|
2016-02-23 |
2016-02-19 |
B
Purchase
|
Flynn James E
Large shareholder
|
21,150
+17.2%
416.56
US$4,769,148
|
21,150
+17.2%
|
416.56
|
US$4,769,148
|
|
|
2016-02-23 |
2016-02-19 |
B
Purchase
|
Flynn James E
Large shareholder
|
27,761
-46.8%
377.94
US$3,116,488
|
27,761
-46.8%
|
377.94
|
US$3,116,488
|
|
|
2016-02-16 |
2016-02-12 |
B
Purchase
|
Flynn James E
Large shareholder
|
30,609
+45.5%
295.99
US$4,354,690
|
30,609
+45.5%
|
295.99
|
US$4,354,690
|
|
|
2016-02-16 |
2016-02-12 |
B
Purchase
|
Flynn James E
Large shareholder
|
15,499
+0.7%
3.92
US$60,803
|
15,499
+0.7%
|
3.92
|
US$60,803
|
|
|
2016-02-16 |
2016-02-11 |
B
Purchase
|
Flynn James E
Large shareholder
|
1,157,189
+74.3%
3.76
US$4,349,642
|
1,157,189
+74.3%
|
3.76
|
US$4,349,642
|
|
|
2016-02-16 |
2016-02-11 |
B
Purchase
|
Flynn James E
Large shareholder
|
909,221
+74.3%
3.76
US$3,417,580
|
909,221
+74.3%
|
3.76
|
US$3,417,580
|
|
|
2016-02-16 |
2016-02-11 |
B
Purchase
|
Flynn James E
Large shareholder
|
1,557,991
+inf%
3.96
US$6,166,840
|
1,557,991
+inf%
|
3.96
|
US$6,166,840
|
|
|
2016-02-16 |
2016-02-11 |
B
Purchase
|
Flynn James E
Large shareholder
|
1,224,136
+inf%
3.96
US$4,845,375
|
1,224,136
+inf%
|
3.96
|
US$4,845,375
|
|
|
2016-01-22 |
2016-01-20 |
B
Purchase
|
Flynn James E
Large shareholder
|
346,417
+5.5%
4.09
US$1,418,404
|
346,417
+5.5%
|
4.09
|
US$1,418,404
|
|
|
2015-11-13 |
2015-11-11 |
S
Sale
|
Freund John Gordon
Non-Executive Director
|
909
-0.2%
6.68
US$6,074
|
909
-0.2%
|
6.68
|
US$6,074
|
|
|
2015-07-15 |
2015-07-15 |
PlS
Planned sale
|
Barrett Ronald W
Chief Executive Officer
Executive Director
|
12,500
-5.8%
7.20
US$90,000
|
12,500
-5.8%
|
7.20
|
US$90,000
|
|
|
2015-05-12 |
2015-05-11 |
B
Purchase
|
WIERENGA WENDALL
Non-Executive Director
|
5,000
+20.8%
5.63
US$28,169
|
5,000
+20.8%
|
5.63
|
US$28,169
|
|
|
2014-12-12 |
2014-12-10 |
S
Sale
|
RIEFLIN WILLIAM JL
Non-Executive Director
|
2,500
-10.3%
8.49
US$21,225
|
2,500
-10.3%
|
8.49
|
US$21,225
|
|
|
2014-12-12 |
2014-12-10 |
S
Sale
|
RIEFLIN WILLIAM JL
Non-Executive Director
|
5,592
-18.8%
8.49
US$47,476
|
5,592
-18.8%
|
8.49
|
US$47,476
|
|
|
2014-12-12 |
2014-12-10 |
S
Sale
|
RIEFLIN WILLIAM JL
Non-Executive Director
|
2,918
-8.9%
8.49
US$24,774
|
2,918
-8.9%
|
8.49
|
US$24,774
|
|
|
2014-12-10 |
2014-12-08 |
S
Sale
|
Barrett Ronald W
Chief Executive Officer
Executive Director
|
3,000
-1.8%
8.40
US$25,200
|
3,000
-1.8%
|
8.40
|
US$25,200
|
|
|
2014-12-10 |
2014-12-08 |
S
Sale
|
Barrett Ronald W
Chief Executive Officer
Executive Director
|
2,000
-1.2%
8.35
US$16,700
|
2,000
-1.2%
|
8.35
|
US$16,700
|
|
|
2014-12-10 |
2014-12-08 |
S
Sale
|
Barrett Ronald W
Chief Executive Officer
Executive Director
|
1,015
-0.6%
8.32
US$8,445
|
1,015
-0.6%
|
8.32
|
US$8,445
|
|
|
2014-12-10 |
2014-12-08 |
S
Sale
|
BATES GREGORY T
SVP, Regulatory Affairs & QA
Officer
|
9,581
-31.6%
8.35
US$80,001
|
9,581
-31.6%
|
8.35
|
US$80,001
|
|
|
2014-12-10 |
2014-12-08 |
S
Sale
|
BATES GREGORY T
SVP, Regulatory Affairs & QA
Officer
|
4,585
-18.1%
8.35
US$38,285
|
4,585
-18.1%
|
8.35
|
US$38,285
|
|
|
2014-12-10 |
2014-12-08 |
S
Sale
|
Barrett Ronald W
Chief Executive Officer
Executive Director
|
1,000
-0.6%
8.30
US$8,303
|
1,000
-0.6%
|
8.30
|
US$8,303
|
|
|
2014-12-08 |
2014-12-05 |
S
Sale
|
Bosko Gianna M
SVP, CLO and Secretary
Officer
|
20,000
-20.6%
8.40
