|
2019-11-14 |
2019-11-13 |
S
Sale
|
|
11,194
+12.7%
181.68
US$3,673,344
|
11,194
+12.7%
|
181.68
|
US$3,673,344
|
|
|
2019-10-18 |
2019-10-16 |
S
Sale
|
Chief Executive Officer
|
53,210
-21.0%
289.28
US$4,591,302
|
53,210
-21.0%
|
289.28
|
US$4,591,302
|
|
|
2019-10-18 |
2019-10-16 |
S
Sale
|
Chief Executive Officer
|
87,037
+15.5%
289.27
US$4,406,831
|
87,037
+15.5%
|
289.27
|
US$4,406,831
|
|
|
2017-11-22 |
2017-11-20 |
S
Sale
|
JOHNSON & JOHNSON
Large shareholder
|
18,367,346
-100.0%
2.75
US$50,510,202
|
18,367,346
-100.0%
|
2.75
|
US$50,510,202
|
|
|
2016-12-23 |
2016-12-22 |
B
Purchase
|
FISHERMAN JASON S
Non-Executive Director
|
10,000
+25.0%
3.96
US$39,600
|
10,000
+25.0%
|
3.96
|
US$39,600
|
|
|
2016-12-05 |
2016-12-05 |
B
Purchase
|
Fenton Mary Kay
Chief Financial Officer
Officer
|
2,500
+inf%
4.11
US$10,275
|
2,500
+inf%
|
4.11
|
US$10,275
|
|
|
2016-12-05 |
2016-12-02 |
B
Purchase
|
Deshpande Milind
Chief Executive Officer
Executive Director
|
2,500
+inf%
4.06
US$10,150
|
2,500
+inf%
|
4.06
|
US$10,150
|
|
|
2016-12-05 |
2016-12-02 |
B
Purchase
|
Barrish Joel C
Chief Scientific Officer
Officer
|
2,500
+inf%
4.06
US$10,150
|
2,500
+inf%
|
4.06
|
US$10,150
|
|
|
2016-12-05 |
2016-12-02 |
B
Purchase
|
MANNING MARTHA E
EVP, General Counsel
Officer
|
2,500
+inf%
4.09
US$10,225
|
2,500
+inf%
|
4.09
|
US$10,225
|
|
|
2016-12-05 |
2016-12-02 |
B
Purchase
|
Truitt Joseph
Chief Commercial Officer
Officer
|
3,500
+inf%
4.06
US$14,210
|
3,500
+inf%
|
4.06
|
US$14,210
|
|
|
2015-12-30 |
2015-12-30 |
S
Sale
|
Apelian David
Chief Medical Officer
Officer
|
10,000
-100.0%
10.50
US$105,000
|
10,000
-100.0%
|
10.50
|
US$105,000
|
|
|
2015-12-30 |
2015-12-28 |
S
Sale
|
Fenton Mary Kay
Chief Financial Officer
Officer
|
43,500
-100.0%
10.08
US$438,480
|
43,500
-100.0%
|
10.08
|
US$438,480
|
|
|
2015-11-12 |
2015-11-11 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
370
-2.1%
10.31
US$3,815
|
370
-2.1%
|
10.31
|
US$3,815
|
|
|
2015-11-12 |
2015-11-11 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
49,630
-2.1%
10.31
US$511,685
|
49,630
-2.1%
|
10.31
|
US$511,685
|
|
|
2015-11-12 |
2015-11-10 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
1,325
-7.0%
10.43
US$13,820
|
1,325
-7.0%
|
10.43
|
US$13,820
|
|
|
2015-11-12 |
2015-11-10 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
177,749
-7.0%
10.43
US$1,853,922
|
177,749
-7.0%
|
10.43
|
US$1,853,922
|
|
|
2015-11-12 |
2015-11-09 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
2,375
-11.2%
10.01
US$23,774
|
2,375
-11.2%
|
10.01
|
US$23,774
|
|
|
2015-11-12 |
2015-11-09 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
318,551
-11.1%
10.01
US$3,188,696
|
318,551
-11.1%
|
10.01
|
US$3,188,696
|
|
|
2015-09-29 |
2015-09-25 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
69
-0.3%
8.22
US$567
|
69
-0.3%
|
8.22
|
US$567
|
|
|
2015-09-29 |
2015-09-25 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
9,241
-0.3%
8.22
US$75,961
|
9,241
-0.3%
|
8.22
|
US$75,961
|
|
|
2015-08-18 |
2015-08-14 |
S
Sale
|
VITULLO NICOLE
Non-Executive Director
|
37,843
-64.0%
7.51
US$284,201
|
37,843
-64.0%
|
7.51
|
US$284,201
|
|
|
2015-01-23 |
2015-01-23 |
S
Sale
|
Fenton Mary Kay
EVP and CFO
Officer
|
13,125
-100.0%
16.00
US$210,000
|
13,125
-100.0%
|
16.00
|
US$210,000
|
|
|
2015-01-23 |
2015-01-21 |
S
Sale
|
Deshpande Milind
President and CEO
Executive Director
|
100,000
-100.0%
15.00
US$1,500,000
|
100,000
-100.0%
|
15.00
|
US$1,500,000
|
|
|
2014-10-01 |
2014-09-30 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
|
700,000
-9.5%
10.02
US$7,010,500
|
700,000
-9.5%
|
10.02
|
US$7,010,500
|
|
|
2014-10-01 |
2014-09-30 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
|
411,000
-5.3%
10.11
US$4,153,319
|
411,000
-5.3%
|
10.11
|
US$4,153,319
|
|
|
2014-10-01 |
