Denali Therapeutics Inc. (DNLI)

Denali Therapeutics Inc. experienced nine insider trading transactions over the past ninety days, resulting in a net negative value of approximately $108,493. Executives exclusively sold shares during this period. These activities follow recent results financiers where the firm beat earnings expectations, despite a stock price decline of 18% over the last quarter.
Ticker: DNLI Exchange: NSM


Loading...
• Purchase • Sale • Planned purchase • Planned sale Net purchase Net sale Buy signal Sell signal Earnings
Upgrade for signal details

Upgrade to see score, net flow, insiders and context.

Upgrade to see full signal details →

Insider trades have triggered activity signals for Denali Therapeutics Inc.. Upgrade to see score, net flow, insiders and the full signal context.

Top insiders
Trades
Abbreviations B: Buy, S: Sell, PP: Planned purchase, PlS: Planned sale, PrS: Proposed sale, O: Option / Other
Chin Peter Scott Chief Medical Officer Officer
Transaction date
Sale
Price
16.32
Quantity 57,580 -31.5%
Value US$888,805
Chin Peter Scott Officer Officer
Transaction date
Proposed sale
Price
24.01
Quantity 92,446
Value US$3,327,331
Thornberry Nancy Non-Executive Director
Transaction date
Planned sale
Price
232.32
Quantity 21,146 -40.0%
Value US$4,346,160
Thornberry Nancy Non-Executive Director
Transaction date
Planned sale
Price
22.85
Quantity 1,000 -34.8%
Value US$100,000
NANCY THORNBERRY Director Non-Executive Director
Transaction date
Proposed sale
Price
23.27
Quantity 11,439
Value US$266,128
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Planned sale
Price
23.44
Quantity 2,768 -1.0%
Value US$64,882
3.6
ALEXANDER SCHUTH Officer Officer
Transaction date
Proposed sale
Price
23.76
Quantity 2,768
Value US$65,768
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Sale
Price
25.07
Quantity 2,857 -1.0%
Value US$71,625
3.6
Schuth Alexander O. Officer Officer
Transaction date
Proposed sale
Price
25.07
Quantity 2,857
Value US$71,624
3.8
CAROLE HO Former Affiliate
Transaction date
Proposed sale
Price
20.29
Quantity 39,490
Value US$801,394
3.8
CAROLE HO Former Affiliate
Transaction date
Proposed sale
Price
21.18
Quantity 150,000
Value US$3,176,970
3.8
CAROLE HO Former Affiliate
Transaction date
Proposed sale
Price
22.16
Quantity 150,000
Value US$3,324,060
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Sale
Price
16.50
Quantity 17,218 -5.7%
Value US$284,097
3.7
Watts Ryan J. President and CEO Executive Director
Transaction date
Sale
Price
16.50
Quantity 35,198 -10.6%
Value US$580,767
3.8
Ho Carole Consultant
Transaction date
Proposed sale
Price
16.50
Quantity 17,218
Value US$284,097
3.6
Schuth Alexander O. Officer Officer
Transaction date
Proposed sale
Price
16.50
Quantity 17,218
Value US$284,097
3.7
Watts Ryan J. Director; Officer Executive Director
Transaction date
Proposed sale
Price
16.50
Quantity 35,198
Value US$580,767
3.8
CAROLE HO Officer Officer
Transaction date
Proposed sale
Price
19.00
Quantity 1,882
Value US$35,758
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Planned sale
Price
14.64
Quantity 806 -0.4%
Value US$11,800
3.8
CAROLE HO Officer Officer
Transaction date
Proposed sale
Price
13.22
Quantity 806
Value US$10,655
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Sale
