United States Biotechnology & Medical Research

Milestone Pharmaceuticals Inc (MIST)

Track

Insider trading activity at Milestone Pharmaceuticals Inc. has consisted exclusively of sales by executives, including the CEO and other senior officers. The most recent transactions occurred on April 16, 2026, involving multiple sales and planned divestments by Joseph Oliveto. No insider buying has been reported during the observed period.
Ticker: MIST Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Milestone Pharmaceuticals Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Top insiders
Trades
Sale 16 Apr 2026
Value US$520,932.28 | Price 40.06 | Shares 42,079 (+1.3%)
Sale 16 Apr 2026
Value US$2,755,093.53 | Price 345.29 | Shares 61,649 (+32.3%)
Sale 16 Apr 2026
Value US$37,479.84 | Price 2.26 | Shares 16,584 (-5.7%)
Sale 16 Apr 2026
Value US$5,321.80 | Price 2.26 | Shares 2,360 (-0.8%)
Sale 16 Apr 2026
Value US$26,001.00 | Price 2.25 | Shares 11,556 (-3.8%)
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-04-20 2026-04-16 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
42,079 +1.3%
40.06
US$520,932 		42,079 +1.3% 40.06 US$520,932
2026-04-20 2026-04-16 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
61,649 +32.3%
345.29
US$2,755,094 		61,649 +32.3% 345.29 US$2,755,094
2026-04-20 2026-04-16 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
40,988 +19.4%
239.94
US$3,715,194 		40,988 +19.4% 239.94 US$3,715,194
2026-04-20 2026-04-16 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
2,360 -0.8%
2.26
US$5,322 		2,360 -0.8% 2.26 US$5,322
2026-04-20 2026-04-16 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
11,556 -3.8%
2.25
US$26,001 		11,556 -3.8% 2.25 US$26,001
2026-04-20 2026-04-16 PlS Planned sale
3.5
Oliveto Joseph

President and CEO

Executive Director
36,500 -7.6%
2.26
US$82,490 		36,500 -7.6% 2.26 US$82,490
2026-04-16 2026-04-16 PrS Proposed sale
3.5
JOSEPH OLIVETO

Director; Officer

Executive Director
36,500
2.20
US$80,300 		36,500 2.20 US$80,300
2026-01-28 2026-01-26 S Sale
3.5
Nelson Jeffrey Edward

Chief Operating Officer

Officer
12,245 -19.7%
1.93
US$23,633 		12,245 -19.7% 1.93 US$23,633
2026-01-28 2026-01-26 S Sale
2.0
Bharucha David

Chief Medical Officer

Officer
12,245 -9.8%
1.93
US$23,633 		12,245 -9.8% 1.93 US$23,633
2026-01-28 2026-01-26 S Sale
3.5
Hasija Amit

CFO & EVP of Corp. Development

Officer
12,245 -10.9%
1.93
US$23,633 		12,245 -10.9% 1.93 US$23,633
2026-01-28 2026-01-26 S Sale
3.5
Oliveto Joseph

President and CEO

Executive Director
34,523 -6.7%
1.93
US$66,629 		34,523 -6.7% 1.93 US$66,629
2026-01-28 2026-01-26 S Sale
3.5
Muller Lorenz

Chief Commercial Officer

Officer
11,180 -5.2%
1.93
US$21,577 		11,180 -5.2% 1.93 US$21,577
2026-01-09 2026-01-08 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
448 -0.1%
2.27
CA$1,015 		448 -0.1% 2.27 CA$1,015
2026-01-09 2026-01-08 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
13,352 -4.2%
2.26
CA$30,176 		13,352 -4.2% 2.26 CA$30,176
2026-01-09 2026-01-08 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
1,449 -0.5%
2.26
CA$3,267 		1,449 -0.5% 2.26 CA$3,267
2026-01-09 2026-01-08 S Sale
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
27,751 -8.0%
2.25
CA$62,440 		27,751 -8.0% 2.25 CA$62,440
2026-01-09 2026-01-08 PlS Planned sale
3.5
Oliveto Joseph

President and CEO

Executive Director
43,000 -12.4%
2.25
US$96,750 		43,000 -12.4% 2.25 US$96,750
2026-01-08 2026-01-08 PrS Proposed sale
3.5
JOSEPH OLIVETO

Director; Officer

Executive Director
79,500
2.15
US$170,925 		79,500 2.15 US$170,925
2026-01-09 2026-01-07 PlS Planned sale
3.5
Oliveto Joseph

President and CEO

Executive Director
500 -0.1%
2.25
US$1,125 		500 -0.1% 2.25 US$1,125
2026-01-07 2026-01-07 PrS Proposed sale
3.5
JOSEPH OLIVETO

Officer

Officer
500
2.05
US$1,025 		500 2.05 US$1,025
2026-01-28 2025-12-15 S Sale
3.5
Nelson Jeffrey Edward

Chief Operating Officer

Officer
58,007 -58.0%
2.32
US$134,576 		58,007 -58.0% 2.32 US$134,576
2026-01-28 2025-12-15 S Sale
2.0
Bharucha David

