|
2021-12-02 |
2021-11-30 |
S
Sale
|
Non-Executive Director
|
6,423
-40.8%
92.62
US$2,405,517
|
6,423
-40.8%
|
92.62
|
US$2,405,517
|
|
|
2021-12-02 |
2021-11-30 |
S
Sale
|
Non-Executive Director
|
21,833
-33.4%
459.88
US$2,348,417
|
21,833
-33.4%
|
459.88
|
US$2,348,417
|
|
|
2021-12-02 |
2021-11-30 |
S
Sale
|
Non-Executive Director
|
23,839
+32.7%
487.13
US$4,306,735
|
23,839
+32.7%
|
487.13
|
US$4,306,735
|
|
|
2020-12-07 |
2020-12-04 |
PP
Planned purchase
|
CEO and President
Executive Director
|
8,000
+374.4%
5.77
US$46,160
|
8,000
+374.4%
|
5.77
|
US$46,160
|
|
|
2020-12-07 |
2020-12-04 |
PP
Planned purchase
|
Chief Financial Officer
Officer
|
8,000
+4.4%
5.76
US$46,080
|
8,000
+4.4%
|
5.76
|
US$46,080
|
|
|
2019-12-02 |
2019-12-02 |
B
Purchase
|
AKKARAJU SRINIVAS
Non-Executive Director
|
133,333
+30.1%
7.50
US$999,998
|
133,333
+30.1%
|
7.50
|
US$999,998
|
|
|
2019-10-08 |
2019-10-07 |
S
Sale
|
President and CEO
Executive Director
|
4,004
-5.2%
6.82
US$27,295
|
4,004
-5.2%
|
6.82
|
US$27,295
|
|
|
2019-05-13 |
2019-05-10 |
S
Sale
|
President and CEO
Executive Director
|
1,192
-1.5%
6.11
US$7,283
|
1,192
-1.5%
|
6.11
|
US$7,283
|
|
|
2019-02-05 |
2019-02-01 |
S
Sale
|
President and CEO
Executive Director
|
990
-1.2%
4.14
US$4,099
|
990
-1.2%
|
4.14
|
US$4,099
|
|
|
2019-02-05 |
2019-02-01 |
S
Sale
|
President and CEO
Executive Director
|
969
-1.2%
4.14
US$4,012
|
969
-1.2%
|
4.14
|
US$4,012
|
|
|
2019-02-05 |
2019-02-01 |
S
Sale
|
President and CEO
Executive Director
|
204
-0.2%
4.14
US$845
|
204
-0.2%
|
4.14
|
US$845
|
|
|
2019-02-05 |
2019-02-01 |
S
Sale
|
VP, Finance and PAO
Officer
|
63
-0.6%
4.14
US$261
|
63
-0.6%
|
4.14
|
US$261
|
|
|
2019-02-05 |
2019-02-01 |
S
Sale
|
VP, Finance and PAO
Officer
|
141
-1.3%
4.14
US$584
|
141
-1.3%
|
4.14
|
US$584
|
|
|
2018-12-26 |
2018-12-21 |
S
Sale
|
President and CEO
Executive Director
|
3,484
-4.0%
3.22
US$11,232
|
3,484
-4.0%
|
3.22
|
US$11,232
|
|
|
2018-12-26 |
2018-12-21 |
S
Sale
|
Haas Kevin
VP, Finance and PAO
Officer
|
25
-0.2%
3.23
US$81
|
25
-0.2%
|
3.23
|
US$81
|
|
|
2018-12-26 |
2018-12-21 |
S
Sale
|
Haas Kevin
VP, Finance and PAO
Officer
|
686
-5.8%
3.22
US$2,207
|
686
-5.8%
|
3.22
|
US$2,207
|
|
|
2018-12-19 |
2018-12-17 |
S
Sale
|
Haas Kevin
VP, Finance and PAO
Officer
|
1,164
-8.9%
3.96
US$4,612
|
1,164
-8.9%
|
3.96
|
US$4,612
|
|
|
2018-12-19 |
2018-12-17 |
S
Sale
|
President and CEO
Executive Director
|
11,247
-11.4%
3.96
US$44,561
|
11,247
-11.4%
|
3.96
|
US$44,561
|
|
|
2018-06-19 |
2018-06-15 |
S
Sale
|
Haas Kevin
VP, Finance and PAO
Officer
|
143
-0.2%
2.30
US$329
|
143
-0.2%
|
2.30
|
US$329
|
|
|
2018-06-19 |
2018-06-15 |
S
Sale
|
SVP and Chief Business Officer
