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Ticker: SIEN Exchange: NSM


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Purchase Sale Planned purchase Planned sale Net purchase Net sale
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PS: Planned sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Total value Details
Aug. 12, 2021 Aug. 12, 2021 B Purchase

Schmidt Andrew C

Chief Financial Officer

Officer
1,449 +3.0%
6.89
9,976 USD
1,449 +3.0% 6.89 9,976 USD
April 8, 2021 April 6, 2021 S Sale

MILLER VALERIE J

VP, Controller and Interim CFO

Officer
1,508 -2.3%
7.13
10,751 USD
1,508 -2.3% 7.13 10,751 USD
June 11, 2019 June 7, 2019 B Purchase

Sullivan Keith J

20,869 +11.4%
5.75
119,997 USD
20,869 +11.4% 5.75 119,997 USD
June 11, 2019 June 7, 2019 B Purchase

Little Paul Sean

Chief Financial Officer

17,391 +22.4%
5.75
99,998 USD
17,391 +22.4% 5.75 99,998 USD
June 11, 2019 June 7, 2019 B Purchase

OBOYLE KEVIN C

8,696 +19.3%
5.75
50,002 USD
8,696 +19.3% 5.75 50,002 USD
Nov. 8, 2018 Nov. 6, 2018 PS Planned sale

Haines Timothy

Non-Executive Director
81,137 -3.3%
21.60
1,752,559 USD
81,137 -3.3% 21.60 1,752,559 USD
Nov. 8, 2018 Nov. 6, 2018 PS Planned sale

Haines Timothy

Non-Executive Director
8,514 -0.3%
21.13
179,901 USD
8,514 -0.3% 21.13 179,901 USD
Sept. 5, 2018 Aug. 31, 2018 S Sale

Nugent Jeffrey M

Chairman of the Board and CEO

Executive Director
1,852 -0.6%
24.90
46,115 USD
1,852 -0.6% 24.90 46,115 USD
May 9, 2018 May 7, 2018 B Purchase

Haines Timothy

Non-Executive Director
281,482 +12.8%
13.50
3,800,007 USD
281,482 +12.8% 13.50 3,800,007 USD
May 9, 2018 May 7, 2018 B Purchase

Abingworth LLP

281,482 +12.8%
13.50
3,800,007 USD
281,482 +12.8% 13.50 3,800,007 USD
May 9, 2018 May 7, 2018 B Purchase

SCHAISON PHILIPPE

Non-Executive Director
7,407 +24.4%
13.50
99,995 USD
7,407 +24.4% 13.50 99,995 USD
May 9, 2018 May 7, 2018 B Purchase

Williams Patrick F.

Chief Financial Officer & SVP

Officer
7,408 +14.8%
13.50
100,008 USD
7,408 +14.8% 13.50 100,008 USD
May 9, 2018 May 7, 2018 B Purchase

Nugent Jeffrey M

Chairman of the Board and CEO

Executive Director
1,852 +0.6%
13.50
25,002 USD
1,852 +0.6% 13.50 25,002 USD
May 9, 2018 May 7, 2018 B Purchase

Sullivan Keith J

Non-Executive Director
7,407 +6.5%
13.50
99,995 USD
7,407 +6.5% 13.50 99,995 USD
May 9, 2018 May 7, 2018 B Purchase

GREER R SCOTT

Non-Executive Director
11,111 +26.7%
13.50
149,999 USD
11,111 +26.7% 13.50 149,999 USD
May 9, 2018 May 7, 2018 B Purchase