Price
13.58
Quantity 2,937 -1.3%
Value US$39,884
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Sale
Price
13.58
Quantity 2,937 -1.2%
Value US$39,884
3.6
Schuth Alexander O. Officer Officer
Transaction date
Proposed sale
Price
13.58
Quantity 2,937
Value US$39,876
3.8
Ho Carole Officer Officer
Transaction date
Proposed sale
Price
13.58
Quantity 2,937
Value US$39,876
3.7
Watts Ryan J. President and CEO Executive Director
Transaction date
Planned sale
Price
15.00
Quantity 495,282 -66.2%
Value US$7,429,230
3.7
Watts Ryan J. Officer Officer
Transaction date
Proposed sale
Price
14.33
Quantity 495,282
Value US$7,097,391
3.7
Watts Ryan J. President and CEO Executive Director
Transaction date
Sale
Price
20.81
Quantity 7,650 -2.9%
Value US$159,196
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Sale
Price
20.81
Quantity 2,907 -1.6%
Value US$60,495
3.0
Krognes Steve E. Non-Executive Director
Transaction date
Sale
Price
20.81
Quantity 3,339 -11.5%
Value US$69,485
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Sale
Price
20.81
Quantity 2,907 -1.2%
Value US$60,495
3.8
Ho Carole Officer Officer
Transaction date
Proposed sale
Price
20.81
Quantity 2,907
Value US$60,495
3.6
Schuth Alexander O. Officer Officer
Transaction date
Proposed sale
Price
20.81
Quantity 2,907
Value US$60,495
3.7
Watts Ryan J. Director; Officer Executive Director
Transaction date
Proposed sale
Price
20.81
Quantity 7,650
Value US$159,196
3.0
Krognes Steve E. Director Non-Executive Director
Transaction date
Proposed sale
Price
20.81
Quantity 3,339
Value US$69,485
3.7
Watts Ryan J. President and CEO Executive Director
Transaction date
Sale
Price
20.22
Quantity 29,266 -10.1%
Value US$591,759
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Sale
Price
20.22
Quantity 12,255 -6.4%
Value US$247,796
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Sale
Price
20.22
Quantity 12,255 -4.7%
Value US$247,796
3.6
Schuth Alexander O. Officer Officer
Transaction date
Proposed sale
Price
20.22
Quantity 12,255
Value US$247,781
3.7
Watts Ryan J. Director; Officer Executive Director
Transaction date
Proposed sale
Price
20.22
Quantity 29,266
Value US$591,723
3.8
Ho Carole Officer Officer
Transaction date
Proposed sale
Price
20.22
Quantity 12,255
Value US$247,786
SATO VICKI L Non-Executive Director
Transaction date
Planned sale
Price
20.91
Quantity 3,080 -2.8%
Value US$64,403
VICKI LEE SATO Director Non-Executive Director
Transaction date
Proposed sale
Price
20.38
Quantity 6,160
Value US$125,541
3.0
Krognes Steve E. Non-Executive Director
Transaction date
Planned sale
Price
20.25
Quantity 30,000 -50.8%
Value US$607,500
2.0
Schenkein David P Non-Executive Director
Transaction date
Planned sale
Price
32.87
Quantity 32,312 -77.8%
Value US$1,062,095
2.0
Schenkein David P Non-Executive Director
Transaction date
Planned sale
Price
32.09
Quantity 27,129 -39.5%
Value US$870,570
2.0
DAVID SCHENKEIN Director Non-Executive Director
Transaction date
Proposed sale
Price
31.35
Quantity 59,441
Value US$1,863,475
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Planned sale
Price
31.29
Quantity 300 -0.2%
Value US$9,387
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Planned sale
Price
30.72
Quantity 2,925 -1.6%
Value US$89,856
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Planned sale
