United States Biotechnology & Medical Research

Shire Viropharma Inc (VPHM)

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Ticker: VPHM Exchange: NSQ
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
No insider activity signals detected

Insider trades have not triggered unusual activity signals for this company.

Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Planned sale
Price
107.42
Quantity 17,173 +36.3%
Value US$1,167,020
BROOKE PAUL A Non-Executive Director
Transaction date
Sale
Price
40.82
Quantity 83,706 +48.4%
Value US$4,409,792
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Planned sale
Price
368.19
Quantity 56,638 -12.4%
Value US$3,170,795
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Sale
Price
24.07
Quantity 50,000 -57.0%
Value US$1,203,360
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Sale
Price
24.07
Quantity 10,000 -21.0%
Value US$240,672
Wolf John Peter III VP, General Counsel Officer
Transaction date
Sale
Price
24.85
Quantity 18,000 -100.0%
Value US$447,257
DOUGHERTY MICHAEL R Non-Executive Director
Transaction date
Purchase
Price
25.07
Quantity 2,500 +55.6%
Value US$62,675
CLAYPOOL WILLIAM D MD Non-Executive Director
Transaction date
Sale
Price
24.80
Quantity 10,000 -18.3%
Value US$248,000
GLASER ROBERT Non-Executive Director
Transaction date
Sale
Price
24.78
Quantity 10,000 -19.5%
Value US$247,795
GLASER ROBERT Non-Executive Director
Transaction date
Sale
Price
24.78
Quantity 20,000 -32.6%
Value US$495,590
CLAYPOOL WILLIAM D MD Non-Executive Director
Transaction date
Sale
Price
24.22
Quantity 15,000 -21.6%
Value US$363,326
CLAYPOOL WILLIAM D MD Non-Executive Director
Transaction date
Sale
Price
24.22
Quantity 2,500 -4.4%
Value US$60,554
CLAYPOOL WILLIAM D MD Non-Executive Director
Transaction date
Sale
Price
25.01
Quantity 12,500 -18.7%
Value US$312,585
CLAYPOOL WILLIAM D MD Non-Executive Director
Transaction date
Sale
Price
24.84
Quantity 10,000 -15.5%
Value US$248,426
MILANO VINCENT President and CEO Executive Director
Transaction date
Sale
Price
24.54
Quantity 41,418 -30.5%
Value US$1,016,522
MILANO VINCENT President and CEO Executive Director
Transaction date
Sale
Price
24.54
Quantity 42,000 -30.8%
Value US$1,030,806
CLAYPOOL WILLIAM D MD Non-Executive Director
Transaction date
Sale
Price
25.37
Quantity 10,000 -15.5%
Value US$253,703
CLAYPOOL WILLIAM D MD Non-Executive Director
Transaction date
Sale
Price
20.04
Quantity 10,000 -13.4%
Value US$200,430
Pietrusko Robert VP, Regulatory & Quality Officer
Transaction date
Planned sale
Price
30.00
Quantity 20,000 -82.9%
Value US$600,000
Morris Richard Steven Chief Accounting Officer Officer
Transaction date
Sale
Price
29.71
Quantity 1,300 -51.1%
Value US$38,618
Fletcher Robert C. V.P., Business Development Officer
Transaction date
Sale
Price
29.65
Quantity 32,000 -99.3%
Value US$948,954
Morris Richard Steven Chief Accounting Officer Officer
Transaction date
Sale
Price
33.01
Quantity 5,300 -81.0%
Value US$174,953
DOYLE THOMAS F VP Strategic Initiatives Officer
Transaction date
Sale
Price
32.48
Quantity 210,000 -80.0%
Value US$6,820,212
SOLAND DANIEL B VP, Chief Operating Officer Officer
Transaction date
Sale
Price
32.99
Quantity 30,000 -41.2%
Value US$989,700
Rowland Charles A Jr VP, Chief Financial Officer Officer
Transaction date
Sale
Price
32.11
Quantity 12,750 -42.7%
Value US$409,434
Rowland Charles A Jr VP, Chief Financial Officer Officer
Transaction date
Sale
Price
32.12
Quantity 70,000 -70.1%
Value US$2,248,197
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
27.29
Quantity 50,566 +2.6%
Value US$1,379,860
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
27.29
Quantity 291,706 +3.1%
Value US$7,960,161
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
27.29
Quantity 7,828 +2.6%
Value US$213,613
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Planned sale
Price
25.17
Quantity 25,000 -56.3%
Value US$629,250
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Planned sale
Price
25.50
Quantity 25,000 -56.3%
Value US$637,500
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Planned sale
Price
23.50
Quantity 22,330 -53.5%
Value US$524,755
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Planned sale
Price
23.50
Quantity 17,670 -47.6%
Value US$415,317
DOYLE THOMAS F VP Strategic Initiatives Officer
Transaction date
Sale
Price
23.82
Quantity 10,000 -16.0%
Value US$238,159
Pietrusko Robert VP, Regulatory & Quality Officer
Transaction date
Planned sale
Price
24.00
Quantity 20,000 -83.6%
Value US$480,000
Pietrusko Robert VP, Regulatory & Quality Officer
Transaction date
Planned sale
Price
23.00
Quantity 19,000 -82.9%
Value US$437,000
GLASER ROBERT Non-Executive Director
Transaction date
Sale
Price
23.00
Quantity 5,000 -11.9%
Value US$115,000
Pietrusko Robert VP, Regulatory & Quality Officer
