|
2025-01-03 |
2024-12-31 |
S
Sale
|
Non-Executive Director
|
1,609
+49.8%
233.97
US$2,911,950
|
1,609
+49.8%
|
233.97
|
US$2,911,950
|
|
|
2025-01-03 |
2024-12-31 |
S
Sale
|
Non-Executive Director
|
61,112
-27.0%
239.02
US$167,197
|
61,112
-27.0%
|
239.02
|
US$167,197
|
|
|
2023-09-05 |
2023-09-01 |
PlS
Planned sale
|
Chief Executive Officer
Executive Director
|
11,579
+1.3%
48.12
US$4,522,844
|
11,579
+1.3%
|
48.12
|
US$4,522,844
|
|
|
2023-09-01 |
2023-09-01 |
PrS
Proposed sale
|
Officer
Officer
|
70,401
0.14
US$9,504
|
70,401
|
0.14
|
US$9,504
|
|
|
2022-12-01 |
2022-11-29 |
B
Purchase
|
Non-Executive Director
|
750,000
+17.6%
0.65
US$487,500
|
750,000
+17.6%
|
0.65
|
US$487,500
|
|
|
2022-12-01 |
2022-11-29 |
B
Purchase
|
Non-Executive Director
|
1,250,000
+inf%
0.65
US$812,500
|
1,250,000
+inf%
|
0.65
|
US$812,500
|
|
|
2021-11-17 |
2021-11-17 |
B
Purchase
|
Chief Executive Officer
Executive Director
|
9,116
+1.0%
1.40
US$12,762
|
9,116
+1.0%
|
1.40
|
US$12,762
|
|
|
2021-11-17 |
2021-11-16 |
B
Purchase
|
Chief Executive Officer
Executive Director
|
884
+0.1%
1.40
US$1,238
|
884
+0.1%
|
1.40
|
US$1,238
|
|
|
2021-10-04 |
2021-09-29 |
B
Purchase
|
Non-Executive Director
|
100,000
+16.5%
1.91
US$191,000
|
100,000
+16.5%
|
1.91
|
US$191,000
|
|
|
2021-09-03 |
2021-09-02 |
B
Purchase
|
Non-Executive Director
|
54,492
+1.3%
1.73
US$94,271
|
54,492
+1.3%
|
1.73
|
US$94,271
|
|
|
2021-09-03 |
2021-09-02 |
B
Purchase
|
Non-Executive Director
|
20,508
+1.7%
1.73
US$35,479
|
20,508
+1.7%
|
1.73
|
US$35,479
|
|
|
2021-01-12 |
2021-01-08 |
PlS
Planned sale
|
EVP, GM Gene Therapy
Officer
|
27,894
-12.3%
3.12
US$87,029
|
27,894
-12.3%
|
3.12
|
US$87,029
|
|
|
2021-01-12 |
2021-01-08 |
PlS
Planned sale
|
SVP, Treasurer & CAO
Officer
|
18,020
-22.0%
3.09
US$55,682
|
18,020
-22.0%
|
3.09
|
US$55,682
|
|
|
2021-01-12 |
2021-01-08 |
PlS
Planned sale
|
General Counsel and Secretary
Officer
|
26,500
-16.6%
3.12
US$82,680
|
26,500
-16.6%
|
3.12
|
US$82,680
|
|
|
2021-01-06 |
2021-01-04 |
PlS
Planned sale
|
EVP, GM Cell Therapy
Officer
|
21,620
-9.5%
2.72
US$58,806
|
21,620
-9.5%
|
2.72
|
US$58,806
|
|
|
2021-01-06 |
2021-01-04 |
PlS
Planned sale
|
President and CEO
Executive Director
|
105,693
-5.5%
2.71
US$286,428
|
105,693
-5.5%
|
2.71
|
US$286,428
|
|
|
2020-01-03 |
2020-01-02 |
PlS
Planned sale
|
President
Officer
|
22,394
-10.3%
4.55
US$101,893
|
22,394
-10.3%
|
4.55
|
US$101,893
|
|
|
2020-01-03 |
2020-01-02 |
PlS
Planned sale
|
EVP, GM Gene Therapy
Officer
|
27,923
-13.8%
4.55
US$127,050
|
27,923
-13.8%
|
4.55
|
US$127,050
|
|
|
2020-01-03 |
2020-01-02 |
PlS
Planned sale
|
EVP, GM Cell Therapy
Officer
|
24,890
-12.5%
4.55
US$113,250
|
24,890
