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United States Biotechnology & Medical Research

Tango Therapeutics Inc (TNGX)

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Over the last 90 days, Tango Therapeutics Inc. has seen significant insider selling, with a net value of -$241,320. Notably, a former affiliate and an officer have engaged in large proposed sales totaling over $164 million. Executive selling accounts for the entire net negative value, indicating a trend of divestment among top personnel.
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Ticker: TNGX Exchange: NMS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
Nextech Crossover I SCSp
Former Affiliate
1 sale — total 100,000 USD
Proposed sale 17 Jun 2026
Value US$4,624,343.41 | Price 384.34 | Shares 92,587
Proposed sale 11 Jun 2026
Value US$1,669,728.19 | Price 460.70 | Shares 30,995
Proposed sale 10 Jun 2026
Value US$100,000.00 | Price 30.00 | Shares 1,000
Planned sale 1 Jun 2026
Value US$100,000.00 | Price 23.06 | Shares 1,000
Planned sale 1 Jun 2026
Value US$100,000.00 | Price 22.25 | Shares 1,000
Planned sale 1 May 2026
Value US$24,196.04 | Price 22.00 | Shares 1,100
Planned sale 1 May 2026
Value US$548,901.29 | Price 21.19 | Shares 25,900
Proposed sale 1 May 2026
Value US$1,415,245.20 | Price 21.62 | Shares 65,460
Planned sale 15 Apr 2026
Value US$961,500.00 | Price 25.00 | Shares 38,460
Planned sale 1 Apr 2026
Value US$572,478.30 | Price 21.20 | Shares 27,000
Sale 25 Mar 2026
Value US$241,320.00 | Price 20.11 | Shares 12,000
Proposed sale 25 Mar 2026
Value US$1,811,640.00 | Price 19.48 | Shares 93,000
Planned sale 5 Mar 2026
Value US$303,765.00 | Price 15.00 | Shares 20,251
Proposed sale 5 Mar 2026
Value US$250,099.85 | Price 12.35 | Shares 20,251
Planned sale 25 Feb 2026
Value US$694,208.46 | Price 12.77 | Shares 54,345
Proposed sale 25 Feb 2026
Value US$699,963.60 | Price 12.88 | Shares 54,345
Sale 3 Feb 2026
Value US$1,457.37 | Price 12.90 | Shares 113
Sale 3 Feb 2026
Value US$125,073.49 | Price 12.26 | Shares 10,204
Sale 3 Feb 2026
Value US$1,457.37 | Price 12.90 | Shares 113
Sale 3 Feb 2026
Value US$125,073.49 | Price 12.26 | Shares 10,204
Sale 3 Feb 2026
Value US$2,592.32 | Price 12.90 | Shares 201
Sale 3 Feb 2026
Value US$223,707.98 | Price 12.26 | Shares 18,251
Sale 3 Feb 2026
Value US$2,592.32 | Price 12.90 | Shares 201
Sale 3 Feb 2026
Value US$223,707.98 | Price 12.26 | Shares 18,251
Sale 3 Feb 2026
Value US$4,294.73 | Price 12.90 | Shares 333
Sale 3 Feb 2026
Value US$369,998.86 | Price 12.26 | Shares 30,186
Sale 3 Feb 2026
Value US$4,294.73 | Price 12.90 | Shares 333
Sale 3 Feb 2026
Value US$369,998.86 | Price 12.26 | Shares 30,186
Sale 23 Oct 2025
Value US$4,846,574.95 | Price 10.15 | Shares 477,401
Proposed sale 23 Oct 2025
Value US$3,594,829.53 | Price 7.53 | Shares 477,401
Sale 25 Sep 2025
Value US$4,008,500.00 | Price 8.02 | Shares 500,000
Proposed sale 25 Sep 2025
Value US$3,900,000.00 | Price 7.80 | Shares 500,000
Proposed sale 16 Sep 2025
Value US$2,672,026.35 | Price 7.35 | Shares 363,541
Sale 16 Sep 2025
