Baker Brothers Life Sciences, L.P.

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value
2026-04-23	2026-04-23	Protara Therapeutics Inc (TARA)	PrS Proposed sale	77,487 45.71 US$810,660	77,487	45.71	US$810,660
2026-03-06	2026-03-06	Protara Therapeutics Inc (TARA)	PrS Proposed sale	60,027 457.26 US$1,993,140	60,027	457.26	US$1,993,140
2026-03-04	2026-03-04	Protara Therapeutics Inc (TARA)	PrS Proposed sale	64,341 306.67 US$3,628,620	64,341	306.67	US$3,628,620
2026-02-25	2026-02-25	Protara Therapeutics Inc (TARA)	PrS Proposed sale	947,479 5.81 US$5,501,316	947,479	5.81	US$5,501,316
2026-02-24	2026-02-24	Protara Therapeutics Inc (TARA)	PrS Proposed sale	322,039 6.04 US$1,944,922	322,039	6.04	US$1,944,922
2025-02-28	2025-02-28	BeOne Medicines AG (688235)	PrS Proposed sale	671,976 260.00 US$174,713,760	671,976	260.00	US$174,713,760
2024-12-09	2024-12-09	BeOne Medicines AG (688235)	PrS Proposed sale	950,907 187.27 US$178,074,395	950,907	187.27	US$178,074,395
2023-11-14	2023-11-14	BeOne Medicines AG (688235)	PrS Proposed sale	1,008,660 198.85 US$200,572,041	1,008,660	198.85	US$200,572,041