Bicycle Therapeutics PLC (BCYC)

Bicycle Therapeutics experienced nineteen insider trading transactions over the past ninety days, all involving sales totaling approximately $143,602. Key executives, including the CEO and COO, offloaded shares following a recent earnings report that missed expectations. The stock price has declined 8.5% during this period, reflecting broader market sentiment surrounding the firm.
Ticker: BCYC Exchange: NSM


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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Bicycle Therapeutics PLC. Upgrade to see score, net flow, insiders and the full signal context.

Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Planned sale
Price
442.57
Quantity 54,725 +42.2%
Value US$993,786
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Planned sale
Price
385.21
Quantity 76,566 +44.8%
Value US$4,486,860
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Sale
Price
188.93
Quantity 47,685 +10.8%
Value US$4,673,456
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Sale
Price
4.31
Quantity 43 -0.0%
Value US$185
3.8
Skynner Michael CHIEF SCIENTIFIC OFFICER Officer
Transaction date
Sale
Price
4.31
Quantity 532 -0.3%
Value US$2,293
3.8
Skynner Michael CHIEF SCIENTIFIC OFFICER Officer
Transaction date
Sale
Price
4.31
Quantity 532 -0.3%
Value US$2,293
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
4.31
Quantity 1,737 -0.3%
Value US$7,486
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
4.31
Quantity 1,737 -0.3%
Value US$7,486
3.9
Thompson Travis Alvin Chief Financial Officer Officer
Transaction date
Sale
Price
4.31
Quantity 104 -0.2%
Value US$448
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Sale
Price
4.27
Quantity 1,036 -1.1%
Value US$4,424
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Sale
Price
4.27
Quantity 1,036 -1.1%
Value US$4,424
3.8
Skynner Michael CHIEF SCIENTIFIC OFFICER Officer
Transaction date
Sale
Price
4.27
Quantity 1,859 -1.2%
Value US$7,938
3.8
Skynner Michael CHIEF SCIENTIFIC OFFICER Officer
Transaction date
Sale
Price
4.27
Quantity 1,859 -1.2%
Value US$7,938
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
4.27
Quantity 5,905 -1.0%
Value US$25,214
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
4.27
Quantity 5,905 -1.0%
Value US$25,214
3.9
Thompson Travis Alvin Chief Financial Officer Officer
Transaction date
Sale
Price
4.27
Quantity 819 -1.3%
Value US$3,497
3.7
Lee Kevin Officer Officer
Transaction date
Proposed sale
Price
4.27
Quantity 8,000
Value US$34,155
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
5.05
Quantity 1,716 -0.3%
Value US$8,666
3.8
Skynner Michael CHIEF SCIENTIFIC OFFICER Officer
Transaction date
Sale
Price
5.05
Quantity 525 -0.3%
Value US$2,651
3.9
Thompson Travis Alvin Chief Financial Officer Officer
Transaction date
Sale
Price
5.05
Quantity 102 -0.2%
Value US$515
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Planned sale
Price
5.04
Quantity 333 -0.4%
Value US$1,678
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Sale
Price
5.05
Quantity 37 -0.0%
Value US$187
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
4.91
Quantity 5,967 -1.0%
Value US$29,298
3.8
Skynner Michael CHIEF SCIENTIFIC OFFICER Officer
Transaction date
Sale
Price
4.91
Quantity 1,879 -1.2%
Value US$9,226
3.9
Thompson Travis Alvin Chief Financial Officer Officer
Transaction date
Sale
Price
4.91
Quantity 799 -1.2%
Value US$3,923
3.3
Perry Jennifer Scott Chief Operating Officer Officer
Transaction date
Sale
Price
4.91
Quantity 1,038 -1.1%
Value US$5,097
4.2
Young Alethia Officer Officer
Transaction date
Proposed sale
Price
4.91
Quantity 2,034
Value US$9,977
3.3
Perry Jennifer Scott Officer Officer
Transaction date
Proposed sale
Price
4.91
Quantity 1,500
Value US$7,358
3.9
Thompson Travis Alvin Officer Officer
Transaction date
Proposed sale
Price
4.91
Quantity 1,000
Value US$4,905
3.8
Skynner Michael Officer Officer
Transaction date
Proposed sale
Price
4.91
Quantity 2,500
Value US$12,263
3.8
Milnes Alistair Officer Officer
