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United States Biotechnology & Medical Research

Plus Therapeutics Inc (PSTV)

Track

The most recent insider trading activity occurred on November 4, 2025, with the Chief Financial Officer purchasing shares. Prior to this, transactions included multiple buy orders from various insiders in September and May 2024, and a proposed sale by a Director in May 2025. The majority of recent transactions have been purchases.
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Ticker: PSTV Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
Sims Andrew John Hugh MacIntyre
Chief Financial Officer
1 purchase — total 10,200 USD
Buy 4 Nov 2025
Value US$3,980,364.51 | Price 353.15 | Shares 25,689
Buy 22 Aug 2025
Value US$3,929,309.70 | Price 351.22 | Shares 67,681
Proposed sale 15 May 2025
Value US$20,276.30 | Price 0.55 | Shares 36,666
Buy 13 Sep 2024
Value US$5,996.00 | Price 1.50 | Shares 4,000
Buy 12 Sep 2024
Value US$8,511.78 | Price 1.35 | Shares 6,285
Buy 11 Sep 2024
Value US$6,681.00 | Price 1.34 | Shares 5,000
Buy 11 Sep 2024
Value US$16,875.00 | Price 1.35 | Shares 12,500
Buy 10 Sep 2024
Value US$5,204.46 | Price 1.27 | Shares 4,098
Buy 10 Sep 2024
Value US$9,839.20 | Price 1.23 | Shares 8,000
Buy 8 May 2024
Value US$8,500.68 | Price 2.04 | Shares 4,167
Buy 8 May 2024
Value US$8,500.68 | Price 2.04 | Shares 4,167
Buy 8 May 2024
Value US$20,000.16 | Price 2.04 | Shares 9,804
Buy 8 May 2024
Value US$25,000.20 | Price 2.04 | Shares 12,255
Buy 8 May 2024
Value US$25,000.20 | Price 2.04 | Shares 12,255
Buy 8 May 2024
Value US$10,000.08 | Price 2.04 | Shares 4,902
Buy 8 May 2024
Value US$10,000.08 | Price 2.04 | Shares 4,902
Sale 20 Nov 2023
Value US$4,052.66 | Price 1.96 | Shares 2,068
Buy 16 Nov 2023
Value US$1,950.00 | Price 1.95 | Shares 1,000
Buy 15 Nov 2023
Value US$1,770.00 | Price 1.77 | Shares 1,000
Buy 13 Nov 2023
Value US$5,720.00 | Price 1.43 | Shares 4,000
Buy 10 Nov 2023
Value US$2,900.00 | Price 1.45 | Shares 2,000
Buy 9 Nov 2023
Value US$6,676.41 | Price 1.59 | Shares 4,199
Buy 8 Nov 2023
Value US$8,250.00 | Price 1.65 | Shares 5,000
Buy 7 Nov 2023
Value US$9,840.00 | Price 1.64 | Shares 6,000
Buy 6 Nov 2023
Value US$2,092.50 | Price 1.50 | Shares 1,395
Buy 13 Sep 2023
Value US$10,021.67 | Price 1.43 | Shares 6,993
Buy 11 Sep 2023
Value US$34,062.00 | Price 1.70 | Shares 20,000
Buy 6 Jun 2023
Value US$3,980.00 | Price 3.98 | Shares 1,000
Buy 3 May 2023
Value US$9,101.50 | Price 3.64 | Shares 2,500
Buy 3 Mar 2023
Value US$1,000.00 | Price 1,000.00 | Shares 1
Sale 30 Dec 2022
Value US$472.05 | Price 0.31 | Shares 1,500
Buy 15 Jun 2022
Value US$3,240.00 | Price 0.65 | Shares 5,000
Buy 2 Jun 2022
Value US$8,589.00 | Price 0.57 | Shares 15,000
Buy 17 May 2022
Value US$16,500.00 | Price 0.55 | Shares 30,000
Buy 26 Apr 2022
Value US$1,710.25 | Price 0.68 | Shares 2,500
Buy 26 Apr 2022
