United States Biotechnology & Medical Research

Lyell Immunopharma Inc (LYEL)

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Lyell Immunopharma Inc. experienced nine insider trading transactions over the past ninety days, all involving sales totaling approximately $214,668. Six executives offloaded shares during this period, coinciding with a 15.5% decline in stock value. These divestments occurred following the August 2026 earnings report, where the firm slightly exceeded expectations.
Ticker: LYEL Exchange: NSM
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Insider trades have triggered activity signals for Lyell Immunopharma Inc. Upgrade to see score, net flow, insiders and the full signal context.

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Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Aguirre Jarrad Mattieu Chief Medical Officer Officer
Transaction date
Sale
Price
340.78
Quantity 49,822 +12.8%
Value US$696,028
3.2
Shook David Chief Medical Officer Officer
Transaction date
Sale
Price
270.41
Quantity 83,194 +0.9%
Value US$1,400,880
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Sale
Price
301.47
Quantity 32,606 +3.1%
Value US$2,323,543
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
15.54
Quantity 9,589 -13.0%
Value US$149,013
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Sale
Price
15.54
Quantity 1,457 -8.2%
Value US$22,642
3.9
Bulis Veronica Sanchez VP, Corporate Controller Officer
Transaction date
Sale
Price
14.34
Quantity 621 -4.0%
Value US$8,905
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Sale
Price
14.34
Quantity 131 -0.7%
Value US$1,879
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Sale
Price
14.34
Quantity 89 -0.5%
Value US$1,276
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
14.34
Quantity 390 -0.5%
Value US$5,593
3.2
Shook David Chief Medical Officer Officer
Transaction date
Planned sale
Price
12.64
Quantity 1,977 -8.6%
Value US$24,989
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
18.91
Quantity 388 -0.5%
Value US$7,337
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Planned sale
Price
18.92
Quantity 130 -0.7%
Value US$2,460
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Planned sale
Price
18.92
Quantity 89 -0.5%
Value US$1,684
3.9
Bulis Veronica Sanchez VP, Corporate Controller Officer
Transaction date
Sale
Price
18.91
Quantity 217 -1.4%
Value US$4,103
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Sale
Price
23.39
Quantity 1,236 -6.5%
Value US$28,910
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
23.39
Quantity 7,455 -9.1%
Value US$174,372
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Sale
Price
23.39
Quantity 1,671 -9.0%
Value US$39,085
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Sale
Price
23.12
Quantity 147 -0.8%
Value US$3,399
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
23.12
Quantity 438 -0.5%
Value US$10,127
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Sale
Price
23.12
Quantity 109 -0.6%
Value US$2,520
3.9
Bulis Veronica Sanchez VP, Corporate Controller Officer
Transaction date
Sale
Price
23.12
Quantity 254 -1.6%
Value US$5,872
3.9
Bulis Veronica Sanchez VP, Corporate Controller Officer
Transaction date
Sale
Price
32.32
Quantity 936 -11.6%
Value US$30,252
3.9
Bulis Veronica Sanchez VP, Corporate Controller Officer
Transaction date
Sale
Price
38.67
Quantity 1,136 -12.3%
Value US$43,929
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Sale
Price
16.12
Quantity 95 -0.6%
Value US$1,531
3.9
Bulis Veronica Sanchez VP, Corporate Controller Officer
Transaction date
Sale
Price
16.10
Quantity 239 -2.5%
Value US$3,848
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
16.11
Quantity 412 -0.6%
Value US$6,637
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Sale
Price
16.16
Quantity 138 -0.9%
Value US$2,230
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
10.54
Quantity 7,257 -9.7%
Value US$76,518
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Sale
Price
10.54
Quantity 1,453 -8.6%
Value US$15,320
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Sale
Price
10.54
Quantity 1,004 -6.0%
Value US$10,586
1.5
Newton Charles W. Chief Financial Officer Officer
Transaction date
Sale
Price
10.54
Quantity 1,453 -8.7%
Value US$15,320
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
10.34
Quantity 406 -1.2%
Value US$4,197
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Sale
Price
10.34
Quantity 94 -1.1%
Value US$972
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Sale
Price
10.34
Quantity 136 -1.5%
Value US$1,406
1.5
Newton Charles W. Chief Financial Officer Officer
Transaction date
Sale
Price
10.34
Quantity 136 -1.5%
Value US$1,406
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Sale
Price
10.53
Quantity 391 -1.1%
Value US$4,116
2.8
Hill Stephen J. Chief Operating Officer Officer
Transaction date
Planned sale
Price
10.53
Quantity 91 -1.0%
Value US$958
2.8
Lee Gary K. Chief Scientific Officer Officer
Transaction date
Planned sale
Price
10.53
Quantity 131 -1.4%
Value US$1,379
1.5
Newton Charles W. Chief Financial Officer Officer
Transaction date
Planned sale
Price
10.53
Quantity 131 -1.5%
Value US$1,379
1.4
BRAWLEY OTIS W Non-Executive Director
Transaction date
Purchase
Price
0.56
Quantity 35,640 +inf%
Value US$19,958
0.6
Ramachandra Sumant Non-Executive Director
Transaction date
Purchase
Price
0.58
Quantity 200,000 +inf%
Value US$115,220
1.5
Newton Charles W. Chief Financial Officer Officer
Transaction date
Purchase
Price
0.56
Quantity 200,000 +inf%
Value US$111,620
3.2
Klausner Richard Non-Executive Director
Transaction date
Purchase
Price
0.60
Quantity 158,000 +23.1%
Value US$94,942
2.4
Seely Lynn President and CEO Executive Director
Transaction date
Purchase
Price
0.61
Quantity 175,000 +32.6%
Value US$106,190
3.2
Klausner Richard Non-Executive Director
Transaction date
Sale
Price
2.28
Quantity 58,020 -5.9%
Value US$132,286
3.2
Klausner Richard Director Non-Executive Director
Transaction date
Proposed sale
Price
2.29
Quantity 4,485
Value US$10,271
3.2
Klausner Richard Director Non-Executive Director
Transaction date
Proposed sale
Price
2.29
Quantity 4,485
Value US$10,271
3.2
Klausner Richard Director Non-Executive Director
Transaction date
Proposed sale
Price
2.29
Quantity 44,565
Value US$102,054
3.2
Klausner Richard Director Non-Executive Director
Transaction date
Proposed sale
Price
2.29
Quantity 4,485
Value US$10,271
3.2
Klausner Richard Officer; Director Executive Director
Transaction date
Proposed sale
Price
2.90
Quantity 14,500
Value US$42,050
3.2
Klausner Richard Officer; Director Executive Director
Transaction date
Proposed sale
Price
2.90
Quantity 3,300
Value US$9,570
3.2
Klausner Richard Officer; Director Executive Director
Transaction date
Proposed sale
Price
2.90
Quantity 3,300
Value US$9,570
3.2
Klausner Richard Officer; Director Executive Director
Transaction date
Proposed sale
Price
2.90
Quantity 3,300
Value US$9,570
3.2
Klausner Richard Non-Executive Director
Transaction date
Sale
Price
6.40
Quantity 11,100 -1.1%
Value US$71,041
0.6
FRIEDMAN CATHY Non-Executive Director
Transaction date
Purchase
Price
17.00
Quantity 17,648 +inf%
Value US$300,016
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-10-13 2026-10-12 S Sale
Aguirre Jarrad Mattieu

