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United States Biotechnology & Medical Research

Gyre Therapeutics Inc (GYRE)

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Over the last 90 days, Gyre Therapeutics Inc. has seen significant insider selling, with a net value of approximately -$1.39 million. The Chief Operating Officer, Ye Weiguo, has been the primary seller, offloading shares across multiple transactions. There have been no insider purchases recorded during this period. The stock has experienced a 12.9% decline in the past 90 days.
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Ticker: GYRE Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
Ye Weiguo
Chief Operating Officer
2 sales — total 200,000 USD
Sale 18 Jun 2026
Value US$979,323.08 | Price 312.53 | Shares 36,345
Sale 18 Jun 2026
Value US$707,623.85 | Price 409.94 | Shares 18,685
Sale 11 Jun 2026
Value US$2,840,793.81 | Price 247.19 | Shares 54,278
Sale 10 Jun 2026
Value US$100,000.00 | Price 6.24 | Shares 1,000
Sale 10 Jun 2026
Value US$100,000.00 | Price 6.24 | Shares 1,000
Sale 10 Jun 2026
Value US$100,000.00 | Price 6.21 | Shares 1,000
Sale 10 Jun 2026
Value US$100,000.00 | Price 6.21 | Shares 1,000
Sale 10 Jun 2026
Value US$100,000.00 | Price 6.21 | Shares 1,000
Sale 9 Jun 2026
Value US$100,000.00 | Price 6.15 | Shares 1,000
Sale 9 Jun 2026
Value US$100,000.00 | Price 6.15 | Shares 1,000
Sale 9 Jun 2026
Value US$100,000.00 | Price 6.14 | Shares 1,000
Sale 9 Jun 2026
Value US$100,000.00 | Price 6.14 | Shares 1,000
Sale 9 Jun 2026
Value US$100,000.00 | Price 6.14 | Shares 1,000
Sale 5 Jun 2026
Value US$100,000.00 | Price 6.40 | Shares 1,000
Sale 4 Jun 2026
Value US$100,000.00 | Price 6.13 | Shares 1,000
Sale 26 May 2026
Value US$24,400.40 | Price 6.10 | Shares 4,000
Sale 22 May 2026
Value US$21,280.00 | Price 6.08 | Shares 3,500
Sale 21 May 2026
Value US$78,843.00 | Price 6.15 | Shares 12,820
Sale 20 May 2026
Value US$57,810.00 | Price 6.15 | Shares 9,400
Sale 19 May 2026
Value US$58,094.40 | Price 6.37 | Shares 9,120
Sale 18 May 2026
Value US$1,324.00 | Price 6.62 | Shares 200
Sale 15 May 2026
Value US$87,115.00 | Price 6.65 | Shares 13,100
Sale 15 May 2026
Value US$87,115.00 | Price 6.65 | Shares 13,100
Sale 14 May 2026
Value US$107,657.80 | Price 6.91 | Shares 15,580
Sale 14 May 2026
Value US$107,657.80 | Price 6.91 | Shares 15,580
Proposed sale 13 May 2026
Value US$2,121,000.00 | Price 7.07 | Shares 300,000
Planned sale 6 May 2026
Value US$81,493.44 | Price 8.04 | Shares 10,136
Planned sale 5 May 2026
Value US$1,433.79 | Price 8.01 | Shares 179
Proposed sale 15 Nov 2025
Value US$4,570,320.00 | Price 8.34 | Shares 548,000
Planned sale 28 May 2025
Value US$5,619.06 | Price 10.07 | Shares 558
Planned sale 27 May 2025
Value US$20,560.00 | Price 10.28 | Shares 2,000
Planned sale 23 May 2025
Value US$1,863.68 | Price 10.24 | Shares 182
Planned sale 22 May 2025
Value US$21,940.00 | Price 10.97 | Shares 2,000
Planned sale 21 May 2025
Value US$21,660.00 | Price 10.83 | Shares 2,000
