Lyell Immunopharma Inc (LYEL)

The most recent insider trading activity occurred on March 6, 2026, with significant buy transactions totaling over $24.9 million from ARCH Venture Partners IX, LLC and ARCH Venture Fund XIII, L.P. Prior to this, several executives made smaller sell transactions in February and November 2025.
Stock chart
Ticker: LYEL Exchange: NSM


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Purchase Sale Planned purchase Planned sale Net purchase Net sale Activity signal Earnings
Top insiders
Trades
ARCH Venture Partners IX, LLC
1 purchase — total 12,499,985 USD
Buy 6 Mar 2026
Value US$2,481,598.43 | Price 167.35 | Shares 28,439
Buy 6 Mar 2026
Value US$4,156,170.18 | Price 253.67 | Shares 5,880
Sale 11 Feb 2026
Value US$28,910.04 | Price 23.39 | Shares 1,236
Sale 11 Feb 2026
Value US$174,372.45 | Price 23.39 | Shares 7,455
Sale 11 Feb 2026
Value US$39,084.69 | Price 23.39 | Shares 1,671
Sale 10 Feb 2026
Value US$3,398.64 | Price 23.12 | Shares 147
Sale 10 Feb 2026
Value US$10,126.56 | Price 23.12 | Shares 438
Sale 10 Feb 2026
Value US$2,520.08 | Price 23.12 | Shares 109
Sale 10 Feb 2026
Value US$5,872.48 | Price 23.12 | Shares 254
Sale 30 Dec 2025
Value US$30,251.52 | Price 32.32 | Shares 936
Sale 24 Dec 2025
Value US$43,929.12 | Price 38.67 | Shares 1,136
Sale 10 Nov 2025
Value US$1,531.40 | Price 16.12 | Shares 95
Sale 10 Nov 2025
Value US$3,847.90 | Price 16.10 | Shares 239
Sale 10 Nov 2025
Value US$6,637.32 | Price 16.11 | Shares 412
Sale 10 Nov 2025
Value US$2,230.08 | Price 16.16 | Shares 138
Sale 21 Aug 2025
Value US$76,517.81 | Price 10.54 | Shares 7,257
Sale 21 Aug 2025
Value US$15,320.43 | Price 10.54 | Shares 1,453
Sale 21 Aug 2025
Value US$10,586.18 | Price 10.54 | Shares 1,004
Sale 21 Aug 2025
Value US$15,320.43 | Price 10.54 | Shares 1,453
Sale 12 Aug 2025
Value US$4,197.23 | Price 10.34 | Shares 406
Sale 12 Aug 2025
Value US$971.77 | Price 10.34 | Shares 94
Sale 12 Aug 2025
Value US$1,405.97 | Price 10.34 | Shares 136
Sale 12 Aug 2025
Value US$1,405.97 | Price 10.34 | Shares 136
Sale 11 Aug 2025
Value US$4,115.67 | Price 10.53 | Shares 391
Planned sale 11 Aug 2025
Value US$957.87 | Price 10.53 | Shares 91
Planned sale 11 Aug 2025
Value US$1,378.91 | Price 10.53 | Shares 131
Planned sale 11 Aug 2025
Value US$1,378.91 | Price 10.53 | Shares 131
Buy 31 Mar 2025
Value US$19,958.40 | Price 0.56 | Shares 35,640
Buy 21 Mar 2025
Value US$115,220.00 | Price 0.58 | Shares 200,000
Buy 17 Mar 2025
Value US$111,620.00 | Price 0.56 | Shares 200,000
Buy 14 Mar 2025
Value US$94,942.20 | Price 0.60 | Shares 158,000
Buy 14 Mar 2025
Value US$106,190.00 | Price 0.61 | Shares 175,000
Sale 15 Aug 2023
Value US$132,285.60 | Price 2.28 | Shares 58,020
Proposed sale 15 Aug 2023
Value US$10,271.00 | Price 2.29 | Shares 4,485
Proposed sale 15 Aug 2023
Value US$10,271.00 | Price 2.29 | Shares 4,485
Proposed sale 15 Aug 2023
Value US$102,054.00 | Price 2.29 | Shares 44,565
Proposed sale 15 Aug 2023
Value US$10,271.00 | Price 2.29 | Shares 4,485
Proposed sale 13 Jul 2023
Value US$42,050.00 | Price 2.90 | Shares 14,500
Proposed sale 13 Jul 2023
Value US$9,570.00 | Price 2.90 | Shares 3,300
Proposed sale 13 Jul 2023
Value US$9,570.00 | Price 2.90 | Shares 3,300
Proposed sale 13 Jul 2023
Value US$9,570.00 | Price 2.90 | Shares 3,300
Sale 23 Sep 2022
Value US$71,041.11 | Price 6.40 | Shares 11,100
Buy 21 Jun 2021
Value US$300,016.00 | Price 17.00 | Shares 17,648
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Value Details
2026-03-09 2026-03-06 B Purchase Large shareholder
28,439 +24.3%
167.35
US$2,481,598
28,439 +24.3% 167.35 US$2,481,598
2026-03-09 2026-03-06 B Purchase Large shareholder
5,880 +37.0%
253.67
US$4,156,170
5,880 +37.0% 253.67 US$4,156,170
2026-02-12 2026-02-11 S Sale

