RUDNICK SETH

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2020-12-29	2020-12-24	G1 Therapeutics Inc (GTHX)	PlS Planned sale	82,649 -33.3% 414.62 US$3,426,735	82,649 -33.3%	414.62	US$3,426,735
2020-12-23	2020-12-23	G1 Therapeutics Inc (GTHX)	PlS Planned sale	22,958 +38.1% 423.26 US$3,633,286	22,958 +38.1%	423.26	US$3,633,286
2020-12-23	2020-12-22	G1 Therapeutics Inc (GTHX)	PlS Planned sale	73,374 +28.4% 330.50 US$1,413,506	73,374 +28.4%	330.50	US$1,413,506
2020-12-10	2020-12-10	G1 Therapeutics Inc (GTHX)	PlS Planned sale	546 -1.4% 20.00 US$10,921	546 -1.4%	20.00	US$10,921
2020-12-10	2020-12-09	G1 Therapeutics Inc (GTHX)	PlS Planned sale	5,773 -12.9% 20.32 US$117,284	5,773 -12.9%	20.32	US$117,284
2020-12-10	2020-12-08	G1 Therapeutics Inc (GTHX)	PlS Planned sale	13,161 -22.8% 20.19 US$265,694	13,161 -22.8%	20.19	US$265,694
2020-12-03	2020-12-01	G1 Therapeutics Inc (GTHX)	PlS Planned sale	520 -0.9% 20.09 US$10,449	520 -0.9%	20.09	US$10,449