venBio Global Strategic Fund, L.P.

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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2021-10-26	2021-10-25	Metacrine, Inc. (MTCR)	S Sale	38,854 -10.7% 127.85 US$1,927,557	38,854 -10.7%	127.85	US$1,927,557
2021-10-26	2021-10-22	Metacrine, Inc. (MTCR)	S Sale	56,145 -32.8% 60.90 US$901,597	56,145 -32.8%	60.90	US$901,597
2020-09-22	2020-09-18	Metacrine, Inc. (MTCR)	B Purchase	62,521 +27.1% 309.34 US$1,610,933	62,521 +27.1%	309.34	US$1,610,933
2019-04-01	2019-04-01	Precision BioSciences Inc (DTIL)	B Purchase	50,000 +inf% 16.00 US$800,000	50,000 +inf%	16.00	US$800,000