United States Biotechnology & Medical Research

Denali Therapeutics Inc (DNLI)

Track

Denali Therapeutics Inc. experienced multiple divestment activities involving key personnel, including Carole Ho, Ryan J. Watts, and Alexander O. Schuth. These transactions, primarily proposed or executed sales, concluded on February 5, 2026. Given that these events occurred over three months ago, no assessment regarding current market valuation or recent equity performance is provided.
Ticker: DNLI Exchange: NSM
Preparing chart...
Download chart Copy chart image Copy link Share to X Share


• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
Upgrade for signal details

Upgrade to see score, net flow, insiders and context.

Upgrade to see full signal details →

Insider trades have triggered activity signals for Denali Therapeutics Inc. Upgrade to see score, net flow, insiders and the full signal context.

Open in Activity Signals screener →
Top insiders
Trades
Proposed sale 5 Feb 2026
Value US$1,870,371.47 | Price 49.33 | Shares 6,167
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value 		Number of shares Price Value Details
2026-02-05 2026-02-05 PrS Proposed sale
3.8
CAROLE HO

Former Affiliate
6,167
49.33
US$1,870,371 		6,167 49.33 US$1,870,371
2026-02-04 2026-02-04 PrS Proposed sale
3.8
CAROLE HO

Former Affiliate
18,208
278.95
US$3,065,905 		18,208 278.95 US$3,065,905
2026-02-03 2026-02-03 PrS Proposed sale
3.8
CAROLE HO

Former Affiliate
73,533
303.28
US$2,763,458 		73,533 303.28 US$2,763,458
2026-01-08 2026-01-06 S Sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
17,218 -5.7%
16.50
US$284,097 		17,218 -5.7% 16.50 US$284,097
2026-01-08 2026-01-06 S Sale
3.7
Watts Ryan J.

President and CEO

Executive Director
35,198 -10.6%
16.50
US$580,767 		35,198 -10.6% 16.50 US$580,767
2026-01-06 2026-01-06 PrS Proposed sale
3.8
Ho Carole

Consultant
17,218
16.50
US$284,097 		17,218 16.50 US$284,097
2026-01-06 2026-01-06 PrS Proposed sale
3.6
Schuth Alexander O.

Officer

Officer
17,218
16.50
US$284,097 		17,218 16.50 US$284,097
2026-01-06 2026-01-06 PrS Proposed sale
3.7
Watts Ryan J.

Director; Officer

Executive Director
35,198
16.50
US$580,767 		35,198 16.50 US$580,767
2025-12-04 2025-12-04 PrS Proposed sale
3.8
CAROLE HO

Officer

Officer
1,882
19.00
US$35,758 		1,882 19.00 US$35,758
2025-08-14 2025-08-13 PlS Planned sale
3.8
Ho Carole

Chief Medical Officer

Officer
806 -0.4%
14.64
US$11,800 		806 -0.4% 14.64 US$11,800
2025-08-13 2025-08-13 PrS Proposed sale
3.8
CAROLE HO

Officer

Officer
806
13.22
US$10,655 		806 13.22 US$10,655
2025-08-14 2025-08-12 S Sale
3.8
Ho Carole

Chief Medical Officer

Officer
2,937 -1.3%
13.58
US$39,884 		2,937 -1.3% 13.58 US$39,884
2025-08-14 2025-08-12 S Sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
2,937 -1.2%
13.58
US$39,884 		2,937 -1.2% 13.58 US$39,884
2025-08-12 2025-08-12 PrS Proposed sale
3.6
Schuth Alexander O.

Officer

Officer
2,937
13.58
US$39,876 		2,937 13.58 US$39,876
2025-08-12 2025-08-12 PrS Proposed sale
3.8
Ho Carole

Officer

Officer
2,937
13.58
US$39,876 		2,937 13.58 US$39,876
2025-07-11 2025-07-09 PlS Planned sale
3.7
Watts Ryan J.

