quantity 2,500 New position
Value US$37,500
Attar Eyal C. SVP, Chief Medical Officer
Transaction date
Purchase
Price
15.00
Quantity 200 New position
Value US$3,000
Attar Eyal C. SVP, Chief Medical Officer
Transaction date
Purchase
Price
15.00
Quantity 200 New position
Value US$3,000
3.5
HENNEMAN JOHN B III
Transaction date
Purchase
Price
15.00
Quantity 5,000 New position
Value US$75,000
2.2
SCHADE CHRISTIAN S President & CEO
Transaction date
Purchase
Price
15.00
Quantity 5,000 New position
Value US$75,000
2.2
SCHADE CHRISTIAN S President & CEO
Transaction date
Purchase
Price
15.00
Quantity 1,000 New position
Value US$15,000
2.2
SCHADE CHRISTIAN S President & CEO
Transaction date
Purchase
Price
15.00
Quantity 1,000 New position
Value US$15,000
2.2
SCHADE CHRISTIAN S President & CEO
Transaction date
Purchase
Price
15.00
Quantity 1,000 New position
Value US$15,000
2.2
SCHADE CHRISTIAN S President & CEO
Transaction date
Purchase
Price
15.00
Quantity 1,000 New position
Value US$15,000
2.2
SCHADE CHRISTIAN S President & CEO
Transaction date
Purchase
Price
15.00
Quantity 1,000 New position
Value US$15,000
2.2
SCHADE CHRISTIAN S President & CEO
Transaction date
Purchase
Price
15.00
Quantity 1,000 New position
Value US$15,000
0.6
Christenson Johan
Transaction date
Purchase
Price
15.00
Quantity 266,667 +12.7%
Value US$4,000,005
Magni Guido
Transaction date
Purchase
Price
15.00
Quantity 6,500 New position
Value US$97,500
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-02-02 2026-01-30 B Purchase
2.6
Hamill John P.

SrVP/CFO/Prin Fin & Acct Ofcr

Officer
34,073 -47.8%
430.12
US$4,597,741 		34,073 -47.8% 430.12 US$4,597,741
2026-02-02 2026-01-30 B Purchase
2.2
Gilad Oren

President/CEO

Executive Director
79,843 +19.5%
477.45
US$318,037 		79,843 +19.5% 477.45 US$318,037
2025-12-11 2025-12-10 B Purchase
1.8
Duey Marc
Non-Executive Director
65,859 +21.4%
366.34
US$401,203 		65,859 +21.4% 366.34 US$401,203
2025-12-11 2025-12-10 B Purchase
2.6
Hamill John P.

SrVP/CFO/Prin Fin & Acct Ofcr

Officer
5,000 +22.0%
1.17
US$5,825 		5,000 +22.0% 1.17 US$5,825
2025-04-04 2025-04-03 B Purchase
2.2
Gilad Oren

President/CEO

Executive Director
2,497 +0.7%
1.80
US$4,495 		2,497 +0.7% 1.80 US$4,495
2025-04-04 2025-04-03 B Purchase
2.2
Gilad Oren

President/CEO

Executive Director
3,003 +0.9%
1.87
US$5,616 		3,003 +0.9% 1.87 US$5,616
2024-10-24 2024-10-23 B Purchase
2.2
Gilad Oren

President/CEO

Executive Director
500 +0.2%
3.92
US$1,958 		500 +0.2% 3.92 US$1,958
2024-10-25 2024-10-18 S Sale
1.8
Duey Marc
Non-Executive Director
6,462 -2.7%
4.58
US$29,583 		6,462 -2.7% 4.58 US$29,583
2024-10-17 2024-10-16 B Purchase
1.8
Duey Marc
Non-Executive Director
30,000 +14.3%
4.39
US$131,700 		30,000 +14.3% 4.39 US$131,700
2024-10-16 2024-10-15 B Purchase
2.2
Gilad Oren

President/CEO

Executive Director
250 +0.1%
2.90
US$725 		250 +0.1% 2.90 US$725
2024-10-16 2024-10-14 B Purchase
1.8
Duey Marc
Non-Executive Director
190 +0.1%
2.58
US$490 		190 +0.1% 2.58 US$490
2024-10-15 2024-10-14 B Purchase
2.2
Gilad Oren

President/CEO

Executive Director
1,000 +0.3%
2.59
US$2,590 		1,000 +0.3% 2.59 US$2,590
2024-10-16 2024-10-11 B Purchase
2.6
Hamill John P.

