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Ticker: OTIC Exchange: NSM


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Purchase Sale Planned purchase Planned sale Net purchase Net sale
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Total value Details
March 3, 2021 March 3, 2021 S Sale

Lichter Jay

Non-Executive Director
113,935 -100.0%
2.70
307,397 USD
113,935 -100.0% 2.70 307,397 USD
March 3, 2021 March 3, 2021 S Sale

Lichter Jay

Non-Executive Director
207,245 -100.0%
2.70
559,147 USD
207,245 -100.0% 2.70 559,147 USD
March 2, 2021 March 2, 2021 S Sale

Lichter Jay

Non-Executive Director
138,199 -54.8%
2.90
400,639 USD
138,199 -54.8% 2.90 400,639 USD
March 2, 2021 March 2, 2021 S Sale

Lichter Jay

Non-Executive Director
251,375 -54.8%
2.90
728,736 USD
251,375 -54.8% 2.90 728,736 USD
March 2, 2021 March 1, 2021 S Sale

Lichter Jay

Non-Executive Director
61,619 -19.6%
2.86
175,984 USD
61,619 -19.6% 2.86 175,984 USD
March 2, 2021 March 1, 2021 S Sale

Lichter Jay

Non-Executive Director
112,081 -19.6%
2.86
320,103 USD
112,081 -19.6% 2.86 320,103 USD
March 2, 2021 Feb. 26, 2021 S Sale

Lichter Jay

Non-Executive Director
117,262 -27.2%
2.83
331,851 USD
117,262 -27.2% 2.83 331,851 USD
March 2, 2021 Feb. 26, 2021 S Sale

Lichter Jay

Non-Executive Director
213,292 -27.2%
2.83
603,616 USD
213,292 -27.2% 2.83 603,616 USD
Feb. 25, 2021 Feb. 25, 2021 S Sale

Lichter Jay

Non-Executive Director
110,361 -20.4%
2.95
326,006 USD
110,361 -20.4% 2.95 326,006 USD
Feb. 25, 2021 Feb. 25, 2021 S Sale

Lichter Jay

Non-Executive Director
200,739 -20.4%
2.95
592,983 USD
200,739 -20.4% 2.95 592,983 USD
Feb. 25, 2021 Feb. 24, 2021 S Sale

Lichter Jay

Non-Executive Director
178,484 -24.8%
2.98
532,239 USD
178,484 -24.8% 2.98 532,239 USD
Feb. 25, 2021 Feb. 24, 2021 S Sale

Lichter Jay

Non-Executive Director
324,651 -24.8%
2.98
968,109 USD
324,651 -24.8% 2.98 968,109 USD
Feb. 25, 2021 Feb. 23, 2021 S Sale

Lichter Jay

Non-Executive Director
95,113 -11.7%
2.89
274,686 USD
95,113 -11.7% 2.89 274,686 USD
Feb. 25, 2021 Feb. 23, 2021 S Sale

Lichter Jay

Non-Executive Director
173,005 -11.7%
2.89
499,638 USD
173,005 -11.7% 2.89 499,638 USD
June 27, 2017 June 26, 2017 PS Planned sale

LOUMEAU ERIC J

GC & Chief Compliance Officer
1,206 -100.0%
18.75
22,613 USD
1,206 -100.0% 18.75 22,613 USD
June 27, 2017 June 23, 2017 PS Planned sale

LOUMEAU ERIC J

GC & Chief Compliance Officer
2,316 -65.8%
18.50
42,846 USD
2,316 -65.8% 18.50 42,846 USD
Nov. 22, 2016 Nov. 21, 2016 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
1,456 -13.3%
18.07
26,303 USD
1,456 -13.3% 18.07 26,303 USD
Nov. 22, 2016 Nov. 18, 2016 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
9,169 -49.2%
18.07
165,703 USD
9,169 -49.2% 18.07 165,703 USD
Sept. 8, 2016 Sept. 6, 2016 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
5,304 -35.9%
17.95
95,207 USD
5,304 -35.9% 17.95 95,207 USD
Sept. 8, 2016 Sept. 6, 2016 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
3,813 -20.5%
17.95
68,443 USD
3,813 -20.5% 17.95 68,443 USD
Sept. 8, 2016 Sept. 6, 2016 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
12,133 -39.5%
17.95
217,787 USD
12,133 -39.5% 17.95 217,787 USD
Dec. 22, 2015 Dec. 21, 2015 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
8,061 -47.5%
28.38
228,753 USD
8,061 -47.5% 28.38 228,753 USD
Dec. 22, 2015 Dec. 21, 2015 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
13,189 -43.7%
27.83
367,074 USD
13,189 -43.7% 27.83 367,074 USD
Dec. 18, 2015 Dec. 17, 2015 PS Planned sale

Cayer Paul E

Ch. Financial & Business Offcr Officer
300 -3.0%
30.19
9,056 USD
300 -3.0% 30.19 9,056 USD
Dec. 18, 2015 Dec. 17, 2015 PS Planned sale