President and CEO

Executive Director
495,282 -66.2%
15.00
US$7,429,230 		495,282 -66.2% 15.00 US$7,429,230
2025-07-09 2025-07-09 PrS Proposed sale
3.7
Watts Ryan J.

Officer

Officer
495,282
14.33
US$7,097,391 		495,282 14.33 US$7,097,391
2025-01-08 2025-01-07 S Sale
3.7
Watts Ryan J.

President and CEO

Executive Director
7,650 -2.9%
20.81
US$159,196 		7,650 -2.9% 20.81 US$159,196
2025-01-08 2025-01-07 S Sale
3.8
Ho Carole

Chief Medical Officer

Officer
2,907 -1.6%
20.81
US$60,495 		2,907 -1.6% 20.81 US$60,495
2025-01-08 2025-01-07 S Sale
3.4
Krognes Steve E.
Non-Executive Director
3,339 -11.5%
20.81
US$69,485 		3,339 -11.5% 20.81 US$69,485
2025-01-08 2025-01-07 S Sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
2,907 -1.2%
20.81
US$60,495 		2,907 -1.2% 20.81 US$60,495
2025-01-07 2025-01-07 PrS Proposed sale
3.8
Ho Carole

Officer

Officer
2,907
20.81
US$60,495 		2,907 20.81 US$60,495
2025-01-07 2025-01-07 PrS Proposed sale
3.6
Schuth Alexander O.

Officer

Officer
2,907
20.81
US$60,495 		2,907 20.81 US$60,495
2025-01-07 2025-01-07 PrS Proposed sale
3.7
Watts Ryan J.

Director; Officer

Executive Director
7,650
20.81
US$159,196 		7,650 20.81 US$159,196
2025-01-07 2025-01-07 PrS Proposed sale
3.4
Krognes Steve E.

Director

Non-Executive Director
3,339
20.81
US$69,485 		3,339 20.81 US$69,485
2025-01-08 2025-01-06 S Sale
3.7
Watts Ryan J.

President and CEO

Executive Director
29,266 -10.1%
20.22
US$591,759 		29,266 -10.1% 20.22 US$591,759
2025-01-08 2025-01-06 S Sale
3.8
Ho Carole

Chief Medical Officer

Officer
12,255 -6.4%
20.22
US$247,796 		12,255 -6.4% 20.22 US$247,796
2025-01-08 2025-01-06 S Sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
12,255 -4.7%
20.22
US$247,796 		12,255 -4.7% 20.22 US$247,796
2025-01-07 2025-01-06 PrS Proposed sale
3.6
Schuth Alexander O.

Officer

Officer
12,255
20.22
US$247,781 		12,255 20.22 US$247,781
2025-01-07 2025-01-06 PrS Proposed sale
3.7
Watts Ryan J.

Director; Officer

Executive Director
29,266
20.22
US$591,723 		29,266 20.22 US$591,723
2025-01-07 2025-01-06 PrS Proposed sale
3.8
Ho Carole

Officer

Officer
12,255
20.22
US$247,786 		12,255 20.22 US$247,786
2025-01-03 2025-01-02 PlS Planned sale
SATO VICKI L
Non-Executive Director
3,080 -2.8%
20.91
US$64,403 		3,080 -2.8% 20.91 US$64,403
2025-01-02 2025-01-02 PrS Proposed sale
VICKI LEE SATO

Director

Non-Executive Director
6,160
20.38
US$125,541 		6,160 20.38 US$125,541
2025-01-03 2024-12-31 PlS Planned sale
3.4
Krognes Steve E.
Non-Executive Director
30,000 -50.8%
20.25
US$607,500 		30,000 -50.8% 20.25 US$607,500
2024-11-13 2024-11-11 PlS Planned sale
2.0
Schenkein David P
Non-Executive Director
32,312 -77.8%
32.87
US$1,062,095 		32,312 -77.8% 32.87 US$1,062,095
2024-11-13 2024-11-11 PlS Planned sale
2.0
Schenkein David P
Non-Executive Director
27,129 -39.5%
32.09
US$870,570 		27,129 -39.5% 32.09 US$870,570
2024-11-12 2024-11-11 PrS Proposed sale
2.0
DAVID SCHENKEIN

