|
2026-01-30 |
2026-01-28 |
PlS
Planned sale
|
EVP, Ops & Clinical Research
Officer
|
19,830
-19.8%
259.31
US$1,831,668
|
19,830
-19.8%
|
259.31
|
US$1,831,668
|
|
|
2026-01-30 |
2026-01-28 |
PlS
Planned sale
|
EVP, Ops & Clinical Research
Officer
|
44,643
+38.6%
438.16
US$733,296
|
44,643
+38.6%
|
438.16
|
US$733,296
|
|
|
2026-01-30 |
2026-01-28 |
PlS
Planned sale
|
EVP, Ops & Clinical Research
Officer
|
65,906
-22.3%
480.96
US$2,195,474
|
65,906
-22.3%
|
480.96
|
US$2,195,474
|
|
|
2026-01-28 |
2026-01-28 |
PrS
Proposed sale
|
Officer
Officer
|
18,680
136.81
US$2,555,567
|
18,680
|
136.81
|
US$2,555,567
|
|
|
2025-12-11 |
2025-12-11 |
PrS
Proposed sale
|
Former Affiliate
|
17,118
142.00
US$2,430,756
|
17,118
|
142.00
|
US$2,430,756
|
|
|
2025-11-28 |
2025-11-28 |
PrS
Proposed sale
|
Officer
Officer
|
3,229
142.79
US$461,069
|
3,229
|
142.79
|
US$461,069
|
|
|
2025-09-29 |
2025-09-29 |
PrS
Proposed sale
|
Former Affiliate
|
25,061
141.80
US$3,553,637
|
25,061
|
141.80
|
US$3,553,637
|
|
|
2025-09-26 |
2025-09-26 |
PrS
Proposed sale
|
Former Affiliate
|
50,000
141.88
US$7,093,910
|
50,000
|
141.88
|
US$7,093,910
|
|
|
2025-09-23 |
2025-09-23 |
PrS
Proposed sale
|
Former Affiliate
|
25,000
140.76
US$3,518,983
|
25,000
|
140.76
|
US$3,518,983
|
|
|
2025-08-14 |
2025-08-13 |
B
Purchase
|
Chairman of the Board
Non-Executive Director
|
100
+1.4%
155.25
US$15,525
|
100
+1.4%
|
155.25
|
US$15,525
|
|
|
2025-08-14 |
2025-08-12 |
B
Purchase
|
Chairman of the Board
Non-Executive Director
|
100
+1.4%
150.35
US$15,035
|
100
+1.4%
|
150.35
|
US$15,035
|
|
|
2025-08-12 |
2025-08-11 |
B
Purchase
|
Non-Executive Director
|
3,000
+167.6%
145.98
US$437,940
|
3,000
+167.6%
|
145.98
|
US$437,940
|
|
|
2025-05-13 |
2025-05-13 |
PrS
Proposed sale
|
Former Director
Non-Executive Director
|
16,443
164.00
US$2,696,652
|
16,443
|
164.00
|
US$2,696,652
|
|
|
2025-05-14 |
2025-05-12 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
525
-2.1%
164.96
US$86,605
|
525
-2.1%
|
164.96
|
US$86,605
|
|
|
2025-05-14 |
2025-05-12 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
5,594
-18.5%
163.51
US$914,664
|
5,594
-18.5%
|
163.51
|
US$914,664
|
|
|
2025-05-14 |
2025-05-12 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
3,881
-11.4%
162.72
US$631,512
|
3,881
-11.4%
|
162.72
|
US$631,512
|
|
|
2025-05-12 |
2025-05-12 |
PrS
Proposed sale
|
Officer
Officer
|
10,000
163.24
US$1,632,386
|
10,000
|
163.24
|
US$1,632,386
|
|
|
2025-05-12 |
2025-05-12 |
PrS
Proposed sale
|
Former Affiliate
|
3,455
163.42
US$564,616
|
3,455
|
163.42
|
US$564,616
|
|
|
2025-04-24 |
2025-04-24 |
PrS
Proposed sale
|
Former Officer
Officer
|
26,300
162.95
US$4,285,475
|
26,300
|
162.95
|
US$4,285,475
|
|
|
2025-03-14 |
2025-03-14 |
PrS
Proposed sale