Planned sale 20 May 2025
Value US$22,500.00 | Price 11.25 | Shares 2,000
Planned sale 19 May 2025
Value US$22,220.00 | Price 11.11 | Shares 2,000
Planned sale 16 May 2025
Value US$22,620.00 | Price 11.31 | Shares 2,000
Planned sale 15 May 2025
Value US$21,360.00 | Price 10.68 | Shares 2,000
Planned sale 14 May 2025
Value US$226.00 | Price 11.30 | Shares 20
Planned sale 13 May 2025
Value US$22,740.00 | Price 11.37 | Shares 2,000
Planned sale 12 May 2025
Value US$21,120.00 | Price 10.56 | Shares 2,000
Planned sale 21 Mar 2025
Value US$1,740.00 | Price 10.00 | Shares 174
Planned sale 20 Mar 2025
Value US$20,180.00 | Price 10.09 | Shares 2,000
Planned sale 19 Mar 2025
Value US$20,260.00 | Price 10.13 | Shares 2,000
Planned sale 18 Mar 2025
Value US$2,478.08 | Price 10.24 | Shares 242
Planned sale 17 Mar 2025
Value US$24,180.00 | Price 12.09 | Shares 2,000
Planned sale 14 Mar 2025
Value US$24,620.00 | Price 12.31 | Shares 2,000
Planned sale 13 Mar 2025
Value US$23,600.00 | Price 11.80 | Shares 2,000
Planned sale 12 Mar 2025
Value US$23,480.00 | Price 11.74 | Shares 2,000
Planned sale 11 Mar 2025
Value US$22,800.00 | Price 11.40 | Shares 2,000
Planned sale 10 Mar 2025
Value US$20,280.00 | Price 10.14 | Shares 2,000
Planned sale 7 Mar 2025
Value US$19,307.78 | Price 10.13 | Shares 1,906
Planned sale 7 Mar 2025
Value US$497.74 | Price 12.14 | Shares 41
Planned sale 7 Mar 2025
Value US$690.59 | Price 13.03 | Shares 53
Planned sale 6 Mar 2025
Value US$21,600.00 | Price 10.80 | Shares 2,000
Planned sale 5 Mar 2025
Value US$21,960.00 | Price 10.98 | Shares 2,000
Planned sale 4 Mar 2025
Value US$21,720.00 | Price 10.86 | Shares 2,000
Planned sale 3 Mar 2025
Value US$22,460.00 | Price 11.23 | Shares 2,000
Planned sale 28 Feb 2025
Value US$22,820.00 | Price 11.41 | Shares 2,000
Planned sale 27 Feb 2025
Value US$22,660.00 | Price 11.33 | Shares 2,000
Planned sale 26 Feb 2025
Value US$23,260.00 | Price 11.63 | Shares 2,000
Planned sale 25 Feb 2025
Value US$22,740.00 | Price 11.37 | Shares 2,000
Planned sale 24 Feb 2025
Value US$2,154.24 | Price 11.52 | Shares 187
Planned sale 24 Feb 2025
Value US$19,217.80 | Price 10.60 | Shares 1,813
Planned sale 21 Feb 2025
Value US$2,293.20 | Price 12.60 | Shares 182
Planned sale 21 Feb 2025
Value US$21,525.12 | Price 11.84 | Shares 1,818
Planned sale 20 Feb 2025
Value US$24,800.00 | Price 12.40 | Shares 2,000
Planned sale 19 Feb 2025
Value US$24,580.00 | Price 12.29 | Shares 2,000
Planned sale 18 Feb 2025
Value US$24,980.00 | Price 12.49 | Shares 2,000
Planned sale 14 Feb 2025
Value US$23,880.00 | Price 11.94 | Shares 2,000
Planned sale 13 Feb 2025
Value US$23,380.00 | Price 11.69 | Shares 2,000
Planned sale 12 Feb 2025
Value US$22,980.00 | Price 11.49 | Shares 2,000
Planned sale 11 Feb 2025
Value US$21,634.56 | Price 11.52 | Shares 1,878
Planned sale 10 Feb 2025
Value US$23,800.00 | Price 11.90 | Shares 2,000
Planned sale 7 Feb 2025
Value US$24,320.00 | Price 12.16 | Shares 2,000
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-06-22 2026-06-18 S Sale
Ye Weiguo

