United States Biotechnology & Medical Research

Shire Viropharma Inc (VPHM)

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Ticker: VPHM Exchange: NSQ
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
Broom Colin MD
VP & Chief Scientific Officer
1 sale — total 394,301 USD
Planned sale 24 Dec 2012
Value US$1,167,020.01 | Price 107.42 | Shares 17,173
Sale 13 Dec 2012
Value US$4,409,792.15 | Price 40.82 | Shares 83,706
Planned sale 10 Dec 2012
Value US$360,983.93 | Price 24.07 | Shares 14,999
Sale 10 Dec 2012
Value US$1,203,360.00 | Price 24.07 | Shares 50,000
Sale 10 Dec 2012
Value US$240,672.00 | Price 24.07 | Shares 10,000
Sale 3 Dec 2012
Value US$447,256.80 | Price 24.85 | Shares 18,000
Buy 3 Dec 2012
Value US$62,675.00 | Price 25.07 | Shares 2,500
Sale 3 Dec 2012
Value US$248,000.00 | Price 24.80 | Shares 10,000
Sale 30 Nov 2012
Value US$247,795.00 | Price 24.78 | Shares 10,000
Sale 30 Nov 2012
Value US$495,590.00 | Price 24.78 | Shares 20,000
Sale 28 Nov 2012
Value US$363,325.50 | Price 24.22 | Shares 15,000
Sale 28 Nov 2012
Value US$60,554.25 | Price 24.22 | Shares 2,500
Sale 13 Nov 2012
Value US$312,585.00 | Price 25.01 | Shares 12,500
Sale 13 Nov 2012
Value US$248,426.00 | Price 24.84 | Shares 10,000
Sale 8 Nov 2012
Value US$1,016,521.97 | Price 24.54 | Shares 41,418
Sale 8 Nov 2012
Value US$1,030,806.00 | Price 24.54 | Shares 42,000
Sale 2 Nov 2012
Value US$253,703.00 | Price 25.37 | Shares 10,000
Sale 11 Jun 2012
Value US$200,430.00 | Price 20.04 | Shares 10,000
Planned sale 23 Mar 2012
Value US$600,000.00 | Price 30.00 | Shares 20,000
Sale 9 Mar 2012
Value US$38,618.06 | Price 29.71 | Shares 1,300
Sale 9 Mar 2012
Value US$948,953.60 | Price 29.65 | Shares 32,000
Sale 5 Mar 2012
Value US$174,953.00 | Price 33.01 | Shares 5,300
Sale 5 Mar 2012
Value US$6,820,212.00 | Price 32.48 | Shares 210,000
Sale 1 Mar 2012
Value US$989,700.00 | Price 32.99 | Shares 30,000
Sale 1 Mar 2012
Value US$409,434.38 | Price 32.11 | Shares 12,750
Sale 1 Mar 2012
Value US$2,248,197.00 | Price 32.12 | Shares 70,000
Buy 14 Dec 2011
Value US$1,379,860.18 | Price 27.29 | Shares 50,566
Buy 14 Dec 2011
Value US$7,960,160.84 | Price 27.29 | Shares 291,706
Buy 14 Dec 2011
Value US$213,612.81 | Price 27.29 | Shares 7,828
Planned sale 14 Dec 2011
Value US$629,250.00 | Price 25.17 | Shares 25,000
Planned sale 14 Dec 2011
Value US$637,500.00 | Price 25.50 | Shares 25,000
Planned sale 13 Dec 2011
Value US$524,755.00 | Price 23.50 | Shares 22,330
Planned sale 12 Dec 2011
Value US$415,317.45 | Price 23.50 | Shares 17,670
Sale 1 Dec 2011
Value US$238,159.00 | Price 23.82 | Shares 10,000
Planned sale 30 Nov 2011
Value US$480,000.00 | Price 24.00 | Shares 20,000
Planned sale 28 Nov 2011
Value US$437,000.00 | Price 23.00 | Shares 19,000
Sale 28 Nov 2011
Value US$115,000.00 | Price 23.00 | Shares 5,000
Planned sale 23 Nov 2011
Value US$23,000.00 | Price 23.00 | Shares 1,000
Planned sale 21 Nov 2011
Value US$939,127.30 | Price 22.53 | Shares 41,691
Planned sale 21 Nov 2011
Value US$450,427.90 | Price 22.53 | Shares 19,996
Planned sale 21 Nov 2011
