United States Healthcare Equipment & Supplies

Caris Life Sciences Inc (CAI)

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Caris Life Sciences experienced significant insider selling totaling over $57.5 million during the past quarter. Key executives, including President David Spetzler and Brian Brille, offloaded substantial equity stakes. These divestments follow a period of strong stock appreciation, despite a recent disappointing earnings report. No open market purchases were recorded by leadership during this timeframe.
Ticker: CAI Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Caris Life Sciences Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
1.6
JOHN RUSSEL DENTON Officer Officer
Transaction date
Proposed sale
Price
446.96
Quantity 78,620
Value US$927,761
Brille Brian J See Remarks Executive Director
Transaction date
Sale
Price
263.18
Quantity 43,210 -23.6%
Value US$996,280
BRIAN J BRILLE Officer; Director Executive Director
Transaction date
Proposed sale
Price
447.22
Quantity 32,540
Value US$3,279,055
1.9
Spetzler David Baxley President Officer
Transaction date
Sale
Price
24.76
Quantity 1,000 -9.2%
Value US$100,000
1.9
DAVID SPETZLER Officer Officer
Transaction date
Proposed sale
Price
24.76
Quantity 1,000
Value US$100,000
1.9
Spetzler David Baxley President Officer
Transaction date
Sale
Price
25.32
Quantity 1,000 -7.5%
Value US$100,000
1.9
Spetzler David Baxley President Officer
Transaction date
Sale
Price
24.76
Quantity 1,000 -25.7%
Value US$100,000
1.9
DAVID SPETZLER Officer Officer
Transaction date
Proposed sale
Price
24.86
Quantity 1,000
Value US$100,000
2.5
GEORGE H POSTE REVOCABLE TRUST Former Affiliate
Transaction date
Proposed sale
Price
26.06
Quantity 100,000
Value US$2,606,320
2.5
GEORGE H POSTE Director Non-Executive Director
Transaction date
Proposed sale
Price
21.42
Quantity 30,000
Value US$642,633
2.5
GEORGE H POSTE Director Non-Executive Director
Transaction date
Proposed sale
Price
16.25
Quantity 20,000
Value US$325,000
3.3
HALBERT JON Non-Executive Director
Transaction date
Purchase
Price
14.56
Quantity 68,000 +10.7%
Value US$990,080
3.7
Vacirca Jeff L Non-Executive Director
Transaction date
Purchase
Price
16.15
Quantity 31,050 +166.7%
Value US$501,426
Power Luke Thomas See Remarks Officer
Transaction date
Planned sale
Price
27.16
Quantity 1,400 -1.4%
Value US$38,018
Power Luke Thomas See Remarks Officer
Transaction date
Planned sale
Price
26.56
Quantity 60,850 -37.6%
Value US$1,616,444
LUKE POWER Officer Officer
Transaction date
Proposed sale
Price
27.10
Quantity 62,250
Value US$1,686,975
1.6
Denton John Russel See Remarks Officer
Transaction date
Purchase
Price
24.09
Quantity 4,184 +83.7%
Value US$100,793
1.9
Spetzler David Baxley President Officer
Transaction date
Purchase
Price
23.85
Quantity 400 +0.1%
Value US$9,540
1.6
Denton John Russel See Remarks Officer
Transaction date
Purchase
Price
21.00
Quantity 7,500 +6.5%
Value US$157,500
Brille Brian J See Remarks Executive Director
Transaction date
Purchase
Price
21.00
Quantity 30,000 +22.7%
Value US$630,000
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-09-22 2026-09-22 PrS Proposed sale
1.6
JOHN RUSSEL DENTON

Officer

Officer
78,620
446.96
US$927,761 		78,620 446.96 US$927,761
2026-09-17 2026-09-17 S Sale
Brille Brian J

See Remarks

Executive Director
43,210 -23.6%
263.18
US$996,280 		43,210 -23.6% 263.18 US$996,280
2026-09-17 2026-09-17 PrS Proposed sale
BRIAN J BRILLE

Officer; Director

Executive Director
32,540
447.22
US$3,279,055 		32,540 447.22 US$3,279,055
2026-09-04 2026-09-04 S Sale
1.9
Spetzler David Baxley

President

Officer
1,000 -9.2%
24.76
US$100,000 		1,000 -9.2% 24.76 US$100,000
2026-09-04 2026-09-04 PrS Proposed sale
1.9
DAVID SPETZLER

Officer

Officer
1,000
24.76
US$100,000 		1,000 24.76 US$100,000
2026-09-04 2026-09-03 S Sale
1.9
Spetzler David Baxley

President

Officer
1,000 -7.5%
25.32
US$100,000 		1,000 -7.5% 25.32 US$100,000
2026-09-04 2026-09-03 S Sale
1.9
Spetzler David Baxley

President

Officer
1,000 -25.7%
24.76
US$100,000 		1,000 -25.7% 24.76 US$100,000
2026-09-03 2026-09-03 PrS Proposed sale
1.9
DAVID SPETZLER

Officer

Officer
1,000
24.86
US$100,000 		1,000 24.86 US$100,000
2026-08-24 2026-08-24 PrS Proposed sale
2.5
GEORGE H POSTE REVOCABLE TRUST

Former Affiliate
100,000
26.06
US$2,606,320 		100,000 26.06 US$2,606,320
2026-08-07 2026-08-07 PrS Proposed sale
2.5
GEORGE H POSTE

Director

Non-Executive Director
30,000
21.42
US$642,633 		30,000 21.42 US$642,633
2026-08-03 2026-08-03 PrS Proposed sale
2.5
GEORGE H POSTE

Director

Non-Executive Director
20,000
16.25
US$325,000 		20,000 16.25 US$325,000
2026-07-13 2026-05-15 B Purchase
3.3
HALBERT JON
Non-Executive Director
68,000 +10.7%
14.56
US$990,080 		68,000 +10.7% 14.56 US$990,080
2026-05-12 2026-05-11 B Purchase
3.7
Vacirca Jeff L
Non-Executive Director
31,050 +166.7%
16.15
US$501,426 		31,050 +166.7% 16.15 US$501,426
2025-12-12 2025-12-11 PlS Planned sale
Power Luke Thomas

See Remarks

Officer
1,400 -1.4%
27.16
US$38,018 		1,400 -1.4% 27.16 US$38,018
2025-12-12 2025-12-11 PlS Planned sale
Power Luke Thomas

See Remarks

Officer
60,850 -37.6%
26.56
US$1,616,444 		60,850 -37.6% 26.56 US$1,616,444
2025-12-11 2025-12-11 PrS Proposed sale
LUKE POWER

Officer

Officer
62,250
27.10
US$1,686,975 		62,250 27.10 US$1,686,975
2025-11-10 2025-11-07 B Purchase
1.6
Denton John Russel

See Remarks

Officer
4,184 +83.7%
24.09
US$100,793 		4,184 +83.7% 24.09 US$100,793
2025-11-10 2025-11-07 B Purchase
1.9
Spetzler David Baxley

President

Officer
400 +0.1%
23.85
US$9,540 		400 +0.1% 23.85 US$9,540
2025-06-23 2025-06-20 B Purchase
1.6
Denton John Russel

See Remarks

Officer
7,500 +6.5%
21.00
US$157,500 		7,500 +6.5% 21.00 US$157,500
2025-06-23 2025-06-20 B Purchase
Brille Brian J

See Remarks

Executive Director
30,000 +22.7%
21.00
US$630,000 		30,000 +22.7% 21.00 US$630,000
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