Transaction date
Proposed sale
Price
4.91
Quantity 2,850
Value US$13,980
3.7
Lee Kevin Officer Officer
Transaction date
Proposed sale
Price
4.91
Quantity 8,000
Value US$39,242
3.8
Skynner Michael CHIEF TECHNOLOGY OFFICER Officer
Transaction date
Sale
Price
6.46
Quantity 3,266 -2.0%
Value US$21,098
3.8
Milnes Alistair CHIEF OPERATING OFFICER Officer
Transaction date
Sale
Price
6.46
Quantity 3,416 -2.4%
Value US$22,067
4.2
Young Alethia Chief Financial Officer Officer
Transaction date
Planned sale
Price
6.54
Quantity 1,878 -2.1%
Value US$12,282
4.2
Young Alethia Chief Financial Officer Officer
Transaction date
Sale
Price
6.45
Quantity 2,456 -2.7%
Value US$15,841
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
6.46
Quantity 10,989 -1.7%
Value US$70,989
3.9
Thompson Travis Alvin CHIEF ACCOUNTING OFFICER Officer
Transaction date
Sale
Price
6.45
Quantity 1,115 -1.7%
Value US$7,192
4.2
Young Alethia Officer Officer
Transaction date
Proposed sale
Price
6.53
Quantity 123
Value US$803
3.8
Skynner Michael CHIEF TECHNOLOGY OFFICER Officer
Transaction date
Sale
Price
6.80
Quantity 3,045 -1.8%
Value US$20,706
3.8
Milnes Alistair CHIEF OPERATING OFFICER Officer
Transaction date
Sale
Price
6.80
Quantity 3,244 -2.3%
Value US$22,059
4.2
Young Alethia Chief Financial Officer Officer
Transaction date
Sale
Price
6.80
Quantity 3,289 -3.5%
Value US$22,365
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
6.80
Quantity 10,325 -1.6%
Value US$70,210
3.9
Thompson Travis Alvin CHIEF ACCOUNTING OFFICER Officer
Transaction date
Sale
Price
6.80
Quantity 1,317 -1.9%
Value US$8,956
3.8
Milnes Alistair Officer Officer
Transaction date
Proposed sale
Price
6.94
Quantity 6,750
Value US$46,850
3.8
Skynner Michael Officer Officer
Transaction date
Proposed sale
Price
6.80
Quantity 6,400
Value US$43,507
3.9
Thompson Travis Alvin Officer Officer
Transaction date
Proposed sale
Price
6.80
Quantity 2,750
Value US$18,695
4.2
Young Alethia Officer Officer
Transaction date
Proposed sale
Price
6.80
Quantity 7,500
Value US$50,985
3.7
Lee Kevin Officer Officer
Transaction date
Proposed sale
Price
6.80
Quantity 21,500
Value US$146,157
3.9
Thompson Travis Alvin CHIEF ACCOUNTING OFFICER Officer
Transaction date
Sale
Price
8.41
Quantity 103 -0.3%
Value US$866
3.8
Skynner Michael CHIEF TECHNOLOGY OFFICER Officer
Transaction date
Sale
Price
8.41
Quantity 978 -0.8%
Value US$8,225
3.8
Milnes Alistair CHIEF OPERATING OFFICER Officer
Transaction date
Sale
Price
8.41
Quantity 978 -1.0%
Value US$8,225
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
8.41
Quantity 3,231 -0.7%
Value US$27,173
3.9
Thompson Travis Alvin CHIEF ACCOUNTING OFFICER Officer
Transaction date
Sale
Price
8.40
Quantity 221 -0.7%
Value US$1,856
Swanton Robert Charles Non-Executive Director
Transaction date
Planned sale
Price
8.55
Quantity 102 -0.7%
Value US$872
3.8
Skynner Michael CHIEF TECHNOLOGY OFFICER Officer
Transaction date
Sale
Price
8.40
Quantity 824 -0.7%
Value US$6,922
4.2
Young Alethia Chief Financial Officer Officer
Transaction date
Planned sale
Price
8.61
Quantity 265 -0.6%
Value US$2,280
4.2
Young Alethia Chief Financial Officer Officer
Transaction date
Sale
Price
8.40
Quantity 217 -0.5%
Value US$1,823
3.8
Milnes Alistair CHIEF OPERATING OFFICER Officer
Transaction date
Sale
Price
8.40
Quantity 1,147 -1.2%
Value US$9,635
3.7
Lee Kevin CHIEF EXECUTIVE OFFICER Executive Director
Transaction date
Sale
Price
8.40
Quantity 2,263 -0.5%
Value US$19,009
Swanton Robert Charles Director Non-Executive Director
Transaction date
Proposed sale
Price
8.55
Quantity 102
Value US$872
3.9
Thompson Travis Alvin Officer Officer
Transaction date
Proposed sale
Price
8.40
Quantity 543
Value US$4,563
4.2
Young Alethia Officer Officer
Transaction date
Proposed sale
Price
7.09
Quantity 486
Value US$3,447
3.7
Lee Kevin Officer Officer
Transaction date
Proposed sale
Price
8.40
Quantity 5,958
Value US$50,061
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Value Details
2026-07-07 2026-07-06 PlS Planned sale