Value US$337,888.50 | Price 22.53 | Shares 15,000
Sale 16 Nov 2011
Value US$45,180.60 | Price 22.59 | Shares 2,000
Planned sale 14 Nov 2011
Value US$440,000.00 | Price 22.00 | Shares 20,000
Sale 7 Nov 2011
Value US$258,194.48 | Price 21.08 | Shares 12,250
Sale 7 Nov 2011
Value US$4,202.00 | Price 21.01 | Shares 200
Sale 7 Nov 2011
Value US$415,800.00 | Price 21.00 | Shares 19,800
Planned sale 1 Nov 2011
Value US$483,640.52 | Price 20.05 | Shares 24,121
Sale 31 Oct 2011
Value US$418,555.04 | Price 20.42 | Shares 20,495
Buy 5 Oct 2011
Value US$2,650,423.21 | Price 18.18 | Shares 145,763
Buy 5 Oct 2011
Value US$295,984.50 | Price 18.18 | Shares 16,278
Buy 5 Oct 2011
Value US$109,407.71 | Price 18.18 | Shares 6,017
Buy 4 Oct 2011
Value US$796,644.22 | Price 17.48 | Shares 45,584
Buy 4 Oct 2011
Value US$43,883.24 | Price 17.48 | Shares 2,511
Buy 4 Oct 2011
Value US$33,292.54 | Price 17.48 | Shares 1,905
Buy 3 Oct 2011
Value US$7,890,268.95 | Price 17.71 | Shares 445,574
Buy 3 Oct 2011
Value US$1,244,588.92 | Price 17.62 | Shares 70,629
Buy 30 Sep 2011
Value US$1,602,891.96 | Price 18.08 | Shares 88,657
Buy 30 Sep 2011
Value US$788,121.62 | Price 18.19 | Shares 43,321
Buy 30 Sep 2011
Value US$245,450.01 | Price 18.08 | Shares 13,576
Buy 30 Sep 2011
Value US$120,689.71 | Price 18.19 | Shares 6,634
Buy 30 Sep 2011
Value US$60,874.35 | Price 18.08 | Shares 3,367
Buy 30 Sep 2011
Value US$29,926.83 | Price 18.19 | Shares 1,645
Buy 29 Sep 2011
Value US$2,878,882.04 | Price 18.00 | Shares 159,945
Buy 29 Sep 2011
Value US$1,616,392.02 | Price 17.97 | Shares 89,970
Buy 29 Sep 2011
Value US$380,089.11 | Price 18.00 | Shares 21,117
Buy 29 Sep 2011
Value US$213,398.96 | Price 17.97 | Shares 11,878
Buy 29 Sep 2011
Value US$109,507.13 | Price 18.00 | Shares 6,084
Buy 29 Sep 2011
Value US$61,497.28 | Price 17.97 | Shares 3,423
Buy 26 Sep 2011
Value US$85,155.20 | Price 18.13 | Shares 4,697
Buy 26 Sep 2011
Value US$400,294.58 | Price 18.13 | Shares 22,084
Buy 26 Sep 2011
Value US$19,997.06 | Price 18.13 | Shares 1,103
Buy 26 Sep 2011
Value US$93,965.18 | Price 18.13 | Shares 5,184
Buy 26 Sep 2011
Value US$507,631.60 | Price 18.13 | Shares 28,000
Buy 26 Sep 2011
Value US$2,386,124.77 | Price 18.13 | Shares 131,641
Buy 23 Sep 2011
Value US$156,988.32 | Price 17.78 | Shares 8,828
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2012-12-27 2012-12-24 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
17,173 +36.3%
107.42
US$1,167,020 		17,173 +36.3% 107.42 US$1,167,020
2012-12-17 2012-12-13 S Sale BROOKE PAUL A Non-Executive Director
83,706 +48.4%
40.82
US$4,409,792 		83,706 +48.4% 40.82 US$4,409,792
2012-12-12 2012-12-10 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
56,638 -12.4%
368.19
US$3,170,795 		56,638 -12.4% 368.19 US$3,170,795
2012-12-12 2012-12-10 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
50,000 -57.0%
24.07
US$1,203,360 		50,000 -57.0% 24.07 US$1,203,360
2012-12-12 2012-12-10 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
10,000 -21.0%
24.07
US$240,672 		10,000 -21.0% 24.07 US$240,672
2012-12-05 2012-12-03 S Sale Wolf John Peter III

