|
2021-06-23 |
2021-06-21 |
PlS
Planned sale
|
Chief Commercial Officer
Officer
|
20,347
+11.0%
133.96
US$3,342,443
|
20,347
+11.0%
|
133.96
|
US$3,342,443
|
|
|
2021-06-08 |
2021-06-07 |
PlS
Planned sale
|
Non-Executive Director
|
92,982
+33.7%
43.62
US$2,895,988
|
92,982
+33.7%
|
43.62
|
US$2,895,988
|
|
|
2021-03-23 |
2021-03-22 |
S
Sale
|
Chief Financial Officer
Officer
|
23,552
-45.9%
168.30
US$1,754,007
|
23,552
-45.9%
|
168.30
|
US$1,754,007
|
|
|
2021-03-23 |
2021-03-22 |
S
Sale
|
Chief Commercial Officer
Officer
|
1,051
-0.6%
5.50
US$5,780
|
1,051
-0.6%
|
5.50
|
US$5,780
|
|
|
2021-03-15 |
2021-03-11 |
B
Purchase
|
Non-Executive Director
|
5,975
+59.8%
5.06
US$30,234
|
5,975
+59.8%
|
5.06
|
US$30,234
|
|
|
2021-02-01 |
2021-02-01 |
S
Sale
|
Chief Financial Officer
Officer
|
3,821
-5.0%
6.36
US$24,302
|
3,821
-5.0%
|
6.36
|
US$24,302
|
|
|
2021-02-01 |
2021-02-01 |
PlS
Planned sale
|
Chief Commercial Officer
Officer
|
4,514
-4.5%
6.39
US$28,844
|
4,514
-4.5%
|
6.39
|
US$28,844
|
|
|
2021-01-22 |
2021-01-20 |
S
Sale
|
Chief Financial Officer
Officer
|
2,630
-3.3%
4.41
US$11,598
|
2,630
-3.3%
|
4.41
|
US$11,598
|
|
|
2020-11-02 |
2020-11-02 |
S
Sale
|
Chief Financial Officer
Officer
|
2,050
-2.5%
3.21
US$6,580
|
2,050
-2.5%
|
3.21
|
US$6,580
|
|
|
2020-01-23 |
2020-01-21 |
S
Sale
|
Chief Financial Officer
|
1,269
-1.8%
5.92
US$7,512
|
1,269
-1.8%
|
5.92
|
US$7,512
|
|
|
2019-09-23 |
2019-09-20 |
S
Sale
|
Chief Financial Officer
|
1,584
-3.2%
6.91
US$10,945
|
1,584
-3.2%
|
6.91
|
US$10,945
|
|
|
2019-07-23 |
2019-07-22 |
S
Sale
|
Chief Accounting Officer
|
1,082
-2.2%
6.00
US$6,492
|
1,082
-2.2%
|
6.00
|
US$6,492
|
|
|
2019-06-21 |
2019-06-20 |
PlS
Planned sale
|
CBO, GC & Compliance Officer
|
940
-1.5%
5.35
US$5,029
|
940
-1.5%
|
5.35
|
US$5,029
|
|
|
2019-03-21 |
2019-03-20 |
S
Sale
|
Chief Executive Officer
Executive Director
|
6,319
-3.5%
7.99
US$50,489
|
6,319
-3.5%
|
7.99
|
US$50,489
|
|
|
2019-03-21 |
2019-03-20 |
S
Sale
|
CBO, GC & Compliance Officer
|
1,792
-5.4%
7.99
US$14,318
|
1,792
-5.4%
|
7.99
|
US$14,318
|
|
|
2019-03-21 |
2019-03-20 |
S
Sale
|
Chief Financial Officer
|
857
-3.4%
7.99
US$6,847
|
857
-3.4%
|
7.99
|
US$6,847
|
|
|
2019-03-21 |
2019-03-20 |
S
Sale
|
Chief Accounting Officer
|
1,185
-3.9%
8.00
US$9,480
|
1,185
-3.9%
|
8.00
|
US$9,480
|
|
|
2019-03-21 |
2019-03-20 |
S
Sale
|
Chief Medical Officer
|
2,374
-11.0%
8.00
US$18,992
|
2,374
-11.0%
|
8.00
|
US$18,992
|
|
|
2018-12-26 |
2018-12-20 |
PlS
Planned sale
|
Chief Accounting Officer
Officer
|
228
-1.2%
7.51
US$1,712
|
228
-1.2%
|
7.51
|
US$1,712
|
|
|
2018-12-21 |
2018-12-20 |
PlS
Planned sale
|
Rhodes Jennifer J
CBO, GC & Compliance Officer