-12.5%
|
4.55
|
US$113,250
|
|
|
2020-01-03 |
2020-01-02 |
PlS
Planned sale
|
General Counsel and Secretary
Officer
|
16,853
-14.3%
4.55
US$76,681
|
16,853
-14.3%
|
4.55
|
US$76,681
|
|
|
2020-01-03 |
2020-01-02 |
PlS
Planned sale
|
SVP, Treasurer & CAO
Officer
|
21,570
-25.2%
4.55
US$98,144
|
21,570
-25.2%
|
4.55
|
US$98,144
|
|
|
2019-12-31 |
2019-12-30 |
PlS
Planned sale
|
Cooper Laurence James Neil
Chief Executive Officer
Executive Director
|
110,694
-6.0%
4.88
US$540,187
|
110,694
-6.0%
|
4.88
|
US$540,187
|
|
|
2019-11-27 |
2019-11-26 |
PlS
Planned sale
|
SVP, Treasurer & CAO
|
11,667
-12.0%
5.25
US$61,252
|
11,667
-12.0%
|
5.25
|
US$61,252
|
|
|
2017-11-09 |
2017-11-08 |
B
Purchase
|
Cooper Laurence James Neil
Chief Executive Officer
|
6,440
+0.6%
4.68
US$30,139
|
6,440
+0.6%
|
4.68
|
US$30,139
|
|
|
2017-11-09 |
2017-11-08 |
B
Purchase
|
MAUNEY DAVID M MD
EVP and Chief Business Officer
|
4,270
+7.9%
4.68
US$19,984
|
4,270
+7.9%
|
4.68
|
US$19,984
|
|
|
2015-11-23 |
2015-11-19 |
S
Sale
|
BELBEL CAESAR J
COO, CLO, and Secretary
Officer
|
153,333
-72.1%
12.84
US$1,968,796
|
153,333
-72.1%
|
12.84
|
US$1,968,796
|
|
|
2015-06-11 |
2015-06-09 |
S
Sale
|
LEBEL FRANCOIS
Executive Vice President R&D
Officer
|
50,000
-100.0%
10.12
US$506,000
|
50,000
-100.0%
|
10.12
|
US$506,000
|
|
|
2015-06-05 |
2015-06-04 |
S
Sale
|
BRENNAN MURRAY
Non-Executive Director
|
5,837
-31.8%
9.55
US$55,743
|
5,837
-31.8%
|
9.55
|
US$55,743
|
|
|
2015-06-05 |
2015-06-03 |
S
Sale
|
Lafond Kevin G
Vice Pres., Treasurer, & CAO
Officer
|
27,500
-100.0%
9.70
US$266,750
|
27,500
-100.0%
|
9.70
|
US$266,750
|
|
|
2015-06-05 |
2015-06-03 |
S
Sale
|
Lafond Kevin G
Vice Pres., Treasurer, & CAO
Officer
|
3,334
-100.0%
9.70
US$32,340
|
3,334
-100.0%
|
9.70
|
US$32,340
|
|
|
2015-06-05 |
2015-06-03 |
S
Sale
|
BRENNAN MURRAY
Non-Executive Director
|
34,163
-65.1%
9.72
US$332,064
|
34,163
-65.1%
|
9.72
|
US$332,064
|
|
|
2015-06-05 |
2015-06-03 |
S
Sale
|
Lafond Kevin G
Vice Pres., Treasurer, & CAO
Officer
|
26,666
-100.0%
9.60
US$255,994
|
26,666
-100.0%
|
9.60
|
US$255,994
|
|
|
2015-02-10 |
2015-02-09 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
1,440,000
+8.8%
8.75
US$12,600,000
|
1,440,000
+8.8%
|
8.75
|
US$12,600,000
|
|
|
2013-10-31 |
2013-10-29 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
2,857,143
+21.1%
3.50
US$10,000,000
|
2,857,143
+21.1%
|
3.50
|
US$10,000,000
|
|
|
2012-01-23 |
2012-01-20 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
1,923,075
+24.1%
5.20
US$9,999,990
|
1,923,075
+24.1%
|
5.20
|
US$9,999,990
|
|
|
2011-08-25 |
2011-08-23 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
38,294
+2.9%
4.99
US$191,087
|
38,294
+2.9%