Chief Operating Officer

Officer
54,725 +42.2%
442.57
US$993,786
54,725 +42.2% 442.57 US$993,786
2026-07-07 2026-07-06 PlS Planned sale

Chief Operating Officer

Officer
76,566 +44.8%
385.21
US$4,486,860
76,566 +44.8% 385.21 US$4,486,860
2026-07-07 2026-07-06 S Sale

Chief Operating Officer

Officer
47,685 +10.8%
188.93
US$4,673,456
47,685 +10.8% 188.93 US$4,673,456
2026-07-07 2026-07-06 S Sale

Chief Operating Officer

Officer
43 -0.0%
4.31
US$185
43 -0.0% 4.31 US$185
2026-07-07 2026-07-06 S Sale

CHIEF SCIENTIFIC OFFICER

Officer
532 -0.3%
4.31
US$2,293
532 -0.3% 4.31 US$2,293
2026-07-07 2026-07-06 S Sale

CHIEF SCIENTIFIC OFFICER

Officer
532 -0.3%
4.31
US$2,293
532 -0.3% 4.31 US$2,293
2026-07-07 2026-07-06 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
1,737 -0.3%
4.31
US$7,486
1,737 -0.3% 4.31 US$7,486
2026-07-07 2026-07-06 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
1,737 -0.3%
4.31
US$7,486
1,737 -0.3% 4.31 US$7,486
2026-07-07 2026-07-06 S Sale

Chief Financial Officer

Officer
104 -0.2%
4.31
US$448
104 -0.2% 4.31 US$448
2026-07-07 2026-07-06 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
255 -0.3%
4.31
US$1,099
255 -0.3% 4.31 US$1,099
2026-07-07 2026-07-02 S Sale

Chief Operating Officer

Officer
1,036 -1.1%
4.27
US$4,424
1,036 -1.1% 4.27 US$4,424
2026-07-07 2026-07-02 S Sale

Chief Operating Officer

Officer
1,036 -1.1%
4.27
US$4,424
1,036 -1.1% 4.27 US$4,424
2026-07-07 2026-07-02 S Sale

CHIEF SCIENTIFIC OFFICER

Officer
1,859 -1.2%
4.27
US$7,938
1,859 -1.2% 4.27 US$7,938
2026-07-07 2026-07-02 S Sale

CHIEF SCIENTIFIC OFFICER

Officer
1,859 -1.2%
4.27
US$7,938
1,859 -1.2% 4.27 US$7,938
2026-07-07 2026-07-02 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
5,905 -1.0%
4.27
US$25,214
5,905 -1.0% 4.27 US$25,214
2026-07-07 2026-07-02 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
5,905 -1.0%
4.27
US$25,214
5,905 -1.0% 4.27 US$25,214
2026-07-07 2026-07-02 S Sale

Chief Financial Officer

Officer
819 -1.3%
4.27
US$3,497
819 -1.3% 4.27 US$3,497
2026-07-07 2026-07-02 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
1,506 -1.6%
4.27
US$6,431
1,506 -1.6% 4.27 US$6,431
2026-07-02 2026-07-02 PrS Proposed sale

Officer

Officer
8,000
4.27
US$34,155
8,000 4.27 US$34,155
2026-04-06 2026-04-06 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
1,716 -0.3%
5.05
US$8,666
1,716 -0.3% 5.05 US$8,666
2026-04-06 2026-04-06 S Sale

CHIEF SCIENTIFIC OFFICER

Officer
525 -0.3%
5.05
US$2,651
525 -0.3% 5.05 US$2,651
2026-04-06 2026-04-06 S Sale

