James Cassella

Currently holds a position at Concert Pharmaceuticals Inc

Position	Company	Period
Chief Development Officer	Concert Pharmaceuticals Inc	Feb. 1, 2015 -

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2023-02-16	2023-02-15	Concert Pharmaceuticals Inc (CNCE)	PlS Planned sale	83,909 -35.0% 180.22 US$782,052	83,909 -35.0%	180.22	US$782,052
2023-01-31	2023-01-30	Concert Pharmaceuticals Inc (CNCE)	PlS Planned sale	75,100 -17.9% 205.46 US$3,888,862	75,100 -17.9%	205.46	US$3,888,862
2023-01-09	2023-01-06	Concert Pharmaceuticals Inc (CNCE)	PlS Planned sale	76,521 -17.5% 134.59 US$1,281,754	76,521 -17.5%	134.59	US$1,281,754
2022-02-16	2022-02-14	Concert Pharmaceuticals Inc (CNCE)	PlS Planned sale	3,762 -1.9% 3.09 US$11,625	3,762 -1.9%	3.09	US$11,625
2022-01-07	2022-01-05	Concert Pharmaceuticals Inc (CNCE)	PlS Planned sale	2,894 -3.4% 3.19 US$9,232	2,894 -3.4%	3.19	US$9,232
2021-02-17	2021-02-16	Concert Pharmaceuticals Inc (CNCE)	PlS Planned sale	3,763 -3.8% 7.32 US$27,545	3,763 -3.8%	7.32	US$27,545
2020-08-19	2020-08-17	Concert Pharmaceuticals Inc (CNCE)	PlS Planned sale	4,354 -5.4% 10.37 US$45,151	4,354 -5.4%	10.37	US$45,151