Chief Operating Officer

Officer
36,345 +32.0%
312.53
US$979,323 		36,345 +32.0% 312.53 US$979,323
2026-06-22 2026-06-18 S Sale
Ye Weiguo

Chief Operating Officer

Officer
18,685 -39.8%
409.94
US$707,624 		18,685 -39.8% 409.94 US$707,624
2026-06-15 2026-06-11 S Sale
Ye Weiguo

Chief Operating Officer

Officer
54,278 +40.3%
247.19
US$2,840,794 		54,278 +40.3% 247.19 US$2,840,794
2026-06-22 2026-06-10 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -0.7%
6.24
US$100,000 		1,000 -0.7% 6.24 US$100,000
2026-06-22 2026-06-10 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -0.7%
6.24
US$100,000 		1,000 -0.7% 6.24 US$100,000
2026-06-11 2026-06-10 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -0.9%
6.21
US$100,000 		1,000 -0.9% 6.21 US$100,000
2026-06-11 2026-06-10 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -0.9%
6.21
US$100,000 		1,000 -0.9% 6.21 US$100,000
2026-06-11 2026-06-10 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -0.9%
6.21
US$100,000 		1,000 -0.9% 6.21 US$100,000
2026-06-22 2026-06-09 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -0.4%
6.15
US$100,000 		1,000 -0.4% 6.15 US$100,000
2026-06-22 2026-06-09 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -0.4%
6.15
US$100,000 		1,000 -0.4% 6.15 US$100,000
2026-06-11 2026-06-09 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -2.0%
6.14
US$100,000 		1,000 -2.0% 6.14 US$100,000
2026-06-11 2026-06-09 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -2.0%
6.14
US$100,000 		1,000 -2.0% 6.14 US$100,000
2026-06-11 2026-06-09 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -2.0%
6.14
US$100,000 		1,000 -2.0% 6.14 US$100,000
2026-06-08 2026-06-05 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -2.2%
6.40
US$100,000 		1,000 -2.2% 6.40 US$100,000
2026-06-08 2026-06-04 S Sale
Ye Weiguo

Chief Operating Officer

Officer
1,000 -2.7%
6.13
US$100,000 		1,000 -2.7% 6.13 US$100,000
2026-05-27 2026-05-26 S Sale
Ye Weiguo

Chief Operating Officer

Officer
4,000 -0.6%
6.10
US$24,400 		4,000 -0.6% 6.10 US$24,400
2026-05-27 2026-05-22 S Sale
Ye Weiguo

Chief Operating Officer

Officer
3,500 -0.5%
6.08
US$21,280 		3,500 -0.5% 6.08 US$21,280
2026-05-22 2026-05-21 S Sale
Ye Weiguo

Chief Operating Officer

Officer
12,820 -1.8%
6.15
US$78,843 		12,820 -1.8% 6.15 US$78,843
2026-05-22 2026-05-20 S Sale
Ye Weiguo

Chief Operating Officer

Officer
9,400 -1.3%
6.15
US$57,810 		9,400 -1.3% 6.15 US$57,810
2026-05-20 2026-05-19 S Sale
Ye Weiguo

Chief Operating Officer

Officer
9,120 -1.3%
6.37
US$58,094 		9,120 -1.3% 6.37 US$58,094
2026-05-20 2026-05-18 S Sale
Ye Weiguo

Chief Operating Officer

Officer
200 -0.0%
6.62
US$1,324 		200 -0.0% 6.62 US$1,324
2026-05-18 2026-05-15 S Sale
Ye Weiguo