Chief Financial Officer

Officer
102 -0.2%
5.05
US$515
102 -0.2% 5.05 US$515
2026-04-06 2026-04-06 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
251 -0.3%
5.05
US$1,268
251 -0.3% 5.05 US$1,268
2026-04-06 2026-04-06 PlS Planned sale

Chief Operating Officer

Officer
333 -0.4%
5.04
US$1,678
333 -0.4% 5.04 US$1,678
2026-04-06 2026-04-06 S Sale

Chief Operating Officer

Officer
37 -0.0%
5.05
US$187
37 -0.0% 5.05 US$187
2026-04-06 2026-04-02 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
5,967 -1.0%
4.91
US$29,298
5,967 -1.0% 4.91 US$29,298
2026-04-06 2026-04-02 S Sale

CHIEF SCIENTIFIC OFFICER

Officer
1,879 -1.2%
4.91
US$9,226
1,879 -1.2% 4.91 US$9,226
2026-04-06 2026-04-02 S Sale

Chief Financial Officer

Officer
799 -1.2%
4.91
US$3,923
799 -1.2% 4.91 US$3,923
2026-04-06 2026-04-02 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
1,521 -1.6%
4.91
US$7,468
1,521 -1.6% 4.91 US$7,468
2026-04-06 2026-04-02 S Sale

Chief Operating Officer

Officer
1,038 -1.1%
4.91
US$5,097
1,038 -1.1% 4.91 US$5,097
2026-04-02 2026-04-02 PrS Proposed sale

Officer

Officer
2,034
4.91
US$9,977
2,034 4.91 US$9,977
2026-04-02 2026-04-02 PrS Proposed sale

Officer

Officer
1,500
4.91
US$7,358
1,500 4.91 US$7,358
2026-04-02 2026-04-02 PrS Proposed sale

Officer

Officer
1,850
4.91
US$9,075
1,850 4.91 US$9,075
2026-04-02 2026-04-02 PrS Proposed sale

Officer

Officer
1,000
4.91
US$4,905
1,000 4.91 US$4,905
2026-04-02 2026-04-02 PrS Proposed sale

Officer

Officer
2,500
4.91
US$12,263
2,500 4.91 US$12,263
2026-04-02 2026-04-02 PrS Proposed sale

Officer

Officer
2,850
4.91
US$13,980
2,850 4.91 US$13,980
2026-04-02 2026-04-02 PrS Proposed sale

Officer

Officer
8,000
4.91
US$39,242
8,000 4.91 US$39,242
2026-01-06 2026-01-05 S Sale

CHIEF TECHNOLOGY OFFICER

Officer
3,266 -2.0%
6.46
US$21,098
3,266 -2.0% 6.46 US$21,098
2026-01-06 2026-01-05 S Sale

CHIEF OPERATING OFFICER

Officer
3,416 -2.4%
6.46
US$22,067
3,416 -2.4% 6.46 US$22,067
2026-01-06 2026-01-05 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
2,367 -2.4%
6.45
US$15,267
2,367 -2.4% 6.45 US$15,267
2026-01-06 2026-01-05 PlS Planned sale

Chief Financial Officer

Officer
1,878 -2.1%
6.54
US$12,282
1,878 -2.1% 6.54 US$12,282
2026-01-06 2026-01-05 S Sale

Chief Financial Officer

Officer
2,456 -2.7%
6.45
US$15,841
2,456 -2.7% 6.45 US$15,841
2026-01-06 2026-01-05 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
10,989 -1.7%
6.46
US$70,989
10,989 -1.7% 6.46 US$70,989
2026-01-06 2026-01-05 S Sale

CHIEF ACCOUNTING OFFICER

Officer
1,115 -1.7%
6.45
US$7,192
1,115 -1.7% 6.45 US$7,192
2026-01-05 2026-01-05 PrS Proposed sale

Officer

Officer
123
6.53
US$803
123 6.53 US$803
2026-01-06 2026-01-02 S Sale

CHIEF TECHNOLOGY OFFICER

Officer
3,045 -1.8%
6.80
US$20,706
3,045 -1.8% 6.80 US$20,706
2026-01-06 2026-01-02 S Sale

CHIEF OPERATING OFFICER

Officer
3,244 -2.3%
6.80
US$22,059
3,244 -2.3% 6.80 US$22,059
2026-01-06 2026-01-02 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
2,827 -2.7%
6.80
US$19,224
2,827 -2.7% 6.80 US$19,224
2026-01-06 2026-01-02 S Sale