Officer
|
425
-1.3%
7.52
US$3,196
|
425
-1.3%
|
7.52
|
US$3,196
|
|
|
2018-11-08 |
2018-11-07 |
B
Purchase
|
Went Gregory T
Chief Executive Officer
Executive Director
|
3,850
+2.0%
12.98
US$49,956
|
3,850
+2.0%
|
12.98
|
US$49,956
|
|
|
2018-09-21 |
2018-09-21 |
S
Sale
|
Chief Financial Officer
Officer
|
1,665
-6.1%
19.18
US$31,935
|
1,665
-6.1%
|
19.18
|
US$31,935
|
|
|
2018-06-22 |
2018-06-21 |
PlS
Planned sale
|
CBO, GC & Compliance Officer
Officer
|
1,002
-2.9%
25.48
US$25,531
|
1,002
-2.9%
|
25.48
|
US$25,531
|
|
|
2018-06-22 |
2018-06-21 |
PlS
Planned sale
|
KING RICHARD
Chief Operating Officer
|
2,501
-4.9%
25.48
US$63,725
|
2,501
-4.9%
|
25.48
|
US$63,725
|
|
|
2018-03-22 |
2018-03-21 |
S
Sale
|
Rhodes Jennifer J
CBO, GC & Compliance Officer
|
982
-2.8%
25.89
US$25,424
|
982
-2.8%
|
25.89
|
US$25,424
|
|
|
2018-03-22 |
2018-03-21 |
S
Sale
|
Chief Executive Officer
Executive Director
|
4,541
-2.4%
25.75
US$116,931
|
4,541
-2.4%
|
25.75
|
US$116,931
|
|
|
2018-03-22 |
2018-03-21 |
S
Sale
|
Chief Accounting Officer
|
567
-3.1%
25.98
US$14,731
|
567
-3.1%
|
25.98
|
US$14,731
|
|
|
2018-03-22 |
2018-03-21 |
S
Sale
|
Patni Rajiv
Chief Medical Officer
|
1,252
-5.5%
25.94
US$32,477
|
1,252
-5.5%
|
25.94
|
US$32,477
|
|
|
2017-12-21 |
2017-12-21 |
PlS
Planned sale
|
Rhodes Jennifer J
CBO, GC & Compliance Officer
|
440
-1.5%
32.30
US$14,212
|
440
-1.5%
|
32.30
|
US$14,212
|
|
|
2017-06-22 |
2017-06-21 |
PlS
Planned sale
|
CBO, GC & Compliance Officer
|
1,041
-3.5%
17.53
US$18,254
|
1,041
-3.5%
|
17.53
|
US$18,254
|
|
|
2017-06-21 |
2017-06-21 |
S
Sale
|
GREAT POINT PARTNERS LLC
Large shareholder
|
10,000
-0.4%
17.44
US$174,365
|
10,000
-0.4%
|
17.44
|
US$174,365
|
|
|
2017-06-21 |
2017-06-20 |
S
Sale
|
GREAT POINT PARTNERS LLC
Large shareholder
|
20,000
-0.9%
17.35
US$346,934
|
20,000
-0.9%
|
17.35
|
US$346,934
|
|
|
2017-06-21 |
2017-06-19 |
S
Sale
|
GREAT POINT PARTNERS LLC
Large shareholder
|
350,000
-13.5%
17.05
US$5,967,675
|
350,000
-13.5%
|
17.05
|
US$5,967,675
|
|
|
2017-03-22 |
2017-03-21 |
S
Sale
|
Patni Rajiv
Chief Medical Officer
|
733
-5.1%
17.04
US$12,490
|
733
-5.1%
|
17.04
|
US$12,490
|
|
|
2017-03-22 |
2017-03-21 |
S
Sale
|
Chief Executive Officer
Executive Director
|
2,807
-1.7%
17.03
US$47,803
|
2,807
-1.7%
|
17.03
|
US$47,803
|
|
|
2017-03-22 |
2017-03-21 |
S
Sale
|
DAWSON WILLIAM J
Chief Financial Officer
Officer
|
716
-4.8%
17.02
US$12,186
|
716
-4.8%
|
17.02
|
US$12,186
|
|
|
2016-09-16 |
2016-09-16 |
B
Purchase
|
MDV IX LP
Large shareholder
|
8,240
+0.2%
16.81
US$138,497
|
8,240
+0.2%
|
16.81
|
US$138,497
|
|
|
2016-09-16 |
2016-09-16 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