Director

Non-Executive Director
59,441
31.35
US$1,863,475 		59,441 31.35 US$1,863,475
2024-11-12 2024-11-07 PlS Planned sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
300 -0.2%
31.29
US$9,387 		300 -0.2% 31.29 US$9,387
2024-11-12 2024-11-07 PlS Planned sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
2,925 -1.6%
30.72
US$89,856 		2,925 -1.6% 30.72 US$89,856
2024-11-12 2024-11-07 PlS Planned sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
12,333 -6.4%
29.68
US$366,043 		12,333 -6.4% 29.68 US$366,043
2024-11-12 2024-11-07 PlS Planned sale
SATO VICKI L
Non-Executive Director
1,020 -0.9%
30.00
US$30,600 		1,020 -0.9% 30.00 US$30,600
2024-11-07 2024-11-07 PrS Proposed sale
3.6
ALEXANDER SCHUTH

Officer

Officer
15,558
29.55
US$459,739 		15,558 29.55 US$459,739
2024-11-05 2024-11-01 PlS Planned sale
SATO VICKI L
Non-Executive Director
3,080 -2.7%
27.07
US$83,376 		3,080 -2.7% 27.07 US$83,376
2024-10-22 2024-10-18 PlS Planned sale
3.7
Watts Ryan J.

President and CEO

Executive Director
40,000 -14.5%
27.69
US$1,107,600 		40,000 -14.5% 27.69 US$1,107,600
2024-10-18 2024-10-18 PrS Proposed sale
3.7
RYAN WATTS

Director; Officer

Executive Director
40,000
27.42
US$1,096,800 		40,000 27.42 US$1,096,800
2024-10-02 2024-09-30 PlS Planned sale
3.4
Krognes Steve E.
Non-Executive Director
30,000 -50.8%
29.03
US$870,900 		30,000 -50.8% 29.03 US$870,900
2024-09-16 2024-09-13 PlS Planned sale
SATO VICKI L
Non-Executive Director
1,020 -0.9%
30.00
US$30,600 		1,020 -0.9% 30.00 US$30,600
2024-09-13 2024-09-13 PrS Proposed sale
VICKI LEE SATO

Director

Non-Executive Director
6,160
27.96
US$172,234 		6,160 27.96 US$172,234
2024-09-04 2024-09-03 PlS Planned sale
SATO VICKI L
Non-Executive Director
100 -0.1%
25.37
US$2,537 		100 -0.1% 25.37 US$2,537
2024-09-04 2024-09-03 PlS Planned sale
SATO VICKI L
Non-Executive Director
2,980 -2.5%
24.99
US$74,470 		2,980 -2.5% 24.99 US$74,470
2024-08-22 2024-08-21 PlS Planned sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
2,547 -1.4%
24.78
US$63,115 		2,547 -1.4% 24.78 US$63,115
2024-08-22 2024-08-21 PlS Planned sale
3.8
Ho Carole

Chief Medical Officer

Officer
5,907 -4.7%
24.96
US$147,439 		5,907 -4.7% 24.96 US$147,439
2024-08-22 2024-08-21 PlS Planned sale
3.8
Ho Carole

Chief Medical Officer

Officer
14,098 -10.2%
24.41
US$344,132 		14,098 -10.2% 24.41 US$344,132
2024-08-21 2024-08-21 PrS Proposed sale
3.8
CAROLE HO

Officer

Officer
20,005
23.65
US$473,118 		20,005 23.65 US$473,118
2024-08-21 2024-08-21 PrS Proposed sale
3.6
ALEXANDER SCHUTH

Officer

Officer
2,547
23.65
US$60,237 		2,547 23.65 US$60,237
2024-08-22 2024-08-20 S Sale
3.4
Krognes Steve E.
Non-Executive Director
1,727 -5.0%
23.79
US$41,085 		1,727 -5.0% 23.79 US$41,085
2024-08-22 2024-08-20 PlS Planned sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
3,353 -1.8%
23.54
US$78,930 		3,353 -1.8% 23.54 US$78,930
2024-08-22 2024-08-20 S Sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
2,453 -1.3%
23.79
US$58,357 		2,453 -1.3% 23.79 US$58,357
2024-08-22 2024-08-20 S Sale
3.7
Watts Ryan J.