Value US$2,559,328.64 | Price 7.04 | Shares 363,541
Sale 8 Sep 2025
Value US$608,628.13 | Price 7.04 | Shares 86,459
Proposed sale 8 Sep 2025
Value US$608,628.13 | Price 7.04 | Shares 86,459
Sale 5 Sep 2025
Value US$4,500,342.00 | Price 7.00 | Shares 642,906
Proposed sale 5 Sep 2025
Value US$4,461,767.00 | Price 6.94 | Shares 642,906
Sale 22 Aug 2025
Value US$2,115,358.00 | Price 7.00 | Shares 302,194
Proposed sale 22 Aug 2025
Value US$2,085,138.60 | Price 6.90 | Shares 302,194
Sale 19 Aug 2025
Value US$7,712,760.00 | Price 7.01 | Shares 1,100,000
Proposed sale 19 Aug 2025
Value US$7,656,000.00 | Price 6.96 | Shares 1,100,000
Sale 5 Feb 2025
Value US$8,080.54 | Price 3.16 | Shares 2,556
Sale 5 Feb 2025
Value US$12,481.21 | Price 3.16 | Shares 3,948
Sale 5 Feb 2025
Value US$28,493.70 | Price 3.16 | Shares 9,013
Sale 5 Feb 2025
Value US$21,658.75 | Price 3.16 | Shares 6,851
Sale 4 Feb 2025
Value US$8,288.71 | Price 2.99 | Shares 2,774
Sale 4 Feb 2025
Value US$12,800.59 | Price 2.99 | Shares 4,284
Sale 4 Feb 2025
Value US$29,216.66 | Price 2.99 | Shares 9,778
Sale 4 Feb 2025
Value US$22,206.82 | Price 2.99 | Shares 7,432
Buy 18 Nov 2024
Value US$37,800.00 | Price 3.78 | Shares 10,000
Buy 14 Nov 2024
Value US$36,200.00 | Price 3.62 | Shares 10,000
Sale 7 Nov 2024
Value US$3,334,607.02 | Price 2.92 | Shares 1,143,124
Sale 7 Nov 2024
Value US$205,113.47 | Price 3.29 | Shares 62,318
Sale 6 Nov 2024
Value US$4,896,022.55 | Price 3.28 | Shares 1,494,558
Sale 6 Nov 2024
Value US$9,671,200.00 | Price 3.14 | Shares 3,080,000
Proposed sale 6 Nov 2024
Value US$1,813,000.00 | Price 5.18 | Shares 350,000
Proposed sale 6 Nov 2024
Value US$6,347,572.00 | Price 5.18 | Shares 1,225,400
Proposed sale 6 Nov 2024
Value US$4,046,487.00 | Price 5.18 | Shares 781,175
Proposed sale 6 Nov 2024
Value US$216,913.00 | Price 5.18 | Shares 41,875
Proposed sale 6 Nov 2024
Value US$259,000.00 | Price 5.18 | Shares 50,000
Proposed sale 6 Nov 2024
Value US$292,929.00 | Price 5.18 | Shares 56,550
Proposed sale 6 Nov 2024
Value US$2,978,500.00 | Price 5.18 | Shares 575,000
Sale 25 Oct 2024
Value US$4,348,710.00 | Price 6.87 | Shares 633,000
Proposed sale 25 Oct 2024
Value US$3,352,570.00 | Price 6.29 | Shares 533,000
Proposed sale 25 Oct 2024
Value US$629,000.00 | Price 6.29 | Shares 100,000
Sale 22 Oct 2024
Value US$1,695,000.00 | Price 6.78 | Shares 250,000
Proposed sale 22 Oct 2024
Value US$357,500.00 | Price 7.15 | Shares 50,000
Proposed sale 22 Oct 2024
Value US$517,660.00 | Price 7.15 | Shares 72,400
Proposed sale 22 Oct 2024
Value US$912,340.00 | Price 7.15 | Shares 127,600
Sale 21 Oct 2024
Value US$4,406,250.00 | Price 7.05 | Shares 625,000
Proposed sale 21 Oct 2024
Value US$932,500.00 | Price 7.46 | Shares 125,000
Proposed sale 21 Oct 2024
Value US$3,730,000.00 | Price 7.46 | Shares 500,000
Sale 13 Sep 2024
Value US$709,755.70 | Price 10.53 | Shares 67,400
Proposed sale 13 Sep 2024
Value US$707,700.00 | Price 10.50 | Shares 67,400
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-06-17 2026-06-17 PrS Proposed sale
Nextech Crossover I SCSp

