United States Biotechnology & Medical Research

Iteos Therapeutics Inc (ITOS)

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Ticker: ITOS Exchange: NMS
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• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
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Planned sale 10 Jun 2025
Value US$168,710.01 | Price 64.70 | Shares 82,955 (-47.3%)
Planned sale 10 Jun 2025
Value US$3,414,343.61 | Price 390.03 | Shares 12,727 (+42.0%)
Proposed sale 10 Jun 2025
Value US$523,875.66 | Price 10.02 | Shares 52,283
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2025-06-11 2025-06-10 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
82,955 -47.3%
64.70
US$168,710 		82,955 -47.3% 64.70 US$168,710
2025-06-11 2025-06-10 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
12,727 +42.0%
390.03
US$3,414,344 		12,727 +42.0% 390.03 US$3,414,344
2025-06-10 2025-06-10 PrS Proposed sale
3.2
Detheux Michel

Officer

Officer
48,185
229.66
US$1,540,276 		48,185 229.66 US$1,540,276
2025-06-11 2025-06-09 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
43,882 -100.0%
10.03
US$440,136 		43,882 -100.0% 10.03 US$440,136
2025-06-11 2025-06-09 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
8,400 -5.8%
10.03
US$84,252 		8,400 -5.8% 10.03 US$84,252
2025-06-09 2025-06-09 PrS Proposed sale
3.2
Detheux Michel

Officer

Officer
52,282
10.17
US$531,708 		52,282 10.17 US$531,708
2025-06-06 2025-06-06 PrS Proposed sale
3.2
Detheux Michel

Officer

Officer
52,282
10.19
US$532,754 		52,282 10.19 US$532,754
2025-06-06 2025-06-06 PrS Proposed sale
3.0
DAVID L HALLAL

Director

Non-Executive Director
38,228
10.24
US$391,489 		38,228 10.24 US$391,489
2025-06-06 2025-06-06 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
43,882 -100.0%
10.21
US$448,035 		43,882 -100.0% 10.21 US$448,035
2025-06-06 2025-06-06 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
8,400 -5.8%
10.21
US$85,764 		8,400 -5.8% 10.21 US$85,764
2025-06-06 2025-06-06 PlS Planned sale
3.0
Hallal David
Non-Executive Director
38,228 -100.0%
10.24
US$391,455 		38,228 -100.0% 10.24 US$391,455
2025-06-06 2025-06-05 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
43,882 -100.0%
10.15
US$445,402 		43,882 -100.0% 10.15 US$445,402
2025-06-06 2025-06-05 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
8,400 -5.8%
10.15
US$85,260 		8,400 -5.8% 10.15 US$85,260
2025-06-06 2025-06-05 PlS Planned sale
3.0
Hallal David
Non-Executive Director
38,227 -100.0%
10.15
US$388,004 		38,227 -100.0% 10.15 US$388,004
2025-06-05 2025-06-05 PrS Proposed sale
3.2
Detheux Michel

Officer

Officer
52,282
10.22
US$534,322 		52,282 10.22 US$534,322
2025-06-05 2025-06-05 PrS Proposed sale
3.0
DAVID L HALLAL

Director

Non-Executive Director
38,227
10.15
US$388,103 		38,227 10.15 US$388,103
2025-06-06 2025-06-04 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
43,883 -100.0%
10.10
US$443,218 		43,883 -100.0% 10.10 US$443,218
2025-06-06 2025-06-04 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
8,400 -5.8%
10.10
US$84,840 		8,400 -5.8% 10.10 US$84,840
2025-06-06 2025-06-04 PlS Planned sale
3.0
Hallal David
Non-Executive Director
38,227 -100.0%
10.07
US$384,946 		38,227 -100.0% 10.07 US$384,946
2025-06-04 2025-06-04 PrS Proposed sale
3.2
Detheux Michel

Officer; President and CEO

Officer
52,283
10.06
US$525,967 		52,283 10.06 US$525,967
2025-06-04 2025-06-04 PrS Proposed sale
3.0
DAVID L HALLAL

Director

Non-Executive Director
38,227
10.07
US$384,782 		38,227 10.07 US$384,782
2025-05-16 2025-05-15 B Purchase
3.1
EcoR1 Capital, LLC
Large shareholder
3,300,000 +44.7%
8.00
US$26,400,000 		3,300,000 +44.7% 8.00 US$26,400,000
2025-05-16 2025-05-14 B Purchase
3.1
EcoR1 Capital, LLC
Large shareholder
1,658,978 +29.0%
7.41
US$12,285,562 		1,658,978 +29.0% 7.41 US$12,285,562
2025-05-15 2025-05-13 S Sale
3.2
MPM BioVentures 2014, L.P.
630,191 -23.0%
8.06
US$5,079,339 		630,191 -23.0% 8.06 US$5,079,339
2025-05-15 2025-05-13 S Sale
3.3
MPM BIOVENTURES 2018, L.P.
630,191 -23.0%
8.06
US$5,079,339 		630,191 -23.0% 8.06 US$5,079,339
2025-05-15 2025-05-13 S Sale
3.1
GADICKE ANSBERT
1,031,931 -23.0%
8.06
US$8,317,364 		1,031,931 -23.0% 8.06 US$8,317,364
2024-11-19 2024-11-19 B Purchase
2.9
Gall Matthew