Chief Medical Officer

Officer
49,822 +12.8%
340.78
US$696,028 		49,822 +12.8% 340.78 US$696,028
2026-09-10 2026-09-10 S Sale
3.2
Shook David

Chief Medical Officer

Officer
83,194 +0.9%
270.41
US$1,400,880 		83,194 +0.9% 270.41 US$1,400,880
2026-08-25 2026-08-21 S Sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
32,606 +3.1%
301.47
US$2,323,543 		32,606 +3.1% 301.47 US$2,323,543
2026-08-25 2026-08-21 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
9,589 -13.0%
15.54
US$149,013 		9,589 -13.0% 15.54 US$149,013
2026-08-25 2026-08-21 S Sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
1,457 -8.2%
15.54
US$22,642 		1,457 -8.2% 15.54 US$22,642
2026-08-11 2026-08-10 S Sale
3.9
Bulis Veronica Sanchez

VP, Corporate Controller

Officer
621 -4.0%
14.34
US$8,905 		621 -4.0% 14.34 US$8,905
2026-08-11 2026-08-10 S Sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
131 -0.7%
14.34
US$1,879 		131 -0.7% 14.34 US$1,879
2026-08-11 2026-08-10 S Sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
89 -0.5%
14.34
US$1,276 		89 -0.5% 14.34 US$1,276
2026-08-11 2026-08-10 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
390 -0.5%
14.34
US$5,593 		390 -0.5% 14.34 US$5,593
2026-07-20 2026-07-17 S Sale
Innovative Cellular Therapeutics Holdings Ltd
Large shareholder
10 -0.0%
13.70
US$137 		10 -0.0% 13.70 US$137
2026-07-17 2026-07-16 S Sale
Innovative Cellular Therapeutics Holdings Ltd
Large shareholder
10 -0.0%
13.73
US$137 		10 -0.0% 13.73 US$137
2026-06-11 2026-06-10 PlS Planned sale
3.2
Shook David

