United States Biotechnology & Medical Research

MacroGenics Inc (MGNX)

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The most recent insider trading activity occurred on August 20, 2025, with a BUY transaction by HEIDEN WILLIAM K. Prior to this, significant SELL transactions were noted in February 2025 and April 2024, primarily involving PLANNED_SALE and PROPOSED_SALE types by Peters Jeffrey Stuart and Risser Eric Blasius.
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Ticker: MGNX Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
HEIDEN WILLIAM K
1 purchase — total 73,755 USD
Buy 20 Aug 2025
Value US$2,071,369.15 | Price 412.12 | Shares 92,226
Buy 19 Aug 2025
Value US$1,626,088.13 | Price 444.13 | Shares 76,524
Sale 15 Feb 2025
Value US$1,082.88 | Price 2.56 | Shares 423
Planned sale 4 Apr 2024
Value US$57,666.30 | Price 18.22 | Shares 3,165
Planned sale 4 Apr 2024
Value US$94,926.74 | Price 17.74 | Shares 5,351
Planned sale 4 Apr 2024
Value US$3,800.16 | Price 16.38 | Shares 232
Planned sale 4 Apr 2024
Value US$2,279.97 | Price 15.51 | Shares 147
Planned sale 4 Apr 2024
Value US$640,475.00 | Price 15.07 | Shares 42,500
Proposed sale 4 Apr 2024
Value US$798,787.00 | Price 15.54 | Shares 51,395
Planned sale 6 Mar 2024
Value US$421,937.50 | Price 21.50 | Shares 19,625
Proposed sale 6 Mar 2024
Value US$411,880.00 | Price 20.99 | Shares 19,625
Planned sale 4 Mar 2024
Value US$200,000.00 | Price 20.00 | Shares 10,000
Proposed sale 4 Mar 2024
Value US$199,985.00 | Price 20.00 | Shares 10,000
Planned sale 4 Mar 2024
Value US$615,000.00 | Price 20.50 | Shares 30,000
Proposed sale 4 Mar 2024
Value US$615,000.00 | Price 20.50 | Shares 30,000
Planned sale 4 Mar 2024
Value US$513,501.17 | Price 19.63 | Shares 26,159
Planned sale 4 Mar 2024
Value US$300,000.00 | Price 20.00 | Shares 15,000
Proposed sale 4 Mar 2024
Value US$815,612.00 | Price 19.82 | Shares 41,159
Planned sale 26 Feb 2024
Value US$277,655.28 | Price 17.22 | Shares 16,124
Proposed sale 26 Feb 2024
Value US$275,818.00 | Price 17.11 | Shares 16,124
Proposed sale 7 Feb 2024
Value US$59,998.00 | Price 18.00 | Shares 3,334
Planned sale 7 Feb 2024
Value US$60,012.00 | Price 18.00 | Shares 3,334
Planned sale 5 Feb 2024
Value US$360,937.50 | Price 16.50 | Shares 21,875
Planned sale 5 Feb 2024
Value US$897,204.00 | Price 16.50 | Shares 54,376
Proposed sale 5 Feb 2024
Value US$1,258,054.00 | Price 16.50 | Shares 76,251
Planned sale 1 Feb 2024
Value US$199,740.00 | Price 15.00 | Shares 13,316
Proposed sale 1 Feb 2024
Value US$199,725.00 | Price 15.00 | Shares 13,316
Planned sale 19 Jan 2024
Value US$159,792.00 | Price 12.00 | Shares 13,316
Proposed sale 19 Jan 2024
Value US$159,777.00 | Price 12.00 | Shares 13,316
Planned sale 20 Dec 2023
Value US$190,310.40 | Price 10.08 | Shares 18,880
Proposed sale 20 Dec 2023
Value US$190,295.00 | Price 10.08 | Shares 18,880
Buy 2 Oct 2023
Value US$669,585.00 | Price 4.46 | Shares 150,000
Buy 7 Sep 2023
Value US$1,052,840.00 | Price 5.26 | Shares 200,000
Buy 30 Aug 2023
Value US$73,650.00 | Price 4.91 | Shares 15,000
Planned sale 10 Mar 2023
Value US$32,393.16 | Price 6.03 | Shares 5,372
Buy 14 Feb 2023