2014-09-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
|
221,014
-2.8%
10.96
US$2,423,264
|
221,014
-2.8%
|
10.96
|
US$2,423,264
|
|
|
2014-09-26 |
2014-09-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
250,000
-3.0%
11.10
US$2,775,000
|
250,000
-3.0%
|
11.10
|
US$2,775,000
|
|
|
2014-09-26 |
2014-09-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
120,000
-1.4%
10.96
US$1,314,600
|
120,000
-1.4%
|
10.96
|
US$1,314,600
|
|
|
2014-09-26 |
2014-09-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
300,000
-3.4%
11.12
US$3,335,190
|
300,000
-3.4%
|
11.12
|
US$3,335,190
|
|
|
2014-09-26 |
2014-09-25 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
250,000
-2.8%
11.06
US$2,765,000
|
250,000
-2.8%
|
11.06
|
US$2,765,000
|
|
|
2014-09-26 |
2014-09-25 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
131,800
-1.5%
11.06
US$1,457,049
|
131,800
-1.5%
|
11.06
|
US$1,457,049
|
|
|
2014-09-26 |
2014-09-25 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
116,186
-1.3%
11.01
US$1,279,696
|
116,186
-1.3%
|
11.01
|
US$1,279,696
|
|
|
2014-09-26 |
2014-09-24 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
500,000
-5.2%
11.28
US$5,640,000
|
500,000
-5.2%
|
11.28
|
US$5,640,000
|
|
|
2014-09-26 |
2014-09-24 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
210,109
-2.1%
11.29
US$2,372,215
|
210,109
-2.1%
|
11.29
|
US$2,372,215
|
|
|
2014-09-26 |
2014-09-24 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
319,100
-3.1%
11.25
US$3,588,280
|
319,100
-3.1%
|
11.25
|
US$3,588,280
|
|
|
2014-09-26 |
2014-09-24 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
175,720
-1.7%
11.24
US$1,974,460
|
175,720
-1.7%
|
11.24
|
US$1,974,460
|
|
|
2014-09-23 |
2014-09-23 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
317,500
-3.0%
11.02
US$3,498,628
|
317,500
-3.0%
|
11.02
|
US$3,498,628
|
|
|
2014-09-23 |
2014-09-23 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
655,239
-5.8%
11.11
US$7,279,574
|
655,239
-5.8%
|
11.11
|
US$7,279,574
|
|
|
2014-09-23 |
2014-09-23 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
11,783
-0.1%
11.10
US$130,808
|
11,783
-0.1%
|
11.10
|
US$130,808
|
|
|
2014-09-23 |
2014-09-22 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
60,549
-0.5%
11.09
US$671,537
|
60,549
-0.5%
|
11.09
|
US$671,537
|
|
|
2014-09-23 |
2014-09-22 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
50,000
-0.4%
11.09
US$554,420
|
50,000
-0.4%
|
11.09
|
US$554,420
|
|
|
2014-09-23 |
2014-09-22 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
335,140
-2.8%
11.08
US$3,714,457
|
335,140
-2.8%
|
11.08
|
US$3,714,457
|
|
|
2014-09-23 |
2014-09-19 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
814,860
-6.4%
11.50
US$9,370,890
|
814,860
-6.4%
|
11.50
|
US$9,370,890
|
|
|
2014-09-23 |
2014-09-19 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
5,900
-0.0%
11.84
US$69,848
|
5,900
-0.0%
|
11.84
|
US$69,848
|
|
|
2014-09-23 |
2014-09-19 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
16,387
-0.1%
11.67
US$191,248
|
16,387
-0.1%
|
11.67
|
US$191,248
|
|
|
2014-09-23 |
2014-09-19 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
327,713
-2.5%
11.65
US$3,818,971
|
327,713
-2.5%
|
11.65
|
US$3,818,971
|
|
|
2014-09-12 |
2014-09-11 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
250,000
-1.9%
12.35
US$3,087,500
|
250,000
-1.9%
|
12.35
|
US$3,087,500
|
|
|
2014-09-12 |
2014-09-11 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
17,357
-0.1%
12.32
US$213,922
|
17,357
-0.1%
|
12.32
|
US$213,922
|
|
|
2014-09-12 |
2014-09-11 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
115,000
-0.9%
12.33
US$1,418,502
|
115,000
-0.9%
|
12.33
|
US$1,418,502
|
|
|
2014-09-12 |
2014-09-11 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
531,352
-3.8%
12.31
US$6,538,446
|
531,352
-3.8%
|
12.31
|
US$6,538,446
|
|
|