|
4.99
|
US$191,087
|
|
|
2011-08-22 |
2011-08-22 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
110,792
+9.3%
4.91
US$543,989
|
110,792
+9.3%
|
4.91
|
US$543,989
|
|
|
2011-08-22 |
2011-08-19 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
197,376
+19.7%
4.91
US$969,116
|
197,376
+19.7%
|
4.91
|
US$969,116
|
|
|
2011-08-22 |
2011-08-18 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
153,478
+18.1%
4.95
US$759,716
|
153,478
+18.1%
|
4.95
|
US$759,716
|
|
|
2011-08-11 |
2011-08-10 |
B
Purchase
|
Fowler Wyche
Non-Executive Director
|
5,000
+7.4%
5.19
US$25,926
|
5,000
+7.4%
|
5.19
|
US$25,926
|
|
|
2011-08-09 |
2011-08-09 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
285,518
+50.9%
5.13
US$1,464,707
|
285,518
+50.9%
|
5.13
|
US$1,464,707
|
|
|
2011-08-09 |
2011-08-08 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
444,892
+383.2%
4.58
US$2,037,605
|
444,892
+383.2%
|
4.58
|
US$2,037,605
|
|
|
2011-08-09 |
2011-08-05 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
116,112
+inf%
4.65
US$539,921
|
116,112
+inf%
|
4.65
|
US$539,921
|
|
|
2011-02-07 |
2011-02-03 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
1,910,000
+31.5%
5.75
US$10,982,500
|
1,910,000
+31.5%
|
5.75
|
US$10,982,500
|
|
|
2011-01-14 |
2011-01-12 |
B
Purchase
|
KIRK RANDAL J
Non-Executive Director
Large shareholder
|
2,426,235
+inf%
4.80
US$11,645,928
|
2,426,235
+inf%
|
4.80
|
US$11,645,928
|
|
|
2009-12-11 |
2009-12-09 |
B
Purchase
|
MCINERNEY TIMOTHY
Non-Executive Director
|
50,000
+31.6%
3.10
US$155,000
|
50,000
+31.6%
|
3.10
|
US$155,000
|
|
|
2009-12-11 |
2009-12-09 |
B
Purchase
|
CANNON JAMES ANTHONY
Non-Executive Director
|
175,000
+388.9%
3.10
US$542,500
|
175,000
+388.9%
|
3.10
|
US$542,500
|
|
|
2009-12-10 |
2009-12-08 |
B
Purchase
|
ESSEX WOODLANDS HEALTH VENTURES FUND VI L P
Large shareholder
|
129,000
+5.8%
3.10
US$399,900
|
129,000
+5.8%
|
3.10
|
US$399,900
|
|
|
2009-12-10 |
2009-09-15 |
B
Purchase
|
ESSEX WOODLANDS HEALTH VENTURES FUND VI L P
Large shareholder
|
328,766
+17.2%
1.83
US$599,998
|
328,766
+17.2%
|
1.83
|
US$599,998
|
|
|
2009-09-17 |
2009-09-15 |
B
Purchase
|
MCINERNEY TIMOTHY
Non-Executive Director
|
50,000
+63.9%
1.83
US$91,250
|
50,000
+63.9%
|
1.83
|
US$91,250
|
|
|
2007-12-10 |
2007-12-07 |
B
Purchase
|
LEWIS JONATHAN
CEO
Executive Director
|
3,000
+150.0%
3.00
US$8,990
|
3,000
+150.0%
|
3.00
|
US$8,990
|
|
|
2007-03-22 |
2007-03-15 |
B
Purchase
|
MCINERNEY TIMOTHY
Non-Executive Director
|
4,000
+6.8%
5.00
US$20,000
|
4,000
+6.8%
|
5.00
|
US$20,000
|
|
|
2007-03-14 |
2007-03-12 |
B
Purchase
|
LEWIS JONATHAN
CEO
Executive Director
|
2,000
+inf%
4.95
US$9,900
|
2,000
+inf%
|
4.95
|
US$9,900
|
|