Value US$2,532,600.00 | Price 5.07 | Shares 500,000
Buy 19 Jan 2023
Value US$794,925.00 | Price 5.30 | Shares 150,000
Buy 27 Dec 2022
Value US$1,121,800.00 | Price 5.61 | Shares 200,000
Buy 23 Dec 2022
Value US$1,176,800.00 | Price 5.88 | Shares 200,000
Buy 22 Nov 2022
Value US$1,788,180.00 | Price 5.96 | Shares 300,000
Buy 24 Oct 2022
Value US$1,090,500.00 | Price 4.36 | Shares 250,000
Buy 21 Oct 2022
Value US$1,157,100.00 | Price 4.63 | Shares 250,000
Buy 20 Oct 2022
Value US$1,143,564.83 | Price 4.00 | Shares 285,977
Buy 19 Oct 2022
Value US$623,919.30 | Price 3.70 | Shares 168,422
Buy 15 Jun 2022
Value US$98,800.00 | Price 2.47 | Shares 40,000
Buy 19 Nov 2021
Value US$3,700,320.00 | Price 18.50 | Shares 200,000
Planned sale 16 Jul 2021
Value US$125,050.00 | Price 25.01 | Shares 5,000
Buy 16 Jun 2021
Value US$2,104,390.00 | Price 21.04 | Shares 100,000
Buy 15 Jun 2021
Value US$1,539,615.00 | Price 20.53 | Shares 75,000
Planned sale 15 Apr 2021
Value US$154,550.00 | Price 30.91 | Shares 5,000
Planned sale 22 Mar 2021
Value US$495,000.00 | Price 33.00 | Shares 15,000
Planned sale 22 Mar 2021
Value US$125,344.00 | Price 32.00 | Shares 3,917
Planned sale 8 Mar 2021
Value US$576,348.50 | Price 26.50 | Shares 21,749
Planned sale 29 Dec 2020
Value US$12,050.00 | Price 24.10 | Shares 500
Planned sale 30 Nov 2020
Value US$11,675.00 | Price 23.35 | Shares 500
Planned sale 28 Oct 2020
Value US$31,035.00 | Price 20.69 | Shares 1,500
Planned sale 28 Sep 2020
Value US$12,665.00 | Price 25.33 | Shares 500
Planned sale 18 Sep 2020
Value US$586,848.00 | Price 32.00 | Shares 18,339
Planned sale 17 Sep 2020
Value US$1,330,018.56 | Price 29.88 | Shares 44,512
Sale 9 Sep 2020
Value US$187,709.64 | Price 27.11 | Shares 6,924
Sale 9 Sep 2020
Value US$375,446.39 | Price 27.11 | Shares 13,849
Planned sale 26 Aug 2020
Value US$13,549.50 | Price 27.10 | Shares 500
Planned sale 20 Aug 2020
Value US$201,525.00 | Price 26.87 | Shares 7,500
Planned sale 27 Jul 2020
Value US$76,890.00 | Price 25.63 | Shares 3,000
Planned sale 27 Jul 2020
Value US$25,140.00 | Price 25.14 | Shares 1,000
Planned sale 27 Jul 2020
Value US$12,288.57 | Price 25.13 | Shares 489
Planned sale 2 Jul 2020
Value US$93,000.00 | Price 30.00 | Shares 3,100
Planned sale 2 Jul 2020
Value US$6,060.00 | Price 30.00 | Shares 202
Planned sale 24 Jun 2020
Value US$14,245.00 | Price 28.49 | Shares 500
Planned sale 26 May 2020
Value US$13,295.00 | Price 26.59 | Shares 500
Planned sale 20 May 2020
Value US$189,750.00 | Price 25.30 | Shares 7,500
Planned sale 6 May 2020
Value US$88,300.00 | Price 25.00 | Shares 3,532
Planned sale 6 May 2020
Value US$60,000.00 | Price 20.00 | Shares 3,000
Planned sale 6 May 2020
Value US$15,000.00 | Price 15.00 | Shares 1,000
Planned sale 6 May 2020
Value US$5,000.00 | Price 10.00 | Shares 500
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-08-21 2025-08-20 B Purchase
3.7
HEIDEN WILLIAM K
Non-Executive Director
92,226 -49.4%
412.12
US$2,071,369 		92,226 -49.4% 412.12 US$2,071,369
2025-08-21 2025-08-19 B Purchase
3.7
HEIDEN WILLIAM K
Non-Executive Director
76,524 -6.6%
444.13
US$1,626,088 		76,524 -6.6% 444.13 US$1,626,088
2025-02-19 2025-02-15 S Sale
3.3
Smith Beth Ann

