IL Biotechnology & Medical Research

Sol Gel Technologies Ltd (SLGL)

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Sol Gel Technologies witnessed significant insider trading activity recently, with Opaleye Management Inc. executing fifteen consecutive buy transactions totaling approximately $3.87 million. These acquisitions occurred following the August 2026 earnings report, which showed a positive EPS surprise. Despite this accumulation, the stock price has declined 16.4% over the past ninety days.
Ticker: SLGL Exchange: NAS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Sol Gel Technologies Ltd. Upgrade to see score, net flow, insiders and the full signal context.

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Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
130.44
Quantity 22,933 +19.3%
Value US$1,496,889
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
44.12
Quantity 33,568 +44.7%
Value US$102,255
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
372.58
Quantity 11,874 -17.6%
Value US$3,497,994
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
68.74
Quantity 3,390 +0.6%
Value US$233,030
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
68.98
Quantity 2,100 +0.4%
Value US$144,858
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
69.10
Quantity 217 +0.0%
Value US$14,995
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
68.24
Quantity 5,000 +1.0%
Value US$341,175
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
68.81
Quantity 5,000 +1.0%
Value US$344,050
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
68.42
Quantity 20,113 +4.1%
Value US$1,376,137
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
71.40
Quantity 10,000 +2.1%
Value US$713,969
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
71.50
Quantity 951 +0.2%
Value US$67,996
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
73.43
Quantity 920 +0.2%
Value US$67,556
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
73.89
Quantity 775 +0.2%
Value US$57,263
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
73.95
Quantity 229 +0.0%
Value US$16,935
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
71.97
Quantity 1,400 +0.3%
Value US$100,759
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
71.97
Quantity 1,400 +0.3%
Value US$100,759
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
64.43
Quantity 1,563 +0.3%
Value US$100,712
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
66.87
Quantity 1,937 +0.4%
Value US$129,527
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
67.98
Quantity 1,500 +0.3%
Value US$101,975
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
72.00
Quantity 5,000 +50.0%
Value US$360,000
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
72.00
Quantity 34,665 +7.7%
Value US$2,495,880
Yosef Itzik Officer Officer
Transaction date
Proposed sale
Price
88.70
Quantity 142
Value US$12,595
Yosef Itzik Officer Officer
Transaction date
Proposed sale
Price
87.63
Quantity 1,556
Value US$136,352
Yosef Itzik Officer Officer
Transaction date
Proposed sale
Price
83.98
Quantity 1,170
Value US$98,257
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
63.00
Quantity 291 +0.1%
Value US$18,333
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
55.98
Quantity 1,151 +0.3%
Value US$64,434
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
56.57
Quantity 2,173 +0.5%
Value US$122,922
Yosef Itzik Officer Officer
Transaction date
Proposed sale
Price
62.94
Quantity 713
Value US$44,876
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
41.92
Quantity 2,394 +0.5%
Value US$100,348
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
41.99
Quantity 22,497 +5.3%
Value US$944,744
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
41.99
Quantity 35,169 +9.1%
Value US$1,476,627
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
41.85
Quantity 8,638 +2.3%
Value US$361,534
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
41.68
Quantity 1,626 +0.4%
Value US$67,765
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
41.66
Quantity 260 +0.1%
Value US$10,832
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
41.15
Quantity 1,019 +0.3%
Value US$41,936
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
40.37
Quantity 2,735 +0.7%
Value US$110,412
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
37.81
Quantity 2,524 +0.7%
Value US$95,443
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
37.37
Quantity 4,340 +1.2%
Value US$162,167
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
40.00
Quantity 943 +0.3%
Value US$37,720
3.4
Opaleye Management Inc. Large shareholder
Transaction date
Purchase
Price
35.83