Chief Financial Officer

Officer
3,289 -3.5%
6.80
US$22,365
3,289 -3.5% 6.80 US$22,365
2026-01-06 2026-01-02 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
10,325 -1.6%
6.80
US$70,210
10,325 -1.6% 6.80 US$70,210
2026-01-06 2026-01-02 S Sale

CHIEF ACCOUNTING OFFICER

Officer
1,317 -1.9%
6.80
US$8,956
1,317 -1.9% 6.80 US$8,956
2026-01-02 2026-01-02 PrS Proposed sale

Officer

Officer
6,750
6.94
US$46,850
6,750 6.94 US$46,850
2026-01-02 2026-01-02 PrS Proposed sale

Officer

Officer
6,400
6.80
US$43,507
6,400 6.80 US$43,507
2026-01-02 2026-01-02 PrS Proposed sale

Officer

Officer
2,750
6.80
US$18,695
2,750 6.80 US$18,695
2026-01-02 2026-01-02 PrS Proposed sale

Officer

Officer
7,500
6.80
US$50,985
7,500 6.80 US$50,985
2026-01-02 2026-01-02 PrS Proposed sale

Officer

Officer
5,250
6.80
US$35,690
5,250 6.80 US$35,690
2026-01-02 2026-01-02 PrS Proposed sale

Officer

Officer
21,500
6.80
US$146,157
21,500 6.80 US$146,157
2025-10-06 2025-10-03 S Sale

CHIEF ACCOUNTING OFFICER

Officer
103 -0.3%
8.41
US$866
103 -0.3% 8.41 US$866
2025-10-06 2025-10-03 S Sale

CHIEF TECHNOLOGY OFFICER

Officer
978 -0.8%
8.41
US$8,225
978 -0.8% 8.41 US$8,225
2025-10-06 2025-10-03 S Sale

CHIEF OPERATING OFFICER

Officer
978 -1.0%
8.41
US$8,225
978 -1.0% 8.41 US$8,225
2025-10-06 2025-10-03 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
250 -0.5%
8.41
US$2,102
250 -0.5% 8.41 US$2,102
2025-10-06 2025-10-03 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
3,231 -0.7%
8.41
US$27,173
3,231 -0.7% 8.41 US$27,173
2025-10-06 2025-10-02 S Sale

CHIEF ACCOUNTING OFFICER

Officer
221 -0.7%
8.40
US$1,856
221 -0.7% 8.40 US$1,856
2025-10-06 2025-10-02 PlS Planned sale Non-Executive Director
102 -0.7%
8.55
US$872
102 -0.7% 8.55 US$872
2025-10-06 2025-10-02 S Sale

CHIEF TECHNOLOGY OFFICER

Officer
824 -0.7%
8.40
US$6,922
824 -0.7% 8.40 US$6,922
2025-10-06 2025-10-02 PlS Planned sale

Chief Financial Officer

Officer
265 -0.6%
8.61
US$2,280
265 -0.6% 8.61 US$2,280
2025-10-06 2025-10-02 S Sale

Chief Financial Officer

Officer
217 -0.5%
8.40
US$1,823
217 -0.5% 8.40 US$1,823
2025-10-06 2025-10-02 S Sale

CHIEF OPERATING OFFICER

Officer
1,147 -1.2%
8.40
US$9,635
1,147 -1.2% 8.40 US$9,635
2025-10-06 2025-10-02 S Sale

CHIEF PROD & SUPPLY CHAIN OFF

Officer
473 -0.9%
8.40
US$3,973
473 -0.9% 8.40 US$3,973
2025-10-06 2025-10-02 S Sale

CHIEF EXECUTIVE OFFICER

Executive Director
2,263 -0.5%
8.40
US$19,009
2,263 -0.5% 8.40 US$19,009
2025-10-02 2025-10-02 PrS Proposed sale

Director

Non-Executive Director
102
8.55
US$872
102 8.55 US$872
2025-10-02 2025-10-02 PrS Proposed sale

Officer

Officer
543
8.40
US$4,563
543 8.40 US$4,563
2025-10-02 2025-10-02 PrS Proposed sale

Officer

Officer
755
8.40
US$6,344
755 8.40 US$6,344
2025-10-02 2025-10-02 PrS Proposed sale

Officer

Officer
486
7.09
US$3,447
486 7.09 US$3,447
2025-10-02 2025-10-02 PrS Proposed sale

Officer

Officer
5,958
8.40
US$50,061
5,958 8.40 US$50,061