Former Affiliate
92,587
384.34
US$4,624,343 		92,587 384.34 US$4,624,343
2026-06-11 2026-06-11 PrS Proposed sale
1.7
DANIELLA BECKMAN

Officer

Officer
30,995
460.70
US$1,669,728 		30,995 460.70 US$1,669,728
2026-06-10 2026-06-10 PrS Proposed sale
1.7
DANIELLA BECKMAN

Officer

Officer
67,729
424.09
US$2,362,618 		67,729 424.09 US$2,362,618
2026-06-03 2026-06-01 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
1,000 -15.3%
23.06
US$100,000 		1,000 -15.3% 23.06 US$100,000
2026-06-03 2026-06-01 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
1,000 -4.3%
22.25
US$100,000 		1,000 -4.3% 22.25 US$100,000
2026-05-05 2026-05-01 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
1,100 -0.9%
22.00
US$24,196 		1,100 -0.9% 22.00 US$24,196
2026-05-05 2026-05-01 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
25,900 -18.1%
21.19
US$548,901 		25,900 -18.1% 21.19 US$548,901
2026-05-01 2026-05-01 PrS Proposed sale
1.7
ADAM CRYSTAL

Officer

Officer
65,460
21.62
US$1,415,245 		65,460 21.62 US$1,415,245
2026-04-16 2026-04-15 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
38,460 -25.5%
25.00
US$961,500 		38,460 -25.5% 25.00 US$961,500
2026-04-02 2026-04-01 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
27,000 -19.3%
21.20
US$572,478 		27,000 -19.3% 21.20 US$572,478
2026-03-27 2026-03-25 S Sale
1.7
Crystal Adam

President, R&D

Officer
12,000 -9.6%
20.11
US$241,320 		12,000 -9.6% 20.11 US$241,320
2026-03-25 2026-03-25 PrS Proposed sale
1.7
ADAM CRYSTAL

Officer

Officer
93,000
19.48
US$1,811,640 		93,000 19.48 US$1,811,640
2026-03-09 2026-03-05 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
20,251 -15.2%
15.00
US$303,765 		20,251 -15.2% 15.00 US$303,765
2026-03-05 2026-03-05 PrS Proposed sale
1.7
ADAM CRYSTAL

Officer

Officer
20,251
12.35
US$250,100 		20,251 12.35 US$250,100
2026-02-27 2026-02-25 PlS Planned sale
1.7
Crystal Adam

President, R&D

Officer
54,345 -29.0%
12.77
US$694,208 		54,345 -29.0% 12.77 US$694,208
2026-02-25 2026-02-25 PrS Proposed sale
1.7
ADAM CRYSTAL

Officer

Officer
54,345
12.88
US$699,964 		54,345 12.88 US$699,964
2026-02-04 2026-02-03 S Sale
1.7
Beckman Daniella

Chief Financial Officer

Officer
113 -0.1%
12.90
US$1,457 		113 -0.1% 12.90 US$1,457
2026-02-04 2026-02-03 S Sale
1.7
Beckman Daniella

Chief Financial Officer

Officer
10,204 -5.2%
12.26
US$125,073 		10,204 -5.2% 12.26 US$125,073
2026-02-04 2026-02-03 S Sale
1.7
Crystal Adam

President, R&D

Officer
201 -0.1%
12.90
US$2,592 		201 -0.1% 12.90 US$2,592
2026-02-04 2026-02-03 S Sale
1.7
Crystal Adam

President, R&D

Officer
18,251 -8.9%
12.26
US$223,708 		18,251 -8.9% 12.26 US$223,708
2026-02-04 2026-02-03 S Sale
1.7
Weber Barbara

Director, Executive Chair

Executive Director
333 -0.0%
12.90
US$4,295 		333 -0.0% 12.90 US$4,295
2026-02-04 2026-02-03 S Sale
1.7
Weber Barbara

Director, Executive Chair

Executive Director
30,186 -1.8%
12.26
US$369,999 		30,186 -1.8% 12.26 US$369,999
2026-02-04 2026-02-03 S Sale
1.7
Beckman Daniella

Chief Financial Officer

Officer
113 -0.1%
12.90
US$1,457 		113 -0.1% 12.90 US$1,457
2026-02-04 2026-02-03 S Sale
1.7
Beckman Daniella

Chief Financial Officer

Officer
10,204 -5.2%
12.26
US$125,073 		10,204 -5.2% 12.26 US$125,073
2026-02-04 2026-02-03 S Sale
1.7
Crystal Adam

President, R&D

Officer
201 -0.1%
12.90
US$2,592 		201 -0.1% 12.90 US$2,592
2026-02-04 2026-02-03 S Sale
1.7
Crystal Adam

President, R&D

Officer
18,251 -8.9%
12.26
US$223,708 		18,251 -8.9% 12.26 US$223,708
2026-02-04 2026-02-03 S Sale
1.7
Weber Barbara