2014-09-12 |
2014-09-11 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
83,560
-0.6%
12.62
US$1,054,845
|
83,560
-0.6%
|
12.62
|
US$1,054,845
|
|
|
2014-09-12 |
2014-09-11 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
184,643
-1.3%
12.41
US$2,292,010
|
184,643
-1.3%
|
12.41
|
US$2,292,010
|
|
|
2014-09-12 |
2014-09-10 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
121,943
-0.9%
12.61
US$1,537,677
|
121,943
-0.9%
|
12.61
|
US$1,537,677
|
|
|
2014-09-12 |
2014-09-10 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
69,833
-0.5%
12.63
US$881,907
|
69,833
-0.5%
|
12.63
|
US$881,907
|
|
|
2014-09-12 |
2014-09-10 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
273,017
-1.9%
127,013.00
US$34,676,708,221
|
273,017
-1.9%
|
127,013.00
|
US$34,676,708,221
|
|
|
2014-09-12 |
2014-09-10 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
49,057
-0.3%
12.69
US$622,573
|
49,057
-0.3%
|
12.69
|
US$622,573
|
|
|
2014-09-12 |
2014-09-10 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
8,600
-0.1%
12.73
US$109,443
|
8,600
-0.1%
|
12.73
|
US$109,443
|
|
|
2014-09-02 |
2014-09-02 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
158,655
-1.1%
12.04
US$1,909,921
|
158,655
-1.1%
|
12.04
|
US$1,909,921
|
|
|
2014-09-02 |
2014-09-02 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
103,052
-0.7%
12.01
US$1,237,284
|
103,052
-0.7%
|
12.01
|
US$1,237,284
|
|
|
2014-09-02 |
2014-09-02 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
1,100
-0.0%
11.93
US$13,125
|
1,100
-0.0%
|
11.93
|
US$13,125
|
|
|
2014-09-02 |
2014-08-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
64,000
-0.4%
11.41
US$730,458
|
64,000
-0.4%
|
11.41
|
US$730,458
|
|
|
2014-09-02 |
2014-08-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
217,000
-1.4%
11.40
US$2,473,800
|
217,000
-1.4%
|
11.40
|
US$2,473,800
|
|
|
2014-09-02 |
2014-08-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
46,600
-0.3%
11.45
US$533,337
|
46,600
-0.3%
|
11.45
|
US$533,337
|
|
|
2014-09-02 |
2014-08-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
30,500
-0.2%
11.44
US$348,798
|
30,500
-0.2%
|
11.44
|
US$348,798
|
|
|
2014-09-02 |
2014-08-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
33,960
-0.2%
11.41
US$387,450
|
33,960
-0.2%
|
11.41
|
US$387,450
|
|
|
2014-09-02 |
2014-08-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
2,635
-0.0%
11.42
US$30,095
|
2,635
-0.0%
|
11.42
|
US$30,095
|
|
|
2014-09-02 |
2014-08-29 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
4,150
-0.0%
11.53
US$47,831
|
4,150
-0.0%
|
11.53
|
US$47,831
|
|
|
2014-09-02 |
2014-08-28 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
173,641
-1.1%
11.51
US$1,999,372
|
173,641
-1.1%
|
11.51
|
US$1,999,372
|
|
|
2014-08-27 |
2014-08-27 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
150,100
-1.0%
11.48
US$1,722,518
|
150,100
-1.0%
|
11.48
|
US$1,722,518
|
|
|
2014-08-27 |
2014-08-27 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
116,989
-0.7%
11.75
US$1,374,258
|
116,989
-0.7%
|
11.75
|
US$1,374,258
|
|
|
2014-08-27 |
2014-08-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
312,867
-1.9%
11.77
US$3,681,881
|
312,867
-1.9%
|
11.77
|
US$3,681,881
|
|
|
2014-08-27 |
2014-08-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
150,000
-0.9%
11.78
US$1,767,000
|
150,000
-0.9%
|
11.78
|
US$1,767,000
|
|
|
2014-08-27 |
2014-08-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
250,000
-1.5%
11.80
US$2,948,825
|
250,000
-1.5%
|
11.80
|
US$2,948,825
|
|
|
2014-08-27 |
2014-08-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
52,361
-0.3%
11.16
US$584,218
|
52,361
-0.3%
|
11.16
|
US$584,218
|
|
|
2014-08-27 |
2014-08-26 |
S
Sale
|
RA CAPITAL MANAGEMENT, LLC
Large shareholder
|
1,347,639
-7.5%
11.13
US$14,999,626
|
1,347,639
-7.5%
|
11.13
|
US$14,999,626
|
|