Chief Medical Officer

Officer
58,007 -35.5%
2.32
US$134,576 		58,007 -35.5% 2.32 US$134,576
2026-01-28 2025-12-15 S Sale
3.5
Hasija Amit

CFO & EVP of Corp. Development

Officer
58,007 -38.7%
2.32
US$134,576 		58,007 -38.7% 2.32 US$134,576
2026-01-28 2025-12-15 S Sale
3.5
Oliveto Joseph

President and CEO

Executive Director
133,054 -22.8%
2.32
US$308,685 		133,054 -22.8% 2.32 US$308,685
2026-01-28 2025-12-15 S Sale
3.5
Muller Lorenz

Chief Commercial Officer

Officer
53,566 -21.4%
2.32
US$124,273 		53,566 -21.4% 2.32 US$124,273
2025-07-15 2025-07-11 B Purchase
2.5
Wills, Robert James

Director of Issuer

Non-Executive Director
50,000 +333.3%
1.50
US$75,000 		50,000 +333.3% 1.50 US$75,000
2025-07-15 2025-07-11 B Purchase
3.1
Papa, Joseph

Director of Issuer

Non-Executive Director
100,000
1.50
US$150,000 		100,000 1.50 US$150,000
2025-07-15 2025-07-11 B Purchase
3.6
Oliveto, Joseph Gerard

Director of Issuer, Senior Officer of Issuer

Executive Director
66,666 +23.8%
1.50
US$99,999 		66,666 +23.8% 1.50 US$99,999
2025-07-15 2025-07-11 B Purchase
3.0
Muller, Lorenz Andrew

Senior Officer of Issuer

Officer
66,666 +50.0%
1.50
US$99,999 		66,666 +50.0% 1.50 US$99,999
2025-07-15 2025-07-11 B Purchase
3.1
Hasija, Amit

Senior Officer of Issuer

Officer
50,000
1.50
US$75,000 		50,000 1.50 US$75,000
2025-07-15 2025-07-11 B Purchase
3.1
Bharucha, David

Senior Officer of Issuer

Officer
53,333 +533.3%
1.50
US$80,000 		53,333 +533.3% 1.50 US$80,000
2023-04-28 2023-04-27 B Purchase
3.0
Muller, Lorenz Andrew

Senior Officer of Issuer

Officer
5,500 +4.3%
3.80
US$20,892 		5,500 +4.3% 3.80 US$20,892
2023-04-28 2023-04-27 B Purchase
3.0
Muller, Lorenz Andrew

Senior Officer of Issuer

Officer
7,000 +5.8%
3.79
US$26,498 		7,000 +5.8% 3.79 US$26,498
2023-04-28 2023-04-27 B Purchase
3.0
Muller, Lorenz Andrew

Senior Officer of Issuer

Officer
5,500 +4.8%
3.73
US$20,514 		5,500 +4.8% 3.73 US$20,514
2023-04-28 2023-04-27 B Purchase
3.0
Muller, Lorenz Andrew

Senior Officer of Issuer

Officer
7,000 +6.5%
3.72
US$26,024 		7,000 +6.5% 3.72 US$26,024
2022-12-05 2022-12-05 B Purchase
2.0
Bharucha David

Chief Medical Officer

Officer
7,000 +233.3%
4.69
US$32,830 		7,000 +233.3% 4.69 US$32,830
2022-12-05 2022-12-01 B Purchase
2.0
Bharucha David

Chief Medical Officer

Officer
3,000 +inf%
4.86
US$14,580 		3,000 +inf% 4.86 US$14,580
2022-10-21 2022-10-21 B Purchase
0.9
Liebert, Debra Kay

Director of Issuer

Non-Executive Director
4,000
5.26
US$21,040 		4,000 5.26 US$21,040
2022-10-21 2022-10-21 B Purchase
0.9
Liebert Debra K.
Non-Executive Director
4,000 +inf%
5.26
US$21,040 		4,000 +inf% 5.26 US$21,040
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
200 +2.0%
5.07
US$1,013 		200 +2.0% 5.07 US$1,013
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
300 +3.2%
5.17
US$1,551 		300 +3.2% 5.17 US$1,551
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
368 +4.0%
5.10
US$1,877 		368 +4.0% 5.10 US$1,877
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
300 +3.4%
5.12
US$1,536 		300 +3.4% 5.12 US$1,536
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
100 +1.1%
5.16
US$516 		100 +1.1% 5.16 US$516
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
700 +8.7%
5.11
US$3,577 		700 +8.7% 5.11 US$3,577
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
1,732 +27.5%
5.20
US$9,006 		1,732 +27.5% 5.20 US$9,006
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
700 +12.5%
5.18
US$3,626 		700 +12.5% 5.18 US$3,626
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak, Richard C.