Transaction date
Planned sale
Price
23.00
Quantity 1,000 -25.6%
Value US$23,000
MILANO VINCENT President and CEO Executive Director
Transaction date
Planned sale
Price
22.53
Quantity 41,691 -35.4%
Value US$939,127
MILANO VINCENT President and CEO Executive Director
Transaction date
Planned sale
Price
22.53
Quantity 19,996 -20.8%
Value US$450,428
MILANO VINCENT President and CEO Executive Director
Transaction date
Planned sale
Price
22.53
Quantity 15,000 -16.4%
Value US$337,888
Morris Richard Steven Chief Accounting Officer Officer
Transaction date
Sale
Price
22.59
Quantity 2,000 -63.2%
Value US$45,181
Pietrusko Robert VP, Regulatory & Quality Officer
Transaction date
Planned sale
Price
22.00
Quantity 20,000 -83.6%
Value US$440,000
Wolf John Peter III VP, General Counsel Officer
Transaction date
Sale
Price
21.08
Quantity 12,250 -100.0%
Value US$258,194
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Sale
Price
21.01
Quantity 200 -1.0%
Value US$4,202
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Sale
Price
21.00
Quantity 19,800 -50.2%
Value US$415,800
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Planned sale
Price
20.05
Quantity 24,121 -55.4%
Value US$483,641
Broom Colin MD VP & Chief Scientific Officer Officer
Transaction date
Sale
Price
20.42
Quantity 20,495 -51.3%
Value US$418,555
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.18
Quantity 145,763 +1.6%
Value US$2,650,423
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.18
Quantity 16,278 +0.9%
Value US$295,985
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.18
Quantity 6,017 +2.1%
Value US$109,408
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.48
Quantity 45,584 +0.5%
Value US$796,644
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.48
Quantity 2,511 +0.1%
Value US$43,883
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.48
Quantity 1,905 +0.7%
Value US$33,293
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.71
Quantity 445,574 +5.0%
Value US$7,890,269
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.62
Quantity 70,629 +0.8%
Value US$1,244,589
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.08
Quantity 88,657 +1.0%
Value US$1,602,892
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.19
Quantity 43,321 +0.5%
Value US$788,122
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.08
Quantity 13,576 +0.7%
Value US$245,450
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.19
Quantity 6,634 +0.4%
Value US$120,690
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.08
Quantity 3,367 +1.2%
Value US$60,874
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.19
Quantity 1,645 +0.6%
Value US$29,927
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.00
Quantity 159,945 +1.9%
Value US$2,878,882
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.00
Quantity 21,117 +1.1%
Value US$380,089
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.00
Quantity 6,084 +2.2%
Value US$109,507
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.97
Quantity 89,970 +1.1%
Value US$1,616,392
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.97
Quantity 11,878 +0.6%
Value US$213,399
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.97
Quantity 3,423 +1.3%
Value US$61,497
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.13
Quantity 4,697 +0.3%
Value US$85,155
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.13
Quantity 22,084 +1.2%
Value US$400,295
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.13
Quantity 1,103 +0.4%
Value US$19,997
14159 capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.13
Quantity 5,184 +1.9%
Value US$93,965
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.13
Quantity 28,000 +0.3%
Value US$507,632
Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
18.13
Quantity 131,641 +1.6%
Value US$2,386,125
Baker Biotech Capital (GP), LLC Large shareholder
Transaction date
Purchase
Price
17.78
Quantity 8,828 +0.5%
Value US$156,988
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2012-12-27 2012-12-24 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
17,173 +36.3%
107.42
US$1,167,020 		17,173 +36.3% 107.42 US$1,167,020
2012-12-17 2012-12-13 S Sale BROOKE PAUL A Non-Executive Director
83,706 +48.4%
40.82
US$4,409,792 		83,706 +48.4% 40.82 US$4,409,792
2012-12-12 2012-12-10 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
56,638 -12.4%
368.19
US$3,170,795 		56,638 -12.4% 368.19 US$3,170,795
2012-12-12 2012-12-10 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
50,000 -57.0%
24.07
US$1,203,360 		50,000 -57.0% 24.07 US$1,203,360
2012-12-12 2012-12-10 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
10,000 -21.0%
24.07
US$240,672 		10,000 -21.0% 24.07 US$240,672
2012-12-05 2012-12-03 S Sale Wolf John Peter III