VP, General Counsel

Officer
18,000 -100.0%
24.85
US$447,257 		18,000 -100.0% 24.85 US$447,257
2012-12-05 2012-12-03 B Purchase DOUGHERTY MICHAEL R Non-Executive Director
2,500 +55.6%
25.07
US$62,675 		2,500 +55.6% 25.07 US$62,675
2012-12-05 2012-12-03 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -18.3%
24.80
US$248,000 		10,000 -18.3% 24.80 US$248,000
2012-12-04 2012-11-30 S Sale GLASER ROBERT Non-Executive Director
10,000 -19.5%
24.78
US$247,795 		10,000 -19.5% 24.78 US$247,795
2012-12-04 2012-11-30 S Sale GLASER ROBERT Non-Executive Director
20,000 -32.6%
24.78
US$495,590 		20,000 -32.6% 24.78 US$495,590
2012-11-30 2012-11-28 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
15,000 -21.6%
24.22
US$363,326 		15,000 -21.6% 24.22 US$363,326
2012-11-30 2012-11-28 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
2,500 -4.4%
24.22
US$60,554 		2,500 -4.4% 24.22 US$60,554
2012-11-15 2012-11-13 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
12,500 -18.7%
25.01
US$312,585 		12,500 -18.7% 25.01 US$312,585
2012-11-15 2012-11-13 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -15.5%
24.84
US$248,426 		10,000 -15.5% 24.84 US$248,426
2012-11-13 2012-11-08 S Sale MILANO VINCENT

President and CEO

Executive Director
41,418 -30.5%
24.54
US$1,016,522 		41,418 -30.5% 24.54 US$1,016,522
2012-11-13 2012-11-08 S Sale MILANO VINCENT

President and CEO

Executive Director
42,000 -30.8%
24.54
US$1,030,806 		42,000 -30.8% 24.54 US$1,030,806
2012-11-05 2012-11-02 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -15.5%
25.37
US$253,703 		10,000 -15.5% 25.37 US$253,703
2012-06-13 2012-06-11 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -13.4%
20.04
US$200,430 		10,000 -13.4% 20.04 US$200,430
2012-03-27 2012-03-23 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
20,000 -82.9%
30.00
US$600,000 		20,000 -82.9% 30.00 US$600,000
2012-03-12 2012-03-09 S Sale Morris Richard Steven

Chief Accounting Officer

Officer
1,300 -51.1%
29.71
US$38,618 		1,300 -51.1% 29.71 US$38,618
2012-03-12 2012-03-09 S Sale Fletcher Robert C.

V.P., Business Development

Officer
32,000 -99.3%
29.65
US$948,954 		32,000 -99.3% 29.65 US$948,954
2012-03-07 2012-03-05 S Sale Morris Richard Steven

Chief Accounting Officer

Officer
5,300 -81.0%
33.01
US$174,953 		5,300 -81.0% 33.01 US$174,953
2012-03-07 2012-03-05 S Sale DOYLE THOMAS F

VP Strategic Initiatives

Officer
210,000 -80.0%
32.48
US$6,820,212 		210,000 -80.0% 32.48 US$6,820,212
2012-03-06 2012-03-01 S Sale SOLAND DANIEL B

VP, Chief Operating Officer

Officer
30,000 -41.2%
32.99
US$989,700 		30,000 -41.2% 32.99 US$989,700
2012-03-05 2012-03-01 S Sale Rowland Charles A Jr

VP, Chief Financial Officer

Officer
12,750 -42.7%
32.11
US$409,434 		12,750 -42.7% 32.11 US$409,434
2012-03-05 2012-03-01 S Sale Rowland Charles A Jr