SrVP/CFO/Prin Fin & Acct Ofcr

Officer
50 +0.3%
2.46
US$123 		50 +0.3% 2.46 US$123
2024-10-15 2024-10-11 B Purchase
2.9
Seizinger Bernd R.
Non-Executive Director
10,000 +28.8%
2.68
US$26,800 		10,000 +28.8% 2.68 US$26,800
2024-10-15 2024-10-10 B Purchase
2.2
Gilad Oren

President/CEO

Executive Director
150 +0.0%
2.54
US$381 		150 +0.0% 2.54 US$381
2024-10-15 2024-10-10 B Purchase
2.6
Hamill John P.

SrVP/CFO/Prin Fin & Acct Ofcr

Officer
450 +2.4%
2.61
US$1,174 		450 +2.4% 2.61 US$1,174
2024-03-14 2024-03-13 B Purchase
2.6
Hamill John P.

SrVP/CFO/Prin Fin & Acct Ofcr

Officer
1,010 +7.0%
7.29
US$7,363 		1,010 +7.0% 7.29 US$7,363
2024-03-14 2024-03-13 B Purchase
2.9
Seizinger Bernd R.
Non-Executive Director
6,860 +25.6%
7.29
US$50,009 		6,860 +25.6% 7.29 US$50,009
2024-03-14 2024-03-13 B Purchase
3.5
HENNEMAN JOHN B III
Non-Executive Director
6,860 +536.4%
7.29
US$50,009 		6,860 +536.4% 7.29 US$50,009
2024-03-14 2024-03-13 B Purchase
2.2
Gilad Oren

President, CEO

Executive Director
2,000 +0.6%
7.29
US$14,580 		2,000 +0.6% 7.29 US$14,580
2023-06-08 2023-06-07 B Purchase
2.9
Seizinger Bernd R.
Non-Executive Director
6,029 +29.7%
3.68
US$22,192 		6,029 +29.7% 3.68 US$22,192
2023-06-08 2023-06-06 B Purchase
2.9
Seizinger Bernd R.
Non-Executive Director
4,068 +25.1%
3.63
US$14,764 		4,068 +25.1% 3.63 US$14,764
2022-05-19 2022-05-18 B Purchase
2.9
Seizinger Bernd R.
Non-Executive Director
50,000 +18.6%
0.71
US$35,500 		50,000 +18.6% 0.71 US$35,500
2022-05-19 2022-05-18 B Purchase
2.2
SCHADE CHRISTIAN S

Chairman & CEO

Executive Director
37,500 +14.7%
0.64
US$24,124 		37,500 +14.7% 0.64 US$24,124
2022-03-01 2022-02-28 PlS Planned sale
Attar Eyal C.

SVP, Chief Medical Officer

Officer
36,000 -43.4%
1.73
US$62,280 		36,000 -43.4% 1.73 US$62,280
2021-12-03 2021-12-01 PlS Planned sale
Korbel Gregory Alan

SVP, Chief Business Officer

Officer
27,500 -61.6%
3.96
US$108,900 		27,500 -61.6% 3.96 US$108,900
2021-11-03 2021-11-01 PlS Planned sale
Korbel Gregory Alan

SVP, Chief Business Officer

Officer
27,500 -61.6%
5.00
US$137,500 		27,500 -61.6% 5.00 US$137,500
2021-10-05 2021-10-01 PlS Planned sale
Korbel Gregory Alan

SVP, Chief Business Officer

Officer
27,500 -61.6%
4.89
US$134,475 		27,500 -61.6% 4.89 US$134,475
2021-10-05 2021-10-01 PlS Planned sale
Abrahmsen Lars B.

