|
2023-03-10 |
2023-03-10 |
B
Purchase
|
Large shareholder
|
47,866
-45.6%
17.25
US$1,269,024
|
47,866
-45.6%
|
17.25
|
US$1,269,024
|
|
|
2023-01-20 |
2023-01-18 |
S
Sale
|
Chief Medical Officer
Officer
|
7,275
-39.8%
418.47
US$3,234,658
|
7,275
-39.8%
|
418.47
|
US$3,234,658
|
|
|
2023-01-20 |
2023-01-18 |
S
Sale
|
Chief Commercial Officer
Officer
|
87,492
-2.9%
479.54
US$3,028,788
|
87,492
-2.9%
|
479.54
|
US$3,028,788
|
|
|
2023-01-20 |
2023-01-18 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
1,272
-0.4%
26.89
US$34,204
|
1,272
-0.4%
|
26.89
|
US$34,204
|
|
|
2023-01-20 |
2023-01-18 |
S
Sale
|
Principal Executive Officer
Executive Director
|
8,037
-1.9%
26.89
US$216,115
|
8,037
-1.9%
|
26.89
|
US$216,115
|
|
|
2023-01-05 |
2023-01-04 |
S
Sale
|
Chief Medical Officer
Officer
|
2,251
-0.9%
26.90
US$60,552
|
2,251
-0.9%
|
26.90
|
US$60,552
|
|
|
2023-01-05 |
2023-01-04 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
2,779
-0.8%
26.90
US$74,755
|
2,779
-0.8%
|
26.90
|
US$74,755
|
|
|
2022-12-20 |
2022-12-16 |
S
Sale
|
Principal Financial Officer
Officer
|
2,241
-1.1%
26.75
US$59,947
|
2,241
-1.1%
|
26.75
|
US$59,947
|
|
|
2022-10-20 |
2022-10-18 |
S
Sale
|
Principal Executive Officer
Executive Director
|
11,156
-2.6%
25.20
US$281,131
|
11,156
-2.6%
|
25.20
|
US$281,131
|
|
|
2022-10-20 |
2022-10-18 |
S
Sale
|
Chief Medical Officer
Officer
|
1,604
-0.6%
25.20
US$40,421
|
1,604
-0.6%
|
25.20
|
US$40,421
|
|
|
2022-10-20 |
2022-10-18 |
S
Sale
|
Chief Commercial Officer
Officer
|
1,703
-1.0%
25.20
US$42,916
|
1,703
-1.0%
|
25.20
|
US$42,916
|
|
|
2022-10-20 |
2022-10-18 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
1,933
-0.5%
25.20
US$48,712
|
1,933
-0.5%
|
25.20
|
US$48,712
|
|
|
2022-10-06 |
2022-10-04 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
3,679
-1.0%
24.40
US$89,768
|
3,679
-1.0%
|
24.40
|
US$89,768
|
|
|
2022-10-06 |
2022-10-04 |
S
Sale
|
Chief Medical Officer
Officer
|
2,738
-1.1%
24.40
US$66,807
|
2,738
-1.1%
|
24.40
|
US$66,807
|
|
|
2022-09-20 |
2022-09-16 |
S
Sale
|
Principal Financial Officer
Officer
|
9,243
-4.3%
18.86
US$174,323
|
9,243
-4.3%
|
18.86
|
US$174,323
|
|
|
2022-08-16 |
2022-08-15 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
31,214
-7.9%
18.23
US$569,031
|
31,214
-7.9%
|
18.23
|
US$569,031
|
|
|
2022-07-20 |
2022-07-18 |
S
Sale
|
Chief Medical Officer
Officer
|
1,606
-0.6%
12.87
US$20,669
|
1,606
-0.6%
|
12.87
|
US$20,669
|
|
|
2022-07-20 |
2022-07-18 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
1,935
-0.7%
12.87
US$24,903
|
1,935
-0.7%
|
12.87
|
US$24,903
|
|
|
2022-07-20 |
2022-07-18 |
S
Sale
|
Chief Commercial Officer
Officer
|
1,704
-1.0%
12.87
US$21,930