Chief Operating Officer

Officer
5,416 -25.5%
104.51
US$3,993,087
5,416 -25.5% 104.51 US$3,993,087
2026-02-12 2026-02-11 S Sale

President and CEO

Executive Director
7,455 -9.1%
23.39
US$174,372
7,455 -9.1% 23.39 US$174,372
2026-02-12 2026-02-11 S Sale

Chief Scientific Officer

Officer
1,671 -9.0%
23.39
US$39,085
1,671 -9.0% 23.39 US$39,085
2026-02-11 2026-02-10 S Sale

Chief Scientific Officer

Officer
147 -0.8%
23.12
US$3,399
147 -0.8% 23.12 US$3,399
2026-02-11 2026-02-10 S Sale

President and CEO

Executive Director
438 -0.5%
23.12
US$10,127
438 -0.5% 23.12 US$10,127
2026-02-11 2026-02-10 S Sale

Chief Operating Officer

Officer
109 -0.6%
23.12
US$2,520
109 -0.6% 23.12 US$2,520
2026-02-11 2026-02-10 S Sale

VP, Corporate Controller

Officer
254 -1.6%
23.12
US$5,872
254 -1.6% 23.12 US$5,872
2026-01-06 2025-12-30 S Sale

VP, Corporate Controller

Officer
936 -11.6%
32.32
US$30,252
936 -11.6% 32.32 US$30,252
2026-01-06 2025-12-24 S Sale

VP, Corporate Controller

Officer
1,136 -12.3%
38.67
US$43,929
1,136 -12.3% 38.67 US$43,929
2025-11-12 2025-11-10 S Sale

Chief Operating Officer

Officer
95 -0.6%
16.12
US$1,531
95 -0.6% 16.12 US$1,531
2025-11-12 2025-11-10 S Sale

VP, Corporate Controller

Officer
239 -2.5%
16.10
US$3,848
239 -2.5% 16.10 US$3,848
2025-11-12 2025-11-10 S Sale

President and CEO

Executive Director
412 -0.6%
16.11
US$6,637
412 -0.6% 16.11 US$6,637
2025-11-12 2025-11-10 S Sale

Chief Scientific Officer

Officer
138 -0.9%
16.16
US$2,230
138 -0.9% 16.16 US$2,230
2025-08-22 2025-08-21 S Sale

President and CEO

Executive Director
7,257 -9.7%
10.54
US$76,518
7,257 -9.7% 10.54 US$76,518
2025-08-22 2025-08-21 S Sale

Chief Scientific Officer

Officer
1,453 -8.6%
10.54
US$15,320
1,453 -8.6% 10.54 US$15,320
2025-08-22 2025-08-21 S Sale

Chief Operating Officer

Officer
1,004 -6.0%
10.54
US$10,586
1,004 -6.0% 10.54 US$10,586
2025-08-22 2025-08-21 S Sale