Quantity 5,784 +1.6%
Value US$207,244
1.4
Krindel Yaffa Director Non-Executive Director
Transaction date
Proposed sale
Price
2.02
Quantity 600
Value US$1,212
1.4
Krindel Yaffa Director Non-Executive Director
Transaction date
Proposed sale
Price
2.05
Quantity 400
Value US$820
1.4
Krindel Yaffa Director Non-Executive Director
Transaction date
Proposed sale
Price
2.01
Quantity 1,200
Value US$2,412
Mamlok Gilad Officer Officer
Transaction date
Proposed sale
Price
3.71
Quantity 5,000
Value US$18,550
Seri Levy Alon Officer Officer
Transaction date
Proposed sale
Price
3.06
Quantity 55,389
Value US$169,490
Mamlok Gilad Officer Officer
Transaction date
Proposed sale
Price
3.61
Quantity 5,421
Value US$19,591
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-09-14 2026-09-11 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
22,933 +19.3%
130.44
US$1,496,889 		22,933 +19.3% 130.44 US$1,496,889
2026-09-14 2026-09-10 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
33,568 +44.7%
44.12
US$102,255 		33,568 +44.7% 44.12 US$102,255
2026-09-09 2026-09-09 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
11,874 -17.6%
372.58
US$3,497,994 		11,874 -17.6% 372.58 US$3,497,994
2026-09-09 2026-09-08 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
471 +0.1%
69.37
US$32,673 		471 +0.1% 69.37 US$32,673
2026-09-09 2026-09-08 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
3,390 +0.6%
68.74
US$233,030 		3,390 +0.6% 68.74 US$233,030
2026-09-09 2026-09-04 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
2,100 +0.4%
68.98
US$144,858 		2,100 +0.4% 68.98 US$144,858
2026-09-09 2026-09-04 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
918 +0.2%
69.52
US$63,819 		918 +0.2% 69.52 US$63,819
2026-09-03 2026-09-02 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
900 +0.2%
68.95
US$62,054 		900 +0.2% 68.95 US$62,054
2026-09-03 2026-09-01 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
783 +0.1%
69.52
US$54,434 		783 +0.1% 69.52 US$54,434
2026-08-31 2026-08-31 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
217 +0.0%
69.10
US$14,995 		217 +0.0% 69.10 US$14,995
2026-08-31 2026-08-31 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
5,000 +1.0%
68.24
US$341,175 		5,000 +1.0% 68.24 US$341,175
2026-08-31 2026-08-28 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
5,000 +1.0%
68.81
US$344,050 		5,000 +1.0% 68.81 US$344,050
2026-08-31 2026-08-28 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
20,113 +4.1%
68.42
US$1,376,137 		20,113 +4.1% 68.42 US$1,376,137
2026-08-31 2026-08-28 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
10,000 +2.1%
71.40
US$713,969 		10,000 +2.1% 71.40 US$713,969
2026-08-14 2026-08-12 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
951 +0.2%
71.50
US$67,996 		951 +0.2% 71.50 US$67,996
2026-07-15 2026-07-14 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
920 +0.2%
73.43
US$67,556 		920 +0.2% 73.43 US$67,556
2026-07-15 2026-07-13 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
775 +0.2%
73.89
US$57,263 		775 +0.2% 73.89 US$57,263
2026-07-10 2026-07-10 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
229 +0.0%
73.95
US$16,935 		229 +0.0% 73.95 US$16,935
2026-07-10 2026-07-08 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
300 +0.1%
73.69
US$22,107 		300 +0.1% 73.69 US$22,107
2026-07-02 2026-07-02 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,400 +0.3%
71.97
US$100,759 		1,400 +0.3% 71.97 US$100,759
2026-07-02 2026-07-02 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,400 +0.3%
71.97
US$100,759 		1,400 +0.3% 71.97 US$100,759
2026-07-02 2026-07-01 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
312 +0.1%
71.99
US$22,461 		312 +0.1% 71.99 US$22,461
2026-05-22 2026-05-20 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,563 +0.3%
64.43
US$100,712 		1,563 +0.3% 64.43 US$100,712
2026-05-14 2026-05-13 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,937 +0.4%
66.87
US$129,527 		1,937 +0.4% 66.87 US$129,527
2026-05-14 2026-05-12 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,500 +0.3%
67.98
US$101,975 		1,500 +0.3% 67.98 US$101,975
2026-03-24 2026-03-24 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
5,000 +50.0%
72.00
US$360,000 		5,000 +50.0% 72.00 US$360,000
2026-03-24 2026-03-24 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
34,665 +7.7%
72.00
US$2,495,880 		34,665 +7.7% 72.00 US$2,495,880
2026-03-12 2026-03-11 PrS Proposed sale
Yosef Itzik

Officer

Officer
142
88.70
US$12,595 		142 88.70 US$12,595
2026-02-26 2026-02-25 PrS Proposed sale
Yosef Itzik

Officer

Officer
1,556
87.63
US$136,352 		1,556 87.63 US$136,352
2026-02-24 2026-02-23 PrS Proposed sale
Yosef Itzik