8,240
+0.2%
16.81
US$138,497
|
8,240
+0.2%
|
16.81
|
US$138,497
|
|
|
2016-09-16 |
2016-09-15 |
B
Purchase
|
MDV IX LP
Large shareholder
|
200
+0.0%
16.50
US$3,300
|
200
+0.0%
|
16.50
|
US$3,300
|
|
|
2016-09-16 |
2016-09-15 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
200
+0.0%
16.50
US$3,300
|
200
+0.0%
|
16.50
|
US$3,300
|
|
|
2016-09-16 |
2016-09-14 |
B
Purchase
|
MDV IX LP
Large shareholder
|
54,537
+1.4%
16.43
US$895,787
|
54,537
+1.4%
|
16.43
|
US$895,787
|
|
|
2016-09-16 |
2016-09-14 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
54,537
+1.4%
16.43
US$895,787
|
54,537
+1.4%
|
16.43
|
US$895,787
|
|
|
2016-09-14 |
2016-09-13 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
62,034
+1.6%
15.56
US$964,995
|
62,034
+1.6%
|
15.56
|
US$964,995
|
|
|
2016-09-14 |
2016-09-13 |
B
Purchase
|
MDV IX LP
Large shareholder
|
62,034
+1.6%
15.56
US$964,995
|
62,034
+1.6%
|
15.56
|
US$964,995
|
|
|
2016-09-14 |
2016-09-12 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
22,342
+0.6%
15.65
US$349,735
|
22,342
+0.6%
|
15.65
|
US$349,735
|
|
|
2016-09-14 |
2016-09-12 |
B
Purchase
|
MDV IX LP
Large shareholder
|
22,342
+0.6%
15.65
US$349,735
|
22,342
+0.6%
|
15.65
|
US$349,735
|
|
|
2016-09-09 |
2016-09-07 |
B
Purchase
|
MDV IX LP
Large shareholder
|
60,846
+1.6%
15.68
US$954,065
|
60,846
+1.6%
|
15.68
|
US$954,065
|
|
|
2016-09-09 |
2016-09-07 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
60,846
+1.6%
15.68
US$954,065
|
60,846
+1.6%
|
15.68
|
US$954,065
|
|
|
2016-09-07 |
2016-09-06 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
7,200
+0.2%
15.00
US$107,980
|
7,200
+0.2%
|
15.00
|
US$107,980
|
|
|
2016-09-07 |
2016-09-06 |
B
Purchase
|
MDV IX LP
Large shareholder
|
7,200
+0.2%
15.00
US$107,980
|
7,200
+0.2%
|
15.00
|
US$107,980
|
|
|
2016-09-07 |
2016-09-02 |
B
Purchase
|
Ericson William W.
Non-Executive Director
Large shareholder
|
43,719
+1.2%
14.75
US$644,921
|
43,719
+1.2%
|
14.75
|
US$644,921
|
|
|
2016-09-07 |
2016-09-02 |
B
Purchase
|
MDV IX LP
Large shareholder
|
43,719
+1.2%
14.75
US$644,921
|
43,719
+1.2%
|
14.75
|
US$644,921
|
|
|
2016-04-20 |
2016-04-18 |
PlS
Planned sale
|
McClure Natalie
SVP, Product Development
Officer
|
23,334
-73.7%
18.50
US$431,679
|
23,334
-73.7%
|
18.50
|
US$431,679
|
|
|
2016-04-20 |
2016-04-18 |
PlS
Planned sale
|
McClure Natalie
SVP, Product Development
Officer
|
12,666
-60.3%
18.50
US$234,321
|
12,666
-60.3%
|
18.50
|
US$234,321
|
|
|
2015-07-09 |
2015-07-08 |
PlS
Planned sale
|
MDV IX LP
Large shareholder
|
3,100
-1.0%
27.55
US$85,408
|
3,100
-1.0%
|
27.55
|
US$85,408
|
|
|
2015-07-09 |
2015-07-08 |
PlS
Planned sale
|
Ericson William W.
