Rubin Marc

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2019-02-25	2019-02-22	Galectin Therapeutics Inc (GALT)	PlS Planned sale	18,640 -4.5% 317.58 US$3,640,093	18,640 -4.5%	317.58	US$3,640,093
2019-02-25	2019-02-21	Galectin Therapeutics Inc (GALT)	PlS Planned sale	38,165 -33.4% 83.03 US$760,843	38,165 -33.4%	83.03	US$760,843
2019-02-25	2019-02-21	Galectin Therapeutics Inc (GALT)	PlS Planned sale	11,630 +27.5% 340.29 US$3,027,228	11,630 +27.5%	340.29	US$3,027,228
2019-01-25	2019-01-23	Curis Inc (CRIS)	PlS Planned sale	18,500 -39.1% 1.05 US$19,477	18,500 -39.1%	1.05	US$19,477