Cesano Alessandra

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2025-07-22	2025-07-18	Puma Biotechnology Inc (PBYI)	PlS Planned sale	88,852 +31.5% 307.73 US$124,829	88,852 +31.5%	307.73	US$124,829
2025-07-18	2025-07-18	Puma Biotechnology Inc (PBYI)	PrS Proposed sale	38,743 134.41 US$4,898,489	38,743	134.41	US$4,898,489
2025-06-17	2025-06-13	Puma Biotechnology Inc (PBYI)	PlS Planned sale	40,803 -49.9% 54.12 US$4,049,919	40,803 -49.9%	54.12	US$4,049,919
2025-06-13	2025-06-13	Puma Biotechnology Inc (PBYI)	PrS Proposed sale	12,150 3.40 US$41,285	12,150	3.40	US$41,285