|
Director
Non-Executive Director
|
2,053
166.13
US$341,068
|
2,053
|
166.13
|
US$341,068
|
|
|
2025-03-14 |
2025-03-14 |
PlS
Planned sale
|
Non-Executive Director
|
2,053
-11.0%
166.13
US$341,068
|
2,053
-11.0%
|
166.13
|
US$341,068
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
1,716
-6.6%
171.76
US$294,740
|
1,716
-6.6%
|
171.76
|
US$294,740
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
6,965
-21.2%
170.86
US$1,190,040
|
6,965
-21.2%
|
170.86
|
US$1,190,040
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
1,761
-5.1%
169.37
US$298,261
|
1,761
-5.1%
|
169.37
|
US$298,261
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
1,700
-4.7%
167.97
US$285,549
|
1,700
-4.7%
|
167.97
|
US$285,549
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
1,436
-3.8%
166.71
US$239,396
|
1,436
-3.8%
|
166.71
|
US$239,396
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
10,087
-21.1%
166.03
US$1,674,745
|
10,087
-21.1%
|
166.03
|
US$1,674,745
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
3,935
-7.6%
165.18
US$649,983
|
3,935
-7.6%
|
165.18
|
US$649,983
|
|
|
2025-03-12 |
2025-03-10 |
PlS
Planned sale
|
Chief Operating Officer
Officer
|
2,400
-4.4%
163.28
US$391,872
|
2,400
-4.4%
|
163.28
|
US$391,872
|
|
|
2025-03-10 |
2025-03-10 |
PrS
Proposed sale
|
Officer
Officer
|
30,000
167.48
US$5,024,549
|
30,000
|
167.48
|
US$5,024,549
|
|
|
2025-03-03 |
2025-03-03 |
PrS
Proposed sale
|
Officer
Officer
|
49,000
191.13
US$9,365,578
|
49,000
|
191.13
|
US$9,365,578
|
|
|
2025-03-03 |
2025-02-28 |
PrS
Proposed sale
|
Former Affiliate
|
36,537
187.67
US$6,856,889
|
36,537
|
187.67
|
US$6,856,889
|
|
|
2025-01-07 |
2025-01-07 |
PrS
Proposed sale
|
Former Affiliate
|
302,165
165.65
US$50,052,375
|
302,165
|
165.65
|
US$50,052,375
|
|
|
2024-12-16 |
2024-12-16 |
PrS
Proposed sale
|
Former Affiliate
|
15,072
176.73
US$2,663,664
|
15,072
|
176.73
|
US$2,663,664
|
|
|
2024-04-30 |
2024-04-26 |
PlS
Planned sale
|
Non-Executive Director
|
40,000
-84.4%
136.17
US$5,446,616
|
40,000
-84.4%
|
136.17
|
US$5,446,616
|
|
|
2024-04-26 |
2024-04-26 |
PrS
Proposed sale
|
Director
Non-Executive Director
|
40,000
136.17
US$5,446,615
|
40,000
|
136.17
|
US$5,446,615
|
|
|
2023-05-30 |
2023-05-25 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
500
+0.1%
158.19
US$79,094
|
500
+0.1%
|
158.19
|
US$79,094
|
|
|
2023-05-30 |
2023-05-25 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
2,265
+0.6%
157.53
US$356,814
|
2,265
+0.6%
|
157.53
|
US$356,814
|
|
|
2023-05-30 |
2023-05-25 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
3,600
+1.0%
156.79
US$564,435
|
3,600
+1.0%
|
156.79
|
US$564,435
|
|
|
2022-12-19 |
2022-12-15 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
1,541
+3.4%
146.23
US$225,340
