Michael Panzara

Currently holds a position at WAVE Life Sciences Ltd

2.4

2.4

Position	Company	Period
Chief Medical Officer	WAVE Life Sciences Ltd	Nov. 1, 2018 -
Franchise Lead, Neurology	WAVE Life Sciences Ltd	July 1, 2016 - Oct. 1, 2018

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2022-05-06	2022-05-05	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	55,745 +24.8% 480.99 US$4,116,723	55,745 +24.8%	480.99	US$4,116,723
2022-02-18	2022-02-16	WAVE Life Sciences Ltd (WVE)	S Sale	88,387 +39.7% 355.35 US$4,355,244	88,387 +39.7%	355.35	US$4,355,244
2021-02-18	2021-02-16	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	20,482 -30.5% 363.68 US$2,441,831	20,482 -30.5%	363.68	US$2,441,831
2020-02-20	2020-02-18	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	2,981 -7.0% 7.85 US$23,401	2,981 -7.0%	7.85	US$23,401
2019-07-09	2019-07-05	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	445 -1.0% 27.26 US$12,131	445 -1.0%	27.26	US$12,131
2019-07-09	2019-07-05	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	2,613 -5.8% 26.88 US$70,237	2,613 -5.8%	26.88	US$70,237
2019-03-11	2019-03-11	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	7,000 -13.4% 48.00 US$336,000	7,000 -13.4%	48.00	US$336,000
2019-02-21	2019-02-19	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	1,837 -4.7% 36.84 US$67,674	1,837 -4.7%	36.84	US$67,674
2018-02-21	2018-02-16	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	511 -1.3% 52.10 US$26,623	511 -1.3%	52.10	US$26,623
2017-07-13	2017-07-12	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	7,414 -32.6% 16.67 US$123,620	7,414 -32.6%	16.67	US$123,620