Cayer Paul E

Ch. Financial & Business Offcr Officer
2,700 -21.4%
29.65
80,045 USD
2,700 -21.4% 29.65 80,045 USD
Dec. 16, 2015 Dec. 15, 2015 PS Planned sale

Weber David Allen

President & CEO Executive Director
5,208 -22.8%
27.25
141,917 USD
5,208 -22.8% 27.25 141,917 USD
Dec. 16, 2015 Dec. 14, 2015 S Sale

Savel Robert Michael II

Chief Technical Officer Officer
100 -7.4%
27.70
2,770 USD
100 -7.4% 27.70 2,770 USD
Dec. 16, 2015 Dec. 14, 2015 S Sale

Savel Robert Michael II

Chief Technical Officer Officer
1,289 -48.7%
27.26
35,136 USD
1,289 -48.7% 27.26 35,136 USD
Dec. 16, 2015 Dec. 14, 2015 S Sale

Savel Robert Michael II

Chief Technical Officer Officer
1,289 -32.8%
26.15
33,706 USD
1,289 -32.8% 26.15 33,706 USD
Dec. 16, 2015 Dec. 14, 2015 PS Planned sale

Savel Robert Michael II

Chief Technical Officer Officer
2,322 -37.1%
25.14
58,363 USD
2,322 -37.1% 25.14 58,363 USD
Nov. 30, 2015 Nov. 30, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
590 -0.0%
29.22
17,240 USD
590 -0.0% 29.22 17,240 USD
Nov. 30, 2015 Nov. 30, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
2,716 -0.1%
28.64
77,786 USD
2,716 -0.1% 28.64 77,786 USD
Nov. 30, 2015 Nov. 30, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
590 -0.0%
29.22
17,240 USD
590 -0.0% 29.22 17,240 USD
Nov. 30, 2015 Nov. 30, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
2,716 -0.1%
28.64
77,786 USD
2,716 -0.1% 28.64 77,786 USD
Nov. 30, 2015 Nov. 27, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
29,000 -1.5%
28.97
840,130 USD
29,000 -1.5% 28.97 840,130 USD
Nov. 30, 2015 Nov. 27, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
29,000 -1.5%
28.97
840,130 USD
29,000 -1.5% 28.97 840,130 USD
Nov. 30, 2015 Nov. 25, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
34,800 -1.8%
28.91
1,006,068 USD
34,800 -1.8% 28.91 1,006,068 USD
Nov. 30, 2015 Nov. 25, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
34,800 -1.8%
28.91
1,006,068 USD
34,800 -1.8% 28.91 1,006,068 USD
Nov. 24, 2015 Nov. 24, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
36,100 -1.8%
28.75
1,037,875 USD
36,100 -1.8% 28.75 1,037,875 USD
Nov. 24, 2015 Nov. 24, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
36,100 -1.8%
28.75
1,037,875 USD
36,100 -1.8% 28.75 1,037,875 USD
Nov. 24, 2015 Nov. 23, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
80,800 -4.0%
28.45
2,298,760 USD
80,800 -4.0% 28.45 2,298,760 USD
Nov. 24, 2015 Nov. 23, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
80,800 -4.0%
28.45
2,298,760 USD
80,800 -4.0% 28.45 2,298,760 USD
Nov. 24, 2015 Nov. 20, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
83,900 -4.0%
28.59
2,398,701 USD
83,900 -4.0% 28.59 2,398,701 USD
Nov. 24, 2015 Nov. 20, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
83,900 -4.0%
28.59
2,398,701 USD
83,900 -4.0% 28.59 2,398,701 USD
Nov. 19, 2015 Nov. 19, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
127,300 -5.7%
28.60
3,640,780 USD
127,300 -5.7% 28.60 3,640,780 USD
Nov. 19, 2015 Nov. 19, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
127,300 -5.7%
28.60
3,640,780 USD
127,300 -5.7% 28.60 3,640,780 USD
Nov. 19, 2015 Nov. 17, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
200 -0.0%
29.09
5,818 USD
200 -0.0% 29.09 5,818 USD
Nov. 19, 2015 Nov. 17, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
200 -0.0%
29.09
5,818 USD
200 -0.0% 29.09 5,818 USD
Nov. 19, 2015 Nov. 17, 2015 S Sale

ORBIMED ADVISORS LLC

Non-Executive Director
10,898 -0.5%
28.80
313,862 USD
10,898 -0.5% 28.80 313,862 USD
Nov. 19, 2015 Nov. 17, 2015 S Sale

Khuong Chau Quang

Non-Executive Director
10,898 -0.5%
28.80
313,862 USD
10,898 -0.5% 28.80 313,862 USD
Nov. 17, 2015 Nov. 17, 2015 PS Planned sale

Cayer Paul E

Ch. Financial & Business Offcr Officer
3,000 -23.8%
28.69
86,057 USD
3,000 -23.8% 28.69 86,057 USD
Nov. 17, 2015 Nov. 16, 2015 S Sale