Value US$3,450.00 | Price 0.69 | Shares 5,000
Buy 26 Apr 2022
Value US$2,016.00 | Price 0.67 | Shares 3,000
Buy 1 Mar 2022
Value US$2,199.80 | Price 1.10 | Shares 2,000
Buy 2 Nov 2021
Value US$1,864.30 | Price 1.86 | Shares 1,000
Buy 27 Oct 2021
Value US$21,500.00 | Price 1.72 | Shares 12,500
Buy 26 Oct 2021
Value US$4,149.75 | Price 1.66 | Shares 2,500
Buy 26 Oct 2021
Value US$3,338.80 | Price 1.67 | Shares 2,000
Buy 30 Apr 2021
Value US$4,970.04 | Price 2.28 | Shares 2,183
Buy 4 Mar 2021
Value US$6,250.00 | Price 2.50 | Shares 2,500
Buy 3 Mar 2021
Value US$7,260.00 | Price 2.42 | Shares 3,000
Buy 10 Dec 2020
Value US$4,975.00 | Price 1.99 | Shares 2,500
Buy 30 Nov 2020
Value US$4,708.00 | Price 2.14 | Shares 2,200
Buy 25 Aug 2020
Value US$7,464.90 | Price 2.49 | Shares 3,000
Buy 13 Aug 2020
Value US$28,000.00 | Price 2.80 | Shares 10,000
Buy 12 Aug 2020
Value US$10,318.40 | Price 2.58 | Shares 4,000
Buy 12 Aug 2020
Value US$25,200.00 | Price 2.52 | Shares 10,000
Buy 22 Jun 2020
Value US$10,500.00 | Price 2.10 | Shares 5,000
Sale 14 Feb 2018
Value US$161,007.77 | Price 0.34 | Shares 473,831
Sale 13 Feb 2018
Value US$31,652.15 | Price 0.31 | Shares 101,710
Sale 12 Feb 2018
Value US$58,323.63 | Price 0.31 | Shares 185,272
Sale 9 Feb 2018
Value US$2,567.68 | Price 0.34 | Shares 7,552
Sale 8 Feb 2018
Value US$78,433.69 | Price 0.34 | Shares 228,603
Sale 11 Jan 2018
Value US$6,800.00 | Price 0.34 | Shares 20,000
Sale 11 Jan 2018
Value US$4,294.20 | Price 0.34 | Shares 12,630
Sale 11 Jan 2018
Value US$6,812.00 | Price 0.34 | Shares 20,000
Sale 11 Jan 2018
Value US$6,810.00 | Price 0.34 | Shares 20,000
Sale 10 Jan 2018
Value US$6,007.22 | Price 0.38 | Shares 15,796
Sale 9 Jan 2018
Value US$7,804.00 | Price 0.39 | Shares 20,000
Sale 9 Jan 2018
Value US$7,928.00 | Price 0.40 | Shares 20,000
Sale 9 Jan 2018
Value US$7,600.00 | Price 0.38 | Shares 20,000
Sale 9 Jan 2018
Value US$7,600.00 | Price 0.38 | Shares 20,000
Sale 9 Jan 2018
Value US$7,400.00 | Price 0.37 | Shares 20,000
Buy 10 Aug 2016
Value US$5,075.00 | Price 2.03 | Shares 2,500
Buy 14 Jun 2016
Value US$2,100.00 | Price 2.10 | Shares 1,000
Buy 14 Jun 2016
Value US$10,500.00 | Price 2.10 | Shares 5,000
Buy 13 May 2016
Value US$5,420.00 | Price 2.71 | Shares 2,000
Buy 9 Mar 2016
Value US$18,860.00 | Price 0.19 | Shares 100,000
Buy 9 Mar 2016
Value US$9,430.00 | Price 0.19 | Shares 50,000
Buy 3 Sep 2015
Value US$9,530.65 | Price 0.37 | Shares 25,449
Buy 2 Sep 2015
Value US$2,911.00 | Price 0.36 | Shares 8,200
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-11-05 2025-11-04 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
25,689 +27.1%
353.15
US$3,980,365 		25,689 +27.1% 353.15 US$3,980,365
2025-08-25 2025-08-22 B Purchase
2.1
Lenk Robert P
Non-Executive Director
67,681 -46.0%
351.22
US$3,929,310 		67,681 -46.0% 351.22 US$3,929,310
2025-05-07 2025-05-15 PrS Proposed sale
3.1
Petersen Greg

