Wagner Heidi L

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2025-12-10	2025-12-08	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	81,131 -11.6% 212.69 US$939,844	81,131 -11.6%	212.69	US$939,844
2025-12-10	2025-12-08	WAVE Life Sciences Ltd (WVE)	PlS Planned sale	67,596 +19.7% 87.72 US$3,947,323	67,596 +19.7%	87.72	US$3,947,323
2025-12-08	2025-12-08	WAVE Life Sciences Ltd (WVE)	PrS Proposed sale	75,289 407.40 US$2,265,053	75,289	407.40	US$2,265,053