OBOYLE KEVIN C

Non-Executive Director
7,407 +23.5%
13.50
99,995 USD
7,407 +23.5% 13.50 99,995 USD
Oct. 13, 2015 Oct. 12, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
2,785 -14.0%
5.98
16,654 USD
2,785 -14.0% 5.98 16,654 USD
Oct. 13, 2015 Oct. 12, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
285,106 -13.9%
5.98
1,704,934 USD
285,106 -13.9% 5.98 1,704,934 USD
Oct. 9, 2015 Oct. 9, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
2,041 -9.3%
7.03
14,348 USD
2,041 -9.3% 7.03 14,348 USD
Oct. 9, 2015 Oct. 9, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
210,668 -9.3%
7.03
1,480,996 USD
210,668 -9.3% 7.03 1,480,996 USD
Oct. 9, 2015 Oct. 8, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
3,837 -14.9%
7.24
27,780 USD
3,837 -14.9% 7.24 27,780 USD
Oct. 9, 2015 Oct. 8, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
396,163 -14.9%
7.24
2,868,220 USD
396,163 -14.9% 7.24 2,868,220 USD
Oct. 9, 2015 Oct. 7, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
454 -1.7%
7.36
3,341 USD
454 -1.7% 7.36 3,341 USD
Oct. 9, 2015 Oct. 7, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
53,446 -2.0%
7.36
393,363 USD
53,446 -2.0% 7.36 393,363 USD
Oct. 6, 2015 Oct. 6, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
59 -0.2%
7.80
460 USD
59 -0.2% 7.80 460 USD
Oct. 6, 2015 Oct. 6, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
6,941 -0.3%
7.80
54,140 USD
6,941 -0.3% 7.80 54,140 USD
Oct. 6, 2015 Oct. 5, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
1,163 -4.2%
8.19
9,525 USD
1,163 -4.2% 8.19 9,525 USD
Oct. 6, 2015 Oct. 5, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
136,937 -4.8%
8.19
1,121,514 USD
136,937 -4.8% 8.19 1,121,514 USD
Oct. 6, 2015 Oct. 2, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
403 -1.4%
10.34
4,167 USD
403 -1.4% 10.34 4,167 USD
Oct. 6, 2015 Oct. 2, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
47,497 -1.6%
10.34
491,119 USD
47,497 -1.6% 10.34 491,119 USD
Oct. 1, 2015 Oct. 1, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
400 -1.4%
10.34
4,136 USD
400 -1.4% 10.34 4,136 USD
Oct. 1, 2015 Oct. 1, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
47,100 -1.6%
10.34
487,014 USD
47,100 -1.6% 10.34 487,014 USD
Oct. 1, 2015 Sept. 30, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
369 -1.3%
10.17
3,753 USD
369 -1.3% 10.17 3,753 USD
Oct. 1, 2015 Sept. 30, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
43,471 -1.5%
10.17
442,100 USD
43,471 -1.5% 10.17 442,100 USD
Oct. 1, 2015 Sept. 29, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
89 -0.3%
10.08
897 USD
89 -0.3% 10.08 897 USD
Oct. 1, 2015 Sept. 29, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
10,469 -0.3%
10.08
105,528 USD
10,469 -0.3% 10.08 105,528 USD
Sept. 28, 2015 Sept. 28, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
89 -0.3%
10.30
917 USD
89 -0.3% 10.30 917 USD
Sept. 28, 2015 Sept. 28, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
10,513 -0.3%
10.30
108,284 USD
10,513 -0.3% 10.30 108,284 USD
Sept. 28, 2015 Sept. 25, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
311 -1.1%
11.07
3,443 USD
311 -1.1% 11.07 3,443 USD
Sept. 28, 2015 Sept. 25, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
66,489 -2.2%
11.07
736,033 USD
66,489 -2.2% 11.07 736,033 USD
Sept. 28, 2015 Sept. 25, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
800 -2.7%
10.07
8,056 USD
800 -2.7% 10.07 8,056 USD
Sept. 28, 2015 Sept. 25, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
64,400 -2.0%
10.07
648,508 USD
64,400 -2.0% 10.07 648,508 USD
Sept. 28, 2015 Sept. 24, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
8,152 -0.3%
11.00
89,672 USD
8,152 -0.3% 11.00 89,672 USD
Sept. 28, 2015 Sept. 24, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
148 -0.5%
11.00
1,628 USD
148 -0.5% 11.00 1,628 USD
Sept. 28, 2015 Sept. 24, 2015 S Sale

ORBIMED ADVISORS LLC

Major owner
6 -0.0%
9.78
59 USD
6 -0.0% 9.78 59 USD
Nov. 3, 2014 Oct. 29, 2014 B Purchase

Haines Timothy

Non-Executive Director Major owner
495,000 +29.0%
15.00
7,425,000 USD
495,000 +29.0% 15.00 7,425,000 USD
Oct. 31, 2014 Oct. 29, 2014 B Purchase

Abingworth LLP

Major owner
495,000 +29.0%
15.00
7,425,000 USD
495,000 +29.0% 15.00 7,425,000 USD