VP, Chief Financial Officer

Officer
70,000 -70.1%
32.12
US$2,248,197 		70,000 -70.1% 32.12 US$2,248,197
2011-12-16 2011-12-14 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
50,566 +2.6%
27.29
US$1,379,860 		50,566 +2.6% 27.29 US$1,379,860
2011-12-16 2011-12-14 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
291,706 +3.1%
27.29
US$7,960,161 		291,706 +3.1% 27.29 US$7,960,161
2011-12-16 2011-12-14 B Purchase 14159 capital (GP), LLC Large shareholder
7,828 +2.6%
27.29
US$213,613 		7,828 +2.6% 27.29 US$213,613
2011-12-15 2011-12-14 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
25,000 -56.3%
25.17
US$629,250 		25,000 -56.3% 25.17 US$629,250
2011-12-15 2011-12-14 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
25,000 -56.3%
25.50
US$637,500 		25,000 -56.3% 25.50 US$637,500
2011-12-14 2011-12-13 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
22,330 -53.5%
23.50
US$524,755 		22,330 -53.5% 23.50 US$524,755
2011-12-14 2011-12-12 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
17,670 -47.6%
23.50
US$415,317 		17,670 -47.6% 23.50 US$415,317
2011-12-05 2011-12-01 S Sale DOYLE THOMAS F

VP Strategic Initiatives

Officer
10,000 -16.0%
23.82
US$238,159 		10,000 -16.0% 23.82 US$238,159
2011-12-01 2011-11-30 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
20,000 -83.6%
24.00
US$480,000 		20,000 -83.6% 24.00 US$480,000
2011-11-29 2011-11-28 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
19,000 -82.9%
23.00
US$437,000 		19,000 -82.9% 23.00 US$437,000
2011-11-29 2011-11-28 S Sale GLASER ROBERT Non-Executive Director
5,000 -11.9%
23.00
US$115,000 		5,000 -11.9% 23.00 US$115,000
2011-11-28 2011-11-23 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
1,000 -25.6%
23.00
US$23,000 		1,000 -25.6% 23.00 US$23,000
2011-11-23 2011-11-21 PlS Planned sale MILANO VINCENT

President and CEO

Executive Director
41,691 -35.4%
22.53
US$939,127 		41,691 -35.4% 22.53 US$939,127
2011-11-23 2011-11-21 PlS Planned sale MILANO VINCENT

President and CEO

Executive Director
19,996 -20.8%
22.53
US$450,428 		19,996 -20.8% 22.53 US$450,428
2011-11-23 2011-11-21 PlS Planned sale MILANO VINCENT

President and CEO

Executive Director
15,000 -16.4%
22.53
US$337,888 		15,000 -16.4% 22.53 US$337,888
2011-11-17 2011-11-16 S Sale Morris Richard Steven

Chief Accounting Officer

Officer
2,000 -63.2%
22.59
US$45,181 		2,000 -63.2% 22.59 US$45,181
2011-11-15 2011-11-14 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
20,000 -83.6%
22.00
US$440,000 		20,000 -83.6% 22.00 US$440,000
2011-11-09 2011-11-07 S Sale Wolf John Peter III