US$168,000
|
20,000
-20.6%
|
8.40
|
US$168,000
|
|
|
2014-12-08 |
2014-12-05 |
S
Sale
|
Bosko Gianna M
SVP, CLO and Secretary
Officer
|
21,348
-21.7%
8.45
US$180,418
|
21,348
-21.7%
|
8.45
|
US$180,418
|
|
|
2014-12-08 |
2014-12-04 |
S
Sale
|
Bosko Gianna M
SVP, CLO and Secretary
Officer
|
7,399
-8.8%
8.50
US$62,897
|
7,399
-8.8%
|
8.50
|
US$62,897
|
|
|
2014-12-08 |
2014-12-04 |
S
Sale
|
Bosko Gianna M
SVP, CLO and Secretary
Officer
|
11,253
-12.7%
8.50
US$95,658
|
11,253
-12.7%
|
8.50
|
US$95,658
|
|
|
2014-09-10 |
2014-09-09 |
S
Sale
|
BATES GREGORY T
SVP, Regulatory Affairs & QA
Officer
|
5,612
-21.3%
5.26
US$29,519
|
5,612
-21.3%
|
5.26
|
US$29,519
|
|
|
2014-06-04 |
2014-06-03 |
B
Purchase
|
Freund John Gordon
Non-Executive Director
|
12,500
+123.4%
3.93
US$49,164
|
12,500
+123.4%
|
3.93
|
US$49,164
|
|
|
2014-05-27 |
2014-05-27 |
B
Purchase
|
FRIEDMAN CATHY
Non-Executive Director
|
2,600
+inf%
3.92
US$10,179
|
2,600
+inf%
|
3.92
|
US$10,179
|
|
|
2014-05-27 |
2014-05-27 |
B
Purchase
|
WIERENGA WENDALL
Non-Executive Director
|
10,000
+71.4%
3.99
US$39,900
|
10,000
+71.4%
|
3.99
|
US$39,900
|
|
|
2014-05-27 |
2014-05-27 |
B
Purchase
|
FENTON DENNIS M
Non-Executive Director
|
3,000
+30.0%
4.02
US$12,046
|
3,000
+30.0%
|
4.02
|
US$12,046
|
|
|
2014-05-28 |
2014-05-23 |
B
Purchase
|
Barrett Ronald W
Chief Executive Officer
Executive Director
|
2,600
+1.5%
3.75
US$9,745
|
2,600
+1.5%
|
3.75
|
US$9,745
|
|
|
2014-05-27 |
2014-05-23 |
B
Purchase
|
Freund John Gordon
Non-Executive Director
|
9,500
+81.2%
3.72
US$35,354
|
9,500
+81.2%
|
3.72
|
US$35,354
|
|
|
2014-05-27 |
2014-05-23 |
B
Purchase
|
MARIO ERNEST
Non-Executive Director
|
30,000
+55.8%
3.73
US$111,978
|
30,000
+55.8%
|
3.73
|
US$111,978
|
|
|
2014-05-27 |
2014-05-22 |
B
Purchase
|
Freund John Gordon
Non-Executive Director
|
5,500
+88.7%
3.75
US$20,623
|
5,500
+88.7%
|
3.75
|
US$20,623
|
|
|
2014-05-16 |
2014-05-15 |
PlS
Planned sale
|
BERNS PAUL L
Non-Executive Director
|
2,500
-33.3%
3.66
US$9,150
|
2,500
-33.3%
|
3.66
|
US$9,150
|
|
|
2013-06-17 |
2013-06-14 |
S
Sale
|
BATES GREGORY T
SVP, Regulatory Affairs & QA
Officer
|
7,500
-31.2%
5.35
US$40,125
|
7,500
-31.2%
|
5.35
|
US$40,125
|
|
|
2013-05-23 |
2013-05-22 |
B
Purchase
|
MARIO ERNEST
Non-Executive Director
|
20,000
+200.0%
5.49
US$109,800
|
20,000
+200.0%
|
5.49
|
US$109,800
|
|
|
2012-08-09 |
2012-08-09 |
B
Purchase
|
MARIO ERNEST
Non-Executive Director
|
10,000
+inf%
8.50
US$84,983
|
10,000
+inf%
|
8.50
|
US$84,983
|
|
|
2011-12-16 |
2011-12-16 |
B
Purchase
|
RIEFLIN WILLIAM JL
Non-Executive Director
|
10,000
+3.7%
3.86
US$38,580
|
10,000
+3.7%
|
3.86
|
US$38,580
|
|
|
2011-11-22 |
2011-11-21 |
B
Purchase
|
RIEFLIN WILLIAM JL
Non-Executive Director
|
10,000
+3.8%
4.44
US$44,413
|
10,000
+3.8%
|
4.44
|
US$44,413
|
|
|
2011-11-09 |
2011-11-07 |
B
Purchase
|
RIEFLIN WILLIAM JL
Non-Executive Director
|
5,000
+2.0%
5.49
US$27,452
|
5,000
+2.0%
|
5.49
|
US$27,452
|
|
|
2010-11-12 |
2010-11-12 |
B
Purchase
|
FENTON DENNIS M
Non-Executive Director
|
300
+30.0%
7.86
US$2,358
|
300
+30.0%
|
7.86
|
US$2,358
|
|
|
2010-11-12 |
2010-11-12 |
B
Purchase
|
FENTON DENNIS M
Non-Executive Director
|
35
+3.6%
7.87
US$275
|
35
+3.6%
|
7.87
|
US$275
|
|
|
2010-11-12 |
2010-11-12 |
B
Purchase
|
FENTON DENNIS M
Non-Executive Director
|
100
+11.6%
7.92
US$792
|
100
+11.6%
|
7.92
|