|
1,704
-1.0%
|
12.87
|
US$21,930
|
|
|
2022-07-20 |
2022-07-18 |
S
Sale
|
Principal Executive Officer
Executive Director
|
11,164
-2.5%
12.87
US$143,681
|
11,164
-2.5%
|
12.87
|
US$143,681
|
|
|
2022-07-08 |
2022-07-06 |
S
Sale
|
Chief Medical Officer
Officer
|
2,755
-1.1%
13.40
US$36,917
|
2,755
-1.1%
|
13.40
|
US$36,917
|
|
|
2022-07-08 |
2022-07-06 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
3,702
-1.3%
13.40
US$49,607
|
3,702
-1.3%
|
13.40
|
US$49,607
|
|
|
2022-06-01 |
2022-05-27 |
S
Sale
|
Chief Medical Officer
Officer
|
1,382
-0.5%
10.07
US$13,917
|
1,382
-0.5%
|
10.07
|
US$13,917
|
|
|
2022-04-21 |
2022-04-19 |
S
Sale
|
Chief Medical Officer
Officer
|
4,632
-1.7%
10.45
US$48,404
|
4,632
-1.7%
|
10.45
|
US$48,404
|
|
|
2022-04-21 |
2022-04-19 |
S
Sale
|
Chief Commercial Officer
Officer
|
7,049
-3.9%
10.45
US$73,662
|
7,049
-3.9%
|
10.45
|
US$73,662
|
|
|
2022-04-21 |
2022-04-19 |
S
Sale
|
Principal Executive Officer
Executive Director
|
24,594
-5.2%
10.45
US$257,007
|
24,594
-5.2%
|
10.45
|
US$257,007
|
|
|
2022-04-21 |
2022-04-19 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
8,002
-2.8%
10.45
US$83,621
|
8,002
-2.8%
|
10.45
|
US$83,621
|
|
|
2022-04-07 |
2022-04-05 |
S
Sale
|
Chief Medical Officer
Officer
|
1,922
-1.2%
13.78
US$26,485
|
1,922
-1.2%
|
13.78
|
US$26,485
|
|
|
2022-04-07 |
2022-04-05 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
2,436
-1.4%
13.78
US$33,568
|
2,436
-1.4%
|
13.78
|
US$33,568
|
|
|
2022-03-03 |
2022-03-01 |
S
Sale
|
Chief Medical Officer
Officer
|
1,362
-0.8%
13.35
US$18,183
|
1,362
-0.8%
|
13.35
|
US$18,183
|
|
|
2022-01-21 |
2022-01-19 |
S
Sale
|
Principal Executive Officer
Executive Director
|
19,882
-5.6%
14.68
US$291,868
|
19,882
-5.6%
|
14.68
|
US$291,868
|
|
|
2022-01-06 |
2022-01-04 |
S
Sale
|
Chief Medical Officer
Officer
|
2,271
-1.4%
16.27
US$36,949
|
2,271
-1.4%
|
16.27
|
US$36,949
|
|
|
2022-01-06 |
2022-01-04 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
4,475
-2.5%
16.27
US$72,808
|
4,475
-2.5%
|
16.27
|
US$72,808
|
|
|
2021-12-01 |
2021-11-29 |
S
Sale
|
Chief Medical Officer
Officer
|
1,978
-1.2%
19.30
US$38,175
|
1,978
-1.2%
|
19.30
|
US$38,175
|
|
|
2021-11-05 |
2021-11-04 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
3,100
-1.8%
24.02
US$74,462
|
3,100
-1.8%
|
24.02
|
US$74,462
|
|
|
2021-11-05 |
2021-11-03 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
700
-0.4%
24.00
US$16,800
|
700
-0.4%
|
24.00
|
US$16,800
|
|
|
2021-10-07 |
2021-10-05 |
S
Sale
|
Chief Medical Officer
Officer
|
2,738
-1.6%
21.62
US$59,196
|
2,738
-1.6%
|
21.62
|
US$59,196
|
|
|
2021-10-07 |
2021-10-05 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
6,671
