Viswanadhan Krishnan

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2026-04-06	2026-04-02	Agios Pharmaceuticals Inc (AGIO)	PlS Planned sale	14,046 +11.2% 242.33 US$1,899,141	14,046 +11.2%	242.33	US$1,899,141
2026-04-02	2026-04-02	Agios Pharmaceuticals Inc (AGIO)	PrS Proposed sale	79,433 345.98 US$2,381,146	79,433	345.98	US$2,381,146
2026-03-09	2026-03-05	Agios Pharmaceuticals Inc (AGIO)	PlS Planned sale	53,798 +1.1% 13.54 US$4,495,646	53,798 +1.1%	13.54	US$4,495,646
2026-03-05	2026-03-05	Agios Pharmaceuticals Inc (AGIO)	PrS Proposed sale	2,959 29.00 US$85,811	2,959	29.00	US$85,811