Director

Non-Executive Director
67,356
268.44
US$3,194,986 		67,356 268.44 US$3,194,986
2024-09-17 2024-09-13 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
4,000 +35.8%
1.50
US$5,996 		4,000 +35.8% 1.50 US$5,996
2024-09-16 2024-09-12 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
6,285 +128.2%
1.35
US$8,512 		6,285 +128.2% 1.35 US$8,512
2024-09-13 2024-09-11 B Purchase
2.8
Clowes Howard
Non-Executive Director
5,000 +23.3%
1.34
US$6,681 		5,000 +23.3% 1.34 US$6,681
2024-09-13 2024-09-11 B Purchase
3.1
Petersen Greg
Non-Executive Director
12,500 +34.3%
1.35
US$16,875 		12,500 +34.3% 1.35 US$16,875
2024-09-11 2024-09-10 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
4,098 +71.7%
1.27
US$5,204 		4,098 +71.7% 1.27 US$5,204
2024-09-11 2024-09-10 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
8,000 +64.4%
1.23
US$9,839 		8,000 +64.4% 1.23 US$9,839
2024-05-10 2024-05-08 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,167 +16.6%
2.04
US$8,501 		4,167 +16.6% 2.04 US$8,501
2024-05-10 2024-05-08 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,167 +16.6%
2.04
US$8,501 		4,167 +16.6% 2.04 US$8,501
2024-05-10 2024-05-08 B Purchase
2.8
Clowes Howard
Non-Executive Director
9,804 +83.8%
2.04
US$20,000 		9,804 +83.8% 2.04 US$20,000
2024-05-10 2024-05-08 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
12,255 +7208.8%
2.04
US$25,000 		12,255 +7208.8% 2.04 US$25,000
2024-05-10 2024-05-08 B Purchase
3.1
Petersen Greg
Non-Executive Director
12,255 +50.7%
2.04
US$25,000 		12,255 +50.7% 2.04 US$25,000
2024-05-10 2024-05-08 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
4,902 +601.5%
2.04
US$10,000 		4,902 +601.5% 2.04 US$10,000
2024-05-10 2024-05-08 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
4,902 +490200.0%
2.04
US$10,000 		4,902 +490200.0% 2.04 US$10,000
2023-12-15 2023-11-20 S Sale
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,068 -92.4%
1.96
US$4,053 		2,068 -92.4% 1.96 US$4,053
2023-11-17 2023-11-16 B Purchase
2.1
Lenk Robert P
Non-Executive Director
1,000 +4.1%
1.95
US$1,950 		1,000 +4.1% 1.95 US$1,950
2023-11-17 2023-11-15 B Purchase
2.1
Lenk Robert P
Non-Executive Director
1,000 +4.3%
1.77
US$1,770 		1,000 +4.3% 1.77 US$1,770
2023-11-15 2023-11-13 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,000 +20.9%
1.43
US$5,720 		4,000 +20.9% 1.43 US$5,720
2023-11-15 2023-11-10 B Purchase
2.1
Lenk Robert P
Non-Executive Director
2,000 +11.7%
1.45
US$2,900 		2,000 +11.7% 1.45 US$2,900
2023-11-13 2023-11-09 B Purchase
2.1
Lenk Robert P
Non-Executive Director
4,199 +32.4%
1.59
US$6,676 		4,199 +32.4% 1.59 US$6,676
2023-11-13 2023-11-08 B Purchase
2.1
Lenk Robert P
Non-Executive Director
5,000 +62.8%
1.65
US$8,250 		5,000 +62.8% 1.65 US$8,250
2023-11-08 2023-11-07 B Purchase
2.1
Lenk Robert P
Non-Executive Director
6,000 +306.0%
1.64
US$9,840 		6,000 +306.0% 1.64 US$9,840
2023-11-08 2023-11-06 B Purchase
2.1
Lenk Robert P
Non-Executive Director
1,395 +246.5%
1.50
US$2,092 		1,395 +246.5% 1.50 US$2,092
2023-09-15 2023-09-13 B Purchase
2.8
Clowes Howard
Non-Executive Director
6,993 +148.8%
1.43
US$10,022 		6,993 +148.8% 1.43 US$10,022
2023-09-12 2023-09-11 B Purchase
3.1
Petersen Greg
Non-Executive Director
20,000 +480.1%
1.70
US$34,062 		20,000 +480.1% 1.70 US$34,062
2023-06-08 2023-06-06 B Purchase
2.8
Clowes Howard
Non-Executive Director
1,000 +27.0%
3.98
US$3,980 		1,000 +27.0% 3.98 US$3,980
2023-05-04 2023-05-03 B Purchase
2.8
Clowes Howard
Non-Executive Director
2,500 +208.3%
3.64
US$9,102 		2,500 +208.3% 3.64 US$9,102
2023-03-06 2023-03-03 B Purchase
4.2
Hawkins Richard J
Non-Executive Director
1 +inf%
1,000.00
US$1,000 		1 +inf% 1,000.00 US$1,000
2023-01-04 2022-12-30 S Sale
2.1
Lenk Robert P
Non-Executive Director
1,500 -15.0%
0.31
US$472 		1,500 -15.0% 0.31 US$472
2022-06-16 2022-06-15 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
5,000 +17.5%
0.65
US$3,240 		5,000 +17.5% 0.65 US$3,240
2022-06-06 2022-06-02 B Purchase
2.8
Clowes Howard
Non-Executive Director
15,000 +500.0%
0.57
US$8,589 		15,000 +500.0% 0.57 US$8,589
2022-05-19 2022-05-17 B Purchase
3.1
Petersen Greg
Non-Executive Director
30,000 +92.3%
0.55
US$16,500 		30,000 +92.3% 0.55 US$16,500
2022-04-28 2022-04-26 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +9.6%
0.68
US$1,710 		2,500 +9.6% 0.68 US$1,710
2022-04-27 2022-04-26 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
5,000 +23.7%
0.69
US$3,450 		5,000 +23.7% 0.69 US$3,450
2022-04-27 2022-04-26 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
3,000 +32.5%
0.67
US$2,016 		3,000 +32.5% 0.67 US$2,016
2022-03-03 2022-03-01 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
2,000 +27.7%
1.10
US$2,200 		2,000 +27.7% 1.10 US$2,200
2021-11-04 2021-11-02 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
1,000 +16.1%
1.86
US$1,864 		1,000 +16.1% 1.86 US$1,864
2021-10-28 2021-10-27 B Purchase
3.1
Petersen Greg
Non-Executive Director
12,500 +62.5%
1.72
US$21,500 		12,500 +62.5% 1.72 US$21,500
2021-10-27 2021-10-26 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +13.5%
1.66
US$4,150 		2,500 +13.5% 1.66 US$4,150
2021-10-27 2021-10-26 B Purchase
2.6
Sims Andrew John Hugh MacIntyre