Price
29.68
Quantity 12,333 -6.4%
Value US$366,043
SATO VICKI L Non-Executive Director
Transaction date
Planned sale
Price
30.00
Quantity 1,020 -0.9%
Value US$30,600
3.6
ALEXANDER SCHUTH Officer Officer
Transaction date
Proposed sale
Price
29.55
Quantity 15,558
Value US$459,739
SATO VICKI L Non-Executive Director
Transaction date
Planned sale
Price
27.07
Quantity 3,080 -2.7%
Value US$83,376
3.7
Watts Ryan J. President and CEO Executive Director
Transaction date
Planned sale
Price
27.69
Quantity 40,000 -14.5%
Value US$1,107,600
3.7
RYAN WATTS Director; Officer Executive Director
Transaction date
Proposed sale
Price
27.42
Quantity 40,000
Value US$1,096,800
3.0
Krognes Steve E. Non-Executive Director
Transaction date
Planned sale
Price
29.03
Quantity 30,000 -50.8%
Value US$870,900
SATO VICKI L Non-Executive Director
Transaction date
Planned sale
Price
30.00
Quantity 1,020 -0.9%
Value US$30,600
VICKI LEE SATO Director Non-Executive Director
Transaction date
Proposed sale
Price
27.96
Quantity 6,160
Value US$172,234
SATO VICKI L Non-Executive Director
Transaction date
Planned sale
Price
25.37
Quantity 100 -0.1%
Value US$2,537
SATO VICKI L Non-Executive Director
Transaction date
Planned sale
Price
24.99
Quantity 2,980 -2.5%
Value US$74,470
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Planned sale
Price
24.78
Quantity 2,547 -1.4%
Value US$63,115
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Planned sale
Price
24.96
Quantity 5,907 -4.7%
Value US$147,439
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Planned sale
Price
24.41
Quantity 14,098 -10.2%
Value US$344,132
3.8
CAROLE HO Officer Officer
Transaction date
Proposed sale
Price
23.65
Quantity 20,005
Value US$473,118
3.6
ALEXANDER SCHUTH Officer Officer
Transaction date
Proposed sale
Price
23.65
Quantity 2,547
Value US$60,237
3.0
Krognes Steve E. Non-Executive Director
Transaction date
Sale
Price
23.79
Quantity 1,727 -5.0%
Value US$41,085
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Planned sale
Price
23.54
Quantity 3,353 -1.8%
Value US$78,930
3.6
Schuth Alexander O. COFO and Secretary Officer
Transaction date
Sale
Price
23.79
Quantity 2,453 -1.3%
Value US$58,357
3.7
Watts Ryan J. President and CEO Executive Director
Transaction date
Sale
Price
23.79
Quantity 2,260 -0.9%
Value US$53,765
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Sale
Price
23.79
Quantity 2,453 -1.7%
Value US$58,357
3.6
ALEXANDER SCHUTH Officer Officer
Transaction date
Proposed sale
Price
23.95
Quantity 3,353
Value US$80,304
3.0
Krognes Steve E. Director Non-Executive Director
Transaction date
Proposed sale
Price
23.79
Quantity 1,727
Value US$41,085
3.6
Schuth Alexander O. Officer Officer
Transaction date
Proposed sale
Price
23.79
Quantity 2,453
Value US$58,357
3.7
Watts Ryan J. Director; Officer Executive Director
Transaction date
Proposed sale
Price
23.79
Quantity 2,260
Value US$53,765
3.8
Ho Carole Officer Officer
Transaction date
Proposed sale
Price
23.79
Quantity 2,453
Value US$58,356
3.8
Ho Carole Chief Medical Officer Officer
Transaction date
Sale
Price
22.89
Quantity 2,337 -1.6%
Value US$53,494
Notification date Transaction date B/S Transaction type Insider and/or position Nb. shares
Price
Value
Number of shares Price Value Details
2026-09-09 2026-09-04 S Sale