VP, General Counsel

Officer
18,000 -100.0%
24.85
US$447,257 		18,000 -100.0% 24.85 US$447,257
2012-12-05 2012-12-03 B Purchase DOUGHERTY MICHAEL R Non-Executive Director
2,500 +55.6%
25.07
US$62,675 		2,500 +55.6% 25.07 US$62,675
2012-12-05 2012-12-03 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -18.3%
24.80
US$248,000 		10,000 -18.3% 24.80 US$248,000
2012-12-04 2012-11-30 S Sale GLASER ROBERT Non-Executive Director
10,000 -19.5%
24.78
US$247,795 		10,000 -19.5% 24.78 US$247,795
2012-12-04 2012-11-30 S Sale GLASER ROBERT Non-Executive Director
20,000 -32.6%
24.78
US$495,590 		20,000 -32.6% 24.78 US$495,590
2012-11-30 2012-11-28 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
15,000 -21.6%
24.22
US$363,326 		15,000 -21.6% 24.22 US$363,326
2012-11-30 2012-11-28 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
2,500 -4.4%
24.22
US$60,554 		2,500 -4.4% 24.22 US$60,554
2012-11-15 2012-11-13 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
12,500 -18.7%
25.01
US$312,585 		12,500 -18.7% 25.01 US$312,585
2012-11-15 2012-11-13 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -15.5%
24.84
US$248,426 		10,000 -15.5% 24.84 US$248,426
2012-11-13 2012-11-08 S Sale MILANO VINCENT

President and CEO

Executive Director
41,418 -30.5%
24.54
US$1,016,522 		41,418 -30.5% 24.54 US$1,016,522
2012-11-13 2012-11-08 S Sale MILANO VINCENT

President and CEO

Executive Director
42,000 -30.8%
24.54
US$1,030,806 		42,000 -30.8% 24.54 US$1,030,806
2012-11-05 2012-11-02 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -15.5%
25.37
US$253,703 		10,000 -15.5% 25.37 US$253,703
2012-06-13 2012-06-11 S Sale CLAYPOOL WILLIAM D MD Non-Executive Director
10,000 -13.4%
20.04
US$200,430 		10,000 -13.4% 20.04 US$200,430
2012-03-27 2012-03-23 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
20,000 -82.9%
30.00
US$600,000 		20,000 -82.9% 30.00 US$600,000
2012-03-12 2012-03-09 S Sale Morris Richard Steven

Chief Accounting Officer

Officer
1,300 -51.1%
29.71
US$38,618 		1,300 -51.1% 29.71 US$38,618
2012-03-12 2012-03-09 S Sale Fletcher Robert C.

V.P., Business Development

Officer
32,000 -99.3%
29.65
US$948,954 		32,000 -99.3% 29.65 US$948,954
2012-03-07 2012-03-05 S Sale Morris Richard Steven

Chief Accounting Officer

Officer
5,300 -81.0%
33.01
US$174,953 		5,300 -81.0% 33.01 US$174,953
2012-03-07 2012-03-05 S Sale DOYLE THOMAS F

VP Strategic Initiatives

Officer
210,000 -80.0%
32.48
US$6,820,212 		210,000 -80.0% 32.48 US$6,820,212
2012-03-06 2012-03-01 S Sale SOLAND DANIEL B

VP, Chief Operating Officer

Officer
30,000 -41.2%
32.99
US$989,700 		30,000 -41.2% 32.99 US$989,700
2012-03-05 2012-03-01 S Sale Rowland Charles A Jr