VP, Controller & Treasurer

Officer
72,066 +0.7%
347.93
US$596,337 		72,066 +0.7% 347.93 US$596,337
2024-04-08 2024-04-04 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
3,165 -100.0%
18.22
US$57,666 		3,165 -100.0% 18.22 US$57,666
2024-04-08 2024-04-04 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
5,351 -62.8%
17.74
US$94,927 		5,351 -62.8% 17.74 US$94,927
2024-04-08 2024-04-04 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
232 -2.7%
16.38
US$3,800 		232 -2.7% 16.38 US$3,800
2024-04-08 2024-04-04 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
147 -1.7%
15.51
US$2,280 		147 -1.7% 15.51 US$2,280
2024-04-08 2024-04-04 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
42,500 -82.7%
15.07
US$640,475 		42,500 -82.7% 15.07 US$640,475
2024-04-04 2024-04-04 PrS Proposed sale
Peters Jeffrey Stuart

Officer

Officer
51,395
15.54
US$798,787 		51,395 15.54 US$798,787
2024-03-08 2024-03-06 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
19,625 -68.8%
21.50
US$421,938 		19,625 -68.8% 21.50 US$421,938
2024-03-06 2024-03-06 PrS Proposed sale
Peters Jeffrey Stuart

Officer

Officer
19,625
20.99
US$411,880 		19,625 20.99 US$411,880
2024-03-06 2024-03-04 PlS Planned sale
Spitznagel Thomas

Sr VP, Technical Ops

Officer
10,000 -54.6%
20.00
US$200,000 		10,000 -54.6% 20.00 US$200,000
2024-03-06 2024-03-04 PlS Planned sale
3.3
Karrels James

SVP, CFO and Secretary

Officer
30,000 -14.9%
20.50
US$615,000 		30,000 -14.9% 20.50 US$615,000
2024-03-06 2024-03-04 PlS Planned sale
Risser Eric Blasius

Chief Operating Officer

Officer
26,159 -40.2%
19.63
US$513,501 		26,159 -40.2% 19.63 US$513,501
2024-03-06 2024-03-04 PlS Planned sale
Risser Eric Blasius

Chief Operating Officer

Officer
15,000 -18.7%
20.00
US$300,000 		15,000 -18.7% 20.00 US$300,000
2024-03-04 2024-03-04 PrS Proposed sale
Spitznagel Thomas

Officer

Officer
10,000
20.00
US$199,985 		10,000 20.00 US$199,985
2024-03-04 2024-03-04 PrS Proposed sale
Risser Eric Blasius

Officer

Officer
41,159
19.82
US$815,612 		41,159 19.82 US$815,612
2024-03-04 2024-03-04 PrS Proposed sale
3.3
Karrels James

Officer

Officer
30,000
20.50
US$615,000 		30,000 20.50 US$615,000
2024-02-28 2024-02-26 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
16,124 -64.4%
17.22
US$277,655 		16,124 -64.4% 17.22 US$277,655
2024-02-26 2024-02-26 PrS Proposed sale
Peters Jeffrey Stuart

Officer

Officer
16,124
17.11
US$275,818 		16,124 17.11 US$275,818
2024-02-07 2024-02-07 PrS Proposed sale
Bonvini Ezio

Officer

Officer
3,334
18.00
US$59,998 		3,334 18.00 US$59,998
2024-02-07 2024-02-07 PlS Planned sale
Bonvini Ezio

Sr VP, Research & CSO

Officer
3,334 -4.5%
18.00
US$60,012 		3,334 -4.5% 18.00 US$60,012
2024-02-07 2024-02-05 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
21,875 -100.0%
16.50
US$360,938 		21,875 -100.0% 16.50 US$360,938
2024-02-07 2024-02-05 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
54,376 -71.3%
16.50
US$897,204 		54,376 -71.3% 16.50 US$897,204
2024-02-05 2024-02-05 PrS Proposed sale
Peters Jeffrey Stuart

Officer

Officer
76,251
16.50
US$1,258,054 		76,251 16.50 US$1,258,054
2024-02-02 2024-02-01 PlS Planned sale
Bonvini Ezio

Sr VP, Research & CSO

Officer
13,316 -15.1%
15.00
US$199,740 		13,316 -15.1% 15.00 US$199,740
2024-02-01 2024-02-01 PrS Proposed sale
Bonvini Ezio