Chief Medical Officer

Officer
57,580 -31.5%
16.32
US$888,805
57,580 -31.5% 16.32 US$888,805
2026-09-04 2026-09-04 PrS Proposed sale

Officer

Officer
92,446
24.01
US$3,327,331
92,446 24.01 US$3,327,331
2026-09-04 2026-09-02 PlS Planned sale Non-Executive Director
21,146 -40.0%
232.32
US$4,346,160
21,146 -40.0% 232.32 US$4,346,160
2026-09-04 2026-09-02 PlS Planned sale Non-Executive Director
1,000 -34.8%
22.85
US$100,000
1,000 -34.8% 22.85 US$100,000
2026-09-02 2026-09-02 PrS Proposed sale

Director

Non-Executive Director
11,439
23.27
US$266,128
11,439 23.27 US$266,128
2026-09-03 2026-09-01 PlS Planned sale

COFO and Secretary

Officer
2,768 -1.0%
23.44
US$64,882
2,768 -1.0% 23.44 US$64,882
2026-09-01 2026-09-01 PrS Proposed sale

Officer

Officer
2,768
23.76
US$65,768
2,768 23.76 US$65,768
2026-08-13 2026-08-11 S Sale

COFO and Secretary

Officer
2,857 -1.0%
25.07
US$71,625
2,857 -1.0% 25.07 US$71,625
2026-08-11 2026-08-11 PrS Proposed sale

Officer

Officer
2,857
25.07
US$71,624
2,857 25.07 US$71,624
2026-02-05 2026-02-05 PrS Proposed sale

Former Affiliate

39,490
20.29
US$801,394
39,490 20.29 US$801,394
2026-02-04 2026-02-04 PrS Proposed sale

Former Affiliate

150,000
21.18
US$3,176,970
150,000 21.18 US$3,176,970
2026-02-03 2026-02-03 PrS Proposed sale

Former Affiliate

150,000
22.16
US$3,324,060
150,000 22.16 US$3,324,060
2026-01-08 2026-01-06 S Sale

COFO and Secretary

Officer
17,218 -5.7%
16.50
US$284,097
17,218 -5.7% 16.50 US$284,097
2026-01-08 2026-01-06 S Sale

President and CEO

Executive Director
35,198 -10.6%
16.50
US$580,767
35,198 -10.6% 16.50 US$580,767
2026-01-06 2026-01-06 PrS Proposed sale

Consultant

17,218
16.50
US$284,097
17,218 16.50 US$284,097
2026-01-06 2026-01-06 PrS Proposed sale

Officer

Officer
17,218
16.50
US$284,097
17,218 16.50 US$284,097
2026-01-06 2026-01-06 PrS Proposed sale

Director; Officer

Executive Director
35,198
16.50
US$580,767
35,198 16.50 US$580,767
2025-12-04 2025-12-04 PrS Proposed sale

Officer

Officer
1,882
19.00
US$35,758
1,882 19.00 US$35,758
2025-08-14 2025-08-13 PlS Planned sale

Chief Medical Officer

Officer
806 -0.4%
14.64
US$11,800
806 -0.4% 14.64 US$11,800
2025-08-13 2025-08-13 PrS Proposed sale

Officer

Officer
806
13.22
US$10,655
806 13.22 US$10,655
2025-08-14 2025-08-12 S Sale

Chief Medical Officer

Officer
2,937 -1.3%
13.58
US$39,884
2,937 -1.3% 13.58 US$39,884
2025-08-14 2025-08-12 S Sale

COFO and Secretary

Officer
2,937 -1.2%
13.58
US$39,884
2,937 -1.2% 13.58 US$39,884
2025-08-12 2025-08-12 PrS Proposed sale

Officer

Officer
2,937
13.58
US$39,876
2,937 13.58 US$39,876
2025-08-12 2025-08-12 PrS Proposed sale

Officer

Officer
2,937
13.58
US$39,876
2,937 13.58 US$39,876
2025-07-11 2025-07-09 PlS Planned sale

President and CEO

Executive Director
495,282 -66.2%
15.00
US$7,429,230
495,282 -66.2% 15.00 US$7,429,230
2025-07-09 2025-07-09 PrS Proposed sale

Officer

Officer
495,282
14.33
US$7,097,391
495,282 14.33 US$7,097,391
2025-01-08 2025-01-07 S Sale

President and CEO

Executive Director
7,650 -2.9%
20.81
US$159,196
7,650 -2.9% 20.81 US$159,196
2025-01-08 2025-01-07 S Sale

Chief Medical Officer

Officer
2,907 -1.6%
20.81
US$60,495
2,907 -1.6% 20.81 US$60,495
2025-01-08 2025-01-07 S Sale Non-Executive Director
3,339 -11.5%
20.81
US$69,485
3,339 -11.5% 20.81 US$69,485
2025-01-08 2025-01-07 S Sale