VP, Chief Financial Officer

Officer
12,750 -42.7%
32.11
US$409,434 		12,750 -42.7% 32.11 US$409,434
2012-03-05 2012-03-01 S Sale Rowland Charles A Jr

VP, Chief Financial Officer

Officer
70,000 -70.1%
32.12
US$2,248,197 		70,000 -70.1% 32.12 US$2,248,197
2011-12-16 2011-12-14 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
50,566 +2.6%
27.29
US$1,379,860 		50,566 +2.6% 27.29 US$1,379,860
2011-12-16 2011-12-14 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
291,706 +3.1%
27.29
US$7,960,161 		291,706 +3.1% 27.29 US$7,960,161
2011-12-16 2011-12-14 B Purchase 14159 capital (GP), LLC Large shareholder
7,828 +2.6%
27.29
US$213,613 		7,828 +2.6% 27.29 US$213,613
2011-12-15 2011-12-14 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
25,000 -56.3%
25.17
US$629,250 		25,000 -56.3% 25.17 US$629,250
2011-12-15 2011-12-14 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
25,000 -56.3%
25.50
US$637,500 		25,000 -56.3% 25.50 US$637,500
2011-12-14 2011-12-13 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
22,330 -53.5%
23.50
US$524,755 		22,330 -53.5% 23.50 US$524,755
2011-12-14 2011-12-12 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
17,670 -47.6%
23.50
US$415,317 		17,670 -47.6% 23.50 US$415,317
2011-12-05 2011-12-01 S Sale DOYLE THOMAS F

VP Strategic Initiatives

Officer
10,000 -16.0%
23.82
US$238,159 		10,000 -16.0% 23.82 US$238,159
2011-12-01 2011-11-30 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
20,000 -83.6%
24.00
US$480,000 		20,000 -83.6% 24.00 US$480,000
2011-11-29 2011-11-28 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
19,000 -82.9%
23.00
US$437,000 		19,000 -82.9% 23.00 US$437,000
2011-11-29 2011-11-28 S Sale GLASER ROBERT Non-Executive Director
5,000 -11.9%
23.00
US$115,000 		5,000 -11.9% 23.00 US$115,000
2011-11-28 2011-11-23 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
1,000 -25.6%
23.00
US$23,000 		1,000 -25.6% 23.00 US$23,000
2011-11-23 2011-11-21 PlS Planned sale MILANO VINCENT

President and CEO

Executive Director
41,691 -35.4%
22.53
US$939,127 		41,691 -35.4% 22.53 US$939,127
2011-11-23 2011-11-21 PlS Planned sale MILANO VINCENT

President and CEO

Executive Director
19,996 -20.8%
22.53
US$450,428 		19,996 -20.8% 22.53 US$450,428
2011-11-23 2011-11-21 PlS Planned sale MILANO VINCENT

President and CEO

Executive Director
15,000 -16.4%
22.53
US$337,888 		15,000 -16.4% 22.53 US$337,888
2011-11-17 2011-11-16 S Sale Morris Richard Steven

Chief Accounting Officer

Officer
2,000 -63.2%
22.59
US$45,181 		2,000 -63.2% 22.59 US$45,181
2011-11-15 2011-11-14 PlS Planned sale Pietrusko Robert

VP, Regulatory & Quality

Officer
20,000 -83.6%
22.00
US$440,000 		20,000 -83.6% 22.00 US$440,000
2011-11-09 2011-11-07 S Sale Wolf John Peter III

VP, General Counsel

Officer
12,250 -100.0%
21.08
US$258,194 		12,250 -100.0% 21.08 US$258,194
2011-11-08 2011-11-07 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
200 -1.0%
21.01
US$4,202 		200 -1.0% 21.01 US$4,202
2011-11-08 2011-11-07 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
19,800 -50.2%
21.00
US$415,800 		19,800 -50.2% 21.00 US$415,800
2011-11-02 2011-11-01 PlS Planned sale Broom Colin MD

VP & Chief Scientific Officer

Officer
24,121 -55.4%
20.05
US$483,641 		24,121 -55.4% 20.05 US$483,641
2011-11-02 2011-10-31 S Sale Broom Colin MD