Officer

Officer
13,316
15.00
US$199,725 		13,316 15.00 US$199,725
2024-01-22 2024-01-19 PlS Planned sale
Bonvini Ezio

Sr VP, Research & CSO

Officer
13,316 -13.1%
12.00
US$159,792 		13,316 -13.1% 12.00 US$159,792
2024-01-19 2024-01-19 PrS Proposed sale
Bonvini Ezio

Officer

Officer
13,316
12.00
US$159,777 		13,316 12.00 US$159,777
2023-12-21 2023-12-20 PlS Planned sale
Bonvini Ezio

Sr VP, Research & CSO

Officer
18,880 -15.7%
10.08
US$190,310 		18,880 -15.7% 10.08 US$190,310
2023-12-20 2023-12-20 PrS Proposed sale
Bonvini Ezio

Officer

Officer
18,880
10.08
US$190,295 		18,880 10.08 US$190,295
2023-10-04 2023-10-02 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
150,000 +1.5%
4.46
US$669,585 		150,000 +1.5% 4.46 US$669,585
2023-09-11 2023-09-07 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
200,000 +2.1%
5.26
US$1,052,840 		200,000 +2.1% 5.26 US$1,052,840
2023-09-01 2023-08-30 B Purchase
2.5
HURWITZ EDWARD
Non-Executive Director
15,000 +83.0%
4.91
US$73,650 		15,000 +83.0% 4.91 US$73,650
2023-03-14 2023-03-10 PlS Planned sale
Peters Jeffrey Stuart

Senior VP and General Counsel

Officer
5,372 -100.0%
6.03
US$32,393 		5,372 -100.0% 6.03 US$32,393
2023-02-16 2023-02-14 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
500,000 +5.5%
5.07
US$2,532,600 		500,000 +5.5% 5.07 US$2,532,600
2023-01-23 2023-01-19 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
150,000 +1.7%
5.30
US$794,925 		150,000 +1.7% 5.30 US$794,925
2022-12-28 2022-12-27 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
200,000 +2.3%
5.61
US$1,121,800 		200,000 +2.3% 5.61 US$1,121,800
2022-12-28 2022-12-23 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
200,000 +2.3%
5.88
US$1,176,800 		200,000 +2.3% 5.88 US$1,176,800
2022-11-25 2022-11-22 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
300,000 +3.6%
5.96
US$1,788,180 		300,000 +3.6% 5.96 US$1,788,180
2022-10-25 2022-10-24 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
250,000 +3.1%
4.36
US$1,090,500 		250,000 +3.1% 4.36 US$1,090,500
2022-10-25 2022-10-21 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
250,000 +3.2%
4.63
US$1,157,100 		250,000 +3.2% 4.63 US$1,157,100
2022-10-21 2022-10-20 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
285,977 +3.8%
4.00
US$1,143,565 		285,977 +3.8% 4.00 US$1,143,565
2022-10-21 2022-10-19 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
168,422 +2.3%
3.70
US$623,919 		168,422 +2.3% 3.70 US$623,919
2022-06-17 2022-06-15 B Purchase
3.3
Karrels James

SVP, CFO and Secretary

Officer
40,000 +26.4%
2.47
US$98,800 		40,000 +26.4% 2.47 US$98,800
2021-11-23 2021-11-19 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
200,000 +2.8%
18.50
US$3,700,320 		200,000 +2.8% 18.50 US$3,700,320
2021-07-20 2021-07-16 PlS Planned sale
Spitznagel Thomas

Sr VP, BPD & Manufacturing

Officer
5,000 -100.0%
25.01
US$125,050 		5,000 -100.0% 25.01 US$125,050
2021-06-17 2021-06-16 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
100,000 +1.6%
21.04
US$2,104,390 		100,000 +1.6% 21.04 US$2,104,390
2021-06-17 2021-06-15 B Purchase
2.4
BIOTECH TARGET N V
Large shareholder
75,000 +1.2%
20.53
US$1,539,615 		75,000 +1.2% 20.53 US$1,539,615
2021-04-19 2021-04-15 PlS Planned sale
Spitznagel Thomas

Sr VP, BPD & Manufacturing

Officer
5,000 -100.0%
30.91
US$154,550 		5,000 -100.0% 30.91 US$154,550
2021-03-24 2021-03-22 PlS Planned sale
3.3
Karrels James