Officer

Officer
1,170
83.98
US$98,257 		1,170 83.98 US$98,257
2026-02-18 2026-02-13 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
291 +0.1%
63.00
US$18,333 		291 +0.1% 63.00 US$18,333
2026-02-04 2026-02-02 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
100 +0.0%
58.00
US$5,800 		100 +0.0% 58.00 US$5,800
2026-01-29 2026-01-27 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
100 +0.0%
57.05
US$5,705 		100 +0.0% 57.05 US$5,705
2026-01-23 2026-01-23 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,151 +0.3%
55.98
US$64,434 		1,151 +0.3% 55.98 US$64,434
2026-01-23 2026-01-22 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
2,173 +0.5%
56.57
US$122,922 		2,173 +0.5% 56.57 US$122,922
2026-01-15 2026-01-14 PrS Proposed sale
Yosef Itzik

Officer

Officer
713
62.94
US$44,876 		713 62.94 US$44,876
2026-01-06 2026-01-05 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
198 +0.0%
42.98
US$8,510 		198 +0.0% 42.98 US$8,510
2026-01-06 2026-01-02 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
2,394 +0.5%
41.92
US$100,348 		2,394 +0.5% 41.92 US$100,348
2025-12-31 2025-12-31 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
22,497 +5.3%
41.99
US$944,744 		22,497 +5.3% 41.99 US$944,744
2025-12-31 2025-12-30 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
35,169 +9.1%
41.99
US$1,476,627 		35,169 +9.1% 41.99 US$1,476,627
2025-12-31 2025-12-29 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
8,638 +2.3%
41.85
US$361,534 		8,638 +2.3% 41.85 US$361,534
2025-12-29 2025-12-26 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,626 +0.4%
41.68
US$67,765 		1,626 +0.4% 41.68 US$67,765
2025-12-29 2025-12-23 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
260 +0.1%
41.66
US$10,832 		260 +0.1% 41.66 US$10,832
2025-12-29 2025-12-22 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
1,019 +0.3%
41.15
US$41,936 		1,019 +0.3% 41.15 US$41,936
2025-12-19 2025-12-17 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
2,735 +0.7%
40.37
US$110,412 		2,735 +0.7% 40.37 US$110,412
2025-12-16 2025-12-12 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
87 +0.0%
40.00
US$3,480 		87 +0.0% 40.00 US$3,480
2025-12-09 2025-12-08 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
300 +0.1%
39.78
US$11,932 		300 +0.1% 39.78 US$11,932
2025-12-09 2025-12-05 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
444 +0.1%
39.50
US$17,537 		444 +0.1% 39.50 US$17,537
2025-12-03 2025-12-03 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
2,524 +0.7%
37.81
US$95,443 		2,524 +0.7% 37.81 US$95,443
2025-12-03 2025-12-01 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
4,340 +1.2%
37.37
US$162,167 		4,340 +1.2% 37.37 US$162,167
2025-11-26 2025-11-26 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
943 +0.3%
40.00
US$37,720 		943 +0.3% 40.00 US$37,720
2025-11-26 2025-11-24 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
6 +0.0%
35.50
US$213 		6 +0.0% 35.50 US$213
2025-11-21 2025-11-20 B Purchase
3.4
Opaleye Management Inc.
Large shareholder
5,784 +1.6%
35.83
US$207,244 		5,784 +1.6% 35.83 US$207,244
2023-09-28 2023-09-27 PrS Proposed sale
1.4
Krindel Yaffa

Director

Non-Executive Director
600
2.02
US$1,212 		600 2.02 US$1,212
2023-09-27 2023-09-26 PrS Proposed sale
1.4
Krindel Yaffa

Director

Non-Executive Director
400
2.05
US$820 		400 2.05 US$820
2023-09-26 2023-09-22 PrS Proposed sale
1.4
Krindel Yaffa

Director

Non-Executive Director
1,200
2.01
US$2,412 		1,200 2.01 US$2,412
2023-07-24 2023-07-21 PrS Proposed sale
Mamlok Gilad

Officer

Officer
5,000
3.71
US$18,550 		5,000 3.71 US$18,550
2023-06-27 2023-06-27 PrS Proposed sale
Seri Levy Alon

Officer

Officer
55,389
3.06
US$169,490 		55,389 3.06 US$169,490
2023-05-02 2023-05-02 PrS Proposed sale
Mamlok Gilad

Officer

Officer
5,421
3.61
US$19,591 		5,421 3.61 US$19,591
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