Director, Executive Chair

Executive Director
333 -0.0%
12.90
US$4,295 		333 -0.0% 12.90 US$4,295
2026-02-04 2026-02-03 S Sale
1.7
Weber Barbara

Director, Executive Chair

Executive Director
30,186 -1.8%
12.26
US$369,999 		30,186 -1.8% 12.26 US$369,999
2025-10-27 2025-10-23 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
477,401 -3.4%
10.15
US$4,846,575 		477,401 -3.4% 10.15 US$4,846,575
2025-10-23 2025-10-23 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

10% Stockholder

Large shareholder
477,401
7.53
US$3,594,830 		477,401 7.53 US$3,594,830
2025-09-29 2025-09-25 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
500,000 -3.5%
8.02
US$4,008,500 		500,000 -3.5% 8.02 US$4,008,500
2025-09-25 2025-09-25 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

10% Stockholder

Large shareholder
500,000
7.80
US$3,900,000 		500,000 7.80 US$3,900,000
2025-09-17 2025-09-16 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

10% Stockholder

Large shareholder
363,541
7.35
US$2,672,026 		363,541 7.35 US$2,672,026
2025-09-17 2025-09-16 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
363,541 -2.5%
7.04
US$2,559,329 		363,541 -2.5% 7.04 US$2,559,329
2025-09-09 2025-09-08 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
86,459 -0.6%
7.04
US$608,628 		86,459 -0.6% 7.04 US$608,628
2025-09-08 2025-09-08 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

10% Stockholder

Large shareholder
86,459
7.04
US$608,628 		86,459 7.04 US$608,628
2025-09-09 2025-09-05 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
642,906 -4.2%
7.00
US$4,500,342 		642,906 -4.2% 7.00 US$4,500,342
2025-09-05 2025-09-05 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

10% Stockholder

Large shareholder
642,906
6.94
US$4,461,767 		642,906 6.94 US$4,461,767
2025-08-26 2025-08-22 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
302,194 -1.9%
7.00
US$2,115,358 		302,194 -1.9% 7.00 US$2,115,358
2025-08-22 2025-08-22 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

10% Stockholder

Large shareholder
302,194
6.90
US$2,085,139 		302,194 6.90 US$2,085,139
2025-08-21 2025-08-19 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
1,100,000 -6.5%
7.01
US$7,712,760 		1,100,000 -6.5% 7.01 US$7,712,760
2025-08-19 2025-08-19 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

10% Stockholder

Large shareholder
1,100,000
6.96
US$7,656,000 		1,100,000 6.96 US$7,656,000
2025-02-06 2025-02-05 S Sale
3.8
Barry Douglas

General Counsel

Officer
2,556 -3.7%
3.16
US$8,081 		2,556 -3.7% 3.16 US$8,081
2025-02-06 2025-02-05 S Sale
1.7
Beckman Daniella

Chief Financial Officer

Officer
3,948 -2.6%
3.16
US$12,481 		3,948 -2.6% 3.16 US$12,481
2025-02-06 2025-02-05 S Sale
1.7
Weber Barbara

Chief Executive Officer

Executive Director
9,013 -0.6%
3.16
US$28,494 		9,013 -0.6% 3.16 US$28,494
2025-02-06 2025-02-05 S Sale
1.7
Crystal Adam

See Remarks

Officer
6,851 -4.2%
3.16
US$21,659 		6,851 -4.2% 3.16 US$21,659
2025-02-06 2025-02-04 S Sale
3.8
Barry Douglas

General Counsel

Officer
2,774 -3.9%
2.99
US$8,289 		2,774 -3.9% 2.99 US$8,289
2025-02-06 2025-02-04 S Sale
1.7
Beckman Daniella

Chief Financial Officer

Officer
4,284 -2.7%
2.99
US$12,801 		4,284 -2.7% 2.99 US$12,801
2025-02-06 2025-02-04 S Sale
1.7
Weber Barbara

Chief Executive Officer

Executive Director
9,778 -0.6%
2.99
US$29,217 		9,778 -0.6% 2.99 US$29,217
2025-02-06 2025-02-04 S Sale
1.7
Crystal Adam