VP, General Counsel

Officer
12,250 -100.0%
21.08
US$258,194 		12,250 -100.0% 21.08 US$258,194
2011-11-08 2011-11-07 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
200 -1.0%
21.01
US$4,202 		200 -1.0% 21.01 US$4,202
2011-11-08 2011-11-07 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
19,800 -50.2%
21.00
US$415,800 		19,800 -50.2% 21.00 US$415,800
2011-11-02 2011-11-01 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
24,121 -55.4%
20.05
US$483,641 		24,121 -55.4% 20.05 US$483,641
2011-11-02 2011-10-31 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
20,495 -51.3%
20.42
US$418,555 		20,495 -51.3% 20.42 US$418,555
2011-10-06 2011-10-05 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
145,763 +1.6%
18.18
US$2,650,423 		145,763 +1.6% 18.18 US$2,650,423
2011-10-06 2011-10-05 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
16,278 +0.9%
18.18
US$295,985 		16,278 +0.9% 18.18 US$295,985
2011-10-06 2011-10-05 B Purchase 14159 capital (GP), LLC Large shareholder
6,017 +2.1%
18.18
US$109,408 		6,017 +2.1% 18.18 US$109,408
2011-10-06 2011-10-04 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
45,584 +0.5%
17.48
US$796,644 		45,584 +0.5% 17.48 US$796,644
2011-10-06 2011-10-04 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
2,511 +0.1%
17.48
US$43,883 		2,511 +0.1% 17.48 US$43,883
2011-10-06 2011-10-04 B Purchase 14159 capital (GP), LLC Large shareholder
1,905 +0.7%
17.48
US$33,293 		1,905 +0.7% 17.48 US$33,293
2011-10-03 2011-10-03 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
445,574 +5.0%
17.71
US$7,890,269 		445,574 +5.0% 17.71 US$7,890,269
2011-10-03 2011-10-03 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
70,629 +0.8%
17.62
US$1,244,589 		70,629 +0.8% 17.62 US$1,244,589
2011-10-03 2011-09-30 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
88,657 +1.0%
18.08
US$1,602,892 		88,657 +1.0% 18.08 US$1,602,892
2011-10-03 2011-09-30 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
43,321 +0.5%
18.19
US$788,122 		43,321 +0.5% 18.19 US$788,122
2011-10-03 2011-09-30 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
13,576 +0.7%
18.08
US$245,450 		13,576 +0.7% 18.08 US$245,450
2011-10-03 2011-09-30 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
6,634 +0.4%
18.19
US$120,690 		6,634 +0.4% 18.19 US$120,690
2011-10-03 2011-09-30 B Purchase 14159 capital (GP), LLC Large shareholder
3,367 +1.2%
18.08
US$60,874 		3,367 +1.2% 18.08 US$60,874
2011-10-03 2011-09-30 B Purchase 14159 capital (GP), LLC Large shareholder
1,645 +0.6%
18.19
US$29,927 		1,645 +0.6% 18.19 US$29,927
2011-10-03 2011-09-29 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
159,945 +1.9%
18.00
US$2,878,882 		159,945 +1.9% 18.00 US$2,878,882
2011-10-03 2011-09-29 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
21,117 +1.1%
18.00
US$380,089 		21,117 +1.1% 18.00 US$380,089
2011-10-03 2011-09-29 B Purchase 14159 capital (GP), LLC Large shareholder
6,084 +2.2%
18.00
US$109,507 		6,084 +2.2% 18.00 US$109,507
2011-10-03 2011-09-29 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
89,970 +1.1%
17.97
US$1,616,392 		89,970 +1.1% 17.97 US$1,616,392
2011-10-03 2011-09-29 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
11,878 +0.6%
17.97
US$213,399 		11,878 +0.6% 17.97 US$213,399
2011-10-03 2011-09-29 B Purchase 14159 capital (GP), LLC Large shareholder
3,423 +1.3%
17.97
US$61,497 		3,423 +1.3% 17.97 US$61,497
2011-09-26 2011-09-26 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
4,697 +0.3%
18.13
US$85,155 		4,697 +0.3% 18.13 US$85,155
2011-09-26 2011-09-26 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
22,084 +1.2%
18.13
US$400,295 		22,084 +1.2% 18.13 US$400,295
2011-09-26 2011-09-26 B Purchase 14159 capital (GP), LLC Large shareholder
1,103 +0.4%
18.13
US$19,997 		1,103 +0.4% 18.13 US$19,997
2011-09-26 2011-09-26 B Purchase 14159 capital (GP), LLC Large shareholder
5,184 +1.9%
18.13
US$93,965 		5,184 +1.9% 18.13 US$93,965
2011-09-26 2011-09-26 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
28,000 +0.3%
18.13
US$507,632 		28,000 +0.3% 18.13 US$507,632
2011-09-26 2011-09-26 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
131,641 +1.6%
18.13
US$2,386,125 		131,641 +1.6% 18.13 US$2,386,125
2011-09-26 2011-09-23 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
8,828 +0.5%
17.78
US$156,988 		8,828 +0.5% 17.78 US$156,988
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