VP & Chief Scientific Officer

Officer
20,495 -51.3%
20.42
US$418,555 		20,495 -51.3% 20.42 US$418,555
2011-10-06 2011-10-05 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
145,763 +1.6%
18.18
US$2,650,423 		145,763 +1.6% 18.18 US$2,650,423
2011-10-06 2011-10-05 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
16,278 +0.9%
18.18
US$295,985 		16,278 +0.9% 18.18 US$295,985
2011-10-06 2011-10-05 B Purchase 14159 capital (GP), LLC Large shareholder
6,017 +2.1%
18.18
US$109,408 		6,017 +2.1% 18.18 US$109,408
2011-10-06 2011-10-04 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
45,584 +0.5%
17.48
US$796,644 		45,584 +0.5% 17.48 US$796,644
2011-10-06 2011-10-04 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
2,511 +0.1%
17.48
US$43,883 		2,511 +0.1% 17.48 US$43,883
2011-10-06 2011-10-04 B Purchase 14159 capital (GP), LLC Large shareholder
1,905 +0.7%
17.48
US$33,293 		1,905 +0.7% 17.48 US$33,293
2011-10-03 2011-10-03 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
445,574 +5.0%
17.71
US$7,890,269 		445,574 +5.0% 17.71 US$7,890,269
2011-10-03 2011-10-03 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
70,629 +0.8%
17.62
US$1,244,589 		70,629 +0.8% 17.62 US$1,244,589
2011-10-03 2011-09-30 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
88,657 +1.0%
18.08
US$1,602,892 		88,657 +1.0% 18.08 US$1,602,892
2011-10-03 2011-09-30 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
43,321 +0.5%
18.19
US$788,122 		43,321 +0.5% 18.19 US$788,122
2011-10-03 2011-09-30 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
13,576 +0.7%
18.08
US$245,450 		13,576 +0.7% 18.08 US$245,450
2011-10-03 2011-09-30 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
6,634 +0.4%
18.19
US$120,690 		6,634 +0.4% 18.19 US$120,690
2011-10-03 2011-09-30 B Purchase 14159 capital (GP), LLC Large shareholder
3,367 +1.2%
18.08
US$60,874 		3,367 +1.2% 18.08 US$60,874
2011-10-03 2011-09-30 B Purchase 14159 capital (GP), LLC Large shareholder
1,645 +0.6%
18.19
US$29,927 		1,645 +0.6% 18.19 US$29,927
2011-10-03 2011-09-29 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
159,945 +1.9%
18.00
US$2,878,882 		159,945 +1.9% 18.00 US$2,878,882
2011-10-03 2011-09-29 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
21,117 +1.1%
18.00
US$380,089 		21,117 +1.1% 18.00 US$380,089
2011-10-03 2011-09-29 B Purchase 14159 capital (GP), LLC Large shareholder
6,084 +2.2%
18.00
US$109,507 		6,084 +2.2% 18.00 US$109,507
2011-10-03 2011-09-29 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
89,970 +1.1%
17.97
US$1,616,392 		89,970 +1.1% 17.97 US$1,616,392
2011-10-03 2011-09-29 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
11,878 +0.6%
17.97
US$213,399 		11,878 +0.6% 17.97 US$213,399
2011-10-03 2011-09-29 B Purchase 14159 capital (GP), LLC Large shareholder
3,423 +1.3%
17.97
US$61,497 		3,423 +1.3% 17.97 US$61,497
2011-09-26 2011-09-26 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
4,697 +0.3%
18.13
US$85,155 		4,697 +0.3% 18.13 US$85,155
2011-09-26 2011-09-26 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
22,084 +1.2%
18.13
US$400,295 		22,084 +1.2% 18.13 US$400,295
2011-09-26 2011-09-26 B Purchase 14159 capital (GP), LLC Large shareholder
1,103 +0.4%
18.13
US$19,997 		1,103 +0.4% 18.13 US$19,997
2011-09-26 2011-09-26 B Purchase 14159 capital (GP), LLC Large shareholder
5,184 +1.9%
18.13
US$93,965 		5,184 +1.9% 18.13 US$93,965
2011-09-26 2011-09-26 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
28,000 +0.3%
18.13
US$507,632 		28,000 +0.3% 18.13 US$507,632
2011-09-26 2011-09-26 B Purchase Baker Brothers Life Sciences Capital (GP), LLC Large shareholder
131,641 +1.6%
18.13
US$2,386,125 		131,641 +1.6% 18.13 US$2,386,125
2011-09-26 2011-09-23 B Purchase Baker Biotech Capital (GP), LLC Large shareholder
8,828 +0.5%
17.78
US$156,988 		8,828 +0.5% 17.78 US$156,988
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