Akcea Therapeutics Inc (AKCA)

Healthcare Pharmaceuticals & Medical Research Pharmaceuticals

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Ticker: AKCA Exchange: NSM

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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale

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Value bought

Value sold

Net insiders buying

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other

Notification date	Transaction date	B/S Transaction type	Insider and/or position	Nb. shares Price Value	Number of shares	Price	Total value	Details
2020-10-14	2020-10-10	B Purchase	IONIS PHARMACEUTICALS INC Major owner	21,237,715 +27.6% 18.15 385,464,527 USD	21,237,715 +27.6%	18.15	385,464,527 USD
2020-09-24	2020-09-22	S Sale	McDevitt Damien Chief Executive Officer Executive Director	8,709 -3.5% 18.12 157,807 USD	8,709 -3.5%	18.12	157,807 USD
2020-09-24	2020-09-22	S Sale	Jenne Kyle Chief Commercial Officer Officer	720 -1.4% 18.12 13,046 USD	720 -1.4%	18.12	13,046 USD
2020-09-24	2020-09-22	S Sale	Patterson Joshua F. General Counsel Officer	319 -1.2% 18.12 5,780 USD	319 -1.2%	18.12	5,780 USD
2020-07-20	2020-07-17	S Sale	Patterson Joshua F. General Counsel Officer	263 -1.0% 12.50 3,288 USD	263 -1.0%	12.50	3,288 USD
2020-03-25	2020-03-23	S Sale	Patterson Joshua F. General Counsel Officer	335 -2.2% 11.76 3,938 USD	335 -2.2%	11.76	3,938 USD
2020-03-25	2020-03-23	S Sale	O'Dea Louis Chief Medical Officer Officer	3,198 -4.9% 11.75 37,579 USD	3,198 -4.9%	11.75	37,579 USD
2020-03-25	2020-03-23	S Sale	McDevitt Damien Chief Executive Officer Executive Director	9,417 -3.7% 11.75 110,649 USD	9,417 -3.7%	11.75	110,649 USD
2020-03-25	2020-03-23	S Sale	Jenne Kyle Chief Commercial Officer Officer	779 -1.5% 11.75 9,153 USD	779 -1.5%	11.75	9,153 USD
2019-07-17	2019-07-15	S Sale	Boyce Sarah President Executive Director	1,819 -8.4% 23.52 42,783 USD	1,819 -8.4%	23.52	42,783 USD
2019-04-09	2019-04-08	PS Planned sale	Soteropoulos Paula Chief Executive Officer Executive Director	1,787 -100.0% 32.17 57,480 USD	1,787 -100.0%	32.17	57,480 USD
2019-04-09	2019-04-08	PS Planned sale	Goldberg Jeff Marc Chief Operating Officer	20,000 -87.4% 31.72 634,418 USD	20,000 -87.4%	31.72	634,418 USD
2019-04-09	2019-04-05	PS Planned sale	Soteropoulos Paula Chief Executive Officer Executive Director	30,000 -100.0% 32.11 963,300 USD	30,000 -100.0%	32.11	963,300 USD
2019-04-09	2019-04-05	PS Planned sale	Goldberg Jeff Marc Chief Operating Officer	30,000 -91.2% 31.71 951,300 USD	30,000 -91.2%	31.71	951,300 USD
2019-03-07	2019-03-06	PS Planned sale	Soteropoulos Paula Chief Executive Officer Executive Director	18,386 -100.0% 32.14 590,856 USD	18,386 -100.0%	32.14	590,856 USD
2018-04-19	2018-04-17	B Purchase	IONIS PHARMACEUTICALS INC Major owner	10,666,666 +20.0% 18.75 199,999,988 USD	10,666,666 +20.0%	18.75	199,999,988 USD
2017-07-21	2017-07-19	B Purchase	IONIS PHARMACEUTICALS INC Major owner	3,125,000 +7.4% 8.00 25,000,000 USD	3,125,000 +7.4%	8.00	25,000,000 USD