Chief Operating Officer

Officer
13,100 -1.8%
6.65
US$87,115 		13,100 -1.8% 6.65 US$87,115
2026-05-18 2026-05-15 S Sale
Ye Weiguo

Chief Operating Officer

Officer
13,100 -1.8%
6.65
US$87,115 		13,100 -1.8% 6.65 US$87,115
2026-05-18 2026-05-14 S Sale
Ye Weiguo

Chief Operating Officer

Officer
15,580 -2.2%
6.91
US$107,658 		15,580 -2.2% 6.91 US$107,658
2026-05-18 2026-05-14 S Sale
Ye Weiguo

Chief Operating Officer

Officer
15,580 -2.2%
6.91
US$107,658 		15,580 -2.2% 6.91 US$107,658
2026-05-11 2026-05-13 PrS Proposed sale
Ye Weiguo

Officer

Officer
300,000
7.07
US$2,121,000 		300,000 7.07 US$2,121,000
2026-05-07 2026-05-06 PlS Planned sale
Luo Ying

Chief Executive Officer

Executive Director
10,136 -0.4%
8.04
US$81,493 		10,136 -0.4% 8.04 US$81,493
2026-05-07 2026-05-05 PlS Planned sale
Luo Ying

Chief Executive Officer

Executive Director
179 -0.0%
8.01
US$1,434 		179 -0.0% 8.01 US$1,434
2025-11-13 2025-11-15 PrS Proposed sale
Ye Weiguo

Officer

Officer
548,000
8.34
US$4,570,320 		548,000 8.34 US$4,570,320
2025-05-29 2025-05-28 PlS Planned sale
Ma Songjiang

President

Executive Director
558 -0.0%
10.07
US$5,619 		558 -0.0% 10.07 US$5,619
2025-05-29 2025-05-27 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.28
US$20,560 		2,000 -0.1% 10.28 US$20,560
2025-05-27 2025-05-23 PlS Planned sale
Ma Songjiang

President

Executive Director
182 -0.0%
10.24
US$1,864 		182 -0.0% 10.24 US$1,864
2025-05-27 2025-05-22 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.97
US$21,940 		2,000 -0.1% 10.97 US$21,940
2025-05-22 2025-05-21 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.83
US$21,660 		2,000 -0.1% 10.83 US$21,660
2025-05-22 2025-05-20 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.25
US$22,500 		2,000 -0.1% 11.25 US$22,500
2025-05-20 2025-05-19 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.11
US$22,220 		2,000 -0.1% 11.11 US$22,220
2025-05-20 2025-05-16 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.31
US$22,620 		2,000 -0.1% 11.31 US$22,620
2025-05-16 2025-05-15 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.68
US$21,360 		2,000 -0.1% 10.68 US$21,360
2025-05-16 2025-05-14 PlS Planned sale
Ma Songjiang

President

Executive Director
20 -0.0%
11.30
US$226 		20 -0.0% 11.30 US$226
2025-05-14 2025-05-13 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.37
US$22,740 		2,000 -0.1% 11.37 US$22,740
2025-05-14 2025-05-12 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.56
US$21,120 		2,000 -0.1% 10.56 US$21,120
2025-03-25 2025-03-21 PlS Planned sale
Ma Songjiang

President

Executive Director
174 -0.0%
10.00
US$1,740 		174 -0.0% 10.00 US$1,740
2025-03-21 2025-03-20 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.09
US$20,180 		2,000 -0.1% 10.09 US$20,180
2025-03-21 2025-03-19 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.13
US$20,260 		2,000 -0.1% 10.13 US$20,260
2025-03-19 2025-03-18 PlS Planned sale
Ma Songjiang