Chief Financial Officer

Officer
5,000 +8.3%
7.73
US$38,635 		5,000 +8.3% 7.73 US$38,635
2023-10-12 2023-10-12 B Purchase
2.9
Gall Matthew

Chief Financial Officer

Officer
5,000 +34.7%
8.37
US$41,850 		5,000 +34.7% 8.37 US$41,850
2023-08-25 2023-08-23 S Sale
3.6
Boxer Capital, LLC

See remarks
219,638 -10.9%
16.87
US$3,705,293 		219,638 -10.9% 16.87 US$3,705,293
2023-08-25 2023-08-23 S Sale
3.6
Boxer Capital, LLC

See remarks
95,516 -4.5%
15.63
US$1,492,915 		95,516 -4.5% 15.63 US$1,492,915
2023-08-25 2023-08-23 S Sale
3.6
Boxer Capital, LLC

See remarks
34,846 -1.6%
14.19
US$494,465 		34,846 -1.6% 14.19 US$494,465
2023-08-23 2023-08-23 PrS Proposed sale
3.6
Boxer Capital, LLC

Seller's CEO is Director of Issuer

Non-Executive Director
125,000
11.75
US$1,468,750 		125,000 11.75 US$1,468,750
2023-08-23 2023-08-23 PrS Proposed sale
3.6
Boxer Capital, LLC

Seller's CEO is Director of Issuer

Non-Executive Director
225,000
11.75
US$2,643,750 		225,000 11.75 US$2,643,750
2022-06-10 2022-06-09 S Sale
3.0
Hallal David
Non-Executive Director
1,171 -100.0%
19.51
US$22,846 		1,171 -100.0% 19.51 US$22,846
2022-06-10 2022-06-08 S Sale
3.0
Hallal David
Non-Executive Director
10,577 -100.0%
19.86
US$210,059 		10,577 -100.0% 19.86 US$210,059
2022-06-10 2022-06-08 S Sale
3.0
Hallal David
Non-Executive Director
11,899 -100.0%
20.39
US$242,621 		11,899 -100.0% 20.39 US$242,621
2022-06-10 2022-06-08 S Sale
3.0
Hallal David
Non-Executive Director
5,968 -100.0%
20.39
US$121,688 		5,968 -100.0% 20.39 US$121,688
2022-05-11 2022-05-11 S Sale
3.4
Davis Aaron I.
Non-Executive Director
337,109 -13.5%
18.25
US$6,151,801 		337,109 -13.5% 18.25 US$6,151,801
2022-05-11 2022-05-11 S Sale
3.4
Davis Aaron I.
Non-Executive Director
891 -0.0%
17.53
US$15,621 		891 -0.0% 17.53 US$15,621
2022-05-11 2022-05-10 S Sale
3.4
Davis Aaron I.
Non-Executive Director
4,850 -0.2%
24.77
US$120,112 		4,850 -0.2% 24.77 US$120,112
2022-05-11 2022-05-10 S Sale
3.4
Davis Aaron I.
Non-Executive Director
95,150 -3.7%
25.18
US$2,395,858 		95,150 -3.7% 25.18 US$2,395,858
2022-05-11 2022-05-09 S Sale
3.4
Davis Aaron I.
Non-Executive Director
200,000 -7.2%
23.47
US$4,693,120 		200,000 -7.2% 23.47 US$4,693,120
2022-05-11 2022-05-09 S Sale
3.4
Davis Aaron I.
Non-Executive Director
25,000 -0.9%
22.91
US$572,722 		25,000 -0.9% 22.91 US$572,722
2022-05-02 2022-05-02 S Sale
3.4
Davis Aaron I.
Non-Executive Director
92,700 -3.2%
27.53
US$2,552,328 		92,700 -3.2% 27.53 US$2,552,328
2022-05-02 2022-05-02 S Sale
3.4
Davis Aaron I.
Non-Executive Director
7,300 -0.3%
26.91
US$196,406 		7,300 -0.3% 26.91 US$196,406
2022-05-02 2022-04-29 S Sale
3.4
Davis Aaron I.
Non-Executive Director
115,000 -3.8%
27.01
US$3,106,668 		115,000 -3.8% 27.01 US$3,106,668
2022-05-02 2022-04-29 S Sale
3.4
Davis Aaron I.
Non-Executive Director
10,000 -0.3%
28.22
US$282,154 		10,000 -0.3% 28.22 US$282,154
2022-05-02 2022-04-28 S Sale
3.4
Davis Aaron I.
Non-Executive Director
150,000 -4.7%
27.40
US$4,110,315 		150,000 -4.7% 27.40 US$4,110,315
2022-04-19 2022-04-18 S Sale
3.2
Detheux Michel

Chief Executive Officer

Officer
33 -0.1%
32.64
US$1,077 		33 -0.1% 32.64 US$1,077
2022-04-19 2022-04-18 S Sale
3.2
Detheux Michel