See Remarks

Officer
7,432 -4.3%
2.99
US$22,207 		7,432 -4.3% 2.99 US$22,207
2024-11-18 2024-11-18 B Purchase
0.9
Rothenberg Mace
Non-Executive Director
10,000 +47.1%
3.78
US$37,800 		10,000 +47.1% 3.78 US$37,800
2024-11-18 2024-11-14 B Purchase
0.9
Rothenberg Mace
Non-Executive Director
10,000 +88.9%
3.62
US$36,200 		10,000 +88.9% 3.62 US$36,200
2024-11-08 2024-11-07 S Sale
3.1
EcoR1 Capital, LLC
Large shareholder
1,143,124 -9.7%
2.92
US$3,334,607 		1,143,124 -9.7% 2.92 US$3,334,607
2024-11-08 2024-11-07 S Sale
3.1
EcoR1 Capital, LLC
Large shareholder
62,318 -0.5%
3.29
US$205,113 		62,318 -0.5% 3.29 US$205,113
2024-11-08 2024-11-06 S Sale
3.1
EcoR1 Capital, LLC
Large shareholder
1,494,558 -11.2%
3.28
US$4,896,023 		1,494,558 -11.2% 3.28 US$4,896,023
2024-11-07 2024-11-06 S Sale
3.4
Boxer Capital Management, LLC

See remarks
3,080,000 -46.0%
3.14
US$9,671,200 		3,080,000 -46.0% 3.14 US$9,671,200
2024-11-06 2024-11-06 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group formerly owning 10% of the shares

Large shareholder
350,000
5.18
US$1,813,000 		350,000 5.18 US$1,813,000
2024-11-06 2024-11-06 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group formerly owning 10% of the shares

Large shareholder
1,225,400
5.18
US$6,347,572 		1,225,400 5.18 US$6,347,572
2024-11-06 2024-11-06 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group formerly owning 10% of the shares

Large shareholder
781,175
5.18
US$4,046,487 		781,175 5.18 US$4,046,487
2024-11-06 2024-11-06 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group formerly owning 10% of the shares

Large shareholder
41,875
5.18
US$216,913 		41,875 5.18 US$216,913
2024-11-06 2024-11-06 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group formerly owning 10% of the shares

Large shareholder
50,000
5.18
US$259,000 		50,000 5.18 US$259,000
2024-11-06 2024-11-06 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group formerly owning 10% of the shares

Large shareholder
56,550
5.18
US$292,929 		56,550 5.18 US$292,929
2024-11-06 2024-11-06 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group formerly owning 10% of the shares

Large shareholder
575,000
5.18
US$2,978,500 		575,000 5.18 US$2,978,500
2024-10-28 2024-10-25 S Sale
3.4
Boxer Capital Management, LLC

See remarks.
633,000 -8.6%
6.87
US$4,348,710 		633,000 -8.6% 6.87 US$4,348,710
2024-10-25 2024-10-25 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group owning over 10% of the shares

Large shareholder
533,000
6.29
US$3,352,570 		533,000 6.29 US$3,352,570
2024-10-25 2024-10-25 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group owning over 10% of the shares

Large shareholder
100,000
6.29
US$629,000 		100,000 6.29 US$629,000
2024-10-23 2024-10-22 S Sale
3.4
Boxer Capital Management, LLC

See remarks
250,000 -3.3%
6.78
US$1,695,000 		250,000 -3.3% 6.78 US$1,695,000
2024-10-22 2024-10-22 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group owning over 10% of the shares

Large shareholder
50,000
7.15
US$357,500 		50,000 7.15 US$357,500
2024-10-22 2024-10-22 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group owning over 10% of the shares

Large shareholder
72,400
7.15
US$517,660 		72,400 7.15 US$517,660
2024-10-22 2024-10-22 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group owning over 10% of the shares

Large shareholder
127,600
7.15
US$912,340 		127,600 7.15 US$912,340
2024-10-23 2024-10-21 S Sale
3.4
Boxer Capital Management, LLC

See remarks
625,000 -7.6%
7.05
US$4,406,250 		625,000 -7.6% 7.05 US$4,406,250
2024-10-22 2024-10-21 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group owning over 10% of the shares

Large shareholder
125,000
7.46
US$932,500 		125,000 7.46 US$932,500
2024-10-22 2024-10-21 PrS Proposed sale
3.4
Boxer Capital Management, LLC

Member of group owning over 10% of the shares

Large shareholder
500,000
7.46
US$3,730,000 		500,000 7.46 US$3,730,000
2024-09-17 2024-09-13 S Sale
3.3
Third Rock Ventures IV, L.P.
Large shareholder
67,400 -0.4%
10.53
US$709,756 		67,400 -0.4% 10.53 US$709,756
2024-09-13 2024-09-13 PrS Proposed sale
3.3
Third Rock Ventures IV, L.P.

Affiliate
67,400
10.50
US$707,700 		67,400 10.50 US$707,700
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