Seizinger Bernd R.

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2024-10-15	2024-10-11	Aprea Therapeutics Inc (APRE)	B Purchase	10,000 +28.8% 2.68 USD 26,800	10,000 +28.8%	2.68	USD 26,800
2024-03-14	2024-03-13	Aprea Therapeutics Inc (APRE)	B Purchase	6,860 +25.6% 7.29 USD 50,009	6,860 +25.6%	7.29	USD 50,009
2023-09-25	2023-09-22	Aptose Biosciences Inc (APS)	B Purchase	17,000 +inf% 3.14 USD 53,380	17,000 +inf%	3.14	USD 53,380
2023-06-08	2023-06-07	Aprea Therapeutics Inc (APRE)	B Purchase	6,029 +29.7% 3.68 USD 22,192	6,029 +29.7%	3.68	USD 22,192
2023-06-08	2023-06-06	Aprea Therapeutics Inc (APRE)	B Purchase	4,068 +25.1% 3.63 USD 14,764	4,068 +25.1%	3.63	USD 14,764
2022-05-19	2022-05-18	Aprea Therapeutics Inc (APRE)	B Purchase	50,000 +18.6% 0.71 USD 35,500	50,000 +18.6%	0.71	USD 35,500