SVP, Chief Scientific Officer

Officer
50,000 -72.5%
4.89
US$244,500 		50,000 -72.5% 4.89 US$244,500
2021-02-16 2020-12-28 S Sale
3.2
Redmile Group, LLC
Large shareholder
5,863 -0.3%
5.80
US$34,005 		5,863 -0.3% 5.80 US$34,005
2021-02-16 2020-12-28 S Sale
3.2
Redmile Group, LLC
Large shareholder
494,137 -21.8%
5.58
US$2,757,284 		494,137 -21.8% 5.58 US$2,757,284
2020-10-07 2020-10-05 S Sale
3.6
5AM Ventures IV, L.P.

Former 10% holder
175,000 -55.8%
25.30
US$4,427,500 		175,000 -55.8% 25.30 US$4,427,500
2020-07-07 2020-07-07 S Sale
3.2
KDev Investments AB
Large shareholder
241,703 -10.8%
34.55
US$8,350,839 		241,703 -10.8% 34.55 US$8,350,839
2020-06-18 2020-06-16 S Sale
3.6
5AM Ventures IV, L.P.
Large shareholder
19,836 -6.0%
33.30
US$660,539 		19,836 -6.0% 33.30 US$660,539
2020-06-18 2020-06-16 S Sale
3.6
5AM Ventures IV, L.P.
Large shareholder
4,807 -6.0%
33.30
US$160,073 		4,807 -6.0% 33.30 US$160,073
2020-06-18 2020-06-16 S Sale
3.1
ROCKLAGE SCOTT M
Non-Executive Director Large shareholder
4,807 -6.0%
33.30
US$160,073 		4,807 -6.0% 33.30 US$160,073
2020-06-18 2020-06-16 S Sale
3.6
5AM Ventures IV, L.P.
Large shareholder
115,357 -6.0%
33.30
US$3,841,388 		115,357 -6.0% 33.30 US$3,841,388
2020-06-18 2020-06-16 S Sale
3.1
ROCKLAGE SCOTT M
Non-Executive Director Large shareholder
115,357 -6.0%
33.30
US$3,841,388 		115,357 -6.0% 33.30 US$3,841,388
2020-06-15 2020-06-11 S Sale
3.6
5AM Ventures IV, L.P.
Large shareholder
9,800 -10.8%
28.75
US$281,776 		9,800 -10.8% 28.75 US$281,776
2020-06-15 2020-06-11 S Sale
3.1
ROCKLAGE SCOTT M
Non-Executive Director Large shareholder
9,800 -10.8%
28.75
US$281,776 		9,800 -10.8% 28.75 US$281,776
2020-06-15 2020-06-11 S Sale
3.1
ROCKLAGE SCOTT M
Non-Executive Director Large shareholder
235,200 -10.8%
28.75
US$6,762,635 		235,200 -10.8% 28.75 US$6,762,635
2020-06-15 2020-06-11 S Sale
3.6
5AM Ventures IV, L.P.
Large shareholder
235,200 -10.8%
28.75
US$6,762,635 		235,200 -10.8% 28.75 US$6,762,635
2020-05-21 2020-05-19 S Sale
3.1
ROCKLAGE SCOTT M
Non-Executive Director
10,200 -10.1%
35.15
US$358,530 		10,200 -10.1% 35.15 US$358,530
2020-05-21 2020-05-19 S Sale
3.6
5AM Ventures IV, L.P.
Large shareholder
10,200 -10.1%
35.15
US$358,530 		10,200 -10.1% 35.15 US$358,530
2020-05-21 2020-05-19 S Sale
3.6
5AM Ventures IV, L.P.
Large shareholder
244,800 -10.1%
35.15
US$8,604,720 		244,800 -10.1% 35.15 US$8,604,720
2020-05-21 2020-05-19 S Sale
3.1
ROCKLAGE SCOTT M
Non-Executive Director
244,800 -10.1%
35.15
US$8,604,720 		244,800 -10.1% 35.15 US$8,604,720
2020-04-15 2020-04-13 S Sale
3.2
KDev Investments AB
Large shareholder
210,548 -8.6%
31.25
US$6,579,625 		210,548 -8.6% 31.25 US$6,579,625
2019-10-09 2019-10-07 B Purchase
3.6
5AM Ventures IV, L.P.
Large shareholder
333,333 New position
15.00
US$4,999,995 		333,333 New position 15.00 US$4,999,995
2019-10-08 2019-10-07 B Purchase
3.2
Redmile Group, LLC
Large shareholder
400,000 +21.4%
15.00
US$6,000,000 		400,000 +21.4% 15.00 US$6,000,000
2019-10-07 2019-10-07 B Purchase
Korbel Gregory Alan