COFO and Secretary

Officer
2,907 -1.2%
20.81
US$60,495
2,907 -1.2% 20.81 US$60,495
2025-01-07 2025-01-07 PrS Proposed sale

Officer

Officer
2,907
20.81
US$60,495
2,907 20.81 US$60,495
2025-01-07 2025-01-07 PrS Proposed sale

Officer

Officer
2,907
20.81
US$60,495
2,907 20.81 US$60,495
2025-01-07 2025-01-07 PrS Proposed sale

Director; Officer

Executive Director
7,650
20.81
US$159,196
7,650 20.81 US$159,196
2025-01-07 2025-01-07 PrS Proposed sale

Director

Non-Executive Director
3,339
20.81
US$69,485
3,339 20.81 US$69,485
2025-01-08 2025-01-06 S Sale

President and CEO

Executive Director
29,266 -10.1%
20.22
US$591,759
29,266 -10.1% 20.22 US$591,759
2025-01-08 2025-01-06 S Sale

Chief Medical Officer

Officer
12,255 -6.4%
20.22
US$247,796
12,255 -6.4% 20.22 US$247,796
2025-01-08 2025-01-06 S Sale

COFO and Secretary

Officer
12,255 -4.7%
20.22
US$247,796
12,255 -4.7% 20.22 US$247,796
2025-01-07 2025-01-06 PrS Proposed sale

Officer

Officer
12,255
20.22
US$247,781
12,255 20.22 US$247,781
2025-01-07 2025-01-06 PrS Proposed sale

Director; Officer

Executive Director
29,266
20.22
US$591,723
29,266 20.22 US$591,723
2025-01-07 2025-01-06 PrS Proposed sale

Officer

Officer
12,255
20.22
US$247,786
12,255 20.22 US$247,786
2025-01-03 2025-01-02 PlS Planned sale Non-Executive Director
3,080 -2.8%
20.91
US$64,403
3,080 -2.8% 20.91 US$64,403
2025-01-02 2025-01-02 PrS Proposed sale

Director

Non-Executive Director
6,160
20.38
US$125,541
6,160 20.38 US$125,541
2025-01-03 2024-12-31 PlS Planned sale Non-Executive Director
30,000 -50.8%
20.25
US$607,500
30,000 -50.8% 20.25 US$607,500
2024-11-13 2024-11-11 PlS Planned sale Non-Executive Director
32,312 -77.8%
32.87
US$1,062,095
32,312 -77.8% 32.87 US$1,062,095
2024-11-13 2024-11-11 PlS Planned sale Non-Executive Director
27,129 -39.5%
32.09
US$870,570
27,129 -39.5% 32.09 US$870,570
2024-11-12 2024-11-11 PrS Proposed sale

Director

Non-Executive Director
59,441
31.35
US$1,863,475
59,441 31.35 US$1,863,475
2024-11-12 2024-11-07 PlS Planned sale

COFO and Secretary

Officer
300 -0.2%
31.29
US$9,387
300 -0.2% 31.29 US$9,387
2024-11-12 2024-11-07 PlS Planned sale

COFO and Secretary

Officer
2,925 -1.6%
30.72
US$89,856
2,925 -1.6% 30.72 US$89,856
2024-11-12 2024-11-07 PlS Planned sale

COFO and Secretary

Officer
12,333 -6.4%
29.68
US$366,043
12,333 -6.4% 29.68 US$366,043
2024-11-12 2024-11-07 PlS Planned sale Non-Executive Director
1,020 -0.9%
30.00
US$30,600
1,020 -0.9% 30.00 US$30,600
2024-11-07 2024-11-07 PrS Proposed sale

Officer

Officer
15,558
29.55
US$459,739
15,558 29.55 US$459,739
2024-11-05 2024-11-01 PlS Planned sale Non-Executive Director
3,080 -2.7%
27.07
US$83,376
3,080 -2.7% 27.07 US$83,376
2024-10-22 2024-10-18 PlS Planned sale