-3.6%
21.62
US$144,227
|
6,671
-3.6%
|
21.62
|
US$144,227
|
|
|
2021-09-29 |
2021-09-27 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
7,000
-3.9%
24.32
US$170,240
|
7,000
-3.9%
|
24.32
|
US$170,240
|
|
|
2021-09-28 |
2021-09-27 |
PP
Planned purchase
|
Large shareholder
|
2,232
+0.0%
24.86
US$55,486
|
2,232
+0.0%
|
24.86
|
US$55,486
|
|
|
2021-09-28 |
2021-09-27 |
PP
Planned purchase
|
Large shareholder
|
45,768
+0.1%
24.19
US$1,106,904
|
45,768
+0.1%
|
24.19
|
US$1,106,904
|
|
|
2021-09-28 |
2021-09-24 |
PP
Planned purchase
|
Large shareholder
|
36,000
+0.1%
23.40
US$842,548
|
36,000
+0.1%
|
23.40
|
US$842,548
|
|
|
2021-09-14 |
2021-09-13 |
PP
Planned purchase
|
Large shareholder
|
30,028
+0.1%
23.91
US$717,990
|
30,028
+0.1%
|
23.91
|
US$717,990
|
|
|
2021-09-14 |
2021-09-13 |
PP
Planned purchase
|
Large shareholder
|
53,150
+0.1%
23.09
US$1,227,058
|
53,150
+0.1%
|
23.09
|
US$1,227,058
|
|
|
2021-09-14 |
2021-09-10 |
PP
Planned purchase
|
Large shareholder
|
30,000
+0.1%
25.11
US$753,390
|
30,000
+0.1%
|
25.11
|
US$753,390
|
|
|
2021-09-13 |
2021-09-09 |
PlS
Planned sale
|
Non-Executive Director
|
4,850
-100.0%
25.58
US$124,063
|
4,850
-100.0%
|
25.58
|
US$124,063
|
|
|
2021-09-01 |
2021-08-31 |
PP
Planned purchase
|
Large shareholder
|
39,000
+0.1%
24.28
US$946,885
|
39,000
+0.1%
|
24.28
|
US$946,885
|
|
|
2021-09-01 |
2021-08-30 |
PP
Planned purchase
|
Large shareholder
|
70,000
+0.1%
23.92
US$1,674,099
|
70,000
+0.1%
|
23.92
|
US$1,674,099
|
|
|
2021-08-30 |
2021-08-27 |
PP
Planned purchase
|
Large shareholder
|
37,038
+0.1%
23.17
US$858,252
|
37,038
+0.1%
|
23.17
|
US$858,252
|
|
|
2021-08-30 |
2021-08-26 |
PP
Planned purchase
|
Large shareholder
|
40,000
+0.1%
22.67
US$906,912
|
40,000
+0.1%
|
22.67
|
US$906,912
|
|
|
2021-08-20 |
2021-08-19 |
PP
Planned purchase
|
Large shareholder
|
46,792
+0.1%
21.51
US$1,006,421
|
46,792
+0.1%
|
21.51
|
US$1,006,421
|
|
|
2021-08-20 |
2021-08-18 |
PP
Planned purchase
|
Large shareholder
|
17,116
+0.0%
21.45
US$367,092
|
17,116
+0.0%
|
21.45
|
US$367,092
|
|
|
2021-06-02 |
2021-05-28 |
S
Sale
|
Chief Medical Officer
Officer
|
1,783
-1.0%
24.00
US$42,792
|
1,783
-1.0%
|
24.00
|
US$42,792
|
|
|
2021-06-02 |
2021-05-28 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
1,300
-0.7%
24.00
US$31,200
|
1,300
-0.7%
|
24.00
|
US$31,200
|
|
|
2021-05-28 |
2021-05-26 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
12,700
-6.7%
24.23
US$307,721
|
12,700
-6.7%
|
24.23
|
US$307,721
|
|
|
2021-04-08 |
2021-04-06 |
S
Sale
|
Chief Medical Officer
Officer
|
8,114
-6.0%
18.63
US$151,164
|
8,114
-6.0%
|
18.63
|
US$151,164
|
|
|
2021-04-08 |
2021-04-06 |
S
Sale
|
General Counsel & Corp. Secy.