President

Executive Director
242 -0.0%
10.24
US$2,478 		242 -0.0% 10.24 US$2,478
2025-03-19 2025-03-17 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
12.09
US$24,180 		2,000 -0.1% 12.09 US$24,180
2025-03-17 2025-03-14 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
12.31
US$24,620 		2,000 -0.1% 12.31 US$24,620
2025-03-17 2025-03-13 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.80
US$23,600 		2,000 -0.1% 11.80 US$23,600
2025-03-13 2025-03-12 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.74
US$23,480 		2,000 -0.1% 11.74 US$23,480
2025-03-13 2025-03-11 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.40
US$22,800 		2,000 -0.1% 11.40 US$22,800
2025-03-11 2025-03-10 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.14
US$20,280 		2,000 -0.1% 10.14 US$20,280
2025-03-11 2025-03-07 PlS Planned sale
Ma Songjiang

President

Executive Director
1,906 -0.1%
10.13
US$19,308 		1,906 -0.1% 10.13 US$19,308
2025-03-11 2025-03-07 PlS Planned sale
Ma Songjiang

President

Executive Director
41 -0.0%
12.14
US$498 		41 -0.0% 12.14 US$498
2025-03-11 2025-03-07 PlS Planned sale
Ma Songjiang

President

Executive Director
53 -0.0%
13.03
US$691 		53 -0.0% 13.03 US$691
2025-03-07 2025-03-06 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.80
US$21,600 		2,000 -0.1% 10.80 US$21,600
2025-03-07 2025-03-05 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.98
US$21,960 		2,000 -0.1% 10.98 US$21,960
2025-03-05 2025-03-04 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
10.86
US$21,720 		2,000 -0.1% 10.86 US$21,720
2025-03-05 2025-03-03 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.23
US$22,460 		2,000 -0.1% 11.23 US$22,460
2025-03-03 2025-02-28 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.41
US$22,820 		2,000 -0.1% 11.41 US$22,820
2025-03-03 2025-02-27 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.33
US$22,660 		2,000 -0.1% 11.33 US$22,660
2025-02-27 2025-02-26 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.63
US$23,260 		2,000 -0.1% 11.63 US$23,260
2025-02-27 2025-02-25 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.37
US$22,740 		2,000 -0.1% 11.37 US$22,740
2025-02-25 2025-02-24 PlS Planned sale
Ma Songjiang

President

Executive Director
187 -0.0%
11.52
US$2,154 		187 -0.0% 11.52 US$2,154
2025-02-25 2025-02-24 PlS Planned sale
Ma Songjiang

President

Executive Director
1,813 -0.1%
10.60
US$19,218 		1,813 -0.1% 10.60 US$19,218
2025-02-25 2025-02-21 PlS Planned sale
Ma Songjiang

President

Executive Director
182 -0.0%
12.60
US$2,293 		182 -0.0% 12.60 US$2,293
2025-02-25 2025-02-21 PlS Planned sale
Ma Songjiang

President

Executive Director
1,818 -0.1%
11.84
US$21,525 		1,818 -0.1% 11.84 US$21,525
2025-02-21 2025-02-20 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
12.40
US$24,800 		2,000 -0.1% 12.40 US$24,800
2025-02-21 2025-02-19 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
12.29
US$24,580 		2,000 -0.1% 12.29 US$24,580
2025-02-19 2025-02-18 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
12.49
US$24,980 		2,000 -0.1% 12.49 US$24,980
2025-02-19 2025-02-14 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.94
US$23,880 		2,000 -0.1% 11.94 US$23,880
2025-02-14 2025-02-13 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.69
US$23,380 		2,000 -0.1% 11.69 US$23,380
2025-02-14 2025-02-12 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.49
US$22,980 		2,000 -0.1% 11.49 US$22,980
2025-02-12 2025-02-11 PlS Planned sale
Ma Songjiang

President

Executive Director
1,878 -0.1%
11.52
US$21,635 		1,878 -0.1% 11.52 US$21,635
2025-02-12 2025-02-10 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
11.90
US$23,800 		2,000 -0.1% 11.90 US$23,800
2025-02-11 2025-02-07 PlS Planned sale
Ma Songjiang

President

Executive Director
2,000 -0.1%
12.16
US$24,320 		2,000 -0.1% 12.16 US$24,320
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