Chief Executive Officer

Officer
11,467 -30.4%
31.87
US$365,453 		11,467 -30.4% 31.87 US$365,453
2022-03-24 2022-03-23 B Purchase
3.4
Davis Aaron I.
Non-Executive Director
20,000 +0.6%
32.85
US$656,980 		20,000 +0.6% 32.85 US$656,980
2022-03-24 2022-03-22 B Purchase
3.4
Davis Aaron I.
Non-Executive Director
5,000 +0.2%
33.43
US$167,139 		5,000 +0.2% 33.43 US$167,139
2022-03-24 2022-03-22 B Purchase
3.4
Davis Aaron I.
Non-Executive Director
3,700 +0.1%
33.09
US$122,432 		3,700 +0.1% 33.09 US$122,432
2022-03-24 2022-03-22 B Purchase
3.4
Davis Aaron I.
Non-Executive Director
21,300 +0.7%
31.88
US$678,938 		21,300 +0.7% 31.88 US$678,938
2022-03-22 2022-03-22 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
1,548 -5.6%
36.51
US$56,517 		1,548 -5.6% 36.51 US$56,517
2022-03-22 2022-03-22 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
1,159 -4.0%
35.22
US$40,820 		1,159 -4.0% 35.22 US$40,820
2022-03-22 2022-03-22 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
9,908 -25.5%
34.11
US$337,962 		9,908 -25.5% 34.11 US$337,962
2022-03-22 2022-03-22 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
5,822 -13.0%
33.44
US$194,688 		5,822 -13.0% 33.44 US$194,688
2022-03-18 2022-03-17 S Sale
3.6
Boxer Capital, LLC
Large shareholder
575,201 -15.5%
35.25
US$20,275,835 		575,201 -15.5% 35.25 US$20,275,835
2022-03-14 2022-03-11 S Sale
3.2
Lager Joanne Jenkins

Chief Medical Officer

Officer
3,500 -100.0%
36.01
US$126,035 		3,500 -100.0% 36.01 US$126,035
2022-03-02 2022-03-01 S Sale
3.3
McGrath Yvonne

Chief Scientific Officer

Officer
10,000 -100.0%
36.76
US$367,570 		10,000 -100.0% 36.76 US$367,570
2022-02-24 2022-02-23 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
544 -1.5%
35.32
US$19,214 		544 -1.5% 35.32 US$19,214
2022-02-24 2022-02-23 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
13,956 -28.4%
34.30
US$478,691 		13,956 -28.4% 34.30 US$478,691
2022-02-14 2022-02-11 PlS Planned sale
3.2
Lager Joanne Jenkins

Chief Medical Officer

Officer
1,518 -100.0%
36.27
US$55,058 		1,518 -100.0% 36.27 US$55,058
2022-02-14 2022-02-11 PlS Planned sale
3.2
Lager Joanne Jenkins

Chief Medical Officer

Officer
1,982 -56.6%
35.52
US$70,401 		1,982 -56.6% 35.52 US$70,401
2022-01-26 2022-01-25 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
4,412 -8.2%
36.21
US$159,759 		4,412 -8.2% 36.21 US$159,759
2022-01-26 2022-01-25 PlS Planned sale
3.2
Detheux Michel

Chief Executive Officer

Officer
10,088 -15.8%
35.45
US$357,620 		10,088 -15.8% 35.45 US$357,620
2022-01-18 2022-01-14 PlS Planned sale
3.2
Lager Joanne Jenkins

Chief Medical Officer

Officer
723 -100.0%
39.58
US$28,616 		723 -100.0% 39.58 US$28,616
2022-01-18 2022-01-14 PlS Planned sale
3.2
Lager Joanne Jenkins

Chief Medical Officer

Officer
2,777 -79.3%
39.25
US$108,997 		2,777 -79.3% 39.25 US$108,997
2022-01-06 2022-01-05 S Sale
3.3
MPM BIOVENTURES 2018, L.P.
Large shareholder
18,135 -0.7%
42.03
US$762,214 		18,135 -0.7% 42.03 US$762,214
2022-01-06 2022-01-05 S Sale
3.1
GADICKE ANSBERT
Large shareholder
30,347 -0.7%
42.03
US$1,275,484 		30,347 -0.7% 42.03 US$1,275,484
2022-01-06 2022-01-05 S Sale
3.2
MPM BioVentures 2014, L.P.
Large shareholder
18,135 -0.7%
42.03
US$762,214 		18,135 -0.7% 42.03 US$762,214
2022-01-06 2022-01-04 S Sale
3.3
MPM BIOVENTURES 2018, L.P.
Large shareholder
7,671 -0.3%
46.47
US$356,471 		7,671 -0.3% 46.47 US$356,471
2022-01-06 2022-01-04 S Sale
3.3
MPM BIOVENTURES 2018, L.P.
Large shareholder
6,768 -0.2%
45.32
US$306,726 		6,768 -0.2% 45.32 US$306,726
2022-01-06 2022-01-04 S Sale
3.3
MPM BIOVENTURES 2018, L.P.
Large shareholder
19,366 -0.7%
43.20
US$836,611 		19,366 -0.7% 43.20 US$836,611
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