Garfield Alastair

• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings

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Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other

Notification date	Transaction date	Company	B/S Transaction type	Nb. shares Price Value	Number of shares	Price	Value	Details
2025-07-03	2025-07-02	Rhythm Pharmaceuticals Inc (RYTM)	PlS Planned sale	94,189 +39.8% 94.84 US$2,510,735	94,189 +39.8%	94.84	US$2,510,735
2025-07-03	2025-07-02	Rhythm Pharmaceuticals Inc (RYTM)	PlS Planned sale	50,098 -46.9% 157.43 US$1,562,615	50,098 -46.9%	157.43	US$1,562,615