Weber David Allen

President & CEO Executive Director
100 -0.6%
29.25
2,925 USD
100 -0.6% 29.25 2,925 USD
Nov. 17, 2015 Nov. 16, 2015 PS Planned sale

Weber David Allen

President & CEO Executive Director
5,108 -22.4%
28.56
145,887 USD
5,108 -22.4% 28.56 145,887 USD
Nov. 13, 2015 Nov. 13, 2015 PS Planned sale

Weber David Allen

President & CEO Executive Director
10,416 -95.1%
30.95
322,375 USD
10,416 -95.1% 30.95 322,375 USD
Nov. 12, 2015 Nov. 11, 2015 PS Planned sale

Cayer Paul E

CFO/Ch. Business Offcr & Sec. Officer
3,000 -23.8%
24.95
74,850 USD
3,000 -23.8% 24.95 74,850 USD
Nov. 12, 2015 Nov. 11, 2015 PS Planned sale

Weber David Allen

President & CEO Executive Director
5,208 -90.6%
24.95
129,940 USD
5,208 -90.6% 24.95 129,940 USD
Sept. 22, 2015 Sept. 21, 2015 PS Planned sale

LeBel Carl

Chief Scientific Officer Officer
21,250 -70.4%
24.36
517,576 USD
21,250 -70.4% 24.36 517,576 USD
Sept. 18, 2015 Sept. 17, 2015 PS Planned sale

Cayer Paul E

CFO/Ch. Business Offcr & Sec. Officer
3,000 -23.8%
24.95
74,850 USD
3,000 -23.8% 24.95 74,850 USD
Sept. 16, 2015 Sept. 15, 2015 PS Planned sale

Weber David Allen

President & CEO Executive Director
5,216 -90.6%
24.95
130,139 USD
5,216 -90.6% 24.95 130,139 USD
Sept. 15, 2015 Sept. 14, 2015 PS Planned sale

Savel Robert Michael II

Chief Technical Officer Officer
5,000 -79.9%
23.98
119,897 USD
5,000 -79.9% 23.98 119,897 USD
June 17, 2015 June 15, 2015 PS Planned sale

Savel Robert Michael II

Chief Technical Officer Officer
25,000 -95.2%
23.73
593,285 USD
25,000 -95.2% 23.73 593,285 USD
May 27, 2015 May 22, 2015 B Purchase

CAPPS VICKIE L

Non-Executive Director
1,600 +inf%
24.35
38,960 USD
1,600 +inf% 24.35 38,960 USD
May 27, 2015 May 22, 2015 B Purchase

CAPPS VICKIE L

Non-Executive Director
3,400 +inf%
24.36
82,808 USD
3,400 +inf% 24.36 82,808 USD
Aug. 21, 2014 Aug. 19, 2014 B Purchase

Novo A/S

SEE REMARKS Major owner
15,690 +0.7%
15.50
243,135 USD
15,690 +0.7% 15.50 243,135 USD
Aug. 19, 2014 Aug. 18, 2014 B Purchase

Novo A/S

SEE REMARKS Major owner
171,875 +8.6%
16.00
2,750,000 USD
171,875 +8.6% 16.00 2,750,000 USD
Aug. 19, 2014 Aug. 18, 2014 B Purchase

Avalon Ventures VIII LP

Major owner
109,375 +15.5%
16.00
1,750,000 USD
109,375 +15.5% 16.00 1,750,000 USD
Aug. 19, 2014 Aug. 18, 2014 S Sale

Avalon Ventures VIII LP

Major owner
50,001 -3.3%
16.00
800,016 USD
50,001 -3.3% 16.00 800,016 USD
Aug. 19, 2014 Aug. 18, 2014 B Purchase

Khuong Chau Quang

Non-Executive Director Major owner
171,875 +8.2%
16.00
2,750,000 USD
171,875 +8.2% 16.00 2,750,000 USD
Aug. 19, 2014 Aug. 18, 2014 S Sale

MCKEARN JOHN P

Non-Executive Director
5,340 -2.4%
8.79
46,939 USD
5,340 -2.4% 8.79 46,939 USD
Aug. 19, 2014 Aug. 18, 2014 S Sale

MCKEARN JOHN P

Non-Executive Director
19,660 -2.4%
8.79
172,811 USD
19,660 -2.4% 8.79 172,811 USD
Aug. 19, 2014 Aug. 18, 2014 B Purchase

Lichter Jay

Non-Executive Director Major owner
109,375 +15.5%
16.00
1,750,000 USD
109,375 +15.5% 16.00 1,750,000 USD
Aug. 19, 2014 Aug. 18, 2014 S Sale

Lichter Jay

Non-Executive Director Major owner
50,001 -3.3%
16.00
800,016 USD
50,001 -3.3% 16.00 800,016 USD
Aug. 19, 2014 Aug. 18, 2014 B Purchase

ORBIMED ADVISORS LLC

Major owner
171,875 +8.2%
16.00
2,750,000 USD
171,875 +8.2% 16.00 2,750,000 USD

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