|
1,541
+3.4%
|
146.23
|
US$225,340
|
|
|
2022-12-19 |
2022-12-15 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
2,039
+4.7%
145.22
US$296,097
|
2,039
+4.7%
|
145.22
|
US$296,097
|
|
|
2022-12-19 |
2022-12-15 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
2,397
+5.9%
144.19
US$345,616
|
2,397
+5.9%
|
144.19
|
US$345,616
|
|
|
2022-12-19 |
2022-12-15 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
1,063
+2.7%
143.27
US$152,300
|
1,063
+2.7%
|
143.27
|
US$152,300
|
|
|
2022-11-15 |
2022-11-14 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
300
+0.8%
124.99
US$37,497
|
300
+0.8%
|
124.99
|
US$37,497
|
|
|
2022-11-15 |
2022-11-14 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
16,537
+72.1%
124.45
US$2,057,952
|
16,537
+72.1%
|
124.45
|
US$2,057,952
|
|
|
2022-11-15 |
2022-11-14 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
15,157
+194.7%
123.48
US$1,871,561
|
15,157
+194.7%
|
123.48
|
US$1,871,561
|
|
|
2022-11-15 |
2022-11-11 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
1,100
+16.5%
130.56
US$143,613
|
1,100
+16.5%
|
130.56
|
US$143,613
|
|
|
2022-11-15 |
2022-11-11 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
2,514
+60.3%
129.90
US$326,572
|
2,514
+60.3%
|
129.90
|
US$326,572
|
|
|
2022-11-15 |
2022-11-11 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
2,969
+247.2%
128.86
US$382,586
|
2,969
+247.2%
|
128.86
|
US$382,586
|
|
|
2022-11-15 |
2022-11-11 |
B
Purchase
|
CEO and Chairman of the Board
Executive Director
|
1,201
+inf%
127.80
US$153,484
|
1,201
+inf%
|
127.80
|
US$153,484
|
|
|
2022-01-26 |
2022-01-24 |
PlS
Planned sale
|
Non-Executive Director
|
600
-25.5%
214.80
US$128,880
|
600
-25.5%
|
214.80
|
US$128,880
|
|
|
2022-01-20 |
2022-01-18 |
PlS
Planned sale
|
Non-Executive Director
|
600
-20.3%
228.70
US$137,220
|
600
-20.3%
|
228.70
|
US$137,220
|
|
|
2022-01-12 |
2022-01-10 |
PlS
Planned sale
|
Non-Executive Director
|
600
-16.9%
250.01
US$150,006
|
600
-16.9%
|
250.01
|
US$150,006
|
|
|
2021-12-08 |
2021-12-06 |
PlS
Planned sale
|
EVP, Bus Dev
Officer
|
3,000
-20.6%
275.47
US$826,410
|
3,000
-20.6%
|
275.47
|
US$826,410
|
|
|
2021-11-19 |
2021-11-19 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
8,416
-1.6%
300.83
US$2,531,807
|
8,416
-1.6%
|
300.83
|
US$2,531,807
|
|
|
2021-11-19 |
2021-11-18 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
20,399
-3.8%
300.05
US$6,120,761
|
20,399
-3.8%
|
300.05
|
US$6,120,761
|
|
|
2021-11-19 |
2021-11-17 |
PlS
Planned sale
|
CEO and Chairman of the Board
Executive Director
|
32,597
-5.7%
300.54
US$9,796,614
|
32,597
-5.7%
|
300.54
|
US$9,796,614
|
|
|
2021-11-16 |
2021-11-16 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
2,440
-0.4%
300.01
US$732,036
|
2,440
-0.4%
|