Director of Issuer

Non-Executive Director
5,600
5.24
US$29,344 		5,600 5.24 US$29,344
2022-10-21 2022-10-20 B Purchase
0.9
Liebert, Debra Kay

Director of Issuer

Non-Executive Director
600 +6.4%
5.24
US$3,144 		600 +6.4% 5.24 US$3,144
2022-10-21 2022-10-20 B Purchase
0.9
Liebert, Debra Kay

Director of Issuer

Non-Executive Director
400 +4.4%
5.27
US$2,108 		400 +4.4% 5.27 US$2,108
2022-10-21 2022-10-20 B Purchase
0.9
Liebert, Debra Kay

Director of Issuer

Non-Executive Director
45 +0.5%
5.26
US$237 		45 +0.5% 5.26 US$237
2022-10-21 2022-10-20 B Purchase
0.9
Liebert, Debra Kay

Director of Issuer

Non-Executive Director
2,655 +42.1%
5.28
US$14,018 		2,655 +42.1% 5.28 US$14,018
2022-10-21 2022-10-20 B Purchase
0.9
Liebert, Debra Kay

Director of Issuer

Non-Executive Director
105 +1.7%
5.29
US$555 		105 +1.7% 5.29 US$555
2022-10-21 2022-10-20 B Purchase
0.9
Liebert, Debra Kay

Director of Issuer

Non-Executive Director
6,195
5.30
US$32,834 		6,195 5.30 US$32,834
2022-10-21 2022-10-20 B Purchase
0.6
Pasternak Richard C
Non-Executive Director
10,000 +inf%
5.20
US$52,000 		10,000 +inf% 5.20 US$52,000
2022-10-21 2022-10-20 B Purchase
0.9
Liebert Debra K.
Non-Executive Director
10,000 +inf%
5.29
US$52,900 		10,000 +inf% 5.29 US$52,900
2022-10-21 2022-10-19 B Purchase
0.6
Tomsicek, Michael John

Director of Issuer

Non-Executive Director
15,000
5.32
US$79,857 		15,000 5.32 US$79,857
2022-10-21 2022-10-19 B Purchase
0.6
TOMSICEK MICHAEL JOHN
Non-Executive Director
15,000 +inf%
5.32
US$79,800 		15,000 +inf% 5.32 US$79,800
2022-10-21 2022-10-19 B Purchase
1.8
Wills Robert James
Non-Executive Director
15,000 +inf%
4.93
US$73,950 		15,000 +inf% 4.93 US$73,950
2022-10-19 2022-10-19 B Purchase
2.5
Wills, Robert James

Director of Issuer

Non-Executive Director
15,000
4.93
US$73,918 		15,000 4.93 US$73,918
2022-09-09 2022-09-07 S Sale
2.7
RTW INVESTMENTS, LP
Large shareholder
1,557,346 -26.5%
8.71
US$13,564,484 		1,557,346 -26.5% 8.71 US$13,564,484
2022-09-09 2022-09-07 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
1,557,346 +56.5%
8.71
US$13,564,484 		1,557,346 +56.5% 8.71 US$13,564,484
2022-06-01 2022-05-31 B Purchase
3.2
TRUEX PAUL F
Non-Executive Director
5,000 +6.5%
5.60
US$28,000 		5,000 +6.5% 5.60 US$28,000
2020-07-30 2020-07-29 S Sale
3.8
FONDS DE SOLIDARITE DES TRAVAILLEURS DU QUEBEC
Large shareholder
500,000 -18.1%
8.32
US$4,160,000 		500,000 -18.1% 8.32 US$4,160,000
2020-07-30 2020-07-28 S Sale
3.8
FONDS DE SOLIDARITE DES TRAVAILLEURS DU QUEBEC
Large shareholder
19,863 -0.7%
8.10
US$160,890 		19,863 -0.7% 8.10 US$160,890
2020-03-19 2020-03-19 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
5,870 +0.1%
10.87
US$63,804 		5,870 +0.1% 10.87 US$63,804
2020-03-19 2020-03-18 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
2,705 +0.1%
10.36
US$28,029 		2,705 +0.1% 10.36 US$28,029
2020-03-19 2020-03-02 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
78,263 +1.9%
18.95
US$1,483,084 		78,263 +1.9% 18.95 US$1,483,084
2020-01-13 2020-01-13 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
270,000 +6.8%
16.25
US$4,387,500 		270,000 +6.8% 16.25 US$4,387,500
2020-01-02 2019-12-31 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
21,438 +0.5%
15.50
US$332,340 		21,438 +0.5% 15.50 US$332,340
2020-01-02 2019-12-30 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
1,333 +0.0%
15.48
US$20,638 		1,333 +0.0% 15.48 US$20,638
2019-11-27 2019-11-25 S Sale
2.3
Novo Holdings A/S

SEE REMARKS

Large shareholder
240,000 -9.0%
16.00
US$3,840,000 		240,000 -9.0% 16.00 US$3,840,000
2019-11-22 2019-11-20 B Purchase RTW INVESTMENTS, LP Large shareholder
400,000 +11.3%
16.00
US$6,400,000 		400,000 +11.3% 16.00 US$6,400,000
2019-10-15 2019-10-15 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
1,100 +0.0%
18.00
US$19,800 		1,100 +0.0% 18.00 US$19,800
2019-10-15 2019-10-11 B Purchase
2.7
RTW INVESTMENTS, LP
Large shareholder
4,208 +0.1%
17.30
US$72,791 		4,208 +0.1% 17.30 US$72,791
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