Chief Medical Officer

Officer
1,977 -8.6%
12.64
US$24,989 		1,977 -8.6% 12.64 US$24,989
2026-06-15 2026-05-11 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
388 -0.5%
18.91
US$7,337 		388 -0.5% 18.91 US$7,337
2026-06-15 2026-05-11 PlS Planned sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
130 -0.7%
18.92
US$2,460 		130 -0.7% 18.92 US$2,460
2026-06-15 2026-05-11 PlS Planned sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
89 -0.5%
18.92
US$1,684 		89 -0.5% 18.92 US$1,684
2026-06-15 2026-05-11 S Sale
3.9
Bulis Veronica Sanchez

VP, Corporate Controller

Officer
217 -1.4%
18.91
US$4,103 		217 -1.4% 18.91 US$4,103
2026-03-09 2026-03-06 B Purchase
ARCH Venture Partners IX, LLC
Large shareholder
488,090 +52.0%
25.61
US$12,499,985 		488,090 +52.0% 25.61 US$12,499,985
2026-03-09 2026-03-06 B Purchase
ARCH Venture Fund XIII, L.P.
Large shareholder
488,090 +52.0%
25.61
US$12,499,985 		488,090 +52.0% 25.61 US$12,499,985
2026-02-12 2026-02-11 S Sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
1,236 -6.5%
23.39
US$28,910 		1,236 -6.5% 23.39 US$28,910
2026-02-12 2026-02-11 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
7,455 -9.1%
23.39
US$174,372 		7,455 -9.1% 23.39 US$174,372
2026-02-12 2026-02-11 S Sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
1,671 -9.0%
23.39
US$39,085 		1,671 -9.0% 23.39 US$39,085
2026-02-11 2026-02-10 S Sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
147 -0.8%
23.12
US$3,399 		147 -0.8% 23.12 US$3,399
2026-02-11 2026-02-10 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
438 -0.5%
23.12
US$10,127 		438 -0.5% 23.12 US$10,127
2026-02-11 2026-02-10 S Sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
109 -0.6%
23.12
US$2,520 		109 -0.6% 23.12 US$2,520
2026-02-11 2026-02-10 S Sale
3.9
Bulis Veronica Sanchez

VP, Corporate Controller

Officer
254 -1.6%
23.12
US$5,872 		254 -1.6% 23.12 US$5,872
2026-01-06 2025-12-30 S Sale
3.9
Bulis Veronica Sanchez

VP, Corporate Controller

Officer
936 -11.6%
32.32
US$30,252 		936 -11.6% 32.32 US$30,252
2026-01-06 2025-12-24 S Sale
3.9
Bulis Veronica Sanchez

VP, Corporate Controller

Officer
1,136 -12.3%
38.67
US$43,929 		1,136 -12.3% 38.67 US$43,929
2025-11-12 2025-11-10 S Sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
95 -0.6%
16.12
US$1,531 		95 -0.6% 16.12 US$1,531
2025-11-12 2025-11-10 S Sale
3.9
Bulis Veronica Sanchez

VP, Corporate Controller

Officer
239 -2.5%
16.10
US$3,848 		239 -2.5% 16.10 US$3,848
2025-11-12 2025-11-10 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
412 -0.6%
16.11
US$6,637 		412 -0.6% 16.11 US$6,637
2025-11-12 2025-11-10 S Sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
138 -0.9%
16.16
US$2,230 		138 -0.9% 16.16 US$2,230
2025-08-22 2025-08-21 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
7,257 -9.7%
10.54
US$76,518 		7,257 -9.7% 10.54 US$76,518
2025-08-22 2025-08-21 S Sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
1,453 -8.6%
10.54
US$15,320 		1,453 -8.6% 10.54 US$15,320
2025-08-22 2025-08-21 S Sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
1,004 -6.0%
10.54
US$10,586 		1,004 -6.0% 10.54 US$10,586
2025-08-22 2025-08-21 S Sale
1.5
Newton Charles W.