300.01
|
US$732,036
|
|
|
2021-11-16 |
2021-11-15 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
27,599
-4.6%
301.36
US$8,317,265
|
27,599
-4.6%
|
301.36
|
US$8,317,265
|
|
|
2021-11-16 |
2021-11-12 |
PlS
Planned sale
|
EVP & Chief Financial Officer
Officer
|
3,700
-25.4%
298.00
US$1,102,600
|
3,700
-25.4%
|
298.00
|
US$1,102,600
|
|
|
2021-11-16 |
2021-11-12 |
PlS
Planned sale
|
CEO and Chairman of the Board
Executive Director
|
8,549
-1.4%
300.03
US$2,564,970
|
8,549
-1.4%
|
300.03
|
US$2,564,970
|
|
|
2021-11-05 |
2021-11-04 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
4,173
-0.7%
290.16
US$1,210,854
|
4,173
-0.7%
|
290.16
|
US$1,210,854
|
|
|
2021-11-05 |
2021-11-03 |
PlS
Planned sale
|
CEO and Chairman of the Board
Executive Director
|
200
-0.0%
290.17
US$58,035
|
200
-0.0%
|
290.17
|
US$58,035
|
|
|
2021-11-02 |
2021-11-02 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
15,223
-2.4%
291.46
US$4,436,826
|
15,223
-2.4%
|
291.46
|
US$4,436,826
|
|
|
2021-11-02 |
2021-11-02 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
8,223
-100.0%
291.46
US$2,396,638
|
8,223
-100.0%
|
291.46
|
US$2,396,638
|
|
|
2021-11-02 |
2021-11-01 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
3,429
-29.4%
290.08
US$994,675
|
3,429
-29.4%
|
290.08
|
US$994,675
|
|
|
2021-11-02 |
2021-10-29 |
PlS
Planned sale
|
CEO and Chairman of the Board
Executive Director
|
18,967
-61.9%
290.97
US$5,518,779
|
18,967
-61.9%
|
290.97
|
US$5,518,779
|
|
|
2021-10-28 |
2021-10-27 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
19,853
-25.5%
290.55
US$5,768,192
|
19,853
-25.5%
|
290.55
|
US$5,768,192
|
|
|
2021-10-28 |
2021-10-26 |
S
Sale
|
CEO and Chairman of the Board
Executive Director
|
27,332
-47.2%
291.23
US$7,959,904
|
27,332
-47.2%
|
291.23
|
US$7,959,904
|
|
|
2021-10-28 |
2021-10-26 |
PlS
Planned sale
|
CEO and Chairman of the Board
Executive Director
|
2,600
-3.2%
290.10
US$754,266
|
2,600
-3.2%
|
290.10
|
US$754,266
|
|
|
2021-05-04 |
2021-05-03 |
PP
Planned purchase
|
EVP, GEN COUNSEL & CORP SEC
Officer
|
500
+2.2%
230.00
US$115,000
|
500
+2.2%
|
230.00
|
US$115,000
|
|
|
2021-05-04 |
2021-04-30 |
PP
Planned purchase
|
EVP, GEN COUNSEL & CORP SEC
Officer
|
500
+2.3%
233.24
US$116,620
|
500
+2.3%
|
233.24
|
US$116,620
|
|
|
2021-04-12 |
2021-04-08 |
PlS
Planned sale
|
EVP & Chief Financial Officer
Officer
|
2,087
-12.5%
239.00
US$498,793
|
2,087
-12.5%
|
239.00
|
US$498,793
|
|
|
2021-01-14 |
2021-01-12 |
PlS
Planned sale
|
CEO and Chairman of the Board
Executive Director
|
3,403
-4.1%
280.32
US$953,943
|
3,403
-4.1%
|
280.32
|
US$953,943
|
|
|
2021-01-13 |
2021-01-11 |
PlS
Planned sale
|
Non-Executive Director
|
10,000
-69.9%
279.74
US$2,797,412
|
10,000
-69.9%
|
279.74
|
US$2,797,412
|
|