President and CEO

Executive Director
2,260 -0.9%
23.79
US$53,765 		2,260 -0.9% 23.79 US$53,765
2024-08-22 2024-08-20 S Sale
3.8
Ho Carole

Chief Medical Officer

Officer
2,453 -1.7%
23.79
US$58,357 		2,453 -1.7% 23.79 US$58,357
2024-08-20 2024-08-20 PrS Proposed sale
3.6
ALEXANDER SCHUTH

Officer

Officer
3,353
23.95
US$80,304 		3,353 23.95 US$80,304
2024-08-20 2024-08-20 PrS Proposed sale
3.4
Krognes Steve E.

Director

Non-Executive Director
1,727
23.79
US$41,085 		1,727 23.79 US$41,085
2024-08-20 2024-08-20 PrS Proposed sale
3.6
Schuth Alexander O.

Officer

Officer
2,453
23.79
US$58,357 		2,453 23.79 US$58,357
2024-08-20 2024-08-20 PrS Proposed sale
3.7
Watts Ryan J.

Director; Officer

Executive Director
2,260
23.79
US$53,765 		2,260 23.79 US$53,765
2024-08-20 2024-08-20 PrS Proposed sale
3.8
Ho Carole

Officer

Officer
2,453
23.79
US$58,356 		2,453 23.79 US$58,356
2024-08-15 2024-08-13 S Sale
3.8
Ho Carole

Chief Medical Officer

Officer
2,337 -1.6%
22.89
US$53,494 		2,337 -1.6% 22.89 US$53,494
2024-08-15 2024-08-13 S Sale
3.6
Schuth Alexander O.

COFO and Secretary

Officer
2,272 -1.2%
22.89
US$52,006 		2,272 -1.2% 22.89 US$52,006
2024-08-13 2024-08-13 PrS Proposed sale
3.6
Schuth Alexander O.

Officer

Officer
2,272
22.89
US$52,006 		2,272 22.89 US$52,006
2024-08-13 2024-08-13 PrS Proposed sale
3.8
Ho Carole

Officer

Officer
2,337
22.89
US$53,494 		2,337 22.89 US$53,494
2024-07-03 2024-07-01 PlS Planned sale
SATO VICKI L
Non-Executive Director
100 -0.1%
22.86
US$2,286 		100 -0.1% 22.86 US$2,286
2024-07-03 2024-07-01 PlS Planned sale
SATO VICKI L
Non-Executive Director
2,980 -2.4%
22.12
US$65,918 		2,980 -2.4% 22.12 US$65,918
2024-07-03 2024-07-01 PlS Planned sale
3.4
Krognes Steve E.
Non-Executive Director
100 -0.3%
22.80
US$2,280 		100 -0.3% 22.80 US$2,280
2024-07-03 2024-07-01 PlS Planned sale
3.4
Krognes Steve E.
Non-Executive Director
29,900 -46.4%
22.12
US$661,388 		29,900 -46.4% 22.12 US$661,388
2024-07-01 2024-07-01 PrS Proposed sale
VICKI LEE SATO

Director

Non-Executive Director
6,160
23.22
US$143,035 		6,160 23.22 US$143,035
2024-07-01 2024-07-01 PrS Proposed sale
3.4
STEVE KROGNES

Director

Non-Executive Director
30,000
23.22
US$696,600 		30,000 23.22 US$696,600
Explore more

More insider trading research around Denali Therapeutics Inc

More insider trades in United States
Similar Healthcare companies with insider activity
More Pharmaceuticals & Medical Research companies with insider activity
More Biotechnology & Medical Research companies with insider activity
Insider trading in North America