Officer
|
612
-0.3%
2.30
US$1,408
|
612
-0.3%
|
2.30
|
US$1,408
|
|
|
2018-06-15 |
2018-06-13 |
B
Purchase
|
AKKARAJU SRINIVAS
|
53,018
+2.0%
2.13
US$112,928
|
53,018
+2.0%
|
2.13
|
US$112,928
|
|
|
2018-06-08 |
2018-06-08 |
B
Purchase
|
AKKARAJU SRINIVAS
|
231,580
+9.7%
2.00
US$463,160
|
231,580
+9.7%
|
2.00
|
US$463,160
|
|
|
2018-06-08 |
2018-06-07 |
B
Purchase
|
AKKARAJU SRINIVAS
|
163,224
+7.3%
1.85
US$301,964
|
163,224
+7.3%
|
1.85
|
US$301,964
|
|
|
2018-06-08 |
2018-06-06 |
B
Purchase
|
AKKARAJU SRINIVAS
|
660,681
+42.0%
1.74
US$1,149,585
|
660,681
+42.0%
|
1.74
|
US$1,149,585
|
|
|
2018-05-23 |
2018-05-22 |
S
Sale
|
Shepard Jay
President and CEO
Executive Director
|
9,232
-1.5%
1.50
US$13,848
|
9,232
-1.5%
|
1.50
|
US$13,848
|
|
|
2018-04-25 |
2018-04-24 |
S
Sale
|
Stout Jay S
SVP, Technical Operations
Officer
|
4,854
-2.5%
1.55
US$7,524
|
4,854
-2.5%
|
1.55
|
US$7,524
|
|
|
2018-03-26 |
2018-03-23 |
S
Sale
|
Chief Commercial Officer
|
4,345
-2.0%
1.75
US$7,604
|
4,345
-2.0%
|
1.75
|
US$7,604
|
|
|
2018-02-12 |
2018-02-08 |
S
Sale
|
Haas Kevin
VP, Finance and PAO
Officer
|
1,599
-2.0%
1.80
US$2,878
|
1,599
-2.0%
|
1.80
|
US$2,878
|
|
|
2018-02-12 |
2018-02-08 |
S
Sale
|
Ward Shane
SVP and General Counsel
Officer
|
4,118
-2.0%
1.80
US$7,412
|
4,118
-2.0%
|
1.80
|
US$7,412
|
|
|
2018-02-12 |
2018-02-08 |
S
Sale
|
SVP and Chief Business Officer
Officer
|
5,355
-2.3%
1.80
US$9,639
|
5,355
-2.3%
|
1.80
|
US$9,639
|
|
|
2018-02-12 |
2018-02-08 |
S
Sale
|
President and CEO
Executive Director
|
14,446
-2.3%
1.80
US$26,003
|
14,446
-2.3%
|
1.80
|
US$26,003
|
|
|
2017-12-05 |
2017-12-05 |
B
Purchase
|
AKKARAJU SRINIVAS
|
42,895
+2.9%
2.00
US$85,790
|
42,895
+2.9%
|
2.00
|
US$85,790
|
|
|
2017-12-05 |
2017-12-04 |
B
Purchase
|
AKKARAJU SRINIVAS
|
513,872
+51.8%
2.21
US$1,135,657
|
513,872
+51.8%
|
2.21
|
US$1,135,657
|
|
|
2017-12-05 |
2017-12-01 |
B
Purchase
|
AKKARAJU SRINIVAS
|
419,700
+73.4%
2.13
US$893,961
|
419,700
+73.4%
|
2.13
|
US$893,961
|
|
|
2017-10-23 |
2017-10-19 |
S
Sale
|
Hislop Colin
Chief Medical Officer
Officer
|
667
-2.7%
2.55
US$1,701
|
667
-2.7%
|
2.55
|
US$1,701
|
|
|
2017-10-23 |
2017-10-19 |
S
Sale
|
COO and CFO
Officer
|
1,326
-0.7%
2.55
US$3,381
|
1,326
-0.7%
|
2.55
|
US$3,381
|
|
|
2017-10-23 |
2017-10-19 |
S
Sale
|
SVP and Chief Business Officer
Officer
|
1,326
-1.0%
2.55
US$3,381
|
1,326
-1.0%
|
2.55
|
US$3,381
|
|
|
2017-10-23 |
2017-10-19 |
S
Sale
|
SVP and General Counsel
Officer
|
776
-0.8%
2.55
US$1,979
|
776
-0.8%
|
2.55
|
US$1,979
|
|
|
2017-09-25 |
2017-09-22 |
S
Sale
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
350,000
-14.3%
3.35
US$1,172,500
|
350,000
-14.3%
|
3.35
|
US$1,172,500