Chief Financial Officer

Officer
1,453 -8.7%
10.54
US$15,320 		1,453 -8.7% 10.54 US$15,320
2025-08-13 2025-08-12 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
406 -1.2%
10.34
US$4,197 		406 -1.2% 10.34 US$4,197
2025-08-13 2025-08-12 S Sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
94 -1.1%
10.34
US$972 		94 -1.1% 10.34 US$972
2025-08-13 2025-08-12 S Sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
136 -1.5%
10.34
US$1,406 		136 -1.5% 10.34 US$1,406
2025-08-13 2025-08-12 S Sale
1.5
Newton Charles W.

Chief Financial Officer

Officer
136 -1.5%
10.34
US$1,406 		136 -1.5% 10.34 US$1,406
2025-08-13 2025-08-11 S Sale
2.4
Seely Lynn

President and CEO

Executive Director
391 -1.1%
10.53
US$4,116 		391 -1.1% 10.53 US$4,116
2025-08-13 2025-08-11 PlS Planned sale
2.8
Hill Stephen J.

Chief Operating Officer

Officer
91 -1.0%
10.53
US$958 		91 -1.0% 10.53 US$958
2025-08-13 2025-08-11 PlS Planned sale
2.8
Lee Gary K.

Chief Scientific Officer

Officer
131 -1.4%
10.53
US$1,379 		131 -1.4% 10.53 US$1,379
2025-08-13 2025-08-11 PlS Planned sale
1.5
Newton Charles W.

Chief Financial Officer

Officer
131 -1.5%
10.53
US$1,379 		131 -1.5% 10.53 US$1,379
2025-04-02 2025-03-31 B Purchase
1.4
BRAWLEY OTIS W
Non-Executive Director
35,640 +inf%
0.56
US$19,958 		35,640 +inf% 0.56 US$19,958
2025-03-25 2025-03-21 B Purchase
0.6
Ramachandra Sumant
Non-Executive Director
200,000 +inf%
0.58
US$115,220 		200,000 +inf% 0.58 US$115,220
2025-03-18 2025-03-17 B Purchase
1.5
Newton Charles W.

Chief Financial Officer

Officer
200,000 +inf%
0.56
US$111,620 		200,000 +inf% 0.56 US$111,620
2025-03-18 2025-03-14 B Purchase
3.2
Klausner Richard
Non-Executive Director
158,000 +23.1%
0.60
US$94,942 		158,000 +23.1% 0.60 US$94,942
2025-03-18 2025-03-14 B Purchase
2.4
Seely Lynn

President and CEO

Executive Director
175,000 +32.6%
0.61
US$106,190 		175,000 +32.6% 0.61 US$106,190
2023-08-17 2023-08-15 S Sale
3.2
Klausner Richard
Non-Executive Director
58,020 -5.9%
2.28
US$132,286 		58,020 -5.9% 2.28 US$132,286
2023-08-15 2023-08-15 PrS Proposed sale
3.2
Klausner Richard

Director

Non-Executive Director
4,485
2.29
US$10,271 		4,485 2.29 US$10,271
2023-08-15 2023-08-15 PrS Proposed sale
3.2
Klausner Richard

Director

Non-Executive Director
4,485
2.29
US$10,271 		4,485 2.29 US$10,271
2023-08-15 2023-08-15 PrS Proposed sale
3.2
Klausner Richard

Director

Non-Executive Director
44,565
2.29
US$102,054 		44,565 2.29 US$102,054
2023-08-15 2023-08-15 PrS Proposed sale
3.2
Klausner Richard

Director

Non-Executive Director
4,485
2.29
US$10,271 		4,485 2.29 US$10,271
2023-07-17 2023-07-13 PrS Proposed sale
3.2
Klausner Richard

Officer; Director

Executive Director
14,500
2.90
US$42,050 		14,500 2.90 US$42,050
2023-07-17 2023-07-13 PrS Proposed sale
3.2
Klausner Richard

Officer; Director

Executive Director
3,300
2.90
US$9,570 		3,300 2.90 US$9,570
2023-07-17 2023-07-13 PrS Proposed sale
3.2
Klausner Richard

Officer; Director

Executive Director
3,300
2.90
US$9,570 		3,300 2.90 US$9,570
2023-07-17 2023-07-13 PrS Proposed sale
3.2
Klausner Richard

Officer; Director

Executive Director
3,300
2.90
US$9,570 		3,300 2.90 US$9,570
2022-09-27 2022-09-23 S Sale
3.2
Klausner Richard
Non-Executive Director
11,100 -1.1%
6.40
US$71,041 		11,100 -1.1% 6.40 US$71,041
2021-06-23 2021-06-21 B Purchase
0.6
FRIEDMAN CATHY
Non-Executive Director
17,648 +inf%
17.00
US$300,016 		17,648 +inf% 17.00 US$300,016
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