Non-Executive Director
Large shareholder
|
3,100
-1.0%
27.55
US$85,408
|
3,100
-1.0%
|
27.55
|
US$85,408
|
|
|
2015-06-09 |
2015-06-05 |
PlS
Planned sale
|
McClure Natalie
SVP, Product Development
Officer
|
2,000
-70.4%
18.95
US$37,900
|
2,000
-70.4%
|
18.95
|
US$37,900
|
|
|
2015-06-01 |
2015-05-29 |
PlS
Planned sale
|
Ericson William W.
Non-Executive Director
Large shareholder
|
112,073
-24.7%
18.02
US$2,019,555
|
112,073
-24.7%
|
18.02
|
US$2,019,555
|
|
|
2015-06-01 |
2015-05-29 |
PlS
Planned sale
|
MDV IX LP
Large shareholder
|
112,073
-24.7%
18.02
US$2,019,555
|
112,073
-24.7%
|
18.02
|
US$2,019,555
|
|
|
2015-05-14 |
2015-05-14 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
200
-0.1%
18.00
US$3,600
|
200
-0.1%
|
18.00
|
US$3,600
|
|
|
2015-05-14 |
2015-05-14 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
100
-0.3%
18.00
US$1,800
|
100
-0.3%
|
18.00
|
US$1,800
|
|
|
2015-05-14 |
2015-05-13 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
100
-0.0%
18.00
US$1,800
|
100
-0.0%
|
18.00
|
US$1,800
|
|
|
2015-05-14 |
2015-05-13 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
28
-0.1%
18.00
US$504
|
28
-0.1%
|
18.00
|
US$504
|
|
|
2015-05-14 |
2015-05-12 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
1,800
-0.5%
18.00
US$32,400
|
1,800
-0.5%
|
18.00
|
US$32,400
|
|
|
2015-05-14 |
2015-05-12 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
500
-2.4%
18.01
US$9,003
|
500
-2.4%
|
18.01
|
US$9,003
|
|
|
2015-05-07 |
2015-05-05 |
PlS
Planned sale
|
McClure Natalie
SVP, Product Development
Officer
|
2,000
-70.4%
17.62
US$35,240
|
2,000
-70.4%
|
17.62
|
US$35,240
|
|
|
2015-04-27 |
2015-04-23 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
2,400
-0.6%
18.01
US$43,212
|
2,400
-0.6%
|
18.01
|
US$43,212
|
|
|
2015-04-27 |
2015-04-23 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
900
-4.3%
18.00
US$16,200
|
900
-4.3%
|
18.00
|
US$16,200
|
|
|
2015-04-22 |
2015-04-21 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
1,811
-0.5%
18.00
US$32,602
|
1,811
-0.5%
|
18.00
|
US$32,602
|
|
|
2015-04-22 |
2015-04-21 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
962
-4.6%
18.01
US$17,322
|
962
-4.6%
|
18.01
|
US$17,322
|
|
|
2015-04-22 |
2015-04-20 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
5,200
-1.3%
18.00
US$93,601
|
5,200
-1.3%
|
18.00
|
US$93,601
|
|
|
2015-04-22 |
2015-04-20 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
2,610
-11.5%
18.00
US$46,981
|
2,610
-11.5%
|
18.00
|
US$46,981
|
|
|
2015-04-14 |
2015-04-14 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
100
-0.0%
18.00
US$1,800
|
100
-0.0%
|
18.00
|
US$1,800
|
|
|
2015-04-14 |
2015-04-14 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
80
-0.8%
18.00
US$1,440
|
80
-0.8%
|
18.00
|
US$1,440
|
|
|
2015-04-14 |
2015-04-10 |
PlS
Planned sale
|
Went Gregory T
Chief Executive Officer
Executive Director
Large shareholder
|
500
-0.1%
19.07
US$9,535
|
500
-0.1%
|
19.07
|
US$9,535
|
|