President and CEO

Executive Director
40,000 -14.5%
27.69
US$1,107,600
40,000 -14.5% 27.69 US$1,107,600
2024-10-18 2024-10-18 PrS Proposed sale

Director; Officer

Executive Director
40,000
27.42
US$1,096,800
40,000 27.42 US$1,096,800
2024-10-02 2024-09-30 PlS Planned sale Non-Executive Director
30,000 -50.8%
29.03
US$870,900
30,000 -50.8% 29.03 US$870,900
2024-09-16 2024-09-13 PlS Planned sale Non-Executive Director
1,020 -0.9%
30.00
US$30,600
1,020 -0.9% 30.00 US$30,600
2024-09-13 2024-09-13 PrS Proposed sale

Director

Non-Executive Director
6,160
27.96
US$172,234
6,160 27.96 US$172,234
2024-09-04 2024-09-03 PlS Planned sale Non-Executive Director
100 -0.1%
25.37
US$2,537
100 -0.1% 25.37 US$2,537
2024-09-04 2024-09-03 PlS Planned sale Non-Executive Director
2,980 -2.5%
24.99
US$74,470
2,980 -2.5% 24.99 US$74,470
2024-08-22 2024-08-21 PlS Planned sale

COFO and Secretary

Officer
2,547 -1.4%
24.78
US$63,115
2,547 -1.4% 24.78 US$63,115
2024-08-22 2024-08-21 PlS Planned sale

Chief Medical Officer

Officer
5,907 -4.7%
24.96
US$147,439
5,907 -4.7% 24.96 US$147,439
2024-08-22 2024-08-21 PlS Planned sale

Chief Medical Officer

Officer
14,098 -10.2%
24.41
US$344,132
14,098 -10.2% 24.41 US$344,132
2024-08-21 2024-08-21 PrS Proposed sale

Officer

Officer
20,005
23.65
US$473,118
20,005 23.65 US$473,118
2024-08-21 2024-08-21 PrS Proposed sale

Officer

Officer
2,547
23.65
US$60,237
2,547 23.65 US$60,237
2024-08-22 2024-08-20 S Sale Non-Executive Director
1,727 -5.0%
23.79
US$41,085
1,727 -5.0% 23.79 US$41,085
2024-08-22 2024-08-20 PlS Planned sale

COFO and Secretary

Officer
3,353 -1.8%
23.54
US$78,930
3,353 -1.8% 23.54 US$78,930
2024-08-22 2024-08-20 S Sale

COFO and Secretary

Officer
2,453 -1.3%
23.79
US$58,357
2,453 -1.3% 23.79 US$58,357
2024-08-22 2024-08-20 S Sale

President and CEO

Executive Director
2,260 -0.9%
23.79
US$53,765
2,260 -0.9% 23.79 US$53,765
2024-08-22 2024-08-20 S Sale

Chief Medical Officer

Officer
2,453 -1.7%
23.79
US$58,357
2,453 -1.7% 23.79 US$58,357
2024-08-20 2024-08-20 PrS Proposed sale

Officer

Officer
3,353
23.95
US$80,304
3,353 23.95 US$80,304
2024-08-20 2024-08-20 PrS Proposed sale

Director

Non-Executive Director
1,727
23.79
US$41,085
1,727 23.79 US$41,085
2024-08-20 2024-08-20 PrS Proposed sale

Officer

Officer
2,453
23.79
US$58,357
2,453 23.79 US$58,357
2024-08-20 2024-08-20 PrS Proposed sale

Director; Officer

Executive Director
2,260
23.79
US$53,765
2,260 23.79 US$53,765
2024-08-20 2024-08-20 PrS Proposed sale

Officer

Officer
2,453
23.79
US$58,356
2,453 23.79 US$58,356
2024-08-15 2024-08-13 S Sale

Chief Medical Officer

Officer
2,337 -1.6%
22.89
US$53,494
2,337 -1.6% 22.89 US$53,494