Officer
|
10,862
-7.4%
18.62
US$202,250
|
10,862
-7.4%
|
18.62
|
US$202,250
|
|
|
2021-03-23 |
2021-03-19 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
7,000
-4.9%
24.17
US$169,190
|
7,000
-4.9%
|
24.17
|
US$169,190
|
|
|
2021-03-17 |
2021-03-15 |
PlS
Planned sale
|
General Counsel & Corp. Secy.
Officer
|
30,000
-17.1%
25.07
US$752,013
|
30,000
-17.1%
|
25.07
|
US$752,013
|
|
|
2021-03-03 |
2021-03-01 |
S
Sale
|
Chief Medical Officer
Officer
|
1,513
-1.1%
22.55
US$34,118
|
1,513
-1.1%
|
22.55
|
US$34,118
|
|
|
2021-02-18 |
2021-02-16 |
PlS
Planned sale
|
Principal Fin'l & Accounting
Officer
|
750
-0.5%
21.40
US$16,050
|
750
-0.5%
|
21.40
|
US$16,050
|
|
|
2021-02-01 |
2021-01-28 |
PlS
Planned sale
|
Principal Fin'l & Accounting
Officer
|
300
-0.2%
24.00
US$7,200
|
300
-0.2%
|
24.00
|
US$7,200
|
|
|
2021-01-20 |
2021-01-15 |
PlS
Planned sale
|
Principal Fin'l & Accounting
Officer
|
750
-0.5%
21.50
US$16,125
|
750
-0.5%
|
21.50
|
US$16,125
|
|
|
2020-12-30 |
2020-12-28 |
PlS
Planned sale
|
Principal Fin'l & Accounting
Officer
|
11,800
-6.7%
30.00
US$354,000
|
11,800
-6.7%
|
30.00
|
US$354,000
|
|
|
2020-12-22 |
2020-12-18 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
2,000
-1.4%
26.00
US$52,000
|
2,000
-1.4%
|
26.00
|
US$52,000
|
|
|
2020-12-22 |
2020-12-18 |
PlS
Planned sale
|
General Counsel & Corp. Secy.
Officer
|
300
-0.2%
26.24
US$7,871
|
300
-0.2%
|
26.24
|
US$7,871
|
|
|
2020-12-22 |
2020-12-18 |
PlS
Planned sale
|
General Counsel & Corp. Secy.
Officer
|
9,700
-6.2%
25.38
US$246,183
|
9,700
-6.2%
|
25.38
|
US$246,183
|
|
|
2020-12-17 |
2020-12-15 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
3,467
-2.5%
24.18
US$83,837
|
3,467
-2.5%
|
24.18
|
US$83,837
|
|
|
2020-12-17 |
2020-12-15 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
3,533
-2.5%
23.66
US$83,589
|
3,533
-2.5%
|
23.66
|
US$83,589
|
|
|
2020-12-17 |
2020-12-15 |
PlS
Planned sale
|
Principal Fin'l & Accounting
Officer
|
670
-0.4%
24.45
US$16,383
|
670
-0.4%
|
24.45
|
US$16,383
|
|
|
2020-12-17 |
2020-12-15 |
PlS
Planned sale
|
Principal Fin'l & Accounting
Officer
|
380
-0.2%
23.63
US$8,980
|
380
-0.2%
|
23.63
|
US$8,980
|
|
|
2020-12-14 |
2020-12-10 |
PlS
Planned sale
|
Chief Medical Officer
Officer
|
10,000
-6.8%
26.04
US$260,362
|
10,000
-6.8%
|
26.04
|
US$260,362
|
|
|
2020-12-11 |
2020-12-10 |
PlS
Planned sale
|
General Counsel & Corp. Secy.
Officer
|
19,400
-11.7%
25.20
US$488,783
|
19,400
-11.7%
|
25.20
|
US$488,783
|
|
|
2020-12-11 |
2020-12-09 |
PlS
Planned sale
|
General Counsel & Corp. Secy.
Officer
|
600
-0.4%
25.08
US$15,049
|
600
-0.4%
|
25.08
|
US$15,049
|
|
|
2020-12-02 |
2020-11-30 |
PlS
Planned sale
|
Principal Fin'l & Accounting
Officer
|
1,500
-0.9%
24.00
US$36,000
|
1,500
-0.9%
|
24.00
|
US$36,000
|
|