|
|
|
2017-09-25 |
2017-09-22 |
S
Sale
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
500,000
-17.0%
3.27
US$1,633,250
|
500,000
-17.0%
|
3.27
|
US$1,633,250
|
|
|
2017-09-25 |
2017-09-22 |
S
Sale
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
250,000
-7.8%
3.17
US$792,500
|
250,000
-7.8%
|
3.17
|
US$792,500
|
|
|
2017-09-25 |
2017-09-22 |
S
Sale
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
250,000
-7.2%
3.03
US$757,250
|
250,000
-7.2%
|
3.03
|
US$757,250
|
|
|
2017-09-25 |
2017-09-22 |
S
Sale
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
300,000
-8.0%
3.09
US$926,250
|
300,000
-8.0%
|
3.09
|
US$926,250
|
|
|
2017-09-25 |
2017-09-21 |
S
Sale
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
353,421
-8.6%
3.56
US$1,258,143
|
353,421
-8.6%
|
3.56
|
US$1,258,143
|
|
|
2017-09-25 |
2017-09-21 |
S
Sale
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
126,579
-3.0%
3.74
US$473,659
|
126,579
-3.0%
|
3.74
|
US$473,659
|
|
|
2017-06-14 |
2017-06-13 |
S
Sale
|
COO and CFO
|
1,421
-1.3%
16.05
US$22,807
|
1,421
-1.3%
|
16.05
|
US$22,807
|
|
|
2017-06-14 |
2017-06-13 |
S
Sale
|
SVP and Chief Business Officer
|
711
-1.0%
16.05
US$11,412
|
711
-1.0%
|
16.05
|
US$11,412
|
|
|
2017-05-17 |
2017-05-16 |
PlS
Planned sale
|
Brumm Joshua T
COO and CFO
Officer
|
1,263
-1.2%
17.40
US$21,976
|
1,263
-1.2%
|
17.40
|
US$21,976
|
|
|
2017-05-15 |
2017-05-11 |
S
Sale
|
President and CEO
Executive Director
|
9,114
-4.3%
17.50
US$159,495
|
9,114
-4.3%
|
17.50
|
US$159,495
|
|
|
2017-04-20 |
2017-04-19 |
S
Sale
|
SVP and Chief Business Officer
|
1,316
-1.9%
19.85
US$26,123
|
1,316
-1.9%
|
19.85
|
US$26,123
|
|
|
2017-04-05 |
2017-04-04 |
PlS
Planned sale
|
Hislop Colin
Chief Medical Officer
|
35,000
-58.8%
21.20
US$742,000
|
35,000
-58.8%
|
21.20
|
US$742,000
|
|
|
2017-03-28 |
2017-03-24 |
B
Purchase
|
AKKARAJU SRINIVAS
Non-Executive Director
|
571,429
+inf%
12.25
US$7,000,005
|
571,429
+inf%
|
12.25
|
US$7,000,005
|
|
|
2017-03-17 |
2017-03-17 |
S
Sale
|
Malik Shahzad
|
386,367
-19.2%
18.01
US$6,958,470
|
386,367
-19.2%
|
18.01
|
US$6,958,470
|
|
|
2017-03-17 |
2017-03-16 |
S
Sale
|
Malik Shahzad
|
97,303
-4.6%
18.50
US$1,800,106
|
97,303
-4.6%
|
18.50
|
US$1,800,106
|
|
|
2017-03-15 |
2017-03-15 |
S
Sale
|
Ward Shane
SVP and General Counsel
|
776
-2.1%
19.02
US$14,760
|
776
-2.1%
|
19.02
|
US$14,760
|
|
|
2017-03-15 |
2017-03-15 |
S
Sale
|
Malik Shahzad
|
103,122
-4.7%
19.08
US$1,967,568
|
103,122
-4.7%
|
19.08
|
US$1,967,568
|
|
|
2017-03-15 |
2017-03-14 |
S
Sale
|
Ward Shane
SVP and General Counsel
|
1,265
-3.3%
19.00
US$24,035
|
1,265
-3.3%
|
19.00
|
US$24,035
|
|
|
2017-03-15 |
2017-03-14 |
S
Sale
|
Malik Shahzad
