ARCH Venture Fund VIII, L.P.

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2022-09-15	2022-09-13	Codiak BioSciences, Inc. (CDAK)	B Purchase	52,691 +39.7% 231.47 US$1,309,612	52,691 +39.7%	231.47	US$1,309,612
2020-10-20	2020-10-16	Codiak BioSciences, Inc. (CDAK)	B Purchase	9,788 +25.1% 354.82 US$1,026,962	9,788 +25.1%	354.82	US$1,026,962
2020-09-22	2020-09-18	Metacrine, Inc. (MTCR)	B Purchase	71,587 -11.9% 295.69 US$4,019,698	71,587 -11.9%	295.69	US$4,019,698
2020-09-22	2020-09-18	Metacrine, Inc. (MTCR)	B Purchase	210,000 +8.2% 13.00 US$2,730,000	210,000 +8.2%	13.00	US$2,730,000