Chief Financial Officer

Officer
2,000 +47.3%
1.67
US$3,339 		2,000 +47.3% 1.67 US$3,339
2021-05-03 2021-04-30 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,183 +13.3%
2.28
US$4,970 		2,183 +13.3% 2.28 US$4,970
2021-03-05 2021-03-04 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +18.0%
2.50
US$6,250 		2,500 +18.0% 2.50 US$6,250
2021-03-04 2021-03-03 B Purchase
2.8
Clowes Howard
Non-Executive Director
3,000 +inf%
2.42
US$7,260 		3,000 +inf% 2.42 US$7,260
2020-12-14 2020-12-10 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Executive Director
2,500 +22.0%
1.99
US$4,975 		2,500 +22.0% 1.99 US$4,975
2020-12-02 2020-11-30 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Officer
2,200 +24.0%
2.14
US$4,708 		2,200 +24.0% 2.14 US$4,708
2020-08-26 2020-08-25 B Purchase
2.1
Lenk Robert P
Non-Executive Director
3,000 +inf%
2.49
US$7,465 		3,000 +inf% 2.49 US$7,465
2020-08-14 2020-08-13 B Purchase
3.1
Petersen Greg
Non-Executive Director
10,000 +100.0%
2.80
US$28,000 		10,000 +100.0% 2.80 US$28,000
2020-08-13 2020-08-12 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Officer
4,000 +77.4%
2.58
US$10,318 		4,000 +77.4% 2.58 US$10,318
2020-08-13 2020-08-12 B Purchase
3.1
Petersen Greg
Non-Executive Director
10,000 +inf%
2.52
US$25,200 		10,000 +inf% 2.52 US$25,200
2020-06-23 2020-06-22 B Purchase
1.9
HEDRICK MARC H