Chief Financial Officer

Officer
1,453 -8.7%
10.54
US$15,320
1,453 -8.7% 10.54 US$15,320
2025-08-13 2025-08-12 S Sale

President and CEO

Executive Director
406 -1.2%
10.34
US$4,197
406 -1.2% 10.34 US$4,197
2025-08-13 2025-08-12 S Sale

Chief Operating Officer

Officer
94 -1.1%
10.34
US$972
94 -1.1% 10.34 US$972
2025-08-13 2025-08-12 S Sale

Chief Scientific Officer

Officer
136 -1.5%
10.34
US$1,406
136 -1.5% 10.34 US$1,406
2025-08-13 2025-08-12 S Sale

Chief Financial Officer

Officer
136 -1.5%
10.34
US$1,406
136 -1.5% 10.34 US$1,406
2025-08-13 2025-08-11 S Sale

President and CEO

Executive Director
391 -1.1%
10.53
US$4,116
391 -1.1% 10.53 US$4,116
2025-08-13 2025-08-11 PlS Planned sale

Chief Operating Officer

Officer
91 -1.0%
10.53
US$958
91 -1.0% 10.53 US$958
2025-08-13 2025-08-11 PlS Planned sale

Chief Scientific Officer

Officer
131 -1.4%
10.53
US$1,379
131 -1.4% 10.53 US$1,379
2025-08-13 2025-08-11 PlS Planned sale

Chief Financial Officer

Officer
131 -1.5%
10.53
US$1,379
131 -1.5% 10.53 US$1,379
2025-04-02 2025-03-31 B Purchase Non-Executive Director
35,640 +inf%
0.56
US$19,958
35,640 +inf% 0.56 US$19,958
2025-03-25 2025-03-21 B Purchase Non-Executive Director
200,000 +inf%
0.58
US$115,220
200,000 +inf% 0.58 US$115,220
2025-03-18 2025-03-17 B Purchase

Chief Financial Officer

Officer
200,000 +inf%
0.56
US$111,620
200,000 +inf% 0.56 US$111,620
2025-03-18 2025-03-14 B Purchase Non-Executive Director
158,000 +23.1%
0.60
US$94,942
158,000 +23.1% 0.60 US$94,942
2025-03-18 2025-03-14 B Purchase

President and CEO

Executive Director
175,000 +32.6%
0.61
US$106,190
175,000 +32.6% 0.61 US$106,190
2023-08-17 2023-08-15 S Sale Non-Executive Director
58,020 -5.9%
2.28
US$132,286
58,020 -5.9% 2.28 US$132,286
2023-08-15 2023-08-15 PrS Proposed sale

Director

Non-Executive Director
4,485
2.29
US$10,271
4,485 2.29 US$10,271
2023-08-15 2023-08-15 PrS Proposed sale

Director

Non-Executive Director
4,485
2.29
US$10,271
4,485 2.29 US$10,271
2023-08-15 2023-08-15 PrS Proposed sale

Director

Non-Executive Director
44,565
2.29
US$102,054
44,565 2.29 US$102,054
2023-08-15 2023-08-15 PrS Proposed sale

Director

Non-Executive Director
4,485
2.29
US$10,271
4,485 2.29 US$10,271
2023-07-17 2023-07-13 PrS Proposed sale

Officer; Director

Executive Director
14,500
2.90
US$42,050
14,500 2.90 US$42,050
2023-07-17 2023-07-13 PrS Proposed sale

Officer; Director

Executive Director
3,300
2.90
US$9,570
3,300 2.90 US$9,570
2023-07-17 2023-07-13 PrS Proposed sale

Officer; Director

Executive Director
3,300
2.90
US$9,570
3,300 2.90 US$9,570
2023-07-17 2023-07-13 PrS Proposed sale

Officer; Director

Executive Director
3,300
2.90
US$9,570
3,300 2.90 US$9,570
2022-09-27 2022-09-23 S Sale Non-Executive Director
11,100 -1.1%
6.40
US$71,041
11,100 -1.1% 6.40 US$71,041
2021-06-23 2021-06-21 B Purchase Non-Executive Director
17,648 +inf%
17.00
US$300,016
17,648 +inf% 17.00 US$300,016