|
46,778
-2.1%
19.00
US$888,782
|
46,778
-2.1%
|
19.00
|
US$888,782
|
|
|
2017-03-15 |
2017-03-14 |
S
Sale
|
Malik Shahzad
|
100
-0.0%
19.03
US$1,903
|
100
-0.0%
|
19.03
|
US$1,903
|
|
|
2017-03-15 |
2017-03-13 |
S
Sale
|
Malik Shahzad
|
16,330
-0.7%
19.42
US$317,129
|
16,330
-0.7%
|
19.42
|
US$317,129
|
|
|
2017-02-28 |
2017-02-27 |
PlS
Planned sale
|
Westberg Paul
SVP and Chief Business Officer
|
12,500
-15.2%
22.50
US$281,250
|
12,500
-15.2%
|
22.50
|
US$281,250
|
|
|
2017-02-28 |
2017-02-27 |
PlS
Planned sale
|
Shepard Jay
President and CEO
Executive Director
|
5,166
-2.4%
24.00
US$123,984
|
5,166
-2.4%
|
24.00
|
US$123,984
|
|
|
2017-02-28 |
2017-02-24 |
PlS
Planned sale
|
Brumm Joshua T
COO and CFO
|
5,653
-5.1%
22.05
US$124,649
|
5,653
-5.1%
|
22.05
|
US$124,649
|
|
|
2017-02-28 |
2017-02-24 |
PlS
Planned sale
|
Brumm Joshua T
COO and CFO
|
6,008
-5.1%
21.46
US$128,932
|
6,008
-5.1%
|
21.46
|
US$128,932
|
|
|
2017-02-28 |
2017-02-24 |
PlS
Planned sale
|
Brumm Joshua T
COO and CFO
|
18,339
-13.5%
20.42
US$374,482
|
18,339
-13.5%
|
20.42
|
US$374,482
|
|
|
2017-02-23 |
2017-02-23 |
PlS
Planned sale
|
Westberg Paul
SVP and Chief Business Officer
|
6,590
-8.7%
20.00
US$131,800
|
6,590
-8.7%
|
20.00
|
US$131,800
|
|
|
2017-02-23 |
2017-02-23 |
PlS
Planned sale
|
Shepard Jay
President and CEO
Executive Director
|
8,000
-3.6%
20.00
US$160,000
|
8,000
-3.6%
|
20.00
|
US$160,000
|
|
|
2017-02-23 |
2017-02-21 |
PlS
Planned sale
|
Westberg Paul
SVP and Chief Business Officer
|
5,910
-7.8%
20.00
US$118,200
|
5,910
-7.8%
|
20.00
|
US$118,200
|
|
|
2017-02-23 |
2017-02-21 |
PlS
Planned sale
|
Westberg Paul
SVP and Chief Business Officer
|
12,500
-14.2%
17.50
US$218,750
|
12,500
-14.2%
|
17.50
|
US$218,750
|
|
|
2017-02-23 |
2017-02-21 |
PlS
Planned sale
|
Shepard Jay
President and CEO
Executive Director
|
8,000
-3.6%
18.50
US$148,000
|
8,000
-3.6%
|
18.50
|
US$148,000
|
|
|
2017-02-14 |
2017-02-13 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
59,133
+1.4%
15.51
US$917,425
|
59,133
+1.4%
|
15.51
|
US$917,425
|
|
|
2017-02-14 |
2017-02-10 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
34,883
+0.8%
14.94
US$521,281
|
34,883
+0.8%
|
14.94
|
US$521,281
|
|
|
2017-02-10 |
2017-02-09 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
41,211
+1.0%
14.27
US$587,928
|
41,211
+1.0%
|
14.27
|
US$587,928
|
|
|
2017-02-10 |
2017-02-08 |
B
Purchase
|
PERCEPTIVE ADVISORS LLC
Large shareholder
|
104,612
+2.6%
13.51
US$1,413,319
|
104,612
+2.6%
|
13.51
|
US$1,413,319
|
|
|
2017-02-06 |
2017-02-03 |
PlS
Planned sale
|
Shepard Jay
President and CEO
Executive Director
|
6,719
-3.0%
13.69
US$91,983
|
6,719
-3.0%
|
13.69
|
US$91,983
|
|