SVP, CFO and Secretary

Officer
15,000 -9.5%
33.00
US$495,000 		15,000 -9.5% 33.00 US$495,000
2021-03-24 2021-03-22 PlS Planned sale
Bonvini Ezio

Sr VP, Research & CSO

Officer
3,917 -4.7%
32.00
US$125,344 		3,917 -4.7% 32.00 US$125,344
2021-03-09 2021-03-08 PlS Planned sale
Peters Jeffrey Stuart

General Counsel

Officer
21,749 -100.0%
26.50
US$576,348 		21,749 -100.0% 26.50 US$576,348
2020-12-30 2020-12-29 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
500 -1.1%
24.10
US$12,050 		500 -1.1% 24.10 US$12,050
2020-12-01 2020-11-30 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
500 -1.1%
23.35
US$11,675 		500 -1.1% 23.35 US$11,675
2020-10-29 2020-10-28 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
1,500 -3.3%
20.69
US$31,035 		1,500 -3.3% 20.69 US$31,035
2020-09-29 2020-09-28 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
500 -1.1%
25.33
US$12,665 		500 -1.1% 25.33 US$12,665
2020-09-21 2020-09-18 PlS Planned sale
Bonvini Ezio

Sr VP, Research & CSO

Officer
18,339 -18.0%
32.00
US$586,848 		18,339 -18.0% 32.00 US$586,848
2020-09-21 2020-09-17 PlS Planned sale
Bonvini Ezio

Sr VP, Research & CSO

Officer
44,512 -30.4%
29.88
US$1,330,019 		44,512 -30.4% 29.88 US$1,330,019
2020-09-10 2020-09-09 S Sale
3.2
Galbraith Kenneth
Non-Executive Director
6,924 -100.0%
27.11
US$187,710 		6,924 -100.0% 27.11 US$187,710
2020-09-10 2020-09-09 S Sale
3.2
Galbraith Kenneth
Non-Executive Director
13,849 -100.0%
27.11
US$375,446 		13,849 -100.0% 27.11 US$375,446
2020-08-27 2020-08-26 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
500 -1.1%
27.10
US$13,550 		500 -1.1% 27.10 US$13,550
2020-08-21 2020-08-20 PlS Planned sale
Spitznagel Thomas

Sr VP, BPD & Manufacturing

Officer
7,500 -100.0%
26.87
US$201,525 		7,500 -100.0% 26.87 US$201,525
2020-07-28 2020-07-27 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
3,000 -6.3%
25.63
US$76,890 		3,000 -6.3% 25.63 US$76,890
2020-07-28 2020-07-27 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
1,000 -2.1%
25.14
US$25,140 		1,000 -2.1% 25.14 US$25,140
2020-07-28 2020-07-27 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
489 -1.1%
25.13
US$12,289 		489 -1.1% 25.13 US$12,289
2020-07-06 2020-07-02 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
3,100 -6.5%
30.00
US$93,000 		3,100 -6.5% 30.00 US$93,000
2020-07-06 2020-07-02 PlS Planned sale
Peters Jeffrey Stuart

General Counsel

Officer
202 -100.0%
30.00
US$6,060 		202 -100.0% 30.00 US$6,060
2020-06-25 2020-06-24 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
500 -1.1%
28.49
US$14,245 		500 -1.1% 28.49 US$14,245
2020-05-27 2020-05-26 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
500 -1.1%
26.59
US$13,295 		500 -1.1% 26.59 US$13,295
2020-05-21 2020-05-20 PlS Planned sale
Spitznagel Thomas

Sr VP, BPD & Manufacturing

Officer
7,500 -100.0%
25.30
US$189,750 		7,500 -100.0% 25.30 US$189,750
2020-05-07 2020-05-06 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
3,532 -7.4%
25.00
US$88,300 		3,532 -7.4% 25.00 US$88,300
2020-05-07 2020-05-06 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
3,000 -5.9%
20.00
US$60,000 		3,000 -5.9% 20.00 US$60,000
2020-05-07 2020-05-06 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
1,000 -1.9%
15.00
US$15,000 		1,000 -1.9% 15.00 US$15,000
2020-05-07 2020-05-06 PlS Planned sale
Risser Eric Blasius

Sr VP & Chief Business Officer

Officer
500 -1.0%
10.00
US$5,000 		500 -1.0% 10.00 US$5,000
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