VP of Business Dev't
500 New position
15.00
US$7,500 		500 New position 15.00 US$7,500
2019-10-07 2019-10-07 B Purchase
0.6
HealthCap VII, L.P.
Large shareholder
266,667 +12.7%
15.00
US$4,000,005 		266,667 +12.7% 15.00 US$4,000,005
2019-10-07 2019-10-07 B Purchase
Coiante Scott M

SVP, Chief Financial Officer
2,500 New position
15.00
US$37,500 		2,500 New position 15.00 US$37,500
2019-10-07 2019-10-07 B Purchase
Attar Eyal C.

SVP, Chief Medical Officer
200 New position
15.00
US$3,000 		200 New position 15.00 US$3,000
2019-10-07 2019-10-07 B Purchase
Attar Eyal C.

SVP, Chief Medical Officer
200 New position
15.00
US$3,000 		200 New position 15.00 US$3,000
2019-10-07 2019-10-07 B Purchase
3.5
HENNEMAN JOHN B III
5,000 New position
15.00
US$75,000 		5,000 New position 15.00 US$75,000
2019-10-07 2019-10-07 B Purchase
2.2
SCHADE CHRISTIAN S

President & CEO
5,000 New position
15.00
US$75,000 		5,000 New position 15.00 US$75,000
2019-10-07 2019-10-07 B Purchase
2.2
SCHADE CHRISTIAN S

President & CEO
1,000 New position
15.00
US$15,000 		1,000 New position 15.00 US$15,000
2019-10-07 2019-10-07 B Purchase
2.2
SCHADE CHRISTIAN S

President & CEO
1,000 New position
15.00
US$15,000 		1,000 New position 15.00 US$15,000
2019-10-07 2019-10-07 B Purchase
2.2
SCHADE CHRISTIAN S

President & CEO
1,000 New position
15.00
US$15,000 		1,000 New position 15.00 US$15,000
2019-10-07 2019-10-07 B Purchase
2.2
SCHADE CHRISTIAN S

President & CEO
1,000 New position
15.00
US$15,000 		1,000 New position 15.00 US$15,000
2019-10-07 2019-10-07 B Purchase
2.2
SCHADE CHRISTIAN S

President & CEO
1,000 New position
15.00
US$15,000 		1,000 New position 15.00 US$15,000
2019-10-07 2019-10-07 B Purchase
2.2
SCHADE CHRISTIAN S

President & CEO
1,000 New position
15.00
US$15,000 		1,000 New position 15.00 US$15,000
2019-10-07 2019-10-07 B Purchase
Versant V Luxco S.a r.l.
333,333 New position
15.00
US$4,999,995 		333,333 New position 15.00 US$4,999,995
2019-10-07 2019-10-07 B Purchase
0.6
Christenson Johan
266,667 +12.7%
15.00
US$4,000,005 		266,667 +12.7% 15.00 US$4,000,005
2019-10-07 2019-10-07 B Purchase
0.9
Versant Vantage I, L.P.
333,333 New position
15.00
US$4,999,995 		333,333 New position 15.00 US$4,999,995
2019-10-07 2019-10-07 B Purchase
Magni Guido
6,500 New position
15.00
US$97,500 		6,500 New position 15.00 US$97,500
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