Chief Executive Officer

Officer
5,000 +2994.0%
2.10
US$10,500 		5,000 +2994.0% 2.10 US$10,500
2018-02-15 2018-02-14 S Sale PostFinance AG Large shareholder
473,831 -9.4%
0.34
US$161,008 		473,831 -9.4% 0.34 US$161,008
2018-02-14 2018-02-13 S Sale PostFinance AG Large shareholder
101,710 -2.0%
0.31
US$31,652 		101,710 -2.0% 0.31 US$31,652
2018-02-14 2018-02-12 S Sale PostFinance AG Large shareholder
185,272 -3.5%
0.31
US$58,324 		185,272 -3.5% 0.31 US$58,324
2018-02-12 2018-02-09 S Sale PostFinance AG Large shareholder
7,552 -0.1%
0.34
US$2,568 		7,552 -0.1% 0.34 US$2,568
2018-02-12 2018-02-08 S Sale PostFinance AG Large shareholder
228,603 -4.1%
0.34
US$78,434 		228,603 -4.1% 0.34 US$78,434
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
20,000 -0.4%
0.34
US$6,800 		20,000 -0.4% 0.34 US$6,800
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
12,630 -0.2%
0.34
US$4,294 		12,630 -0.2% 0.34 US$4,294
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
20,000 -0.4%
0.34
US$6,812 		20,000 -0.4% 0.34 US$6,812
2018-01-11 2018-01-11 S Sale Swissquote Bank SA
20,000 -0.4%
0.34
US$6,810 		20,000 -0.4% 0.34 US$6,810
2018-01-11 2018-01-10 S Sale Swissquote Bank SA
15,796 -0.3%
0.38
US$6,007 		15,796 -0.3% 0.38 US$6,007
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.39
US$7,804 		20,000 -0.4% 0.39 US$7,804
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.40
US$7,928 		20,000 -0.4% 0.40 US$7,928
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.38
US$7,600 		20,000 -0.4% 0.38 US$7,600
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.38
US$7,600 		20,000 -0.4% 0.38 US$7,600
2018-01-11 2018-01-09 S Sale Swissquote Bank SA
20,000 -0.4%
0.37
US$7,400 		20,000 -0.4% 0.37 US$7,400
2016-08-11 2016-08-10 B Purchase HARRIS JOHN DAVID

VP and GM Cell Therapy

Officer
2,500 +55.6%
2.03
US$5,075 		2,500 +55.6% 2.03 US$5,075
2016-06-15 2016-06-14 B Purchase Naughton Gail K Non-Executive Director
1,000 +71.4%
2.10
US$2,100 		1,000 +71.4% 2.10 US$2,100
2016-06-15 2016-06-14 B Purchase RICKEY DAVID Non-Executive Director
5,000 +10.0%
2.10
US$10,500 		5,000 +10.0% 2.10 US$10,500
2016-05-16 2016-05-13 B Purchase HARRIS JOHN DAVID

VP and GM Cell Therapy

Officer
2,000 +inf%
2.71
US$5,420 		2,000 +inf% 2.71 US$5,420
2016-03-09 2016-03-09 B Purchase RICKEY DAVID Non-Executive Director
100,000 +15.3%
0.19
US$18,860 		100,000 +15.3% 0.19 US$18,860
2016-03-09 2016-03-09 B Purchase RICKEY DAVID Non-Executive Director
50,000 +22.7%
0.19
US$9,430 		50,000 +22.7% 0.19 US$9,430
2015-09-08 2015-09-03 B Purchase Thompson Tommy G Non-Executive Director
25,449 +43.8%
0.37
US$9,531 		25,449 +43.8% 0.37 US$9,531
2015-09-03 2015-09-02 B Purchase HAYDEN JEREMY B.

General Counsel & VP of BD

Officer
8,200 +45.6%
0.36
US$2,911 		8,200 +45.6% 0.36 US$2,911
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