|
2017-09-20 |
2017-09-20 |
B
Purchase
|
THOMPSON JOHN CRAIG
President & CEO
|
98,633
+48.6%
424.26
US$1,842,586
|
98,633
+48.6%
|
424.26
|
US$1,842,586
|
|
|
2017-09-07 |
2017-09-07 |
B
Purchase
|
TRUEX PAUL F
|
13,416
+12.1%
351.45
US$3,455,945
|
13,416
+12.1%
|
351.45
|
US$3,455,945
|
|
|
2015-11-18 |
2015-11-13 |
PlS
Planned sale
|
Hislop Colin
Chief Medical Officer
Officer
|
87,810
-28.3%
376.35
US$3,798,842
|
87,810
-28.3%
|
376.35
|
US$3,798,842
|
|
|
2015-11-12 |
2015-11-11 |
S
Sale
|
Hislop Colin
Chief Medical Officer
Officer
|
5,000
-20.7%
5.38
US$26,900
|
5,000
-20.7%
|
5.38
|
US$26,900
|
|
|
2013-06-26 |
2013-06-24 |
B
Purchase
|
Thompson David E.
Non-Executive Director
|
100,000
+354.6%
0.53
US$53,000
|
100,000
+354.6%
|
0.53
|
US$53,000
|
|
|
2013-06-04 |
2013-05-31 |
B
Purchase
|
DZIURZYNSKI BOGDAN
Non-Executive Director
|
10,000
+inf%
0.59
US$5,900
|
10,000
+inf%
|
0.59
|
US$5,900
|
|
|
2013-02-01 |
2013-01-30 |
B
Purchase
|
ORBIMED ADVISORS LLC
Non-Executive Director
|
5,700,000
+323.5%
0.66
US$3,762,000
|
5,700,000
+323.5%
|
0.66
|
US$3,762,000
|
|
|
2013-01-29 |
2013-01-25 |
B
Purchase
|
ORBIMED ADVISORS LLC
Non-Executive Director
|
1,762,000
+inf%
0.65
US$1,142,481
|
1,762,000
+inf%
|
0.65
|
US$1,142,481
|
|
|
2012-07-03 |
2012-06-29 |
S
Sale
|
ORBIMED ADVISORS LLC
Non-Executive Director
|
1,283,300
-100.0%
0.73
US$942,071
|
1,283,300
-100.0%
|
0.73
|
US$942,071
|
|
|
2012-07-02 |
2012-06-29 |
B
Purchase
|
HENNEY CHRISTOPHER S
Non-Executive Director
|
100,000
+inf%
0.75
US$74,930
|
100,000
+inf%
|
0.75
|
US$74,930
|
|
|
2012-07-02 |
2012-06-29 |
B
Purchase
|
HENNEY CHRISTOPHER S
Non-Executive Director
|
100,000
+97.6%
0.75
US$74,930
|
100,000
+97.6%
|
0.75
|
US$74,930
|
|
|
2012-07-02 |
2012-06-29 |
B
Purchase
|
TRUEX PAUL F
President and CEO
Executive Director
|
20,000
+3.2%
0.76
US$15,200
|
20,000
+3.2%
|
0.76
|
US$15,200
|
|
|
2012-03-22 |
2012-03-22 |
S
Sale
|
ORBIMED ADVISORS LLC
Non-Executive Director
|
1,306,700
-50.5%
2.40
US$3,140,131
|
1,306,700
-50.5%
|
2.40
|
US$3,140,131
|
|
|
2012-03-22 |
2012-03-21 |
S
Sale
|
ORBIMED ADVISORS LLC
Non-Executive Director
|
125,000
-4.6%
2.87
US$358,312
|
125,000
-4.6%
|
2.87
|
US$358,312
|
|
|
2012-03-22 |
2012-03-20 |
S
Sale
|
ORBIMED ADVISORS LLC
Non-Executive Director
|
116,800
-4.1%
2.90
US$338,638
|
116,800
-4.1%
|
2.90
|
US$338,638
|
|
|
2012-01-03 |
2011-12-30 |
S
Sale
|
HEALY JAMES
Non-Executive Director
Large shareholder
|
280
-0.6%
6.23
US$1,743
|
280
-0.6%
|
6.23
|
US$1,743
|
|
|
2012-01-03 |
2011-12-30 |
S
Sale
|
HEALY JAMES
Non-Executive Director
Large shareholder
|
4,090
-0.6%
6.23
US$25,460
|
4,090
-0.6%
|
6.23
|
US$25,460
|
|
|
2012-01-03 |
2011-12-30 |
S
Sale
|
SOFINNOVA VENTURE PARTNERS VI L P
Large shareholder
|
280
-0.6%
6.23
US$1,743
|
280
-0.6%
|
6.23
|
US$1,743
|
|
|
2012-01-03 |
2011-12-30 |
S
Sale
|
SOFINNOVA VENTURE PARTNERS VI L P
Large shareholder
|
4,090
-0.6%
6.23
US$25,460
|
4,090
-0.6%
|
6.23
|
US$25,460
|
|
|
2012-01-03 |
2011-12-30 |
S
Sale
|
HEALY JAMES
Non-Executive Director
Large shareholder
|
20,630
-0.6%
6.23
US$128,422
|
20,630
-0.6%
|
6.23
|
US$128,422
|
|