US$792
|
|
|
2010-11-12 |
2010-11-12 |
B
Purchase
|
FENTON DENNIS M
Non-Executive Director
|
100
+13.1%
7.93
US$793
|
100
+13.1%
|
7.93
|
US$793
|
|
|
2010-11-12 |
2010-11-12 |
B
Purchase
|
FENTON DENNIS M
Non-Executive Director
|
765
+inf%
7.94
US$6,071
|
765
+inf%
|
7.94
|
US$6,071
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
18.47
US$1,847
|
100
-0.7%
|
18.47
|
US$1,847
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
18.43
US$1,843
|
100
-0.7%
|
18.43
|
US$1,843
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
18.58
US$1,858
|
100
-0.7%
|
18.58
|
US$1,858
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
18.61
US$1,861
|
100
-0.7%
|
18.61
|
US$1,861
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
18.52
US$1,852
|
100
-0.7%
|
18.52
|
US$1,852
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.50
US$1,850
|
100
-0.6%
|
18.50
|
US$1,850
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.46
US$1,846
|
100
-0.6%
|
18.46
|
US$1,846
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.39
US$1,839
|
100
-0.6%
|
18.39
|
US$1,839
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.32
US$1,832
|
100
-0.6%
|
18.32
|
US$1,832
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.30
US$1,830
|
100
-0.6%
|
18.30
|
US$1,830
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
200
-1.2%
18.36
US$3,672
|
200
-1.2%
|
18.36
|
US$3,672
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
200
-1.2%
18.49
US$3,698
|
200
-1.2%
|
18.49
|
US$3,698
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.57
US$1,857
|
100
-0.6%
|
18.57
|
US$1,857
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
200
-1.2%
18.60
US$3,720
|
200
-1.2%
|
18.60
|
US$3,720
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
30
-0.2%
18.79
US$564
|
30
-0.2%
|
18.79
|
US$564
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
2
-0.0%
18.80
US$38
|
2
-0.0%
|
18.80
|
US$38
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
68
-0.4%
18.81
US$1,279
|
68
-0.4%
|
18.81
|
US$1,279
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.68
US$1,868
|
100
-0.6%
|
18.68
|
US$1,868
|
|
|
2010-02-04 |
2010-02-01 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.6%
18.72
US$1,872
|
100
-0.6%
|
18.72
|
US$1,872
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
19.20
US$1,920
|
100
-0.7%
|
19.20
|
US$1,920
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
19.17
US$1,917
|
100
-0.7%
|
19.17
|
US$1,917
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
19.52
US$1,952
|
100
-0.7%
|
19.52
|
US$1,952
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
19.36
US$1,936
|
100
-0.7%
|
19.36
|
US$1,936
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
32
-0.2%
19.26
US$616
|
32
-0.2%
|
19.26
|
US$616
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
268
-1.8%
19.25
US$5,159
|
268
-1.8%
|
19.25
|
US$5,159
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
200
-1.4%
19.28
US$3,856
|
200
-1.4%
|
19.28
|
US$3,856
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
19.23
US$1,923
|
100
-0.7%
|
19.23
|
US$1,923
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
200
-1.3%
19.22
US$3,844
|
200
-1.3%
|
19.22
|
US$3,844
|
|
|
2010-01-06 |
2010-01-04 |
PlS
Planned sale
|
Cundy Kenneth C
SVP, Preclinical Development
Officer
|
100
-0.7%
19.27
US$1,927
|
100
-0.7%
|
19.27
|
US$1,927
|
|